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Recursion Pharmaceuticals (RXRX)
NASDAQ:RXRX
US Market

Recursion Pharmaceuticals (RXRX) AI Stock Analysis

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RXRX

Recursion Pharmaceuticals

(NASDAQ:RXRX)

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Neutral 52 (OpenAI - 4o)
Rating:52Neutral
Price Target:
$5.00
▲(6.84% Upside)
Recursion Pharmaceuticals' overall stock score reflects its financial challenges and mixed technical indicators. However, positive corporate events and a strategic outlook from the earnings call provide some optimism. The company's innovative platform and partnerships offer potential for future growth, but financial instability and valuation concerns weigh heavily on the score.
Positive Factors
Strong Financial Position
A strong cash position ensures operational stability and flexibility to invest in R&D, supporting long-term growth without immediate need for external funding.
Innovative Drug Discovery Platform
The advanced platform enhances Recursion's drug discovery capabilities, potentially accelerating the development of new therapies and strengthening its competitive edge.
Positive Clinical Trial Results
Successful trial outcomes for REC-4881 validate Recursion's AI-driven approach, potentially leading to new treatment options and strengthening its market position.
Negative Factors
Declining Revenue
Declining revenue trends raise concerns about the company's ability to sustain operations and fund future growth initiatives, impacting long-term viability.
Negative Profit Margins
Persistent negative profit margins indicate challenges in cost management and profitability, potentially limiting the company's ability to reinvest in growth.
Challenges in Drug Safety
Safety challenges in drug development can delay product launches and increase R&D costs, impacting Recursion's ability to bring new therapies to market.

Recursion Pharmaceuticals (RXRX) vs. SPDR S&P 500 ETF (SPY)

Recursion Pharmaceuticals Business Overview & Revenue Model

Company DescriptionRecursion Pharmaceuticals, Inc. operates as a clinical-stage biotechnology company, engages in the decoding biology by integrating technological innovations across biology, chemistry, automation, data science, and engineering to industrialize drug discovery. The company develops REC-994, which is in Phase IIa clinical trial to treat cerebral cavernous malformation; REC-2282 for the treatment of neurofibromatosis type 2; REC-4881 to treat familial adenomatous polyposis; and REC-3599, which is in Phase I clinical trial to treat GM2 gangliosidosis. Its preclinical stage product includes REC-3964 to treat Clostridium difficile colitis; REC-64917 for the treat of neural or systemic inflammation; REC-65029 to treat HRD-negative ovarian cancer; REC-648918 to enhance anti-tumor immune; REC-2029 for the treatment of wnt-mutant hepatocellular carcinoma; REC-14221 to treat solid and hematological malignancies; and REC-64151 for the treatment of immune checkpoint resistance in KRAS/STK11 mutant non-small cell lung cancer. The company has collaboration and agreement with Bayer AG; the University of Utah Research Foundation; Ohio State Innovation Foundation; Chromaderm, Inc.; and Takeda Pharmaceutical Company Limited. Recursion Pharmaceuticals, Inc. was incorporated in 2013 and is headquartered in Salt Lake City, Utah.
How the Company Makes MoneyRecursion Pharmaceuticals generates revenue primarily through collaborations and partnerships with pharmaceutical companies and research institutions, wherein it licenses its technology and shares the resulting drug development costs and potential profits. Additionally, the company may receive milestone payments and royalties based on the commercial success of products developed through these partnerships. Recursion also invests in its own drug candidates, aiming to bring novel therapies to market, which can generate revenue through sales once these products are approved by regulatory agencies.

Recursion Pharmaceuticals Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Breaks down revenue by different business units or product lines, highlighting which areas are driving growth and which may need strategic adjustments. This insight helps assess the company's diversification and dependency on specific segments.
Chart InsightsRecursion Pharmaceuticals' revenue from grants has been volatile, with a notable spike in late 2023, but has since declined, reflecting potential shifts in funding sources or project completions. Operating revenue shows a strong upward trajectory, underscoring successful partnerships and technological advancements like Boltz-2 and ClinTech. The earnings call highlights strategic collaborations and financial resilience, projecting a reduced cash burn and a robust cash runway. However, challenges in key programs like CDK7 and FAP could impact future revenue streams, necessitating careful monitoring of clinical and regulatory developments.
Data provided by:The Fly

Recursion Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 05, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 04, 2026
Earnings Call Sentiment Positive
The earnings call reflected a positive outlook with strong leadership transitions, a robust financial position, and significant achievements in partnerships and platform development. However, there are challenges related to drug safety and clinical uncertainty that require careful management.
Q3-2025 Updates
Positive Updates
New Leadership Announcement
Najat Khan will become the new CEO, President, and Director of Recursion from January 1, 2026. Chris Gibson will continue as the Chairman of the Board and Executive Adviser.
Strong Financial Position
Recursion holds a pro forma cash balance of $785 million, providing runway through the end of 2027 without additional financing.
Significant Partnership Milestone
Recursion earned a $30 million milestone payment from Roche and Genentech for the delivery of a whole genome neuro map, contributing to over $500 million in total partnership inflows.
Advanced Drug Discovery Platform
Recursion has developed an automated ADMET platform for drug-like molecule design and has delivered the world's largest iPSC-derived neuronal and microglial cell maps.
Negative Updates
Challenges in Safety and Tolerability
CDK7 therapeutic development faces challenges due to a narrow therapeutic window and GI-related toxicities, though efforts are being made to optimize dosing schedules.
Uncertainty in Clinical Outcomes
Ongoing trials for CDK7 and REC-4881 are in early stages, with some data showing manageable safety profiles, but full efficacy data and long-term outcomes remain to be seen.
Company Guidance
During Recursion's Third Quarter 2025 earnings call, several key metrics and strategic updates were discussed. The company highlighted its strong financial position with a pro forma cash balance of nearly $800 million, providing a runway through the end of 2027 without additional financing. Recursion has achieved over $0.5 billion in total cash inflows from partnerships, underscored by a recent $30 million milestone payment from Roche and Genentech. The company is advancing its drug discovery efforts, notably with the development of whole genome maps in neuroscience and GI oncology. Additionally, Recursion reaffirmed its guidance for 2025 expenses to be under $450 million and expects less than $390 million in 2026, reflecting a 35% reduction in expenses from 2024. The platform's integration and cross-partner collaborations, such as with Sanofi, aim to generate significant value and drive future growth. As Najat Khan transitions to the CEO role from January 1, 2026, the company remains focused on translating platform insights into clinical proofs and sustainable value creation.

Recursion Pharmaceuticals Financial Statement Overview

Summary
Recursion Pharmaceuticals is facing significant financial challenges, with declining revenues and persistent losses impacting profitability and cash flow. While the company maintains a low level of debt, its inability to generate positive returns on equity and cash from operations poses risks to its financial stability. Continued focus on cost management and revenue growth is essential for improving financial performance.
Income Statement
20
Very Negative
Recursion Pharmaceuticals has been experiencing declining revenue, with a significant drop of 32.44% in the TTM period. The company also faces negative profit margins, with a net profit margin of -10.07% and an EBIT margin of -10.04% in the TTM. This indicates ongoing challenges in achieving profitability and managing costs effectively.
Balance Sheet
35
Negative
The balance sheet shows a low debt-to-equity ratio of 0.096, suggesting limited leverage, which is a positive aspect. However, the return on equity is negative at -76.07%, indicating that the company is not generating returns on shareholders' equity. The equity ratio is relatively stable, but overall financial health is impacted by persistent losses.
Cash Flow
25
Negative
The cash flow statement reveals a negative operating cash flow, with a ratio of -2.34 in the TTM, indicating that the company is not generating sufficient cash from operations. Although there is a slight improvement in free cash flow growth of 14.52%, the overall cash flow situation remains challenging, with free cash flow to net income ratio at 1.02.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue43.53M58.84M43.88M39.68M10.00M3.41M
Gross Profit-40.84M13.60M1.29M-8.59M10.00M3.41M
EBITDA-636.92M-426.72M-307.63M-227.66M-175.12M-81.70M
Net Income-715.54M-463.66M-328.07M-239.48M-186.48M-87.01M
Balance Sheet
Total Assets1.40B1.45B653.70M701.29M610.35M298.58M
Cash, Cash Equivalents and Short-Term Investments659.84M594.35M391.56M549.91M516.56M262.13M
Total Debt82.37M108.49M50.67M51.01M11.48M15.66M
Total Liabilities352.58M413.82M190.26M215.48M67.41M504.87M
Stockholders Equity1.05B1.03B463.44M485.81M542.94M-206.29M
Cash Flow
Free Cash Flow-448.04M-372.87M-300.33M-120.88M-198.41M-52.13M
Operating Cash Flow-441.17M-359.17M-287.78M-83.52M-158.61M-45.40M
Investing Cash Flow259.83M260.06M-10.23M193.25M-271.74M-8.74M
Financing Cash Flow400.17M304.12M140.13M154.34M458.54M246.13M

Recursion Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price4.68
Price Trends
50DMA
5.00
Negative
100DMA
5.05
Negative
200DMA
5.18
Negative
Market Momentum
MACD
-0.09
Negative
RSI
46.76
Neutral
STOCH
31.61
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RXRX, the sentiment is Negative. The current price of 4.68 is above the 20-day moving average (MA) of 4.48, below the 50-day MA of 5.00, and below the 200-day MA of 5.18, indicating a bearish trend. The MACD of -0.09 indicates Negative momentum. The RSI at 46.76 is Neutral, neither overbought nor oversold. The STOCH value of 31.61 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for RXRX.

Recursion Pharmaceuticals Risk Analysis

Recursion Pharmaceuticals disclosed 107 risk factors in its most recent earnings report. Recursion Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Recursion Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
60
Neutral
$3.47B-78.36-28.17%129.21%80.35%
53
Neutral
$2.46B-30.66-37.18%42.57%60.03%
52
Neutral
$2.44B-2.45-91.06%-32.98%-18.46%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$1.48B-3.56-27.57%36.26%-158.98%
47
Neutral
$2.07B-4.25-16.45%
43
Neutral
$3.30B-16.88-34.78%-34.96%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RXRX
Recursion Pharmaceuticals
4.44
-1.59
-26.37%
AGIO
Agios Pharma
24.73
-10.69
-30.18%
GLPG
Galapagos
31.53
4.77
17.83%
ADPT
Adaptive Biotechnologies
16.50
10.11
158.22%
ARQT
Arcutis Biotherapeutics
27.78
12.79
85.32%
IRON
Disc Medicine
87.49
22.99
35.64%

Recursion Pharmaceuticals Corporate Events

Product-Related AnnouncementsBusiness Operations and Strategy
Recursion Pharmaceuticals Reports Positive TUPELO Trial Results
Positive
Dec 8, 2025

On December 8, 2025, Recursion Pharmaceuticals announced positive results from the Phase 1b/2 TUPELO trial of REC-4881, an investigational MEK1/2 inhibitor for familial adenomatous polyposis (FAP). The trial demonstrated rapid and durable reductions in polyp burden, with 75% of patients showing improvement after 12 weeks of treatment, and 82% maintaining reductions 12 weeks post-treatment. These findings are significant given the lack of approved therapies for FAP, a condition with a high risk of colorectal cancer. The results validate Recursion’s AI-driven approach and suggest REC-4881 could offer a non-surgical treatment option, potentially impacting the company’s market positioning and providing hope for patients with FAP.

Private Placements and FinancingRegulatory Filings and Compliance
Recursion Pharmaceuticals Registers Resale of 7 Million Shares
Neutral
Nov 26, 2025

On November 26, 2025, Recursion Pharmaceuticals filed a prospectus supplement to register for resale over 7 million shares of its Class A common stock issued to Tempus AI, Inc. as payment for annual license fees. This move, made under an exemption from registration, highlights Recursion’s strategic financial maneuvers to manage its equity and partnerships, potentially impacting its market positioning and stakeholder interests.

Executive/Board ChangesBusiness Operations and StrategyFinancial Disclosures
Recursion Pharmaceuticals Announces New CEO Appointment
Positive
Nov 5, 2025

Recursion Pharmaceuticals announced significant leadership changes effective January 1, 2026, with Najat Khan, Ph.D., appointed as the new Chief Executive Officer and President, while Christopher Gibson, Ph.D., transitions to Chair of the Board. This leadership transition is accompanied by a strong financial performance, with the company achieving over $500 million in milestone and upfront payments from partnerships, including a recent $30 million milestone from Roche and Genentech. The company continues to advance its internal and partnered programs, leveraging its AI-driven platform, Recursion OS, to drive innovation in drug discovery and development.

Product-Related AnnouncementsBusiness Operations and Strategy
Roche Exercises Option with Recursion Pharmaceuticals
Positive
Oct 29, 2025

On October 29, 2025, Recursion Pharmaceuticals announced that Roche exercised its option for the Microglia Map, a pioneering whole genome map of brain immune cells, under their collaboration agreement. As a result, Roche will pay Recursion an Acceptance Fee of $30 million, highlighting the significant impact of this collaboration on Recursion’s operations and industry positioning.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 09, 2025