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Ocular Therapeutix (OCUL)
NASDAQ:OCUL

Ocular Therapeutix (OCUL) AI Stock Analysis

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Ocular Therapeutix

(NASDAQ:OCUL)

Rating:55Neutral
Price Target:
$9.50
▼(-1.25%Downside)
Ocular Therapeutix's stock score reflects a combination of strong technical indicators and revenue growth, tempered by substantial operational losses and a negative P/E ratio. The bullish trend provides a positive short-term outlook, while the company needs to address profitability issues for long-term stability.
Positive Factors
Clinical Trials
The incorporation of re-dosing in SOL-1 allows the company to reduce the size of SOL-R while ensuring that it remains well powered for success, thus potentially accelerating the path to NDA submission.
Market Opportunity
There is a large market opportunity and unmet need for an extended wAMD treatment, which benefits both Axpaxli and Duravyu.
Regulatory Approval
FDA has agreed that SOL-1 and SOL-R together could constitute two complementary and adequate trials to support a potential New Drug Application (NDA) for AXPAXLI in wet AMD.
Negative Factors
Enrollment Risks
There is a risk that the current enrollment does not result in the expected number of patients for randomization.
Financial Performance
Total revenue was $10.7M, representing 27% YoY decline and missing our projection of $16.6M.

Ocular Therapeutix (OCUL) vs. SPDR S&P 500 ETF (SPY)

Ocular Therapeutix Business Overview & Revenue Model

Company DescriptionOcular Therapeutix, Inc. (OCUL) is a biopharmaceutical company focused on the development, manufacture, and commercialization of innovative therapies for eye diseases and conditions. Based in Bedford, Massachusetts, the company specializes in creating sustained-release therapies using its proprietary hydrogel platform technology to address unmet needs in ophthalmology. Ocular Therapeutix's core products include DEXTENZA for the treatment of ocular pain and inflammation following ophthalmic surgery, as well as a pipeline of other therapeutic candidates targeting various ocular conditions.
How the Company Makes MoneyOcular Therapeutix generates revenue primarily through the sale of its approved product, DEXTENZA, to healthcare providers and facilities. The company also engages in collaborative partnerships and licensing agreements to advance its pipeline products, which can involve upfront payments, milestone payments, and royalties. Additionally, Ocular Therapeutix may receive funding through research grants and government contracts to support its development activities. Significant factors contributing to its earnings include the successful commercialization of its products, the expansion of its market presence, and the advancement of its research and development pipeline.

Ocular Therapeutix Earnings Call Summary

Earnings Call Date:May 05, 2025
(Q4-2024)
|
% Change Since: 9.32%|
Next Earnings Date:Aug 11, 2025
Earnings Call Sentiment Positive
The earnings call highlighted significant progress with FDA approvals and strong trial retention. Financial stability and expansion opportunities in additional indications were also emphasized. However, there were delays in timeline for topline data and a reduction in trial size, indicating some operational adjustments.
Q4-2024 Updates
Positive Updates
FDA Approval for Amendment to SOL-1 Protocol
Received FDA approval for an amendment in SOL-1 to incorporate redosing at weeks 52 and 76, potentially increasing label flexibility to every six to 12 months.
Completion of SOL-1 Randomization
SOL-1 trial completed randomization ahead of schedule in December 2024 with 344 subjects.
Strong Patient Retention in SOL-1
Reported exceptional patient retention in SOL-1, with most rescue treatments aligning with prespecified criteria.
Financial Position and Cash Runway
Cash balance of $392 million as of December 31, 2024, with a cash runway into 2028.
Expansion Opportunities in NPDR and DME
Positive results from the HELIOS trial in NPDR and DME, with FDA feedback on clinical trial design expected in the first half of 2025.
Negative Updates
Delayed SOL-1 Topline Data
Topline data for SOL-1, including the 36-week primary endpoint, now expected in the first quarter of 2026 due to the need to maintain masking until week 52.
Reduction in SOL-R Trial Size
SOL-R trial size reduced from 825 to 555 subjects, potentially impacting the robustness of the data set.
Company Guidance
During the Ocular Therapeutix Fourth Quarter 2024 Earnings Conference Call, significant updates were shared regarding the registrational program for AXPAXLI in wet AMD. The FDA approved an amendment to the SOL-1 study's special protocol agreement, allowing redosing at weeks 52 and 76, aiming to secure a six to 12-month dosing label. This amendment is expected to enhance the drug's potential as a long-lasting treatment option. As a result, topline data for SOL-1 is now anticipated in the first quarter of 2026. The SOL-R study was optimized, reducing its size from 825 to 555 subjects while maintaining a robust statistical power of 90%. This change aims to accelerate the timeline for reporting data and regulatory submission. The company reported strong financial health with a cash balance of $392 million, projecting sufficient funding into 2028 without plans to raise additional capital in 2025.

Ocular Therapeutix Financial Statement Overview

Summary
Ocular Therapeutix has shown strong revenue growth and a solid cash position, but faces challenges with high operational losses and negative cash flows. The company needs to improve operational efficiency and achieve profitability to enhance financial stability.
Income Statement
40
Negative
Ocular Therapeutix has shown a steady increase in revenue over the years, with a notable TTM revenue of approximately $59.58 million from $17.40 million in 2020. However, the company consistently reports negative net income, indicating ongoing profitability challenges. The gross profit margin is healthy, but both the EBIT and EBITDA margins are significantly negative, reflecting substantial operational losses.
Balance Sheet
55
Neutral
The balance sheet reveals a strong cash position, with cash and equivalents exceeding total debt, resulting in negative net debt. Equity has grown significantly to $265.93 million in the TTM, and the company maintains a reasonable debt-to-equity ratio. However, the return on equity remains negative due to ongoing losses, highlighting profitability concerns despite a solid asset base.
Cash Flow
35
Negative
Ocular Therapeutix's cash flow statement shows consistent negative operating cash flow, with significant free cash flow deficits. Although the company has successfully raised financing in the past, the free cash flow to net income ratio remains unfavorable, indicating reliance on external funding rather than operational efficiency to sustain cash flows.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue59.58M63.72M58.44M51.49M43.52M17.40M
Gross Profit54.02M58.10M53.16M46.95M39.12M15.32M
EBITDA-180.18M-176.14M-66.42M-61.91M-75.62M-146.09M
Net Income-192.71M-193.51M-80.74M-63.42M-10.80M-159.63M
Balance Sheet
Total Assets405.92M457.94M252.06M149.29M204.89M261.86M
Cash, Cash Equivalents and Short-Term Investments349.68M392.10M195.81M102.30M164.16M228.06M
Total Debt76.22M75.78M83.39M64.28M58.98M58.44M
Total Liabilities139.99M142.59M160.93M113.91M116.89M185.77M
Stockholders Equity265.93M315.34M91.13M35.38M88.00M76.09M
Cash Flow
Free Cash Flow-148.43M-135.97M-76.32M-63.32M-66.74M-54.40M
Operating Cash Flow-145.46M-134.68M-70.23M-59.60M-65.55M-53.55M
Investing Cash Flow-2.97M-1.29M-6.09M-3.71M-1.19M-841.00K
Financing Cash Flow15.07M332.11M169.83M1.45M2.85M228.01M

Ocular Therapeutix Technical Analysis

Technical Analysis Sentiment
Positive
Last Price9.62
Price Trends
50DMA
8.17
Positive
100DMA
7.72
Positive
200DMA
8.48
Positive
Market Momentum
MACD
0.38
Negative
RSI
65.39
Neutral
STOCH
69.20
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OCUL, the sentiment is Positive. The current price of 9.62 is above the 20-day moving average (MA) of 8.90, above the 50-day MA of 8.17, and above the 200-day MA of 8.48, indicating a bullish trend. The MACD of 0.38 indicates Negative momentum. The RSI at 65.39 is Neutral, neither overbought nor oversold. The STOCH value of 69.20 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for OCUL.

Ocular Therapeutix Risk Analysis

Ocular Therapeutix disclosed 52 risk factors in its most recent earnings report. Ocular Therapeutix reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Ocular Therapeutix Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
$1.08B-12.27%3.08%-247.82%
57
Neutral
$1.09B-3.29%-23.12%97.46%
55
Neutral
$1.53B-57.19%-0.33%-3.59%
55
Neutral
$1.28B-49.41%4.86%10.13%
OPOPK
52
Neutral
$1.08B-3.04%-13.79%82.82%
52
Neutral
$7.50B0.31-61.87%2.27%17.10%1.59%
42
Neutral
$1.48B-69.30%-68.13%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OCUL
Ocular Therapeutix
9.62
2.96
44.44%
OPK
Opko Health
1.36
0.07
5.43%
PCRX
Pacira Pharmaceuticals
23.22
2.62
12.72%
BLFS
BioLife Solutions
22.84
2.39
11.69%
VRDN
Viridian Therapeutics
15.67
3.36
27.29%
ETNB
89bio
10.16
2.26
28.61%

Ocular Therapeutix Corporate Events

Shareholder MeetingsBusiness Operations and Strategy
Ocular Therapeutix Approves Key Amendments at Annual Meeting
Neutral
Jun 11, 2025

On June 11, 2025, Ocular Therapeutix held its Annual Meeting of Stockholders, where several key amendments were approved. These included increasing shares under the 2021 Stock Incentive Plan and the 2014 Employee Stock Purchase Plan, as well as updating the company’s Certificate of Incorporation to include officer exculpation. Additionally, the company completed enrollment for its SOL-R Phase 3 clinical trial for AXPAXLI, a treatment for wet AMD, on May 31, 2025, ensuring sufficient subjects for its target randomization.

The most recent analyst rating on (OCUL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on Ocular Therapeutix stock, see the OCUL Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 25, 2025