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Karyopharm Therapeutics (KPTI)
NASDAQ:KPTI
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Karyopharm Therapeutics (KPTI) Stock Price & Analysis

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KPTI Stock Chart & Stats


Bulls Say, Bears Say

Bulls Say
Global Expansion And ApprovalsKaryopharm announced reimbursement decisions in France and Italy, and approvals for Xpovio in Turkey, South Korea, Thailand, and Malaysia.
Market Potential And RevenueThe management estimates around $1 billion in peak revenue for myelofibrosis in the US, indicating significant market potential.
Trial Design And Regulatory SupportKaryopharm Therapeutics has made encouraging changes in the trial design for the Phase 3 SENTRY study in myelofibrosis, which are supported by the FDA.
Bears Say
Clinical TrialsTop-line endometrial Phase 3 data delayed to early 2026 on higher screen-failure rate.
Regulatory ChallengesThe company has made changes to the trial design for the pivotal Phase 3 trial evaluating Xpovio combined with Pomalyst and dexamethasone, pending regulatory feedback.
Sales PerformanceXpovio sales were up quarter-over-quarter but down year-over-year, indicating some challenges in maintaining consistent growth.
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Financials

Annual

Ownership Overview

2.34%9.47%20.26%60.20%
20.26% Other Institutional Investors
60.20% Public Companies and
Individual Investors

Risk Analysis

Main Risk Category
Tech & InnovationRisks related to the company’s reliance on technology and ability to make innovative products

Website Traffic

Sorry, No Data Available
There is no website visitor data available for this stock.
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KPTI FAQ

What was Karyopharm Therapeutics’s price range in the past 12 months?
Karyopharm Therapeutics lowest stock price was $0.62 and its highest was $1.95 in the past 12 months.
    What is Karyopharm Therapeutics’s market cap?
    Currently, no data Available
    When is Karyopharm Therapeutics’s upcoming earnings report date?
    Karyopharm Therapeutics’s upcoming earnings report date is Feb 27, 2025 which is in 92 days.
      How were Karyopharm Therapeutics’s earnings last quarter?
      Karyopharm Therapeutics released its earnings results on Nov 05, 2024. The company reported -$0.26 earnings per share for the quarter, beating the consensus estimate of -$0.263 by $0.003.
        Is Karyopharm Therapeutics overvalued?
        According to Wall Street analysts Karyopharm Therapeutics’s price is currently Undervalued. Get more investment ideas with TipRanks Premium
          Does Karyopharm Therapeutics pay dividends?
          Karyopharm Therapeutics does not currently pay dividends.
          What is Karyopharm Therapeutics’s EPS estimate?
          Karyopharm Therapeutics’s EPS estimate is -$0.25.
            How many shares outstanding does Karyopharm Therapeutics have?
            Karyopharm Therapeutics has 125,314,510 shares outstanding.
              What happened to Karyopharm Therapeutics’s price movement after its last earnings report?
              Karyopharm Therapeutics reported an EPS of -$0.26 in its last earnings report, beating expectations of -$0.263. Following the earnings report the stock price went down -9.677%.
                Which hedge fund is a major shareholder of Karyopharm Therapeutics?
                Among the largest hedge funds holding Karyopharm Therapeutics’s share is Woodline Partners LP. It holds Karyopharm Therapeutics’s shares valued at 111K.
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                  Company Description

                  Karyopharm Therapeutics

                  Karyopharm Therapeutics, Inc. is an oncology-focused pharmaceutical company dedicated to the discovery, development, and commercialization of novel first-in-class drugs directed against nuclear export and related targets for the treatment of cancer and other major diseases. Its SINE compounds function by binding with and inhibiting the nuclear export protein XPO1 (or CRM1). Karyopharm's lead compound, XPOVIOTM (selinexor), received accelerated approval from the FDA in combination with dexamethasone as a treatment for patients with heavily pretreated multiple myeloma. A Marketing Authorization Application for selinexor is also currently under review by the European Medicines Agency (EMA). In addition to single-agent and combination activity against a variety of human cancers, SINE compounds have also shown biological activity in models of neurodegeneration, inflammation, autoimmune disease, certain viruses and wound-healing. Karyopharm has several investigational programs in clinical or preclinical development. The company was founded by Joseph Araujo, Ronald A. DePinho, Pamela A Silver, Giulio Draetta, Michael G. Kauffman and Sharon Shacham on December 22, 2008 and is headquartered in Newton, MA.
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                  KPTI Company Deck

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                  KPTI Earnings Call

                  Q3 2024
                  0:00 / 0:00
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                  KPTI Stock 12 Month Forecast

                  Average Price Target

                  $4.50
                  ▲(413.82% Upside)
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                  Best Analysts Covering KPTI

                  1 Year
                  Colleen M. KusyRobert W. Baird
                  1 Year Success Rate
                  3/27 ratings generated profit
                  11%
                  1 Year Average Return
                  -40.61%
                  reiterated a buy rating 22 days ago
                  Copying Colleen M. Kusy's trades and holding each position for 1 Year would result in 11.11% of your transactions generating a profit, with an average return of -40.61% per trade.
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