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Lantheus (LNTH)
NASDAQ:LNTH
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Lantheus (LNTH) AI Stock Analysis

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LNTH

Lantheus

(NASDAQ:LNTH)

Rating:58Neutral
Price Target:
$58.00
▲(2.04% Upside)
Lantheus faces significant challenges with a lowered financial outlook and bearish technical indicators, which weigh heavily on its stock score. Despite these challenges, strong financial performance and strategic initiatives offer potential for future improvement.
Positive Factors
Analyst Confidence
Analyst reiterates the Buy rating, expressing long-term confidence in the company's potential despite current challenges.
Portfolio Expansion
The acquisition of Life Molecular Imaging added the FDA-approved NEURACEQ to LNTH's portfolio, expanding its diagnostic and therapeutic capabilities.
Stock Buyback
The Board of Directors authorized the repurchase of up to $400M of LNTH's common stock, which can be seen as a vote of confidence in the company's future value.
Negative Factors
Competitive Pressures
Management highlighted intensified competitive pressures in the market, particularly affecting Pylarify revenues.
Market Share Loss
Management expects continued market share loss, coupled with net price decline, in both the third and fourth quarter.
Revenue Guidance Cut
The company lowered its guidance for the fiscal year, indicating significant cuts in both revenue and EPS projections.

Lantheus (LNTH) vs. SPDR S&P 500 ETF (SPY)

Lantheus Business Overview & Revenue Model

Company DescriptionLantheus Holdings, Inc. is a global leader in the development, manufacturing, and commercialization of innovative diagnostic imaging agents and therapies, primarily focused on oncology, cardiology, and neurology. The company specializes in radiopharmaceuticals and molecular imaging, offering products that aid in the detection and treatment of various diseases, including cancer. Its core products include Positron Emission Tomography (PET) imaging agents and other medical imaging solutions that enhance diagnostic accuracy and patient care.
How the Company Makes MoneyLantheus generates revenue primarily through the sale of its diagnostic imaging agents and related products. The company's revenue model is based on the commercialization of its proprietary radiopharmaceuticals, which are sold to hospitals, imaging centers, and other healthcare providers. Key revenue streams include direct sales of its imaging agents, such as Gallium-68 and other PET tracers, as well as collaboration agreements with pharmaceutical companies for the development and distribution of novel imaging agents. Additionally, Lantheus may benefit from strategic partnerships and collaborations, which can enhance its product offerings and expand its market reach, contributing to its overall earnings.

Lantheus Earnings Call Summary

Earnings Call Date:Aug 06, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Oct 30, 2025
Earnings Call Sentiment Neutral
The earnings call highlighted strategic moves to enhance the company's portfolio and diversify revenue streams, such as the FDA acceptance of a new PYLARIFY formulation and key acquisitions. However, it also addressed significant challenges, including a lowered financial outlook and competitive pressures affecting PYLARIFY sales. Despite strategic efforts, the lowlights weigh heavily, indicating ongoing market challenges.
Q2-2025 Updates
Positive Updates
FDA Acceptance of New PYLARIFY Formulation
The FDA accepted Lantheus' NDA for a new formulation of PYLARIFY, which increases batch size by approximately 50%, enhancing patient access, supply resilience, and production efficiency.
Strategic Acquisitions Enhance Portfolio
The acquisitions of Evergreen and Life Molecular Imaging (LMI) added complementary capabilities, immediate growth drivers, and diversified revenue streams. Neuraceq, a PET imaging agent for Alzheimer's, is expected to contribute $40 million to $45 million in revenue annually.
New $400 Million Stock Repurchase Program
The Board authorized a $400 million stock repurchase program, reflecting confidence in the company's strategy and financial position.
DEFINITY Performance
DEFINITY sales increased by 7.5% year-over-year, maintaining market strength despite competitor re-entries.
Negative Updates
Lowered Financial Outlook for 2025
Lantheus lowered its financial outlook for 2025, with consolidated net revenue expected to be between $1.475 billion to $1.51 billion, down from the prior range of $1.55 billion to $1.585 billion.
PYLARIFY Sales Decline
Sales of PYLARIFY were down 8.3% year-over-year, impacted by competitive pricing pressures and MUC-based reimbursement dynamics.
Market Challenges with PYLARIFY
Intense competitive pricing and MUC-based reimbursement challenges led to renegotiation of existing contracts and some account losses, impacting PYLARIFY volumes.
Company Guidance
During the Lantheus Second Quarter 2025 Conference Call, CEO Brian Markison announced that second-quarter results were below expectations, leading to a lowered financial outlook for the rest of 2025. PYLARIFY sales reached $251 million, a decrease of 8.3% compared to the previous year, with U.S. volumes growing 2% year-over-year and over 4% sequentially. The company reported consolidated net revenue of $378 million, down 4.1%, with a gross profit margin of 67.6%. Operational expenses increased to 27.2% of net revenue, driven by investments in growth initiatives. Lantheus adjusted its PYLARIFY sales forecast to $940 million to $965 million for the full year, with total expected revenue of $1.475 billion to $1.51 billion. Adjusted EPS guidance was revised to $5.50 to $5.70. The company also highlighted strategic steps, including the FDA's acceptance of a new PYLARIFY formulation, expected to increase batch sizes by approximately 50%, enhancing patient access and production efficiency. Additionally, a $400 million stock repurchase program was authorized, signaling confidence in long-term growth prospects.

Lantheus Financial Statement Overview

Summary
Lantheus presents a solid financial position with strong profitability and cash flow metrics. While there are concerns regarding recent revenue growth and net profit margins, the company maintains strong operational efficiency and cash flow generation. Improved leverage management is noted, though monitoring of debt levels is advisable.
Income Statement
75
Positive
Lantheus has shown strong gross profit margins consistently above 60% in recent years, indicating efficient cost management. However, the TTM data shows a slight decline in revenue growth rate and net profit margin compared to previous years, which could be a concern if the trend continues. Despite this, the company maintains a healthy EBIT and EBITDA margin, reflecting robust operational efficiency.
Balance Sheet
70
Positive
The company's debt-to-equity ratio has improved over time, indicating better leverage management, though it remains moderately high. Return on equity has been strong, suggesting effective use of shareholder funds. The equity ratio is stable, showing a balanced approach to financing assets through equity.
Cash Flow
80
Positive
Lantheus has demonstrated impressive free cash flow growth, particularly in the TTM period, which is a positive indicator of financial health. The operating cash flow to net income ratio is strong, suggesting good cash generation relative to reported earnings. The free cash flow to net income ratio is also healthy, indicating efficient conversion of earnings into cash.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.52B1.53B1.30B935.06M425.21M339.41M
Gross Profit969.38M988.29M709.54M581.70M187.69M138.76M
EBITDA457.27M515.27M491.00M81.83M-25.00M22.69M
Net Income271.00M312.44M326.66M28.07M-71.28M-13.47M
Balance Sheet
Total Assets2.12B1.98B1.65B1.32B863.78M869.82M
Cash, Cash Equivalents and Short-Term Investments695.57M912.81M713.66M415.65M98.51M79.61M
Total Debt615.49M619.44M616.95M558.07M174.76M218.40M
Total Liabilities949.29M892.33M835.26M874.11M399.35M355.62M
Stockholders Equity1.17B1.09B815.89M447.15M464.44M514.21M
Cash Flow
Free Cash Flow473.19M493.13M258.70M263.43M41.78M3.92M
Operating Cash Flow527.46M544.75M305.26M281.78M53.92M16.40M
Investing Cash Flow-370.59M-226.01M5.94M-276.55M3.68M-4.91M
Financing Cash Flow-218.42M-118.54M-13.06M311.69M-39.33M-21.86M

Lantheus Technical Analysis

Technical Analysis Sentiment
Negative
Last Price56.84
Price Trends
50DMA
70.15
Negative
100DMA
79.38
Negative
200DMA
85.57
Negative
Market Momentum
MACD
-4.10
Negative
RSI
39.36
Neutral
STOCH
48.02
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For LNTH, the sentiment is Negative. The current price of 56.84 is below the 20-day moving average (MA) of 58.77, below the 50-day MA of 70.15, and below the 200-day MA of 85.57, indicating a bearish trend. The MACD of -4.10 indicates Negative momentum. The RSI at 39.36 is Neutral, neither overbought nor oversold. The STOCH value of 48.02 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for LNTH.

Lantheus Risk Analysis

Lantheus disclosed 52 risk factors in its most recent earnings report. Lantheus reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Lantheus Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$13.57B40.3913.39%18.42%1.47%
75
Outperform
$12.02B18.0817.48%0.64%13.13%-0.47%
59
Neutral
$12.14B-19.77%4.61%-7.47%-438.39%
58
Neutral
$3.78B14.7824.71%5.75%-37.03%
58
Neutral
$20.55B-2.31%2.43%64.37%
51
Neutral
$7.83B-0.18-40.10%2.29%21.46%-2.03%
51
Neutral
$3.26B-1.32%4.77%-2.32%35.46%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LNTH
Lantheus
56.84
-52.87
-48.19%
RDY
Dr Reddy's Laboratories
14.24
-2.32
-14.01%
VTRS
Viatris
10.42
-0.93
-8.19%
NBIX
Neurocrine
138.13
14.37
11.61%
PRGO
Perrigo Company
23.89
-4.19
-14.92%
TEVA
Teva Pharmaceutical
18.05
-0.51
-2.75%

Lantheus Corporate Events

Executive/Board Changes
Lantheus CCO Amanda Morgan Takes Leave of Absence
Neutral
Aug 11, 2025

Lantheus Holdings, Inc. announced that Amanda Morgan, the Chief Commercial Officer, will take a leave of absence from the company for personal reasons, effective August 8, 2025.

Product-Related AnnouncementsM&A TransactionsStock BuybackBusiness Operations and StrategyFinancial Disclosures
Lantheus Announces FDA Acceptance of New Drug Application
Positive
Aug 6, 2025

On August 6, 2025, Lantheus announced the FDA’s acceptance of a new drug application for a new formulation of its piflufolastat F-18 imaging agent, which could significantly increase patient access. The company also reported its second-quarter financial results, highlighting a revenue of $378 million and a strategic acquisition of Life Molecular Imaging, which expands its product portfolio and market reach. Additionally, Lantheus’ board authorized a $400 million stock repurchase program, reflecting confidence in its long-term growth strategy.

Executive/Board ChangesM&A TransactionsBusiness Operations and Strategy
Lantheus Completes Acquisition of Life Molecular Imaging
Positive
Jul 22, 2025

On July 21, 2025, Lantheus completed its acquisition of Life Molecular Imaging Limited, enhancing its capabilities in Alzheimer’s disease diagnostics with the addition of Neuraceq, an F-18 PET imaging agent. The acquisition, valued at $350 million, strengthens Lantheus’s international presence and R&D capabilities. Additionally, Dr. Ludger Dinkelborg, former CEO of Life Molecular Imaging, was appointed as Lantheus’s Head of Research and Development, effective August 1, 2025, to lead various strategic areas, including Clinical Development and AI/Biomarkers Solutions.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 19, 2025