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Arcutis Biotherapeutics (ARQT)
NASDAQ:ARQT
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Arcutis Biotherapeutics (ARQT) AI Stock Analysis

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ARQT

Arcutis Biotherapeutics

(NASDAQ:ARQT)

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Neutral 59 (OpenAI - 4o)
Rating:59Neutral
Price Target:
$26.00
▲(3.59% Upside)
Arcutis Biotherapeutics' overall score is driven by strong earnings call results and technical indicators, despite challenges in financial performance and valuation. The company's strategic initiatives and revenue growth are promising, but profitability and cash flow management remain areas for improvement.
Positive Factors
Strong Revenue Growth
The significant revenue growth indicates strong market demand and successful product adoption, which can drive long-term business expansion and financial stability.
Pipeline Expansion
Expanding the pipeline with new indications can enhance the company's competitive position and provide additional revenue streams, supporting sustained growth.
Strong Market Position
Capturing a significant market share demonstrates competitive strength and brand recognition, which are crucial for maintaining and expanding market leadership.
Negative Factors
Profitability Challenges
Despite revenue growth, ongoing profitability issues could hinder reinvestment in R&D and limit financial flexibility, affecting long-term sustainability.
Cash Flow Management
Negative cash flows indicate reliance on external financing, which can be risky if market conditions change, potentially impacting operational stability.
Dependency on Topical Steroids
High dependency on topical steroids suggests challenges in shifting market behavior, which could limit the adoption of innovative therapies and affect growth.

Arcutis Biotherapeutics (ARQT) vs. SPDR S&P 500 ETF (SPY)

Arcutis Biotherapeutics Business Overview & Revenue Model

Company DescriptionArcutis Biotherapeutics, Inc., a biopharmaceutical company, focuses on developing and commercializing treatments for dermatological diseases. Its lead product candidate is ARQ-151, a topical roflumilast cream that has completed Phase III clinical trials for the treatment of plaque psoriasis and atopic dermatitis. The company is also developing ARQ-154, a topical foam formulation of roflumilast for the treatment of seborrheic dermatitis and scalp psoriasis; ARQ-252, a selective topical janus kinase type 1 inhibitor for hand eczema and vitiligo; and ARQ-255, a topical formulation of ARQ-252 designed to reach deeper into the skin in order to treat alopecia areata. The company was formerly known as Arcutis, Inc. and changed its name to Arcutis Biotherapeutics, Inc. in October 2019. Arcutis Biotherapeutics, Inc. was incorporated in 2016 and is headquartered in Westlake Village, California.
How the Company Makes MoneyArcutis Biotherapeutics generates revenue primarily through the commercialization of its pharmaceutical products. The company earns money through direct sales of its approved therapies, which are marketed to healthcare providers and pharmacies. Additionally, Arcutis may engage in strategic partnerships and collaborations with larger pharmaceutical companies, which can provide upfront payments, milestone payments, and royalties on product sales. These partnerships may also involve co-development agreements, allowing Arcutis to share the costs and risks associated with bringing new therapies to market. Furthermore, the company may receive funding through grants or research agreements focused on advancing its product pipeline.

Arcutis Biotherapeutics Earnings Call Summary

Earnings Call Date:Oct 01, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Mar 03, 2026
Earnings Call Sentiment Positive
The earnings call for Arcutis Biotherapeutics highlighted strong revenue and prescription growth driven by the ZORYVE franchise and recent FDA approval. Despite seasonal factors expected to moderate growth and challenges in Medicare Part D coverage, the positive cash flow and strategic plans suggest a promising outlook.
Q2-2025 Updates
Positive Updates
Strong Revenue Growth
Arcutis reported net product revenues of $81.5 million in Q2 2025, representing a 28% quarter-on-quarter growth and a 164% increase compared to the same quarter in 2024.
FDA Approval for ZORYVE Foam
Received FDA approval for ZORYVE foam 0.3% for the treatment of plaque psoriasis of the scalp and body, marking the fifth FDA approval for ZORYVE in the last 3 years.
Increased Prescription Volume
ZORYVE prescription volume reached a record high with nearly 200,000 total prescriptions in the quarter, reflecting a year-over-year volume increase of 117% and a quarter-over-quarter increase of 13%.
Positive Cash Flow from Operations
The company reported a positive net cash flow from operating activities of $325,000 in Q2 2025.
Negative Updates
Seasonality Impact on Growth
Anticipated moderation in sequential growth rate in Q3 2025 due to seasonality factors such as summer vacations and reduced flaring of inflammatory skin conditions.
Medicare Part D Coverage Challenges
Progress with Medicare Part D plans is slow due to financial disruptions from the Inflation Reduction Act, leading to a more protracted process for coverage decisions.
Halted Development of ARQ-255
The company decided to halt further development of ARQ-255 following disappointing results from the Phase Ib trial.
Company Guidance
In the Arcutis Biotherapeutics 2025 Second Quarter Financial Results Conference Call, the company reported strong financial performance and strategic progress. Net product revenues reached $81.5 million, marking a 28% increase from the previous quarter and a 164% growth compared to the second quarter of 2024. This growth was driven by increased demand for ZORYVE, with prescriptions reaching 16,000 weekly scripts and a total of nearly 200,000 prescriptions in the quarter, reflecting a 13% quarter-over-quarter increase and a 117% year-over-year increase. The company's gross-to-net rates remained stable, supported by strong insurance coverage. Arcutis also highlighted its strategic focus on expanding ZORYVE's indications, with a fifth FDA approval for ZORYVE foam 0.3% for plaque psoriasis of the scalp and body in May. The company is pursuing further label expansions, particularly in pediatric atopic dermatitis, with an upcoming PDUFA date in October for ZORYVE cream 0.05% for children aged 2 to 5. Arcutis is on track for cash flow breakeven in 2026, supported by disciplined capital allocation and a strategic focus on leveraging its development and commercialization capabilities.

Arcutis Biotherapeutics Financial Statement Overview

Summary
Arcutis Biotherapeutics shows strong revenue growth but struggles with profitability, as evidenced by negative net profit and EBIT margins. The low debt-to-equity ratio is a positive, but negative cash flows and returns on equity highlight the need for strategic improvements.
Income Statement
45
Neutral
Arcutis Biotherapeutics shows a strong gross profit margin of approximately 90% TTM, indicating efficient cost management relative to revenue. However, the company is struggling with profitability, as evidenced by negative net profit and EBIT margins. Despite a significant revenue growth rate of 20.67% TTM, the company remains unprofitable, which is common in the biotechnology industry during the development phase.
Balance Sheet
50
Neutral
The balance sheet reflects a low debt-to-equity ratio of 0.04 TTM, suggesting conservative leverage. However, the return on equity is negative, indicating that the company is not generating profit from its equity base. The equity ratio is relatively stable, but the company needs to improve its profitability to enhance shareholder value.
Cash Flow
40
Negative
The cash flow statement reveals challenges in cash generation, with negative operating and free cash flows. The free cash flow to net income ratio is above 1, indicating that cash outflows are higher than net losses, which might be due to significant R&D investments typical in biotech firms. The company needs to improve its cash flow management to sustain operations without relying heavily on external financing.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue317.93M196.54M59.61M3.69M0.000.00
Gross Profit286.02M177.41M54.62M2.93M-763.00K-455.00K
EBITDA-23.95M-109.63M-227.43M-294.55M-205.59M-135.22M
Net Income-44.32M-140.04M-262.14M-311.46M-206.36M-135.68M
Balance Sheet
Total Assets370.98M348.89M341.37M449.27M408.15M298.27M
Cash, Cash Equivalents and Short-Term Investments191.07M227.96M271.86M409.59M387.06M284.44M
Total Debt6.28M110.58M205.92M202.54M77.56M4.96M
Total Liabilities212.90M191.35M252.70M239.69M110.47M27.65M
Stockholders Equity158.07M157.54M88.67M209.58M297.68M270.62M
Cash Flow
Free Cash Flow-38.24M-112.30M-247.49M-281.00M-175.62M-113.35M
Operating Cash Flow-32.56M-112.16M-247.06M-257.71M-174.63M-113.03M
Investing Cash Flow38.80M28.82M180.23M-87.20M-75.95M-181.82M
Financing Cash Flow-94.16M66.20M101.32M301.80M281.95M298.14M

Arcutis Biotherapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price25.10
Price Trends
50DMA
19.63
Positive
100DMA
17.23
Positive
200DMA
15.64
Positive
Market Momentum
MACD
1.56
Negative
RSI
67.46
Neutral
STOCH
65.47
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ARQT, the sentiment is Positive. The current price of 25.1 is above the 20-day moving average (MA) of 22.23, above the 50-day MA of 19.63, and above the 200-day MA of 15.64, indicating a bullish trend. The MACD of 1.56 indicates Negative momentum. The RSI at 67.46 is Neutral, neither overbought nor oversold. The STOCH value of 65.47 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ARQT.

Arcutis Biotherapeutics Risk Analysis

Arcutis Biotherapeutics disclosed 73 risk factors in its most recent earnings report. Arcutis Biotherapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Arcutis Biotherapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
83
Outperform
$1.81B9.7425.93%21.13%50.86%
60
Neutral
$3.04B-28.35%182.44%47.21%
59
Neutral
$2.94B-28.17%129.21%80.35%
54
Neutral
$3.05B-410.78%114.22%77.02%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
43
Neutral
$3.30B-26.36%-22.19%
41
Neutral
$2.16B-86.34%30.14%-10.08%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ARQT
Arcutis Biotherapeutics
25.10
14.70
141.35%
TVTX
Travere Therapeutics
33.30
15.64
88.56%
IRON
Disc Medicine
87.00
23.67
37.38%
HRMY
Harmony Biosciences Holdings
30.94
-3.97
-11.37%
TARS
Tarsus Pharmaceuticals
68.09
21.30
45.52%
RXRX
Recursion Pharmaceuticals
4.62
-2.31
-33.33%

Arcutis Biotherapeutics Corporate Events

Arcutis Biotherapeutics Reports Strong Q3 Earnings Call
Oct 29, 2025

Arcutis Biotherapeutics Inc. recently held an earnings call that reflected a strong positive momentum for the company. The call highlighted significant revenue growth, a shift to positive net income, and an accelerated timeline for achieving cash flow breakeven. Despite challenges in changing market behavior away from topical steroids, Arcutis’s strategic initiatives and pipeline expansions position it well for future growth.

Arcutis Biotherapeutics’ Earnings Call: Growth Amid Challenges
Aug 8, 2025

Arcutis Biotherapeutics Inc’s recent earnings call painted a picture of robust growth and strategic advancements, tempered by certain challenges. The company celebrated significant revenue growth and multiple FDA approvals for its flagship product, ZORYVE, indicating strong commercial execution and a promising pipeline. However, the overall sentiment was moderated by the halted development of ARQ-255 and difficulties in securing Medicare Part D coverage.

Arcutis Biotherapeutics Reports Strong Q2 2025 Growth
Aug 7, 2025

Arcutis Biotherapeutics, Inc. is a commercial-stage biopharmaceutical company specializing in the development of innovative treatments for immune-mediated dermatological conditions. The company is known for its focus on creating advanced topical therapies for inflammatory skin diseases.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 29, 2025