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OKYO Pharma Limited Sponsored ADR (OKYO)
NASDAQ:OKYO
US Market

OKYO Pharma Limited Sponsored ADR (OKYO) AI Stock Analysis

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OKYO

OKYO Pharma Limited Sponsored ADR

(NASDAQ:OKYO)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$2.50
▲(2.88% Upside)
The score is held back primarily by weak fundamentals (no revenue, ongoing losses, negative free cash flow, and negative equity), despite meaningful improvement in 2025 cash burn and zero debt. Technicals are supportive with price above key moving averages and positive momentum indicators, but valuation remains constrained by negative earnings and no dividend.
Positive Factors
Clinical Progress (Urcosimod Phase 2)
Positive Phase 2 results demonstrating both symptom relief and corneal nerve improvement materially de-risk the lead program. This supports advancement to a larger multicenter Phase 2 in early 2026, helps attract partners or funding, and strengthens long-term commercial prospects in a space with unmet need.
Leadership with Ophthalmology Commercial Experience
Appointing an industry veteran with a track record launching ophthalmology blockbusters brings durable commercial and regulatory know-how. This increases the company's ability to design pivotal programs, negotiate partnerships, and execute go-to-market planning if trials succeed, improving long-term execution risk.
Improved Cash Burn and Zero Debt
Meaningful reduction in operating cash burn alongside no debt improves runway flexibility and reduces near-term insolvency pressure. Sustained cost discipline enhances the company’s ability to fund additional clinical work or negotiate less dilutive partnership deals over the coming quarters.
Negative Factors
Pre-revenue with Persistent Net Losses
The company remains pre-revenue and loss-making, meaning it lacks internal cash generation to fund development. Continued negative earnings create structural dependence on external capital, increasing dilution risk and constraining long-term autonomy unless a commercial product emerges.
Negative Stockholders' Equity
A negative equity position is a persistent solvency weakness that limits financial flexibility and borrowing capacity despite zero debt. Over time this structural balance-sheet impairment can hinder partnerships, raise covenant or counterparty concerns, and increase financing costs.
Ongoing Negative Free Cash Flow and Funding Need
Consistent negative free cash flow reflects an R&D-intensive model that requires recurrent capital raises to progress clinical programs. Even with improved burn, the structural need for external funding elevates dilution and execution risk, potentially delaying programs if financing is constrained.

OKYO Pharma Limited Sponsored ADR (OKYO) vs. SPDR S&P 500 ETF (SPY)

OKYO Pharma Limited Sponsored ADR Business Overview & Revenue Model

Company DescriptionOKYO Pharma Limited, a preclinical biopharmaceutical company, engages in developing therapeutics for patients suffering from inflammatory eye diseases and ocular pain in the United Kingdom. Its lead product includes OK-101 for the treatment of dry eye disease. The company is also developing OK-201, a bovine adrenal medulla, lipidated-peptide preclinical analogue candidate for the treatment of neuropathic ocular pain. OKYO Pharma Limited was incorporated in 2007 and is headquartered in London, the United Kingdom.
How the Company Makes MoneyOKYO Pharma Limited generates revenue primarily through the development and potential commercialization of its drug candidates. The company makes money by advancing its therapeutic products through clinical trials and ultimately obtaining regulatory approvals to market them. Revenue streams may include licensing agreements with larger pharmaceutical companies, milestone payments, and royalties from any successful commercialization of its treatments. Additionally, OKYO may engage in strategic partnerships or collaborations that provide funding and resources to support its research and development efforts.

OKYO Pharma Limited Sponsored ADR Financial Statement Overview

Summary
OKYO Pharma Limited faces significant financial challenges with no revenue generation and negative equity, which presents a high financial risk. Persistent cash outflows due to ongoing R&D investments without profitability improvements remain key concerns.
Income Statement
OKYO Pharma Limited has shown no total revenue over the past years, reflecting the challenges in generating sales typical in the biotechnology industry. Net income remains negative, indicating ongoing operational and developmental expenses without offsetting revenue.
Balance Sheet
The balance sheet indicates a concerning negative stockholders' equity, which is a risk factor for financial stability. The total liabilities exceed total assets, which may affect the company's ability to raise capital. The debt-to-equity ratio cannot be calculated due to negative equity, further highlighting financial risk.
Cash Flow
OKYO's cash flow is characterized by negative operating cash flow and free cash flow, suggesting significant cash burn typical for R&D-focused biotech firms. However, the company has managed to secure financing inflows, which partially mitigates cash flow concerns.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-2.56K-2.56K-3.87K-3.80K-2.42K-13.09K
EBITDA-7.08M-7.08M-15.75M-13.18M-6.21M-3.35M
Net Income-4.71M-4.71M-16.83M-13.27M-5.43M-3.35M
Balance Sheet
Total Assets3.68M3.68M1.54M5.20M4.30M7.09M
Cash, Cash Equivalents and Short-Term Investments1.56M1.56M826.85K4.05M2.70M6.89M
Total Debt0.000.000.002.22M0.0098.76K
Total Liabilities9.23M9.23M7.42M7.26M1.35M1.77M
Stockholders Equity-5.55M-5.55M-5.88M-2.05M2.95M5.32M
Cash Flow
Free Cash Flow-1.81M-1.81M-9.49M-7.70M-5.47M-1.61M
Operating Cash Flow-1.81M-1.81M-9.49M-7.70M-5.47M-1.60M
Investing Cash Flow-1.21K-1.21K0.00-5.92K-1.67K-18.11K
Financing Cash Flow2.10M2.66M6.21M9.32M2.15M7.83M

OKYO Pharma Limited Sponsored ADR Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2.43
Price Trends
50DMA
2.18
Positive
100DMA
2.19
Positive
200DMA
2.12
Positive
Market Momentum
MACD
0.05
Negative
RSI
57.98
Neutral
STOCH
56.80
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OKYO, the sentiment is Positive. The current price of 2.43 is above the 20-day moving average (MA) of 2.06, above the 50-day MA of 2.18, and above the 200-day MA of 2.12, indicating a bullish trend. The MACD of 0.05 indicates Negative momentum. The RSI at 57.98 is Neutral, neither overbought nor oversold. The STOCH value of 56.80 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for OKYO.

OKYO Pharma Limited Sponsored ADR Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$343.32M-7.43-47.85%-19.69%
52
Neutral
$84.62M-17.05
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$120.54M-0.84-85.93%-60.99%
48
Neutral
$66.96M-1.05-76.44%-10.03%11.06%
45
Neutral
$94.04M-0.56-209.00%40.22%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OKYO
OKYO Pharma Limited Sponsored ADR
2.32
1.19
105.31%
BMEA
Biomea Fusion
1.34
-2.64
-66.33%
ABOS
Acumen Pharmaceuticals
1.86
0.21
12.73%
TCRX
TScan Therapeutics
1.18
-1.59
-57.40%
ZURA
Zura Bio
5.26
3.10
143.52%

OKYO Pharma Limited Sponsored ADR Corporate Events

OKYO Pharma Names Ophthalmology Veteran Robert J. Dempsey as CEO to Drive Next Growth Phase
Jan 5, 2026

On January 5, 2026, OKYO Pharma appointed ophthalmology industry veteran Robert J. Dempsey as Chief Executive Officer and an executive board member, while former CEO Gary S. Jacob, Ph.D., moved into the role of Chief Development Officer and remained on the board. The board-approved leadership transition, effective immediately, is designed to maintain strategic continuity while sharpening OKYO’s commercial and development focus as it advances its flagship drug urcosimod for neuropathic corneal pain and other ocular inflammatory disorders; Dempsey’s track record in launching and commercializing blockbuster eye therapies such as Xiidra and Restasis is expected to strengthen OKYO’s positioning in the ophthalmology market and support the company’s next phase of growth around its planned larger Phase 2 NCP program.

The most recent analyst rating on (OKYO) stock is a Hold with a $2.00 price target. To see the full list of analyst forecasts on OKYO Pharma Limited Sponsored ADR stock, see the OKYO Stock Forecast page.

OKYO Pharma Rings Nasdaq Opening Bell as Urcosimod Advances After Positive Phase 2 NCP Data
Dec 19, 2025

On December 19, 2025, OKYO Pharma marked its progress in developing treatments for neuropathic corneal pain by having Executive Chairman and Founder Gabriele Cerrone and the management team ring the Opening Bell at the Nasdaq MarketSite in Times Square, New York. The ceremony highlighted the company’s clinical advances with its lead candidate urcosimod, which recently delivered positive Phase 2 results in NCP, demonstrating favorable corneal nerve outcomes and pain reduction in patients facing a debilitating condition without approved therapies. OKYO is leveraging this momentum as it prepares a larger, multicenter Phase 2 trial of urcosimod in NCP, planned to begin in the first quarter of 2026, underscoring its bid to strengthen its position in ocular pain therapeutics and signaling potential long-term implications for patients and investors if subsequent trials confirm these early efficacy signals.

The most recent analyst rating on (OKYO) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on OKYO Pharma Limited Sponsored ADR stock, see the OKYO Stock Forecast page.

OKYO Pharma Chairman Increases Stake Amid Promising Drug Trials
Dec 15, 2025

On December 15, 2025, OKYO Pharma Limited announced that Panetta Partners Limited, associated with Executive Chairman Gabriele Cerrone, acquired 24,551 of the company’s ordinary shares on NASDAQ, increasing Cerrone’s total holding to 10,516,297 shares. This acquisition highlights the confidence in OKYO’s ongoing development of urcosimod, a promising treatment for neuropathic corneal pain and dry eye disease, which has shown significant results in Phase 2 trials, potentially enhancing the company’s market position in ophthalmology.

The most recent analyst rating on (OKYO) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on OKYO Pharma Limited Sponsored ADR stock, see the OKYO Stock Forecast page.

OKYO Pharma Reports Positive Phase 2 Results for Urcosimod in Neuropathic Corneal Pain
Dec 11, 2025

On December 11, 2025, OKYO Pharma Limited announced new analyses from a Phase 2 clinical trial of urcosimod, showing positive results in treating neuropathic corneal pain (NCP). The trial demonstrated that patients treated with 0.05% urcosimod experienced not only a reduction in pain but also favorable changes in corneal nerve structure, unlike the placebo group. These findings suggest urcosimod’s potential as a first-in-class therapeutic approach for NCP, highlighting its promise in restoring corneal nerve health and supporting further development.

The most recent analyst rating on (OKYO) stock is a Buy with a $5.00 price target. To see the full list of analyst forecasts on OKYO Pharma Limited Sponsored ADR stock, see the OKYO Stock Forecast page.

OKYO Pharma’s Chairman Increases Stake Amidst Phase 2 Trial Completion
Dec 3, 2025

On December 3, 2025, OKYO Pharma Limited announced that Panetta Partners Limited, associated with Executive Chairman Gabriele Cerrone, acquired 27,051 of the company’s ordinary shares on NASDAQ, increasing his total holdings to 10,491,746 shares. This acquisition underscores confidence in OKYO’s strategic direction, particularly as it advances urcosimod, which recently completed a Phase 2 trial for neuropathic corneal pain, potentially strengthening its market position in the ophthalmology sector.

The most recent analyst rating on (OKYO) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on OKYO Pharma Limited Sponsored ADR stock, see the OKYO Stock Forecast page.

OKYO Pharma’s Chairman Increases Stake with Recent Share Acquisition
Nov 21, 2025

On November 21, 2025, OKYO Pharma Limited announced that Panetta Partners Limited, associated with Executive Chairman Gabriele Cerrone, acquired 82,018 ordinary shares of the company on NASDAQ, increasing his total holding to 10,464,695 shares. This acquisition signifies a strong vote of confidence from the leadership in the company’s future prospects, particularly as OKYO has recently completed a Phase 2 trial of urcosimod for treating neuropathic corneal pain, a condition lacking FDA-approved therapies.

The most recent analyst rating on (OKYO) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on OKYO Pharma Limited Sponsored ADR stock, see the OKYO Stock Forecast page.

OKYO Pharma to Present Urcosimod at OIS XV
Nov 18, 2025

On November 18, 2025, OKYO Pharma Limited announced that its CEO, Gary S. Jacob, will present at the Ophthalmology Innovation Summit (OIS) XV in San Diego, scheduled for November 22, 2025. The presentation will focus on urcosimod, OKYO’s lead investigational drug for treating neuropathic corneal pain (NCP), a condition with no FDA-approved therapies. The announcement highlights OKYO’s recent positive Phase 2 trial results and its plans for a larger clinical trial, underscoring the company’s commitment to addressing unmet medical needs in the ophthalmic field.

The most recent analyst rating on (OKYO) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on OKYO Pharma Limited Sponsored ADR stock, see the OKYO Stock Forecast page.

OKYO Pharma to Present at BIO-Europe 2025 Highlighting Urcosimod Progress
Oct 29, 2025

On October 29, 2025, OKYO Pharma announced that its CEO, Dr. Gary S. Jacob, will present at the 33rd Annual BIO-Europe partnering conference in Vienna, Austria, scheduled for November 3-5, 2025. The presentation will highlight OKYO’s lead investigational candidate, urcosimod, and provide updates on its recently completed Phase 2 clinical trial for neuropathic corneal pain. This event represents a significant opportunity for OKYO to engage with global leaders and potential collaborators, potentially enhancing its industry positioning and accelerating the clinical development of urcosimod.

The most recent analyst rating on (OKYO) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on OKYO Pharma Limited Sponsored ADR stock, see the OKYO Stock Forecast page.

OKYO Pharma’s Chairman Increases Stake with New Share Acquisition
Oct 16, 2025

On October 16, 2025, OKYO Pharma Limited announced that Panetta Partners Limited, in which Executive Chairman Gabriele Cerrone has a beneficial interest, acquired 210,000 of the company’s ordinary shares on NASDAQ, increasing his total holding to 10,382,677 shares. This acquisition underscores confidence in the company’s strategic direction and its ongoing development of urcosimod, which has shown promising results in Phase 2 trials for treating neuropathic corneal pain and dry eye disease.

The most recent analyst rating on (OKYO) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on OKYO Pharma Limited Sponsored ADR stock, see the OKYO Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 06, 2026