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Qiagen NV (QGEN)
NYSE:QGEN

Qiagen (QGEN) AI Stock Analysis

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QGEN

Qiagen

(NYSE:QGEN)

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Outperform 72 (OpenAI - 5.2)
Rating:72Outperform
Price Target:
$57.00
▲(14.46% Upside)
Action:ReiteratedDate:02/07/26
The score is driven primarily by improved 2025 financial performance and a supportive outlook for continued profitable growth in 2026, tempered by historical earnings/cash-flow variability and near-term operational headwinds. Technicals are constructive but not strongly bullish, while valuation is helped by the high dividend yield despite a mid-range P/E.
Positive Factors
High Profitability and Margins
Sustained high gross and net margins indicate strong pricing power and efficient operations across consumables and assays. Durable margin structure supports reinvestment in R&D, funds shareholder returns, and provides a buffer against cyclical revenue swings over the medium term.
Strengthening Product Portfolio & Growth Areas
Consistent growth in diagnostics and digital PCR, plus the Parse Biosciences acquisition, expands exposure to high-growth single-cell and AI-driven genomics. This diversifies revenue toward structural, consumable-heavy markets with recurring demand and higher long-term TAM.
Manageable Leverage and Capital Structure
Moderate leverage and solid ROE provide financial flexibility for M&A, R&D funding, and shareholder returns without overburdening cash flow. A healthy capital structure supports strategic investments and resilience through industry cycles over the next several quarters.
Negative Factors
Slowing Revenue and Declining Free Cash Flow
Slowing top-line momentum and negative FCF growth erode internal funding for innovation and could increase reliance on buybacks to sustain EPS. If persistent, this weakens the company’s ability to fund organic expansion and meet its 7% multi-year growth ambitions.
Regional Exposure: Asia Pacific / China Weakness
A mid‑teen decline in China represents a meaningful loss in a large growth market and signals execution or demand issues. Prolonged weakness in APAC could materially slow consolidated growth and necessitate targeted commercial or regulatory strategies to restore momentum.
Currency and Tariff Headwinds
Persistent FX volatility and tariff exposure can structurally compress margins and force pricing or cost adjustments. Over months, these pressures complicate margin guidance and may require sustainable cost or supply-chain changes that affect competitiveness and profitability.

Qiagen (QGEN) vs. SPDR S&P 500 ETF (SPY)

Qiagen Business Overview & Revenue Model

Company DescriptionQIAGEN N.V. offers sample to insight solutions that transform biological materials into molecular insights worldwide. The company provides primary sample technology consumables, such as nucleic stabilization and purification kits for primary sample materials, manual and automated processing for genotyping, gene expression, and viral and bacterial analysis, as well as silica membranes and magnetic bead technologies; secondary sample technology consumables, including kits and components for purification of nucleic acids from secondary sample materials; and instruments for nucleic acid purification and accessories. It also provides interferon-gamma release assay for TB testing, and assays for post-transplant testing and viral load monitoring; assays for prenatal testing and detection of sexually transmitted diseases and HPV, as well as assays for analysis of genomic variants, such as mutations, insertions, deletions, and fusions; and sample to insight instruments, including one-step molecular analysis of hard-to-diagnose syndromes, and integrated PCR testing. In addition, it offers PCR consumables, such as quantitative PCR, reverse transcription, and combinations kits for analysis of gene expression, genotyping, and gene regulation instruments and technologies; human ID and forensics assay consumables, including STR assays for human ID, and assays for food contamination; PCR instruments consist of digital PCR solutions; and developed and configured OEM consumables. Further, the company provides predefined and custom NGS gene panels, library prep kits and components, and whole genome amplification; QIAGEN consumables and instruments, as well as bioinformatics solutions; and custom laboratory and genomic services. It serves molecular diagnostics, academia, pharmaceutical, and applied testing customers. It has a strategic alliance agreement with Sysmex Corporation and OncXerna Therapeutics, as well as an agreement with Mirati. The company was founded in 1986 and is headquartered in Venlo, the Netherlands.
How the Company Makes MoneyQiagen generates revenue primarily through the sale of its products and services across several key segments. The company's revenue model is based on the sale of consumables, instruments, and services, with consumables being the largest revenue contributor, driven by the ongoing demand for molecular testing and personalized medicine. Key revenue streams include the sale of sample preparation kits and molecular assays for use in research and clinical settings. Additionally, Qiagen benefits from strategic partnerships with healthcare providers, pharmaceutical companies, and research institutions, which enhance its market reach and allow for collaborative product development. The growing trend towards precision medicine and increased investment in genomic research further support Qiagen's earnings potential.

Qiagen Key Performance Indicators (KPIs)

Any
Any
Revenue by Geography
Revenue by Geography
Chart Insights
Data provided by:The Fly

Qiagen Earnings Call Summary

Earnings Call Date:Feb 04, 2026
(Q4-2025)
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% Change Since: |
Next Earnings Date:May 04, 2026
Earnings Call Sentiment Positive
The call presents a broadly positive operational and financial picture: QIAGEN beat Q4 and full-year outlooks, delivered margin expansion and strong free cash flow, progressed multiple growth pillars (Sample Technologies, QuantiFERON, QIAstat, QIAcuity, QDI), completed strategic acquisitions (Parse, Genoox) and set 2026 guidance for continued profitable growth. Notable near-term challenges include declines in PCR/NGS consumables, regional softness (U.S. and China), tariff and FX headwinds, and short-term dilution from Parse and discontinued product lines that weigh on Q1/first-half 2026. Management expects improvement and acceleration into H2 2026 driven by new product launches and strengthened growth pillars.
Q4-2025 Updates
Positive Updates
Q4 Results Above Outlook
Net sales of $540M in Q4 2025, up 1% at constant exchange rates (CER) and ahead of outlook (which assumed flat sales). Adjusted diluted EPS was $0.62 at CER vs. outlook of about $0.60.
Full-Year 2025 Performance
Full-year net sales of $2.09B, up 5% CER (at the high end of the 4%–5% outlook). Adjusted diluted EPS was $2.40 at CER (reported $2.38), above guidance and achieved after two upward revisions during the year.
Growth Pillars Momentum
Combined sales from Sample Technologies, QuantiFERON, QIAstat, QIAcuity and QIAGEN Digital Insights reached $1.49B in 2025, up 8% CER year-over-year; management remains on track for at least $2B from these pillars by 2028.
Sample Technologies Strength & Strategic Expansion
Sample Technologies grew mid-single-digits in Q4 (+5% CER) and 2% CER for full year; installed base ~31,400 placements; liquid biopsy sample prep grew >30%; completed Parse Biosciences acquisition (adds single-cell capability).
QuantiFERON Growth and Product Innovation
QuantiFERON grew 5% CER in Q4 and 10% CER for the full year 2025; next-gen TB assay increases throughput up to ~75% and reduces turnaround time ~25%; U.S. launch planned in 2026 to capture underpenetrated latent TB market.
QIAstat Strong Adoption
QIAstat grew 15% CER in Q4 and 24% CER for full year 2025 with cumulative installed base >5,200 instruments; menu expansion (including blood culture panels) supports consumable-led growth and a $160M sales target for 2026.
QIAcuity Consumables and Installed Base Growth
Digital PCR consumables delivered double-digit growth in 2025 and cumulative QIAcuity placements exceeded 3,200 systems; over 100 instruments placed per quarter in Q4 despite a cautious capital spending environment.
Bioinformatics (QDI) Progress
QIAGEN Digital Insights delivered continued growth supported by the Genoox integration and AI-enabled workflows; company plans ~14 AI-enabled software solutions over next 2 years and targets ~$125M for QDI in 2026.
Margin Expansion and Profitability
Adjusted operating income margin expanded 80 basis points to 29.5% in 2025. Excluding tariffs and adverse FX headwinds (~120 bps), margin improvement was roughly 200 bps, supporting confidence toward the 31%+ midterm target.
Strong Cash Generation and Capital Returns
Operating cash flow of $654M and free cash flow of $453M in 2025; returned over $1.1B to shareholders since 2024, completed $500M synthetic share repurchase in Jan 2026; pro forma net leverage ~1.3x net debt / adjusted EBITDA.
2026 Financial Outlook
Full-year 2026 guidance: at least 5% CER sales growth and adjusted EPS of at least $2.50 at CER. First-quarter 2026 guidance: at least 1% CER sales growth and EPS of at least $0.54 at CER; management expects growth acceleration in H2 2026.
Negative Updates
PCR Product Group Decline
PCR product group sales declined 9% CER in Q4 2025; while QIAcuity consumables grew, sales of other PCR consumables fell due to a cautious funding environment and lower OEM contributions versus 2024.
Pressure on NGS Consumables
Genomics / NGS product group under pressure in 2025 with NGS consumables showing weakness despite double-digit growth in the QDI bioinformatics segment.
Regional Softness in Americas and China
Americas sales declined 1% CER in Q4 (U.S. flat at CER, partly affected by the U.S. government shutdown). China sales declined in the low teens CER in Q4; China represents ~4% of total sales and is expected to remain low single-digit to negative/flat.
Tariffs, Currency and Acquisition Headwinds
Approximately 120 basis points of tariff and adverse currency headwinds in 2025; management expects combined headwinds of about 160 basis points in 2026 (including Parse acquisition dilution, tariffs and FX).
Dilutive Impact from Parse Acquisition
Parse acquisition carries near-term dilutive effects: roughly 100 basis points of margin dilution cited for 2026 and an estimated $0.02 EPS dilution in Q1 2026.
Near-Term First-Quarter Headwinds
Q1 2026 faces temporary headwinds: discontinuation of NeuMoDx and Dialunox (~$10M or ~2 percentage points impact), cautious life-science customer spending (~$10M or ~2 ppts), and a strong Q1 2025 comp in QuantiFERON (~$6–7M headwind).
Sluggish Capital Spending Environment
Slower capital spending in research and academia weighed on instrument placements (notably in digital PCR instrumentation), delaying some expected instrument-driven revenue despite strong consumables growth.
Free Cash Flow Impacted by Investments
Free cash flow ($453M) was below operating cash flow due to higher capital expenditures related primarily to IT investments (SAP upgrade) and cash payments (~$54M) for efficiency initiatives, reducing near-term cash flexibility.
Competitive and Pricing Pressures on QuantiFERON
Management noted increased competition in the latent TB market and indicated willingness to use pricing flexibility or longer-term contract concessions to secure volume, which could pressure margins/pricing in some deals.
Company Guidance
QIAGEN guided 2026 to at least 5% sales growth at constant exchange rates (CER) and adjusted diluted EPS of at least $2.50 at CER, while expecting the adjusted operating income margin to remain about 29.5% (despite ~160 basis points of headwinds from the Parse acquisition, tariffs and FX); currency is expected to be a ~1‑point tailwind to full‑year sales (neutral to EPS) and ~2–3 points tailwind to Q1 sales. For Q1 the company expects net sales growth of at least 1% CER versus Q1‑25 ($483 million) and adjusted EPS of at least $0.54 at CER (vs $0.55 a year ago), noting Q1 headwinds of roughly $10M from the discontinuation of NeuMoDx/Dialunox (~2 percentage points), ~$10M from cautious life‑science spending (~2 points), and a low‑single‑digit QuantiFERON comparison (≈$6–7M, ~1 point); Parse will dilute Q1 EPS by ~$0.02 and U.S. tariffs by ~ $0.02. Management expects H1 growth of roughly 2–3% CER with an H2 acceleration to reach the full‑year target, a normalized run rate near 6% CER after roll‑offs, a currency‑neutral EPS impact, and continued focus on growth pillars (targeting ~9% CER growth in 2026 with Sample Technologies ≈ $720M, QuantiFERON ≈ $535M, QIAstat ≈ $160M, QIAcuity ≈ $100M and QDI ≈ $125M); the company completed a $500M share repurchase in January and shows pro‑forma leverage of ~1.3x net debt/adjusted EBITDA.

Qiagen Financial Statement Overview

Summary
Financials show a meaningful 2025 rebound with strong profitability (net margin ~20%, operating margin ~25%) and improved gross margin (~62%). Leverage is manageable (debt-to-equity ~0.44) and cash generation is solid (2025 OCF ~$654M, FCF ~$453M), but multi-year volatility (notably the 2024 dip) and uneven cash conversion/FCF trend keep the score below top-tier.
Income Statement
78
Positive
Profitability is strong and has rebounded meaningfully: 2025 revenue rose to ~$2.09B (about +6% vs. 2024) while net margin expanded sharply to ~20% (vs. ~4% in 2024), with operating margin back near ~25% (vs. ~8% in 2024). Gross margin also improved to ~62% in 2025 from ~49% in 2024, closer to the company’s historically higher levels (2020–2023). The key weakness is volatility in earnings power and margins across years (notably the 2024 dip), and reported revenue growth appears inconsistent over time (including down years).
Balance Sheet
74
Positive
Leverage looks manageable: debt-to-equity sits around ~0.44 in 2025 (improved from ~0.54 in 2022 and ~0.63–0.70 in 2020–2021), supported by a sizable equity base (~$3.78B) against ~$1.65B of debt. Returns on equity improved to ~11% in 2025 after a weak 2024 (~2%), indicating better profitability on the capital base. The main watch items are the upward move in absolute debt from 2024 to 2025 and the historical variability in returns, which can pressure balance-sheet flexibility if performance softens again.
Cash Flow
70
Positive
Cash generation is solid, with 2025 operating cash flow of ~$654M and free cash flow of ~$453M, and operating cash flow exceeding net income (coverage ~1.28x), supporting earnings quality. Free cash flow also covers a meaningful share of profits (about ~69% of net income in 2025). Offsetting this, free cash flow declined in 2025 (negative growth vs. 2024) and cash conversion has been uneven historically (including a notably weak operating cash flow coverage in 2021–2023), suggesting potential working-capital or investment-driven volatility.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue2.09B1.98B1.97B2.14B2.25B
Gross Profit1.29B967.35M1.23B1.38B1.45B
EBITDA717.27M368.26M688.55M779.36M895.24M
Net Income424.88M83.59M341.30M423.21M512.60M
Balance Sheet
Total Assets6.30B5.69B6.12B6.29B6.15B
Cash, Cash Equivalents and Short-Term Investments1.10B1.15B1.06B1.42B1.07B
Total Debt1.65B1.61B1.69B2.03B2.12B
Total Liabilities2.52B2.12B2.31B2.82B3.05B
Stockholders Equity3.78B3.57B3.81B3.47B3.10B
Cash Flow
Free Cash Flow453.28M506.38M296.65M565.93M432.47M
Operating Cash Flow654.33M673.55M459.45M715.26M639.00M
Investing Cash Flow-305.28M-249.23M-87.66M-726.76M-202.43M
Financing Cash Flow-178.98M-422.90M-433.83M-125.80M-150.37M

Qiagen Technical Analysis

Technical Analysis Sentiment
Positive
Last Price49.80
Price Trends
50DMA
49.24
Positive
100DMA
47.88
Positive
200DMA
47.41
Positive
Market Momentum
MACD
-0.43
Positive
RSI
50.04
Neutral
STOCH
52.96
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For QGEN, the sentiment is Positive. The current price of 49.8 is below the 20-day moving average (MA) of 50.20, above the 50-day MA of 49.24, and above the 200-day MA of 47.41, indicating a neutral trend. The MACD of -0.43 indicates Positive momentum. The RSI at 50.04 is Neutral, neither overbought nor oversold. The STOCH value of 52.96 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for QGEN.

Qiagen Risk Analysis

Qiagen disclosed 38 risk factors in its most recent earnings report. Qiagen reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Qiagen Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
72
Outperform
$10.10B24.3711.57%3.31%5.32%336.29%
70
Outperform
$50.70B48.6866.20%8.39%21.44%
64
Neutral
$10.69B47.363.22%0.29%3.37%-18.80%
61
Neutral
$188.93B29.3813.02%0.30%3.91%7.09%
59
Neutral
$20.32B24.3233.36%-2.39%
59
Neutral
$29.57B22.1821.64%3.85%-4.74%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
QGEN
Qiagen
48.83
10.74
28.21%
IDXX
Idexx Laboratories
636.70
199.55
45.65%
ILMN
Illumina
132.89
48.69
57.83%
RVTY
Revvity
95.59
-14.49
-13.16%
TMO
Thermo Fisher
508.58
-13.21
-2.53%
IQV
IQVIA Holdings
174.27
-10.58
-5.72%

Qiagen Corporate Events

Qiagen Tops 2025 Guidance and Sets Ambitious 2026 Growth Targets
Feb 6, 2026

On February 4, 2026, Qiagen reported unaudited results for the fourth quarter and full year ended December 31, 2025, posting Q4 net sales of $540 million, up 4% year on year (1% at constant exchange rates), and diluted EPS of $0.49, with adjusted diluted EPS of $0.62 at constant exchange rates beating its guidance. For 2025, net sales rose 6% to $2.09 billion (5% at constant exchange rates), at the top end of its upgraded outlook, while adjusted diluted EPS reached $2.40 at constant exchange rates, ahead of forecasts, underpinned by 8% constant-currency growth in its strategic growth pillars to $1.49 billion, an 80-basis-point improvement in adjusted operating margin to 29.5% despite tariffs and FX headwinds, and the first contribution from the Parse acquisition alongside headwinds from discontinued NeuMoDx and Dialunox products. Management highlighted disciplined execution in a challenging macro environment, including the impact of the 2025 U.S. government shutdown, continued cost-efficiency and digitization efforts, and an accelerated capital allocation program that returned more than $1.1 billion to shareholders and added Genoox and Parse as bolt-on deals, while setting a 2026 outlook for at least 5% constant-currency sales growth driven by roughly 9% growth in its core pillars and adjusted EPS of at least $2.50, signaling confidence in sustained profitable expansion and ongoing investment capacity.

The most recent analyst rating on (QGEN) stock is a Buy with a $55.00 price target. To see the full list of analyst forecasts on Qiagen stock, see the QGEN Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 07, 2026