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MapLight Therapeutics, Inc. (MPLT)
NASDAQ:MPLT
US Market

MapLight Therapeutics, Inc. (MPLT) AI Stock Analysis

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MPLT

MapLight Therapeutics, Inc.

(NASDAQ:MPLT)

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Neutral 56 (OpenAI - 5.2)
Rating:56Neutral
Price Target:
$28.00
▲(60.09% Upside)
Action:ReiteratedDate:04/11/26
The score is held back primarily by persistent pre-revenue losses and worsening cash burn, which increases future financing risk. Offsetting this are a strong, lightly levered balance sheet and a positive corporate update indicating runway into 2027 with meaningful clinical catalysts ahead. Technically, the trend is strong but currently very overbought, limiting the near-term technical score, and valuation support is limited due to negative earnings and no dividend.
Positive Factors
Strong balance sheet / low leverage
Very low financial leverage and sizable equity provide durable financial flexibility for a clinical-stage biotech. This reduces near-term refinancing pressure, allows continued investment in trials, and gives management optionality to fund programs without immediate debt reliance, supporting multi-year development plans.
Negative Factors
Persistent pre-revenue losses
Being pre-revenue with materially widening net losses creates a durable structural weakness: the company must rely on external capital until commercialization. Growing losses increase the magnitude and frequency of financing needs, diluting shareholders and forcing trade-offs between program funding and balance sheet preservation.
Read all positive and negative factors
Positive Factors
Negative Factors
Strong balance sheet / low leverage
Very low financial leverage and sizable equity provide durable financial flexibility for a clinical-stage biotech. This reduces near-term refinancing pressure, allows continued investment in trials, and gives management optionality to fund programs without immediate debt reliance, supporting multi-year development plans.
Read all positive factors

MapLight Therapeutics, Inc. (MPLT) vs. SPDR S&P 500 ETF (SPY)

MapLight Therapeutics, Inc. Business Overview & Revenue Model

Company Description
MapLight Therapeutics, Inc. operates as a clinical-stage biopharmaceutical company for patients suffering from debilitating central nervous system disorders. The company's products include ML-007C-MA, a fixed-dose combination of an M 1 /M 4 muscar...
How the Company Makes Money
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MapLight Therapeutics, Inc. Financial Statement Overview

Summary
Mixed fundamentals. The balance sheet is strong with very low leverage (debt-to-equity ~0.01) and sizable equity, but the income statement and cash flow are weak with no revenue, widening net losses in 2025 (~$161M vs. ~$78M in 2024), and accelerating cash burn (operating cash flow about -$138M in 2025). This raises financing/dilution risk despite current capitalization.
Income Statement
18
Very Negative
Balance Sheet
78
Positive
Cash Flow
34
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022
Income Statement
Total Revenue0.000.000.000.00
Gross Profit-578.00K-701.00K-556.00K-574.00K
EBITDA-168.50M-76.88M-55.15M-29.44M
Net Income-161.15M-77.58M-55.71M-30.02M
Balance Sheet
Total Assets479.51M136.92M91.41M39.39M
Cash, Cash Equivalents and Short-Term Investments305.10M108.80M79.77M27.66M
Total Debt5.80M6.58M5.92M6.27M
Total Liabilities21.14M21.72M20.13M18.52M
Stockholders Equity458.37M115.19M71.28M20.87M
Cash Flow
Free Cash Flow-138.61M-79.58M-52.47M-27.32M
Operating Cash Flow-138.14M-78.81M-52.01M-26.58M
Investing Cash Flow-323.21M-80.79M-462.00K-746.00K
Financing Cash Flow469.82M118.06M104.57M33.17M

MapLight Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$1.12B-4.80-75.96%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$40.41M-0.71-80.00%9.63%
44
Neutral
$2.05M-0.20178.82%-4121.10%
44
Neutral
$5.23M-0.28-203.36%90.53%
43
Neutral
$3.47M-0.15-381.74%98.22%
43
Neutral
$3.45M-0.14-215.04%-100.00%93.82%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MPLT
MapLight Therapeutics, Inc.
27.02
8.68
47.33%
SCNI
Scinai Immunotherapeutics
0.59
-1.33
-69.22%
SNSE
Sensei Biotherapeutics
28.70
19.54
213.32%
GRI
GRI Bio
2.44
-41.52
-94.45%
DRMA
Dermata Therapeutics
1.25
-6.54
-83.95%
AZTR
Azitra Inc
0.22
-1.73
-88.89%

MapLight Therapeutics, Inc. Corporate Events

Business Operations and StrategyFinancial Disclosures
MapLight Therapeutics Highlights Growing CNS Pipeline, Strong Cash Position
Positive
Mar 26, 2026
On March 26, 2026, MapLight Therapeutics reported fourth-quarter and full-year 2025 results, highlighting an expanding CNS pipeline and increased RD investment. The company is advancing ML-007C-MA for schizophrenia and Alzheimer’s disease ps...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 11, 2026