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Lantern Pharma, Inc. (LTRN)
:LTRN
US Market
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Lantern Pharma (LTRN) AI Stock Analysis

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LTRN

Lantern Pharma

(NASDAQ:LTRN)

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Neutral 45 (OpenAI - 4o)
Rating:45Neutral
Price Target:
Lantern Pharma is innovating with AI in oncology, achieving key clinical and regulatory milestones. However, the financial outlook is challenging due to zero revenue and cash flow concerns, necessitating additional funding. Technicals are stable but show potential volatility.
Positive Factors
AI Integration
The integration of AI and machine learning into drug development enhances efficiency and precision, potentially reducing costs and accelerating timelines, which is a significant competitive advantage in the biotechnology sector.
Regulatory Achievements
FDA Fast Track designations can expedite the development and review process, potentially bringing drugs to market faster, which is crucial for addressing unmet medical needs and enhancing future revenue potential.
Strategic Expansion
Expanding clinical trials geographically can increase patient enrollment and diversify market presence, enhancing the company's ability to capture global market opportunities and improve clinical trial outcomes.
Negative Factors
Zero Revenue
The lack of revenue generation highlights the company's reliance on external funding and partnerships, posing a risk to financial sustainability and limiting its ability to self-fund operations and growth initiatives.
Increased Operating Loss
Rising operational losses without corresponding revenue increases strain financial resources, necessitating additional funding and potentially diluting shareholder value if equity financing is pursued.
Funding Needs
The need for significant external funding highlights potential liquidity issues and the risk of financial instability, which could impact the company's ability to sustain operations and invest in growth.

Lantern Pharma (LTRN) vs. SPDR S&P 500 ETF (SPY)

Lantern Pharma Business Overview & Revenue Model

Company DescriptionLantern Pharma Inc., a clinical stage biotechnology company, focuses on artificial intelligence, machine learning, and genomic data to streamline the drug development process. Its advanced drug candidate is LP-100, which is in phase II clinical trials to treat metastatic, castration-resistant, and prostate cancer. The company also develops LP-300 as a combination therapy for non or never-smokers with non-small cell lung cancer adenocarcinoma. In addition, its preclinical development drug candidate is LP-184, an alkylating agent that damages DNA in cancer cells that overexpress certain biomarkers or that harbor mutations in DNA repair pathways. Further, the company operates ADC program, an antibody drug conjugate therapeutic approach for cancer treatment. Additionally, the company's artificial intelligence platform RADR uses big data analytics and machine learning for combining molecular data. The company was incorporated in 2013 and is headquartered in Dallas, Texas.
How the Company Makes MoneyLantern Pharma generates revenue primarily through the development and commercialization of its drug candidates. The company uses its proprietary RADR platform to identify biomarkers and genetic signatures that can predict patient response to its drug candidates, thereby reducing time and cost associated with drug development. Revenue streams include out-licensing partnerships, collaborations with pharmaceutical companies, and potentially, future sales of approved drugs. These partnerships often involve milestone payments, royalties, and shared development costs, which are significant contributors to the company's earnings. As Lantern Pharma advances its drug pipeline and secures additional partnerships, these factors are expected to drive financial growth.

Lantern Pharma Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 05, 2026
Earnings Call Sentiment Positive
The earnings call highlighted significant achievements in clinical trial results and regulatory progress, along with advancements in AI platform commercialization. Financial stability was noted, but there is a requirement for additional funding in the near future.
Q3-2025 Updates
Positive Updates
Successful LP-184 Phase Ia Clinical Trial
The LP-184 Phase Ia clinical trial successfully achieved all primary endpoints, demonstrating a 48% clinical benefit rate in evaluable cancer patients who received doses at or above the therapeutic threshold.
Regulatory Progress with FDA
Completed a productive FDA Type C meeting for Starlight Therapeutics, gaining clear guidance for a planned pediatric CNS cancer trial targeting ATRT.
Expansion of AI Platform, RADR
Demonstrated commercial readiness of the RADR AI platform with several deployable, scalable modules, indicating potential for significant revenue generation.
Financial Stability
As of September 30, 2025, Lantern Pharma had $12.4 million in cash, cash equivalents, and marketable securities, providing a runway into Q3 2026.
Positive Preliminary Data from LP-300 HARMONIC Trial
Preliminary data showed an 86% clinical benefit rate, with one patient demonstrating a durable complete response lasting nearly two years.
AI Platform Commercial Opportunities
Showcased commercial readiness of AI modules at the AI Biology and Medicine Symposium, highlighting potential revenue streams from licensing to biopharma partners.
Negative Updates
Decrease in R&D Expenses
R&D expenses decreased to $2.4 million from $3.7 million year-over-year, primarily due to reductions in research study and materials expenses, consulting, and payroll.
Need for Additional Funding
Acknowledged the need for substantial additional funding in the near future to continue operations and development.
Company Guidance
During Lantern Pharma's third quarter 2025 earnings call, the company highlighted several key metrics and milestones, signaling a transformative period. The LP-184 Phase Ia clinical trial achieved all primary endpoints with a 48% clinical benefit rate in cancer patients, particularly those with DNA damage repair mutations. The company also advanced its AI platform, RADR, and outlined future plans for its CNS-focused subsidiary, Starlight Therapeutics. Financially, Lantern reported a net loss of $4.2 million, or $0.39 per share, for the quarter, with $12.4 million in cash and equivalents, providing runway until the third quarter of 2026. The company also discussed its strategic approach to drug development, leveraging AI to identify high-probability success areas, and detailed upcoming clinical trials targeting a combined market opportunity exceeding $7 billion.

Lantern Pharma Financial Statement Overview

Summary
Lantern Pharma faces significant financial challenges, with zero revenue and increasing operational losses. Despite a strong balance sheet with low debt, the negative cash flow situation raises concerns about long-term viability and the need for additional financing.
Income Statement
20
Very Negative
Lantern Pharma has consistently reported zero revenue, indicating a pre-revenue stage or significant challenges in generating sales. The company's net losses have increased substantially over the years, reflecting mounting operational challenges. The EBIT and EBITDA margins are negative due to high operational expenses without corresponding revenue, undermining profitability prospects.
Balance Sheet
60
Neutral
The company maintains a strong equity position relative to its assets, with a high equity ratio, reflecting financial stability. The debt-to-equity ratio is low, indicating minimal reliance on debt financing, which reduces financial risk. However, the consistent increase in liabilities and decreasing cash reserves could affect future liquidity and operational capacity.
Cash Flow
30
Negative
Lantern Pharma exhibits negative operating and free cash flows, indicating cash burn without revenue inflow. Despite substantial financing inflows in prior years, the inability to generate positive cash flows from operations is concerning. The lack of free cash flow growth highlights potential sustainability challenges.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-59.90K0.00-174.84K0.000.000.00
EBITDA-19.41M-22.20M-15.79M-14.42M-12.58M-5.90M
Net Income-18.92M-20.78M-15.96M-14.26M-12.36M-5.91M
Balance Sheet
Total Assets13.63M25.57M43.65M58.84M73.95M20.36M
Cash, Cash Equivalents and Short-Term Investments12.36M24.01M41.30M55.20M70.73M19.23M
Total Debt93.95K243.66K234.47K52.89K204.95K108.50K
Total Liabilities4.04M4.38M2.74M2.80M2.38M660.84K
Stockholders Equity9.59M21.19M40.91M56.04M71.57M19.70M
Cash Flow
Free Cash Flow-16.86M-17.83M-14.37M-12.80M-10.61M-5.67M
Operating Cash Flow-16.86M-17.81M-14.35M-12.77M-10.59M-5.65M
Investing Cash Flow16.21M3.37M-930.21K179.27K-19.53M-16.14K
Financing Cash Flow971.78K66.71K-500.00K-2.18M63.42M23.66M

Lantern Pharma Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price3.02
Price Trends
50DMA
3.93
Negative
100DMA
4.09
Negative
200DMA
3.83
Negative
Market Momentum
MACD
-0.13
Negative
RSI
54.98
Neutral
STOCH
82.51
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For LTRN, the sentiment is Neutral. The current price of 3.02 is below the 20-day moving average (MA) of 3.50, below the 50-day MA of 3.93, and below the 200-day MA of 3.83, indicating a neutral trend. The MACD of -0.13 indicates Negative momentum. The RSI at 54.98 is Neutral, neither overbought nor oversold. The STOCH value of 82.51 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for LTRN.

Lantern Pharma Risk Analysis

Lantern Pharma disclosed 72 risk factors in its most recent earnings report. Lantern Pharma reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Lantern Pharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$32.48M-146.61%37.89%
45
Neutral
$42.50M-104.58%1.18%
44
Neutral
$36.29M-1.86-2691.06%44.50%
38
Underperform
$42.00M-94.31%-53.18%
35
Underperform
$45.16M-2287.74%-60.01%
35
Underperform
$50.01M-0.74-100.00%32.37%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LTRN
Lantern Pharma
3.80
0.59
18.38%
SKYE
Skye Bioscience
1.31
-3.18
-70.82%
BCAB
BioAtla
0.85
-0.83
-49.40%
RNXT
RenovoRx
0.89
-0.38
-30.24%
MAIA
MAIA Biotechnology, Inc.
1.06
-1.15
-52.04%
MDCX
Medicus Pharma Ltd
2.05
-0.65
-24.07%

Lantern Pharma Corporate Events

Business Operations and StrategyFinancial Disclosures
Lantern Pharma Reports Q4 2024 Financial Results and AI Progress
Positive
Mar 27, 2025

On March 27, 2025, Lantern Pharma announced its financial results for the fourth quarter and full year ended December 31, 2024, alongside updates on its AI-driven drug candidates and operational progress. The company reported significant advancements in its clinical programs, including the HARMONIC™ trial for LP-300, which showed promising results in never-smoker NSCLC patients, and the continued progress of LP-184 and LP-284 in clinical trials. Lantern Pharma also highlighted its innovative AI capabilities, such as the RADR® platform surpassing 100 billion oncology-specific data points and the development of an AI-powered ADC module, which could significantly reduce development timelines and costs.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 02, 2025