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Neuropace, Inc. (NPCE)
NASDAQ:NPCE
US Market
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NeuroPace (NPCE) AI Stock Analysis

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NPCE

NeuroPace

(NASDAQ:NPCE)

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Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
$15.50
▲(10.01% Upside)
Action:Reiterated
Date:05/14/26
The score is held down primarily by weak financial fundamentals—recent TTM growth reversal, ongoing losses and cash burn, and elevated leverage with a thin equity cushion. The earnings call was a meaningful positive with raised guidance, improving adjusted profitability outlook, and strong commercial/clinical momentum, while technicals are mixed-to-mildly constructive and valuation signals are limited based on the provided P/E and dividend data.
Positive Factors
High gross margins and pricing power
Sustained gross margins above 80% imply durable unit economics for the RNS System, providing a large margin buffer to fund R&D and commercial expansion. High margins improve operating leverage potential and reduce sensitivity to reimbursement pressure, supporting long-term profitability if volume scales.
Negative Factors
High leverage and thin equity cushion
Elevated leverage with a materially compressed equity base reduces financial flexibility and heightens refinancing or covenant risk. In a capital‑intensive adoption cycle this raises the probability of dilution or higher funding costs, constraining strategic investments and resilience to demand shocks.
Read all positive and negative factors
Positive Factors
Negative Factors
High gross margins and pricing power
Sustained gross margins above 80% imply durable unit economics for the RNS System, providing a large margin buffer to fund R&D and commercial expansion. High margins improve operating leverage potential and reduce sensitivity to reimbursement pressure, supporting long-term profitability if volume scales.
Read all positive factors

NeuroPace (NPCE) vs. SPDR S&P 500 ETF (SPY)

NeuroPace Business Overview & Revenue Model

Company Description
NeuroPace, Inc. operates as a medical device company in the United States. It develops and sells RNS system, a brain-responsive neuromodulation system for treating medically refractory focal epilepsy by delivering personalized real-time treatment ...
How the Company Makes Money
NeuroPace primarily makes money by selling its RNS System for use in eligible epilepsy patients. Revenue is generated from (1) sales of implantable neurostimulation devices and related components used in the initial implant procedure, and (2) sale...

NeuroPace Earnings Call Summary

Earnings Call Date:May 12, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 06, 2026
Earnings Call Sentiment Positive
The call conveyed strong commercial and clinical momentum: double-digit RNS revenue growth (CFO reported ~20% YoY excluding DIXI), raised full-year guidance, improved adjusted EBITDA outlook, robust clinical data (NAUTILUS 18-month and 3-year focal outcomes), and tangible AI/product roadmap progress. Offsetting risks include the NAUTILUS primary endpoint nuance, IGE revenue timing and payer coverage uncertainty, seasonally lower cash, and ongoing need for reimbursement work. Overall, management presented disciplined investment and operating leverage alongside meaningful opportunities that outweigh near-term risks.
Positive Updates
Quarterly Revenue and RNS System Growth
Q1 2026 revenue of $22.1M (or $22.0M excluding DIXI), driven by RNS system revenue of $21.7M. Management highlighted underlying RNS momentum and the CFO reported excluding DIXI non-GAAP revenue of $22.0M, a 20.1% year-over-year increase versus $18.3M in Q1 2025; RNS system revenue grew ~19.5% year-over-year (from $18.2M to $21.7M).
Negative Updates
NAUTILUS Primary Endpoint Uncertainty
Analyst discussion noted the NAUTILUS trial's primary efficacy endpoint did not meet statistical significance (while multiple secondary and supportive analyses were favorable); management emphasized FDA is assessing the totality of evidence but the primary endpoint result introduces potential label and review risk and may affect timing/extent of commercial uptake for IGE.
Read all updates
Q1-2026 Updates
Negative
Quarterly Revenue and RNS System Growth
Q1 2026 revenue of $22.1M (or $22.0M excluding DIXI), driven by RNS system revenue of $21.7M. Management highlighted underlying RNS momentum and the CFO reported excluding DIXI non-GAAP revenue of $22.0M, a 20.1% year-over-year increase versus $18.3M in Q1 2025; RNS system revenue grew ~19.5% year-over-year (from $18.2M to $21.7M).
Read all positive updates
Company Guidance
NeuroPace raised full‑year 2026 revenue guidance to $99.0–$101.0 million (up from $98.0–$100.0M), driven by an expected 21%–23% underlying RNS system revenue growth (guidance excludes any IGE contribution), and now includes roughly $0.5M of service revenue (the $1M midpoint uplift was ~$0.5M from service visibility and ~$0.5M from core RNS). Q1 product revenue was $22.1M ($22.0M excluding DIXI) with RNS revenue of $21.7M, and the company expects full‑year adjusted gross margin of 81.5%–82.5%. Full‑year non‑GAAP operating expenses are guided to $90M–$92M (excluding about $10M of stock‑based comp), with S&M $46M–$48M, R&D ≈$27M, and G&A ≈$17M, and adjusted EBITDA is expected to be a loss of $8.5M–$9.5M (improved from prior -$9M to -$10M); any IGE-driven revenue would be modeled only after regulatory approval and reimbursement visibility.

NeuroPace Financial Statement Overview

Summary
Despite strong gross margins (~74–78%) and multi-year revenue expansion, the latest TTM shows a sharp revenue growth reversal (-45.6%) alongside continued losses (TTM operating margin ~-11%, net margin ~-15%). Cash flow remains negative (TTM FCF -$9.7M) and the balance sheet is pressured by high leverage versus a reduced equity base (debt-to-equity ~4.9x), elevating financing risk.
Income Statement
42
Neutral
Balance Sheet
28
Negative
Cash Flow
34
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue99.53M99.99M79.91M65.42M45.52M45.18M
Gross Profit77.93M77.22M59.09M48.12M32.49M33.44M
EBITDA-14.88M-14.39M-16.57M-22.83M-36.57M-28.37M
Net Income-21.57M-21.46M-27.14M-32.96M-47.08M-36.08M
Balance Sheet
Total Assets98.90M105.56M94.65M107.65M114.11M133.56M
Cash, Cash Equivalents and Short-Term Investments53.98M61.06M52.76M66.45M77.41M115.58M
Total Debt70.46M70.84M73.34M72.39M69.77M49.85M
Total Liabilities84.44M86.53M86.63M87.00M79.33M60.06M
Stockholders Equity14.45M19.03M8.01M20.65M34.78M73.50M
Cash Flow
Free Cash Flow-9.84M-11.34M-18.25M-19.87M-37.47M-24.96M
Operating Cash Flow-9.42M-11.01M-17.95M-19.70M-36.87M-24.58M
Investing Cash Flow-412.00K-332.00K8.99M23.03M23.80M-85.40M
Financing Cash Flow-1.67M19.60M4.33M8.13M490.00K102.53M

NeuroPace Technical Analysis

Technical Analysis Sentiment
Positive
Last Price14.09
Price Trends
50DMA
15.48
Positive
100DMA
15.44
Positive
200DMA
13.67
Positive
Market Momentum
MACD
0.13
Positive
RSI
53.58
Neutral
STOCH
75.99
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For NPCE, the sentiment is Positive. The current price of 14.09 is below the 20-day moving average (MA) of 16.67, below the 50-day MA of 15.48, and above the 200-day MA of 13.67, indicating a bullish trend. The MACD of 0.13 indicates Positive momentum. The RSI at 53.58 is Neutral, neither overbought nor oversold. The STOCH value of 75.99 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for NPCE.

NeuroPace Risk Analysis

NeuroPace disclosed 80 risk factors in its most recent earnings report. NeuroPace reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

NeuroPace Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
72
Outperform
$561.65M-83.609.70%17.18%34.07%
68
Neutral
$380.43M-78.100.51%67.95%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$251.90M-4.00-17.01%-14.05%-70.35%
49
Neutral
$330.97M-2.36-130.00%71.91%14.73%
49
Neutral
$712.18M-8.74-38.19%
47
Neutral
$576.87M-16.57-120.74%18.06%21.86%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
NPCE
NeuroPace
16.68
4.22
33.87%
DCTH
Delcath Systems
10.83
-5.36
-33.11%
SENS
Senseonics Holdings
6.43
-4.18
-39.41%
TCMD
Tactile Systems Technology
25.06
15.22
154.67%
RXST
RxSight
5.99
-10.11
-62.80%
CBLL
Ceribell, Inc.
18.80
1.61
9.37%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 14, 2026