Neuropace, Inc. (NPCE)
:NPCE
US Market
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NeuroPace (NPCE) AI Stock Analysis

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NPCE

NeuroPace

(NASDAQ:NPCE)

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Neutral 61 (OpenAI - 4o)
Rating:61Neutral
Price Target:
$14.00
▲(8.19% Upside)
NeuroPace's overall score is driven by strong earnings call results, highlighting revenue growth and positive EBITDA, which are significant positives. However, financial performance concerns, including high leverage and negative profitability, weigh down the score. Technical indicators show strong momentum, but valuation remains a concern due to negative earnings.
Positive Factors
Revenue Growth
The significant revenue growth indicates strong market demand and successful product adoption, supporting long-term business expansion.
Positive Adjusted EBITDA
Achieving positive adjusted EBITDA demonstrates improved operational efficiency and scalability, enhancing financial stability.
Strong Gross Margins
Sustained high gross margins reflect effective cost management and pricing power, contributing to long-term profitability.
Negative Factors
High Leverage
High leverage can increase financial risk and limit flexibility, potentially impacting the company's ability to invest in growth opportunities.
Negative Profitability
Ongoing profitability challenges may hinder reinvestment in innovation and expansion, affecting long-term competitive positioning.
Extended Timeline for Pediatric Indication
Delays in regulatory submissions can slow product diversification and market expansion, impacting future revenue streams.

NeuroPace (NPCE) vs. SPDR S&P 500 ETF (SPY)

NeuroPace Business Overview & Revenue Model

Company DescriptionNeuroPace, Inc. is a medical technology company focused on developing innovative solutions for neurological disorders, particularly epilepsy. The company operates within the healthcare sector, specializing in the design, manufacturing, and commercialization of neuromodulation devices. Its flagship product, the RNS System, is an implantable device that monitors and responds to abnormal electrical activity in the brain to prevent seizures in patients with drug-resistant epilepsy. NeuroPace aims to improve the quality of life for patients through advanced neurostimulation technology.
How the Company Makes MoneyNeuroPace generates revenue primarily through the sale of its RNS System and its associated services. The company sells its devices to hospitals, clinics, and healthcare providers, who then implant them into eligible patients. Key revenue streams include the initial sale of the RNS System, which comprises the implantable device and the external components, as well as ongoing revenues from patient monitoring services and device maintenance. Partnerships with healthcare institutions and neurologists play a significant role in driving adoption of the RNS System, while reimbursement from insurance providers for the device and its implantation also contributes to the company’s earnings. Additionally, NeuroPace may benefit from research collaborations and clinical studies that validate the effectiveness of its technology, further enhancing its market position.

NeuroPace Earnings Call Summary

Earnings Call Date:Nov 04, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 10, 2026
Earnings Call Sentiment Positive
The earnings call highlighted strong revenue growth, positive adjusted EBITDA, and increased guidance. There were challenges, including the winding down of the DIXI product line and extended timelines for pediatric indication, but these were outweighed by positive developments and strategic progress.
Q3-2025 Updates
Positive Updates
Record Revenue and Growth
NeuroPace achieved a total revenue of $27.4 million in Q3 2025, marking a 30% year-over-year growth compared to $21.1 million in the prior year quarter. This was driven by RNS initial implants, with RNS revenue at $22.6 million, representing a 31% year-over-year growth.
Positive Adjusted EBITDA
NeuroPace generated positive adjusted EBITDA for the first time in its history, reflecting strong scalability and disciplined expense management.
Increased Revenue and Gross Margin Guidance
Full year revenue guidance was raised to $97 million to $98 million, up from $94 million to $98 million, reflecting a 21% to 23% year-over-year growth. Gross margin guidance was also increased to 76% to 77%, up from 75% to 76%.
FDA Submission Progress
Progress was made with the NAUTILUS study and the pediatric indication. The PMA supplement for NAUTILUS is on track to be submitted before year-end.
Strong RNS System Performance
RNS System gross margin remained above 80%, benefiting from improved manufacturing efficiency and favorable pricing.
Peer Recognition
The RNS System was featured in the Journal of Clinical Neurophysiology, highlighting its unique closed-loop stimulation capabilities.
Negative Updates
DIXI Product Line Wind Down
DIXI sales, which amounted to approximately $4 million in the quarter, are ending with the distribution agreement officially concluded on September 30. The wind-down period lasts until the end of Q1 2026.
Extended Timeline for Pediatric Indication
The timeline for the pediatric indication submission has been extended beyond 2025 due to the time taken to align the protocol and data set.
Net Loss
Net loss for the quarter was $3.5 million, compared to a net loss of $5.5 million in the prior year period.
Company Guidance
During the Q3 2025 earnings call, NeuroPace provided updated financial guidance, highlighting record quarterly revenue of $27.4 million, a 30% year-over-year growth driven primarily by RNS initial implants. The RNS revenue reached $22.6 million, marking a 31% increase from the previous year, with broad-based growth across geographies and programs. The company improved its full-year revenue guidance to $97-$98 million, anticipating a 21%-23% annual growth. Gross margins were also strong at 77.4%, up from 73.2% the previous year, with expectations for full-year margins to be between 76% and 77%. Notably, NeuroPace achieved positive adjusted EBITDA for the first time, attributed to disciplined expense management and operational efficiency. The company remains committed to a long-term growth trajectory, targeting a minimum of 20% growth in its core RNS business.

NeuroPace Financial Statement Overview

Summary
NeuroPace shows revenue growth potential with a 7.1% increase in TTM, but struggles with profitability due to negative net profit and EBIT margins. The high debt-to-equity ratio and negative return on equity indicate financial risk, despite improvements in free cash flow.
Income Statement
45
Neutral
NeuroPace shows a positive revenue growth trend with a 7.1% increase in TTM, indicating potential market expansion. However, the company struggles with profitability, as evidenced by negative net profit and EBIT margins. The gross profit margin is strong at 76.8%, but the negative net profit margin of -21.6% highlights ongoing challenges in cost management and operational efficiency.
Balance Sheet
40
Negative
The balance sheet reveals a high debt-to-equity ratio of 3.84, indicating significant leverage and potential financial risk. Return on equity is negative, reflecting losses and inefficiencies in generating shareholder value. The equity ratio stands at 17.3%, suggesting a moderate reliance on equity financing.
Cash Flow
50
Neutral
Cash flow analysis shows improvement in free cash flow growth, with a notable increase of 91.3% in TTM. The operating cash flow to net income ratio is negative, indicating cash flow challenges. However, the free cash flow to net income ratio is positive, suggesting some ability to cover net losses with free cash flow.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue94.86M79.91M65.42M45.52M45.18M41.14M
Gross Profit72.83M59.09M48.12M32.49M33.44M30.27M
EBITDA-15.16M-16.57M-22.83M-36.57M-28.37M-12.48M
Net Income-23.99M-27.14M-32.96M-47.08M-36.08M-24.28M
Balance Sheet
Total Assets107.25M94.65M107.65M114.11M133.56M55.95M
Cash, Cash Equivalents and Short-Term Investments60.01M52.76M66.45M77.41M115.58M38.08M
Total Debt71.18M73.34M72.39M69.77M49.85M52.86M
Total Liabilities88.74M86.63M87.00M79.33M60.06M203.78M
Stockholders Equity18.52M8.01M20.65M34.78M73.50M-147.83M
Cash Flow
Free Cash Flow-16.58M-18.25M-19.87M-37.47M-24.96M-21.67M
Operating Cash Flow-16.31M-17.95M-19.70M-36.87M-24.58M-21.61M
Investing Cash Flow1.73M8.99M23.03M23.80M-85.40M-10.77M
Financing Cash Flow19.81M4.33M8.13M490.00K102.53M55.01M

NeuroPace Technical Analysis

Technical Analysis Sentiment
Positive
Last Price12.94
Price Trends
50DMA
10.82
Positive
100DMA
10.05
Positive
200DMA
11.26
Positive
Market Momentum
MACD
0.76
Negative
RSI
64.50
Neutral
STOCH
77.00
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For NPCE, the sentiment is Positive. The current price of 12.94 is above the 20-day moving average (MA) of 11.53, above the 50-day MA of 10.82, and above the 200-day MA of 11.26, indicating a bullish trend. The MACD of 0.76 indicates Negative momentum. The RSI at 64.50 is Neutral, neither overbought nor oversold. The STOCH value of 77.00 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for NPCE.

NeuroPace Risk Analysis

NeuroPace disclosed 61 risk factors in its most recent earnings report. NeuroPace reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

NeuroPace Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
$495.40M28.638.80%9.28%21.00%
61
Neutral
$431.00M-169.27%24.08%24.08%
58
Neutral
$315.35M1,001.161.94%251.54%
55
Neutral
$400.06M-12.92%10.75%-7.15%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$478.53M-59.78%
45
Neutral
$241.06M-129.29%31.94%36.59%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
NPCE
NeuroPace
13.02
3.83
41.68%
DCTH
Delcath Systems
8.65
-0.98
-10.18%
SENS
Senseonics Holdings
5.98
-0.36
-5.68%
TCMD
Tactile Systems Technology
23.19
7.63
49.04%
RXST
RxSight
9.60
-35.21
-78.58%
CBLL
Ceribell, Inc.
13.20
-11.86
-47.33%

NeuroPace Corporate Events

NeuroPace, Inc. Reports Record Revenue and Growth
Nov 6, 2025

In a recent earnings call, NeuroPace, Inc. showcased a robust financial performance with strong revenue growth and positive adjusted EBITDA. Despite some challenges, such as the winding down of the DIXI product line and extended timelines for pediatric indication, the overall sentiment was optimistic, driven by strategic progress and positive developments.

NeuroPace Reports Record Revenue and Raises Guidance
Nov 5, 2025

NeuroPace, Inc., based in Mountain View, California, is a medical device company specializing in innovative solutions for epilepsy, notably through its RNS System, a brain-responsive platform aimed at reducing seizures in patients with drug-resistant epilepsy.

Neuropace, Inc. Advances in Treating Lennox-Gastaut Syndrome: A Study Update
Oct 27, 2025

Study Overview: The RNS System LGS Feasibility Study, officially titled RNS System Feasibility Study of Thalamocortical Brain-Responsive Neurostimulation for the Treatment of Lennox-Gastaut Syndrome, aims to gather preliminary safety and effectiveness data for brain-responsive neurostimulation. This study targets individuals aged 12 or older with Lennox-Gastaut Syndrome (LGS) who do not respond to antiseizure medications. The goal is to assess the feasibility of a larger pivotal study to expand the RNS System’s use for treating medically intractable LGS.

NeuroPace, Inc. Reports Record Revenue and Strong Margins in Q2 2025 Earnings Call
Sep 1, 2025

In the latest earnings call, NeuroPace, Inc. demonstrated a strong performance with record revenue and improved gross margins, despite facing challenges such as increased operating expenses and a higher net loss. The company also shared positive clinical trial data, although the NAUTILUS trial did not meet its primary effectiveness endpoint.

Neuropace’s Innovative Approach to Treating Lennox-Gastaut Syndrome
Aug 14, 2025

Neuropace, Inc. is conducting a study titled ‘RNS System Feasibility Study of Thalamocortical Brain-Responsive Neurostimulation for the Treatment of Lennox-Gastaut Syndrome’. The study aims to assess the safety and effectiveness of brain-responsive neurostimulation in reducing generalized seizures in patients aged 12 and older with Lennox-Gastaut Syndrome (LGS) who do not respond to antiseizure medications. This research is significant as it seeks to expand the use of the RNS System for treating medically intractable LGS.

NeuroPace Reports Record Revenue and Raises Guidance
Aug 13, 2025

NeuroPace, Inc., based in Mountain View, California, is a medical device company specializing in innovative solutions for epilepsy treatment, notably through its RNS System, a brain-responsive platform that offers personalized, real-time seizure management. In its latest earnings report for the second quarter of 2025, NeuroPace announced a record quarterly revenue of $23.5 million, marking a 22% increase year-over-year. The company also raised its full-year revenue guidance to between $94 million and $98 million, reflecting strong market performance and strategic advancements.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 08, 2025