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MapLight Therapeutics, Inc. (MPLT)
NASDAQ:MPLT
US Market

MapLight Therapeutics, Inc. (MPLT) AI Stock Analysis

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MPLT

MapLight Therapeutics, Inc.

(NASDAQ:MPLT)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$17.50
▲(0.06% Upside)
Action:ReiteratedDate:01/09/26
The score is held back primarily by pre-revenue financials with widening losses and increasing cash burn, partially offset by a comparatively strong, low-leverage balance sheet. Recent corporate events (large IPO/private placement and stated runway through 2027) improve near-term funding visibility, while technical indicators are mixed/neutral and valuation cannot be assessed from the provided data.
Positive Factors
Low leverage / strong balance sheet
Very low debt relative to equity gives durable financial flexibility for a clinical-stage biotech. It supports continued R&D investment, reduces short-term solvency risk, and allows the company to fund operations or opportunistic partnerships without being forced into distressed financing.
Negative Factors
Pre-revenue with widening net losses
Sustained, expanding losses are a structural risk for a clinical-stage company: absent commercial revenue the business is reliant on financing markets and milestone success. Persistent widening losses increase the likelihood of future dilutive financings and place a premium on achieving clinical proof points.
Read all positive and negative factors
Positive Factors
Negative Factors
Low leverage / strong balance sheet
Very low debt relative to equity gives durable financial flexibility for a clinical-stage biotech. It supports continued R&D investment, reduces short-term solvency risk, and allows the company to fund operations or opportunistic partnerships without being forced into distressed financing.
Read all positive factors

MapLight Therapeutics, Inc. (MPLT) vs. SPDR S&P 500 ETF (SPY)

MapLight Therapeutics, Inc. Business Overview & Revenue Model

Company Description
MapLight Therapeutics, Inc. operates as a clinical-stage biopharmaceutical company for patients suffering from debilitating central nervous system disorders. The company's products include ML-007C-MA, a fixed-dose combination of an M 1 /M 4 muscar...
How the Company Makes Money
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MapLight Therapeutics, Inc. Financial Statement Overview

Summary
Income statement and cash flow are weak: the company is pre-revenue with widening losses and accelerating operating/free cash outflows. The balance sheet is a relative strength with low leverage versus equity, but deeply negative returns and rising burn create ongoing financing/dilution risk.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
BreakdownTTMDec 2024Dec 2023Dec 2022
Income Statement
Total Revenue0.000.000.000.00
Gross Profit-438.00K-701.00K-556.00K-574.00K
EBITDA-105.83M-76.88M-55.15M-29.44M
Net Income-102.83M-77.58M-55.71M-30.02M
Balance Sheet
Total Assets257.22M136.92M91.41M39.39M
Cash, Cash Equivalents and Short-Term Investments227.17M108.80M79.77M27.66M
Total Debt6.01M6.58M5.92M6.27M
Total Liabilities23.70M21.72M20.13M18.52M
Stockholders Equity233.52M115.19M71.28M20.87M
Cash Flow
Free Cash Flow-113.00M-79.58M-52.47M-27.32M
Operating Cash Flow-112.80M-78.81M-52.01M-26.58M
Investing Cash Flow-48.26M-80.79M-462.00K-746.00K
Financing Cash Flow197.86M118.06M104.57M33.17M

MapLight Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$774.97M-6.46-81.38%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$41.35M-0.65-80.00%9.63%
49
Neutral
$580.12K-0.24178.82%-4121.10%
47
Neutral
$4.45M-0.76-203.36%90.53%
43
Neutral
$3.74M-0.15-381.74%98.22%
43
Neutral
$4.81M-0.12-215.04%-100.00%93.82%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MPLT
MapLight Therapeutics, Inc.
16.98
-1.36
-7.42%
SCNI
Scinai Immunotherapeutics
0.67
-2.69
-79.99%
SNSE
Sensei Biotherapeutics
29.97
20.90
230.50%
GRI
GRI Bio
2.43
-185.17
-98.70%
DRMA
Dermata Therapeutics
1.55
-11.95
-88.52%
AZTR
Azitra Inc
0.27
-1.94
-87.65%

MapLight Therapeutics, Inc. Corporate Events

Business Operations and StrategyProduct-Related Announcements
MapLight updates trial timelines and highlights CNS pipeline
Positive
Jan 9, 2026
On January 9, 2026, MapLight Therapeutics announced it now expects topline Phase 2 results for its ZEPHYR and IRIS clinical trials—evaluating ML-007C-MA in schizophrenia and ML-004 in autism spectrum disorder—to be disclosed in the thi...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 09, 2026