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Karyopharm Therapeutics (KPTI)
NASDAQ:KPTI
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KPTI Stock Chart & Stats
Day’s Range― - ―
52-Week Range$0.58 - $1.95
Previous CloseN/A
Volume220.82K
Average Volume (3M)1.16M
Market Cap
$88.12M
Enterprise Value$164.46M
Total Cash (Recent Filing)$129.55M
Total Debt (Recent Filing)N/A
Price to Earnings (P/E)―
Beta1.35
Next Earnings
Feb 27, 2025EPS Estimate
-0.26Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-1.14
Shares Outstanding126,190,740
10 Day Avg. Volume844,118
30 Day Avg. Volume1,164,718
Standard Deviation0.19
R-Squared0.00038
Alpha-0.04
Financial Highlights & Ratios
PEG RatioN/A
Price to Book (P/B)N/A
Price to Sales (P/S)0.54
Price to Cash Flow (P/CF)-1.00
P/FCF Ratio0.00
Enterprise Value/Market Cap1.87
Enterprise Value/Revenue1.11
Enterprise Value/Gross Profit1.17
Enterprise Value/Ebitda-2.70
Forecast
1Y Price Target
$4.50Price Target Upside542.86% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering6
Karyopharm Therapeutics News
PremiumCompany Announcements
Karyopharm Appoints Lori Macomber as New CFO
PremiumCompany Announcements
Karyopharm Engages with FDA on Cancer Trial Plans
PremiumCompany Announcements
Karyopharm Therapeutics Appoints New Chief Accounting Officer
Bulls Say, Bears Say
Bulls Say
Market PotentialKaryopharm estimates a peak revenue opportunity of $1 billion for Xpovio in myelofibrosis, highlighting its significant market potential.
Regulatory ApprovalsXpovio has FDA Fast Track Designation for the treatment of patients with myelofibrosis, including primary MF, post-essential thrombocythemia MF, and post-polycythemia vera MF.
Trial Design EnhancementsEncouraging changes in the trial design for the Phase 3 SENTRY study in myelofibrosis, supported by the FDA, are expected to modestly improve its likelihood of success.
Bears Say
Clinical TrialsTop-line endometrial Phase 3 data delayed to early 2026 on higher screen-failure rate.
Financial PerformanceXpovio net product revenue was impacted by higher gross-to-net adjustments, driven primarily by increased 340B discounts and Medicare rebates.
Sales GrowthXpovio sales were up quarter-over-quarter but down year-over-year, indicating some challenges in maintaining consistent growth.
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Ownership Overview
2.32% Insiders
9.25% Mutual Funds
0.02% Other Institutional Investors
80.74% Public Companies and Individual Investors
Risk Analysis
Main Risk Category
Tech & InnovationRisks related to the company’s reliance on technology and ability to make innovative products
Website Traffic
Sorry, No Data AvailableThere is no website visitor data available for this stock.
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KPTI FAQ
What was Karyopharm Therapeutics’s price range in the past 12 months?
Karyopharm Therapeutics lowest stock price was $0.58 and its highest was $1.95 in the past 12 months.
What is Karyopharm Therapeutics’s market cap?
Karyopharm Therapeutics’s market cap is $88.12M.
When is Karyopharm Therapeutics’s upcoming earnings report date?
Karyopharm Therapeutics’s upcoming earnings report date is Feb 27, 2025 which is in 40 days.
How were Karyopharm Therapeutics’s earnings last quarter?
Karyopharm Therapeutics released its earnings results on Nov 05, 2024. The company reported -$0.26 earnings per share for the quarter, beating the consensus estimate of -$0.263 by $0.003.
Is Karyopharm Therapeutics overvalued?
According to Wall Street analysts Karyopharm Therapeutics’s price is currently Undervalued.
Does Karyopharm Therapeutics pay dividends?
Karyopharm Therapeutics does not currently pay dividends.
What is Karyopharm Therapeutics’s EPS estimate?
Karyopharm Therapeutics’s EPS estimate is -0.26.
How many shares outstanding does Karyopharm Therapeutics have?
Karyopharm Therapeutics has 126,190,740 shares outstanding.
What happened to Karyopharm Therapeutics’s price movement after its last earnings report?
Karyopharm Therapeutics reported an EPS of -$0.26 in its last earnings report, beating expectations of -$0.263. Following the earnings report the stock price went down -9.677%.
Which hedge fund is a major shareholder of Karyopharm Therapeutics?
Among the largest hedge funds holding Karyopharm Therapeutics’s share is Woodline Partners LP. It holds Karyopharm Therapeutics’s shares valued at 111K.
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Karyopharm Therapeutics Stock Smart Score
Unlock Smart Score
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Analyst Consensus
Strong Buy
Average Price Target:
$4.50 (542.86% Upside)
$4.50 (542.86% Upside)
Crowd Wisdom
Neutral
Last 7 Days ▲ 0.7%
Last 30 Days ▲ 0.2%
Last 30 Days ▲ 0.2%
News Sentiment
Very Bullish
Bullish news 100%
Bearish news 0%
Bearish news 0%
Technicals
SMA
Negative
20 days / 200 days
Momentum
-3.59%
12-Months-Change
Fundamentals
Return on Equity
54.80%
Trailing 12-Months
Asset Growth
-29.81%
Trailing 12-Months
Company Description
Karyopharm Therapeutics
Karyopharm Therapeutics, Inc. is an oncology-focused pharmaceutical company dedicated to the discovery, development, and commercialization of novel first-in-class drugs directed against nuclear export and related targets for the treatment of cancer and other major diseases. Its SINE compounds function by binding with and inhibiting the nuclear export protein XPO1 (or CRM1). Karyopharm's lead compound, XPOVIOTM (selinexor), received accelerated approval from the FDA in combination with dexamethasone as a treatment for patients with heavily pretreated multiple myeloma. A Marketing Authorization Application for selinexor is also currently under review by the European Medicines Agency (EMA). In addition to single-agent and combination activity against a variety of human cancers, SINE compounds have also shown biological activity in models of neurodegeneration, inflammation, autoimmune disease, certain viruses and wound-healing. Karyopharm has several investigational programs in clinical or preclinical development. The company was founded by Joseph Araujo, Ronald A. DePinho, Pamela A Silver, Giulio Draetta, Michael G. Kauffman and Sharon Shacham on December 22, 2008 and is headquartered in Newton, MA.
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KPTI Company Deck
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KPTI Earnings Call
Q3 2024
0:00 / 0:00
Earnings Call Sentiment|Positive
The earnings call highlighted significant advancements and opportunities in Karyopharm's clinical trials and market potential, alongside successful cost management and revenue growth. However, the company faces challenges with increased discounts affecting net revenue and a decrease in cash reserves.Read More>---
KPTI Stock 12 Month Forecast
Average Price Target
$4.50
▲(542.86% Upside)
Technical Analysis
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Best Analysts Covering KPTI
1 Year
1 Year Success Rate
2/27 ratings generated profit
1 Year Average Return
-46.20%
reiterated a buy rating 3 days ago
Copying Edward White's trades and holding each position for 1 Year would result in 7.41% of your transactions generating a profit, with an average return of -46.20% per trade.
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