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Lantheus (LNTH)
NASDAQ:LNTH

Lantheus (LNTH) AI Stock Analysis

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LN

Lantheus

(NASDAQ:LNTH)

Rating:75Outperform
Price Target:
$91.00
▲(11.67%Upside)
Lantheus demonstrates a strong financial foundation and strategic growth opportunities through acquisitions. However, current technical indicators suggest a bearish trend, and the stock's valuation is moderate. The recent earnings call highlighted some challenges, including competitive pressures and revised guidance. These factors result in a balanced but cautious outlook for the stock.
Positive Factors
Radiopharmaceutical Opportunities
Lantheus Holdings is positioning itself to take advantage of the most promising medium- to long-term opportunities in the radiopharmaceutical field.
Revenue Growth Potential
Management continues to be excited about the prospect of returning to double-digit revenue growth anchored by flagship Pylarify and Definity with additional contributions from Neuraceq, Octevy, MK-6420, and PNT2003.
Strategic Partnerships and Expansion
Lantheus continues to secure strategic partnerships and plans to broaden contracting efforts and expand product availability.
Negative Factors
Blood-Based Diagnostics
The utility of blood-based diagnostics for Alzheimer’s disease could emerge as a headwind for Lantheus’s goal of introducing several beta amyloid- or tau-based PET tracers.
Competitive Pressure
PYLARIFY is facing competitive pressure and its net sales are down 0.5% year-over-year.
Financial Performance
Revenue came in below expectations, $257.7 million versus Street consensus of $265.1 million and analyst estimate of $262.8 million.

Lantheus (LNTH) vs. SPDR S&P 500 ETF (SPY)

Lantheus Business Overview & Revenue Model

Company DescriptionLantheus Holdings, Inc. develops, manufactures, and commercializes diagnostic and therapeutic products that assist clinicians in the diagnosis and treatment of heart, cancer, and other diseases worldwide. It provides DEFINITY, a microbubble ultrasound enhancing agent used in ultrasound exams of the heart; TechneLite, a technetium generator for nuclear medicine; Xenon-133 to assess pulmonary function; Neurolite to identify the area within the brain where blood flow has been blocked or reduced due to stroke; Cardiolite, an injectable Tc-99m-labeled imaging agent; Thallium-201 to detect cardiovascular disease; and Gallium-67 to detect various infections and cancerous tumors. The company also offers AZEDRA, a radiotherapeutic to treat adult and pediatric patients; Automated Bone Scan Index that calculates the disease burden of prostate cancer by quantifying the hotspots on bone scans; and Cobalt (Co 57), a non-pharmaceutical radiochemical; RELISTOR for opioid-induced constipation; and PYLARIFY for visualization of lymph nodes, bone, and soft tissue metastases to determine the presence or absence of recurrent and/or metastatic prostate cancer. It also develops flurpiridaz F 18 to assess blood flow to the heart; 1095, a PSMA-targeted iodine-131 labeled small molecule; LMI 1195 for neuroblastoma tumors in pediatric and adults; PYLARIFY AI, an AI-based medical device software to perform standardized quantitative assessment of PSMA PET/CT images in prostate cancer; and leronlimab, an investigational humanized monoclonal antibody. The company serves radio pharmacies, distributors, integrated delivery networks, hospitals, clinics, and group practices. It has strategic partnerships with NanoMab Technology Limited; Bausch Health Companies, Inc.; GE Healthcare Limited; Curium; Bayer AG; CytoDyn Inc.; ROTOP; FUJIFILM; Regeneron Pharmaceuticals, Inc.; and POINT Biopharma US Inc. The company was founded in 1956 and is headquartered in North Billerica, Massachusetts.
How the Company Makes MoneyLantheus makes money by selling its diagnostic imaging agents and products to hospitals, clinics, and other healthcare providers. The company's revenue is primarily generated through the commercialization of its proprietary imaging agents, which are used to enhance the diagnostic capabilities of PET and SPECT imaging technologies. Lantheus also engages in strategic partnerships and collaborations with other pharmaceutical and biotechnology companies to expand its product offerings and reach in the market. Additionally, the company's revenue streams are supported by ongoing research and development efforts that lead to the introduction of new products and enhancements to existing ones, thereby sustaining and growing its market presence.

Lantheus Earnings Call Summary

Earnings Call Date:May 07, 2025
(Q1-2025)
|
% Change Since: -22.27%|
Next Earnings Date:Jul 31, 2025
Earnings Call Sentiment Neutral
The earnings call presented a mixed outlook, with strategic acquisitions and pipeline advancements highlighting potential for future growth. However, competitive pressures on PYLARIFY, flat revenue growth, and decreased profit margins weighed on the overall sentiment. The company also lowered its full-year guidance, reflecting challenges in the current market environment.
Q1-2025 Updates
Positive Updates
Strategic Acquisitions and Divestitures
Announced the acquisition of Evergreen Theragnostics and Life Molecular Imaging, aimed at enhancing radiopharmaceutical capabilities and growth. Also announced the divestment of the SPECT business to SHINE Technologies.
Strong Product Performance
PYLARIFY sales for the first quarter were $258 million, despite a low-single-digit decline in net price. DEFINITY achieved approximately $79 million in sales, even with the return of competitive supply to the U.S. market.
Positive Pipeline Developments
MK-6240, a next-generation tau imaging agent, met its primary endpoints in two pivotal studies. The company plans to submit a new drug application to the FDA in the third quarter of 2025.
Financial Stability
Operating cash flow for the first quarter was $107.6 million, with a strong liquidity position of $938.5 million in cash and cash equivalents.
Negative Updates
PYLARIFY Competitive Pressures
Experienced competitive disruption among smaller, non-contracted sites due to changes in Medicare reimbursement, impacting growth.
Flat Revenue Growth
Consolidated net revenue for the first quarter was $372.8 million, an increase of only 0.8%. PYLARIFY contributed $257.7 million of sales, flat with the prior year.
Decreased Profit Margins
Gross profit margin for the first quarter was 67%, a decrease of 180 basis points, attributed to strategic partnership contracting initiatives and supply issues.
Lowered Full-Year Guidance
Updated full-year revenue guidance to $1.55 billion to $1.585 billion, with adjusted EPS guidance reduced to $6.60 to $6.70 from the prior guide of $7 to $7.20.
Company Guidance
During the Lantheus First Quarter 2025 Conference Call, the company provided guidance on several key metrics. They announced plans to divest their SPECT business to SHINE Technologies and highlighted two acquisitions: Evergreen Theragnostics and Life Molecular Imaging, which are expected to drive revenue growth and diversify their portfolio. The acquisitions are anticipated to enhance their radiopharmaceutical leadership and add capabilities, including infrastructure for manufacturing radiotherapeutics. The company projects the U.S. Alzheimer’s disease radiodiagnostics market could grow to more than $1.5 billion by the end of the decade and $2.5 billion by the mid-2030s. For PYLARIFY, sales for the quarter were $258 million with plans to maintain market leadership despite competitive pressures. The fiscal year 2025 guidance for PYLARIFY was updated to flat-to-low single-digit percent growth, with expectations for total net revenue to be between $1.55 billion and $1.585 billion. Adjusted EPS is expected to range from $6.60 to $6.70, down from the previous guidance of $7 to $7.20, due to strategic investments and acquisitions. The company expressed confidence in sustainable long-term growth, driven by their diversified pipeline and strategic focus.

Lantheus Financial Statement Overview

Summary
Lantheus showcases a strong financial position across all verticals. The income statement reflects impressive growth and profitability, while the balance sheet indicates financial stability and efficient leverage management. The cash flow statement highlights robust cash generation and liquidity. The company's financial performance is characterized by healthy growth, strong margins, and efficient cash management, making it well-positioned in the drug manufacturing industry.
Income Statement
92
Very Positive
Lantheus exhibits impressive growth and profitability metrics. The TTM (Trailing-Twelve-Months) shows a robust gross profit margin of 64.05% and a strong net profit margin of 16.55%. Revenue growth has been exceptional, with significant increases year-over-year. The EBIT and EBITDA margins also reflect strong operational efficiency. Overall, the company demonstrates excellent revenue growth and healthy profitability in its income statement.
Balance Sheet
85
Very Positive
Lantheus maintains a solid balance sheet with a debt-to-equity ratio of 0.53, indicating moderate leverage. The company has a strong equity position, with an equity ratio of 56.65%, which signifies financial stability. Return on equity (ROE) is also impressive at 21.84%, highlighting effective use of equity to generate profits. The balance sheet reflects a healthy financial structure with a balanced approach to debt and equity.
Cash Flow
89
Very Positive
Lantheus demonstrates strong cash flow performance. The operating cash flow to net income ratio is 2.06, indicating efficient cash generation relative to net income. Free cash flow remains robust with a modest growth rate. The free cash flow to net income ratio of 1.86 suggests effective conversion of profits into cash. Overall, the company exhibits strong cash flow management and adequate liquidity.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.54B1.53B1.30B935.06M425.21M339.41M
Gross Profit984.14M988.29M709.54M581.70M187.69M138.76M
EBITDA438.66M515.27M491.00M81.83M-25.00M22.69M
Net Income254.32M312.44M326.66M28.07M-71.28M-13.47M
Balance Sheet
Total Assets2.06B1.98B1.65B1.32B863.78M869.82M
Cash, Cash Equivalents and Short-Term Investments938.53M912.81M713.66M415.65M98.51M79.61M
Total Debt614.40M619.44M616.95M558.07M174.76M218.40M
Total Liabilities891.03M892.33M835.26M874.11M399.35M355.62M
Stockholders Equity1.16B1.09B815.89M447.15M464.44M514.21M
Cash Flow
Free Cash Flow473.00M493.13M258.70M263.43M41.78M3.92M
Operating Cash Flow525.08M544.75M305.26M281.78M53.92M16.40M
Investing Cash Flow-183.20M-226.01M5.94M-276.55M3.68M-4.91M
Financing Cash Flow-119.91M-118.54M-13.06M311.69M-39.33M-21.86M

Lantheus Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price81.49
Price Trends
50DMA
85.70
Negative
100DMA
90.08
Negative
200DMA
94.06
Negative
Market Momentum
MACD
-0.73
Negative
RSI
51.77
Neutral
STOCH
84.67
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For LNTH, the sentiment is Neutral. The current price of 81.49 is above the 20-day moving average (MA) of 79.64, below the 50-day MA of 85.70, and below the 200-day MA of 94.06, indicating a neutral trend. The MACD of -0.73 indicates Negative momentum. The RSI at 51.77 is Neutral, neither overbought nor oversold. The STOCH value of 84.67 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for LNTH.

Lantheus Risk Analysis

Lantheus disclosed 50 risk factors in its most recent earnings report. Lantheus reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Lantheus Peers Comparison

Overall Rating
UnderperformOutperform
Sector (65)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
RDRDY
77
Outperform
$12.69B18.7718.36%0.62%14.23%-0.84%
75
Outperform
$5.59B22.9124.11%12.53%-45.33%
74
Outperform
$12.41B42.5312.43%21.73%-19.24%
65
Neutral
¥345.58B10.59-2.88%2.65%11.80%-7.09%
63
Neutral
$3.65B-3.64%4.37%-4.85%-4290.31%
62
Neutral
$19.73B-18.98%3.38%-175.90%
54
Neutral
$10.57B-21.25%5.26%-6.88%-6809.78%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LNTH
Lantheus
81.49
1.49
1.86%
RDY
Dr Reddy's Laboratories
15.07
0.06
0.40%
VTRS
Viatris
9.01
-1.10
-10.88%
NBIX
Neurocrine
125.42
-14.69
-10.48%
PRGO
Perrigo Company
26.54
1.32
5.23%
TEVA
Teva Pharmaceutical
16.76
0.42
2.57%

Lantheus Corporate Events

M&A TransactionsBusiness Operations and Strategy
Lantheus Completes Acquisition of Evergreen Theragnostics
Positive
Apr 1, 2025

On April 1, 2025, Lantheus Holdings, Inc. completed its acquisition of Evergreen Theragnostics, Inc., a move that enhances Lantheus’ capabilities across the radiopharmaceutical value chain. The acquisition, initially announced on January 28, 2025, includes Evergreen’s OCTEVY, a PET diagnostic imaging agent for neuroendocrine tumors, and a portfolio of theranostic pairs, as well as Evergreen’s radioligand therapy manufacturing infrastructure. This strategic acquisition positions Lantheus to better meet market demands and drive innovation, with potential milestone payments up to $727.5 million contingent on future achievements.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 24, 2025