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IQVIA Holdings Inc (IQV)
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IQVIA Holdings (IQV) AI Stock Analysis

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IQV

IQVIA Holdings

(NYSE:IQV)

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Outperform 77 (OpenAI - 4o)
Rating:77Outperform
Price Target:
$248.00
▲(14.57% Upside)
IQVIA's strong financial performance and positive earnings call sentiment are the most significant factors driving the overall score. The company's robust cash flow and strategic focus on AI and technology advancements suggest potential for future growth. However, the high P/E ratio and absence of a dividend yield weigh on the valuation, and technical indicators suggest caution due to nearing overbought conditions.
Positive Factors
Revenue Growth
Consistent revenue growth indicates strong market demand and effective business strategies, supporting long-term financial stability.
AI and Technology Advancements
Investing in AI enhances operational efficiency and competitive positioning, potentially leading to improved margins and innovation.
Cash Flow Generation
Strong cash flow generation provides financial flexibility for investments and debt reduction, supporting sustainable growth.
Negative Factors
R&D Solutions Revenue Growth
Slower growth in R&D Solutions may indicate challenges in capturing market share, potentially affecting future revenue streams.
Phase I and Mega Trials Delays
Delays in major trials can impact revenue timelines and client trust, posing risks to long-term project pipelines.
Margin Headwinds
Margin pressures from currency impacts and lower-margin segments could affect profitability, challenging cost management efforts.

IQVIA Holdings (IQV) vs. SPDR S&P 500 ETF (SPY)

IQVIA Holdings Business Overview & Revenue Model

Company DescriptionIQVIA Holdings Inc. provides advanced analytics, technology solutions, and clinical research services to the life sciences industry in the Americas, Europe, Africa, and the Asia-Pacific. It operates through three segments: Technology & Analytics Solutions, Research & Development Solutions, and Contract Sales & Medical Solutions. The Technology & Analytics Solutions segment offers a range of cloud-based applications and related implementation services; real world solutions that enable life sciences and provider customers to generate and disseminate evidence, which informs health care decision making and improves patients' outcomes; and strategic and implementation consulting services, such as advanced analytics and commercial processes outsourcing services. This segment also provides country level performance metrics related to sales of pharmaceutical products, prescribing trends, medical treatment, and promotional activity across various channels, including retail, hospital, and mail order; and measurement of sales or prescribing activity at the regional, zip code, and individual prescriber level. The Research & Development Solutions segment offers project management and clinical monitoring; clinical trial support; virtual trials; and strategic planning and design services, as well as central laboratory, genomic, bioanalytical, ADME, discovery, and vaccine and biomarker laboratory services. The Contract Sales & Medical Solutions segment provides health care provider and patient engagement services, and scientific strategy and medical affairs services. It serves pharmaceutical, biotechnology, device and diagnostic, and consumer health companies. The company has a strategic collaboration with HealthCore, Inc. The company was formerly known as Quintiles IMS Holdings, Inc. and changed its name to IQVIA Holdings Inc. in November 2017. IQVIA Holdings Inc. was founded in 1982 and is headquartered in Durham, North Carolina.
How the Company Makes MoneyIQVIA generates revenue through a combination of service-based contracts and subscription-based solutions. Its key revenue streams include fees from clinical trial management and support services, which involve designing and conducting clinical trials for pharmaceutical and biotechnology companies. Additionally, IQVIA earns revenue from its technology solutions, including data analytics and software platforms that offer insights into healthcare trends and patient populations. Significant partnerships with pharmaceutical companies and healthcare organizations enhance its credibility and market reach, contributing to steady revenue growth. Furthermore, IQVIA's ability to provide integrated solutions across the drug development lifecycle allows it to capture a larger share of the market, driving further earnings.

IQVIA Holdings Key Performance Indicators (KPIs)

Any
Any
Revenue by Geography
Revenue by Geography
Breaks down revenue across different regions, revealing where the company is strongest and where it may face risk or growth potential due to local economic conditions or market share shifts.
Chart InsightsIQVIA's Americas revenue shows a steady upward trend, with a notable surge in late 2023, reflecting strong market demand. Meanwhile, Europe and Africa have experienced significant growth since mid-2024, likely driven by strategic AI and TAS initiatives. However, APAC's growth has been more volatile, possibly due to regional market uncertainties. The latest earnings call highlights record revenue and robust performance in TAS, but also notes challenges like market uncertainty and pricing pressures, which could impact future growth, particularly in the R&DS segment.
Data provided by:Main Street Data

IQVIA Holdings Earnings Call Summary

Earnings Call Date:Oct 28, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 18, 2026
Earnings Call Sentiment Positive
The earnings call conveyed a generally positive sentiment with strong financial performance, record-high free cash flow, and significant growth in net bookings and backlog. However, there were some challenges, particularly in the R&D Solutions segment and delays in mega trials. The company's focus on AI and technology advancements points to optimism for future efficiencies and growth.
Q3-2025 Updates
Positive Updates
Record High Free Cash Flow
IQVIA reported the highest quarterly free cash flow ever, driven by disciplined working capital management and improved industry conditions.
Strong Net Bookings and Backlog
Net bookings for the quarter totaled $2.6 billion, with a net book-to-bill ratio of 1.15x. The backlog reached a new record of $32.4 billion, up 4.1% from the previous year.
Solid Revenue Growth
Third quarter revenue was $4.1 billion, representing a year-over-year growth of 5.2% on a reported basis and 3.9% at constant currency.
Impressive Demand Metrics
EBP funding momentum reached $18 billion in Q3, with high single-digit RFP flow growth sequentially, and 20% growth year-over-year.
AI and Technology Advancements
IQVIA is developing 90 AI agents covering 25 use cases, with plans to develop 500 by 2027 to improve margins and operational efficiency.
Negative Updates
Limited Revenue Growth in R&D Solutions Segment
R&D Solutions revenue grew only 3.4% at constant currency, partially due to a step-down in COVID-related revenues.
Phase I and Mega Trials Delays
The mega trials mentioned earlier in the year have not resumed and are not expected to contribute to Q4 revenue.
Currency and Mix Impact on Margins
There were margin headwinds due to more pass-throughs from FX tailwinds and a stronger contribution from lower-margin CSMS.
Company Guidance
During the IQVIA Third Quarter 2025 Earnings Conference Call, the company delivered strong financial results, with revenue reaching $4.1 billion, marking a 5.2% growth on a reported basis and 3.9% at constant currency. They reported a net book-to-bill ratio of 1.15x, with net bookings totaling $2.6 billion, reflecting a 13% year-over-year growth. The company's qualified pipeline grew 6% compared to the previous year, and a backlog reached a record $32.4 billion, up 4.1%. The Technology & Analytics Solutions (TAS) segment reported revenue of $1.631 billion, with a 5% increase reported. The R&D Solutions segment had revenue of $2.26 billion, growing 4.5% on a reported basis. The Contract Sales & Medical Solutions (CSMS) segment saw a revenue increase of 16.1% reported. The company maintained its full-year 2025 guidance, expecting revenue between $16.150 billion and $16.250 billion, and projected adjusted diluted EPS between $11.85 and $11.95. The call highlighted ongoing strength in drug launches and the increasing use of AI in operations, with 90 AI agents in development covering 25 use cases.

IQVIA Holdings Financial Statement Overview

Summary
IQVIA Holdings exhibits strong financial performance with consistent revenue growth and improved profitability margins. The significant reduction in leverage enhances financial stability, while robust cash flow generation supports operational flexibility. However, attention to cost management and maintaining liquidity is crucial for sustaining growth.
Income Statement
85
Very Positive
IQVIA Holdings demonstrates strong revenue growth with a TTM (Trailing-Twelve-Months) revenue increase of 1.3% and consistent annual growth. The gross profit margin remains stable around 34%, while the net profit margin shows improvement, reaching 8.1% in the TTM period. EBIT and EBITDA margins are healthy, indicating efficient operations. However, the slight decline in gross profit margin over time suggests potential cost pressures.
Balance Sheet
70
Positive
The company's debt-to-equity ratio has significantly improved in the TTM period, dropping to 0.39 from over 2 in previous years, indicating reduced leverage and financial risk. Return on equity remains strong at 21.4%, reflecting effective use of equity to generate profits. However, the equity ratio is relatively low, suggesting a higher reliance on debt financing historically.
Cash Flow
78
Positive
IQVIA Holdings shows robust free cash flow growth of 31.3% in the TTM period, indicating strong cash generation capabilities. The operating cash flow to net income ratio is stable, and the free cash flow to net income ratio is high at 94.2%, reflecting efficient cash conversion. However, the operating cash flow coverage ratio has decreased slightly, which could indicate potential liquidity constraints.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue15.90B15.40B14.98B14.41B13.87B11.36B
Gross Profit5.37B5.38B5.24B5.03B4.64B3.86B
EBITDA3.44B3.45B3.26B2.91B2.77B2.08B
Net Income1.28B1.37B1.36B1.09B966.00M279.00M
Balance Sheet
Total Assets28.73B26.90B26.68B25.34B24.69B24.56B
Cash, Cash Equivalents and Short-Term Investments1.97B1.84B1.50B1.31B1.48B1.90B
Total Debt15.19B14.16B13.90B13.01B12.44B12.90B
Total Liabilities22.44B20.83B20.57B19.57B18.65B18.28B
Stockholders Equity6.16B6.07B6.11B5.76B6.04B6.00B
Cash Flow
Free Cash Flow2.64B2.11B1.50B1.59B2.30B1.34B
Operating Cash Flow2.80B2.72B2.15B2.26B2.94B1.96B
Investing Cash Flow-1.51B-1.44B-1.60B-2.01B-2.10B-796.00M
Financing Cash Flow-1.06B-878.00M-382.00M-329.00M-1.24B-217.00M

IQVIA Holdings Technical Analysis

Technical Analysis Sentiment
Positive
Last Price216.46
Price Trends
50DMA
197.07
Positive
100DMA
185.01
Positive
200DMA
178.15
Positive
Market Momentum
MACD
6.58
Positive
RSI
64.17
Neutral
STOCH
57.06
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For IQV, the sentiment is Positive. The current price of 216.46 is above the 20-day moving average (MA) of 210.25, above the 50-day MA of 197.07, and above the 200-day MA of 178.15, indicating a bullish trend. The MACD of 6.58 indicates Positive momentum. The RSI at 64.17 is Neutral, neither overbought nor oversold. The STOCH value of 57.06 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for IQV.

IQVIA Holdings Risk Analysis

IQVIA Holdings disclosed 51 risk factors in its most recent earnings report. IQVIA Holdings reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

IQVIA Holdings Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
$16.35B40.5973.70%13.88%23.92%
$36.86B29.7219.55%3.85%-4.74%
$151.90B44.046.84%0.57%2.22%-7.60%
$210.04B32.2713.16%0.30%3.22%8.26%
$19.57B20.6513.69%1.79%13.74%14.87%
$13.36B23.236.27%-2.46%-17.89%
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IQV
IQVIA Holdings
216.46
7.30
3.49%
DHR
Danaher
215.38
-30.89
-12.54%
ICLR
Icon
171.82
-48.58
-22.04%
DGX
Quest Diagnostics
175.95
23.54
15.45%
TMO
Thermo Fisher
567.39
11.43
2.06%
MEDP
Medpace Holdings
584.91
265.35
83.04%

IQVIA Holdings Corporate Events

IQVIA Holdings Reports Strong Q3 2025 Results
Oct 29, 2025

IQVIA Holdings Inc. is a global leader in providing clinical research services, commercial insights, and healthcare intelligence to the life sciences and healthcare industries, leveraging advanced analytics and AI technologies. In its third-quarter 2025 earnings report, IQVIA announced a revenue increase of 5.2% year-over-year, reaching $4.1 billion, with a GAAP net income of $331 million and an adjusted EBITDA of $949 million. The company also reported a significant free cash flow increase of 35% year-over-year, amounting to $772 million. Key financial highlights include a robust performance in its Research & Development Solutions segment, with quarterly bookings of $2.6 billion and a contracted backlog of $32.4 billion, indicating strong future revenue potential. Additionally, the Technology & Analytics Solutions and Contract Sales & Medical Solutions segments also showed solid growth. Looking forward, IQVIA remains confident in sustaining its growth trajectory, supported by strong demand indicators and a strategic focus on leveraging its comprehensive portfolio of solutions.

IQVIA Holdings: Strong Earnings and Strategic Growth
Oct 29, 2025

IQVIA Holdings’ recent earnings call conveyed a positive sentiment, highlighting strong financial performance and record-high free cash flow. The company demonstrated significant growth in net bookings and backlog, despite facing challenges in the R&D Solutions segment and delays in mega trials. IQVIA’s focus on AI and technology advancements underscores its optimism for future efficiencies and growth.

Cenobamate’s Real-World Impact: A New Hope for Focal Epilepsy?
Oct 27, 2025

Study Overview: The study titled Observational Cohort Study on Adult Patients With Not-adequately Controlled Focal-onset Seizures Treated With Cenobamate as Early Adjunctive Therapy in a Real-world Setting – FOCUS aims to evaluate the clinical response to cenobamate in adult patients with focal epilepsy in France, Germany, and Spain. The study is significant as it seeks to provide real-world data on the effectiveness of cenobamate for patients whose seizures are not adequately controlled by two or three anti-seizure medications (ASMs).

IQVIA’s Latest Clinical Study Update: A Game Changer in Cardiovascular Treatment?
Oct 27, 2025

Study Overview: The study titled ‘A Prospective, Open-Label, Multi-Country, Multicentre, Observational PoSt Market SurvEillance of VIVO ISAR’ aims to assess the safety and performance of the Polymer-Free Sirolimus Eluting Coronary Stent System in patients with coronary artery disease. The key objective is to evaluate clinical outcomes in patients undergoing percutaneous coronary intervention (PCI) with a short dual antiplatelet therapy (DAPT) regimen, highlighting its significance in real-world applications.

IQVIA’s Innovative Approach: The Carry Life UF System Study Update
Oct 27, 2025

Study Overview: The Carry Life@ UF System Clinical Study, officially titled ‘A Clinical Study With the Carry Life® UF System in Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients,’ aims to evaluate the effectiveness of the Carry Life UF system in enhancing ultrafiltration in CAPD patients. This study is significant as it could improve treatment outcomes for patients with End Stage Renal Disease by optimizing peritoneal dialysis processes.

IQVIA’s Latest Clinical Study on NOC-110: A Potential Game-Changer for Chronic Cough
Oct 27, 2025

Study Overview: The study titled A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Taplucainium Inhalation Powder (NOC-110) in Adults With Refractory or Unexplained Chronic Cough aims to evaluate the effectiveness, safety, and tolerability of NOC-110. This research is significant as it targets adults suffering from chronic coughs that are either unexplained or resistant to existing treatments.

IQVIA’s Latest Clinical Study Update: A New Hope for Peripheral Arterial Disease
Oct 27, 2025

IQVIA Holdings (IQV) has recently provided an update on a clinical study titled ‘Prospective, Multi-center, Single-arm Investigational Study of SWM-831 to Treat Moderate and Severely Calcified Femoropopliteal Arteries.’ The study aims to evaluate the safety and effectiveness of the SWM-831 device in treating peripheral arterial disease, specifically targeting calcified femoropopliteal arteries. This research is significant as it could offer new treatment options for patients with this condition.

IQVIA and Swedish Orphan Biovitrum’s PNH Study: A Potential Game-Changer for Pegcetacoplan
Oct 27, 2025

IQVIA Holdings and Swedish Orphan Biovitrum are collaborating on a clinical study titled ‘A Single Arm, Long-term, Multicentre Observational Study to Evaluate Effectiveness of Pegcetacoplan Under Real World Conditions in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH).’ The study aims to assess the real-world effectiveness of pegcetacoplan, a treatment for PNH, over a period of up to 72 months. This research is significant as it seeks to provide comprehensive data on the long-term impact of pegcetacoplan in a real-world setting.

QUVIVIQ® Pregnancy Registry: Insights into Insomnia Treatment During Pregnancy
Oct 27, 2025

Study Overview: The QUVIVIQ® Pregnancy Registry, officially titled ‘Registry to Collect Information on Pregnancy, Neonatal, and Infant Outcomes in Pregnant Women Exposed to QUVIVIQ®,’ aims to explore the effects of QUVIVIQ exposure on pregnancy, neonatal, and infant outcomes. This study is significant as it seeks to provide insights into the safety and implications of using QUVIVIQ, a treatment for insomnia, during pregnancy.

Executive/Board Changes
IQVIA Holdings Announces New CFO Appointment
Neutral
Sep 2, 2025

On September 2, 2025, IQVIA Holdings announced the appointment of Michael J. Fedock as Executive Vice President and Chief Financial Officer, effective February 28, 2026. This transition is part of the company’s CFO succession plan, with Fedock succeeding Ronald E. Bruehlman, who will retire and transition to a Senior Advisor role to the CEO. Fedock, with over 25 years of experience in the healthcare industry, has held several senior financial roles within IQVIA since joining in 2016. The transition aims to ensure continuity and support IQVIA’s long-term growth strategy, with Bruehlman having played a crucial role in the company’s transformation and growth since 2011.

The most recent analyst rating on (IQV) stock is a Buy with a $221.00 price target. To see the full list of analyst forecasts on IQVIA Holdings stock, see the IQV Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 29, 2025