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Profusa (PFSA)
NASDAQ:PFSA
US Market
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Profusa (PFSA) AI Stock Analysis

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PFSA

Profusa

(NASDAQ:PFSA)

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Neutral 42 (OpenAI - Gpt-5.6Sol)
Rating:42Neutral
Price Target:
$5.00
▲(192.40% Upside)
Action:Reiterated
Date:08/23/26
PFSA scores low primarily due to very weak financial performance (no revenue, widening losses, heavy cash burn, and negative equity with a small asset base), which creates substantial funding and execution risk. Technicals also pressure the score given the stock’s position below key moving averages and negative MACD. Valuation is not supportive because the company is loss-making (negative P/E) and has no dividend yield data.
Positive Factors
Debt Reduction
Converting secured debt into equity can reduce mandatory repayment pressure and improve financial flexibility. Although the transaction increases equity exposure and does not solve funding needs, it may strengthen the capital structure over the next several months.
Negative Factors
No Commercial Revenue
The absence of reported revenue indicates that Profusa remains pre-commercial and lacks demonstrated operating scale. Widening losses further suggest that expenses are rising ahead of commercialization, leaving the business dependent on future financing or successful strategic transactions.
Read all positive and negative factors
Positive Factors
Negative Factors
Debt Reduction
Converting secured debt into equity can reduce mandatory repayment pressure and improve financial flexibility. Although the transaction increases equity exposure and does not solve funding needs, it may strengthen the capital structure over the next several months.
Read all positive factors

Profusa (PFSA) vs. SPDR S&P 500 ETF (SPY)

Profusa Business Overview & Revenue Model

Company Description
Profusa, Inc. is a pioneering health technology firm that engineers advanced, bio-integrated sensors. These innovative devices, exemplified by their Lumee™ Oxygen Platform, are designed for uninterrupted observation of internal physiological marke...
How the Company Makes Money
null...

Profusa Financial Statement Overview

Summary
Financials indicate a very high-risk profile: no reported revenue, materially widening losses in TTM (net loss about $43.0M), and continued heavy operating/free cash flow burn (about -$21.0M). The balance sheet is stressed with negative equity (about -$27.1M in TTM) and debt (~$14.0M) far exceeding the very small asset base (~$1.0M), implying elevated dilution/refinancing risk despite some debt reduction and modest burn improvement versus 2025.
Income Statement
6
Very Negative
Balance Sheet
9
Very Negative
Cash Flow
12
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-2.00K0.000.000.000.000.00
EBITDA-35.04M-30.73M-4.81M-6.00M-13.22M-5.05M
Net Income-42.97M-35.82M-9.23M-10.28M-20.22M-10.31M
Balance Sheet
Total Assets1.04M3.77M3.07M1.89M1.03M11.36M
Cash, Cash Equivalents and Short-Term Investments719.00K1.78M191.00K142.00K78.00K856.00K
Total Debt14.00M14.81M48.21M40.40M31.03M24.02M
Total Liabilities28.17M30.43M122.28M111.89M100.80M95.02M
Stockholders Equity-27.13M-26.66M-119.20M-110.00M-99.77M-83.66M
Cash Flow
Free Cash Flow-21.04M-16.26M-2.07M-4.40M-7.70M-10.69M
Operating Cash Flow-20.95M-16.25M-2.07M-4.40M-7.70M-10.69M
Investing Cash Flow-7.43M-2.01M0.00-2.00K0.000.00
Financing Cash Flow28.92M19.84M2.12M4.47M6.92M8.75M

Profusa Risk Analysis

Profusa disclosed 80 risk factors in its most recent earnings report. Profusa reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Profusa Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
79
Outperform
$34.85B35.6536.19%15.54%77.43%
73
Outperform
$201.83B37.5010.52%2.41%8.06%-61.33%
68
Neutral
$119.49B24.899.85%3.43%8.43%3.17%
55
Neutral
$513.41M-4.28-165.83%90.63%-11.42%
52
Neutral
$151.95M-12.09-50.27%27.98%87.35%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
42
Neutral
$3.31M-0.0372.63%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PFSA
Profusa
5.46
-3,668.79
-99.85%
ABT
Abbott Laboratories
116.64
-12.25
-9.50%
DXCM
Dexcom
92.34
16.38
21.56%
MDT
Medtronic
93.35
4.21
4.72%
SENS
Senseonics Holdings
9.71
0.59
6.52%
OWLT
Owlet
5.20
-2.19
-29.63%

Profusa Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Profusa Strengthens Capital Structure Through Debt-to-Equity Exchange
Positive
Aug 21, 2026
On August 12, 2026, Profusa entered into a fifth amendment to its 2025 securities purchase agreement with Ascent Partners Fund, updating the amendment effective date, adding a new optional note form and resetting the exercise price of an existing ...
Shareholder MeetingsStock Split
Profusa Announces Approved Reverse Stock Split Implementation
Neutral
Aug 14, 2026
At its annual meeting on June 23, 2026, Profusa’s stockholders approved an amendment enabling a reverse stock split at a ratio within a specified range, with the final one-for-four split later set by the chief executive officer and filed wit...
Business Operations and StrategyDelistings and Listing ChangesM&A TransactionsRegulatory Filings and Compliance
Profusa Secures Option for Major Diagnostics Acquisition
Positive
Jul 31, 2026
On July 31, 2026, Profusa entered into an Option Agreement granting it the right, but not the obligation, to acquire G3 Vision Labs and its diagnostics subsidiaries, which generated an estimated $111 million in 2025 net revenues, in a deal structu...
Business Operations and StrategyExecutive/Board ChangesM&A TransactionsPrivate Placements and Financing
Profusa Plans Strategic Acquisition in Diagnostics Expansion
Positive
Jul 27, 2026
On July 27, 2026, Profusa announced it had signed a non-binding term sheet to acquire a privately held, commercial-stage health diagnostics and toxicology testing company, aiming to form a publicly traded diagnostics business with national CLIA-ce...
Financial DisclosuresRegulatory Filings and ComplianceShareholder MeetingsStock Split
Profusa Implements 1-for-25 Reverse Stock Split on Nasdaq
Neutral
Jul 6, 2026
At its annual meeting of stockholders on June 23, 2026, Profusa received shareholder approval to amend its certificate of incorporation to enable a reverse stock split at a ratio between 1-for-5 and 1-for-200, with the final terms delegated to the...
Business Operations and StrategyExecutive/Board ChangesM&A TransactionsPrivate Placements and FinancingRegulatory Filings and ComplianceShareholder MeetingsStock Split
Profusa Shareholders Approve Reverse Split and Governance Changes
Neutral
Jun 23, 2026
At a virtual special meeting of stockholders held on June 23, 2026, Profusa shareholders elected Lauren Chung as a Class I director to serve until the 2029 annual meeting, with a quorum established from 1.82 million shares represented. Investors a...
Business Operations and StrategyPrivate Placements and Financing
Profusa Taps Equity Line With Dilutive True-Up Mechanism
Negative
Jun 8, 2026
On June 8, 2026, Profusa, Inc. submitted an Advance Notice to Ascent Partners Fund LLC to draw on their existing equity line of credit under a Securities Purchase Agreement dated July 28, 2025 and amended December 22, 2025. For Advance Notices fro...
Business Operations and StrategyM&A Transactions
Profusa Amends PanOmics Acquisition Terms to Reduce Dilution
Positive
May 26, 2026
On May 22, 2026, Profusa Inc. and Bio Insights LLC executed a first amendment to their April 21, 2026 asset purchase agreement covering the $30 million acquisition of substantially all know-how assets tied to Bio Insights’ PanOmics Assay, an...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 23, 2026