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Biomea Fusion (BMEA)
NASDAQ:BMEA
US Market
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Biomea Fusion (BMEA) AI Stock Analysis

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BMEA

Biomea Fusion

(NASDAQ:BMEA)

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Neutral 48 (OpenAI - 5.2)
Rating:48Neutral
Price Target:
$1.00
▼(-54.75% Downside)
Action:Reiterated
Date:05/14/26
The score is primarily held back by weak financial fundamentals (no revenue, ongoing losses and cash burn, and a shrinking equity base), with additional pressure from negative/soft technical momentum. Offsetting this, recent corporate updates include encouraging Phase 2 T1D data and clear next-study plans, supporting a higher outlook than the financials alone would imply.
Positive Factors
Differentiated R&D platform
Biomea's focus on covalent small-molecule design aims for durable target engagement versus reversible agents. That scientific differentiation can provide sustained pharmacology, a harder-to-replicate mechanism and a platform advantage that supports pipeline value and partnerships across multiple indications over 2-6 months.
Negative Factors
No product revenue
As a clinical-stage company with zero product revenue, Biomea relies on external financing or partnerships to fund operations. Lack of recurring income creates persistent funding dependency, increasing execution risk and the potential for program delays or scope reductions absent new capital.
Read all positive and negative factors
Positive Factors
Negative Factors
Differentiated R&D platform
Biomea's focus on covalent small-molecule design aims for durable target engagement versus reversible agents. That scientific differentiation can provide sustained pharmacology, a harder-to-replicate mechanism and a platform advantage that supports pipeline value and partnerships across multiple indications over 2-6 months.
Read all positive factors

Biomea Fusion (BMEA) vs. SPDR S&P 500 ETF (SPY)

Biomea Fusion Business Overview & Revenue Model

Company Description
Biomea Fusion, Inc., a biopharmaceutical company, focuses on the discovery and development of covalent small molecule drugs to treat patients with genetically defined cancers and metabolic diseases. Its lead product candidate is BMF-219, an orally...
How the Company Makes Money
Biomea Fusion’s revenue model is primarily based on (1) collaboration and licensing arrangements, if and when in place, and (2) financing activities (e.g., equity offerings) used to fund operations while products are in development. As a clinical-...

Biomea Fusion Financial Statement Overview

Summary
Early-stage, pre-commercial profile with zero revenue and sustained losses/cash burn. Positives include meaningfully improving net loss and operating cash outflow versus 2024 and low leverage, but equity/assets have eroded sharply, increasing funding risk.
Income Statement
18
Very Negative
Balance Sheet
50
Neutral
Cash Flow
22
Negative
BreakdownTTMDec 2025Mar 2025Mar 2024Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-593.00K-1.41M0.000.000.000.00
EBITDA-62.81M-79.90M-142.32M-124.62M-82.94M-41.42M
Net Income-44.95M-61.80M-138.43M-117.25M-81.83M-41.57M
Balance Sheet
Total Assets46.38M58.57M79.94M199.93M129.31M185.71M
Cash, Cash Equivalents and Short-Term Investments44.69M55.81M58.28M176.87M113.05M173.52M
Total Debt1.24M1.59M8.77M10.30M2.29M2.85M
Total Liabilities27.67M29.02M28.36M30.69M20.77M6.92M
Stockholders Equity18.72M29.55M51.57M169.24M108.54M178.78M
Cash Flow
Free Cash Flow-56.25M-70.37M-120.26M-99.96M-63.45M-38.61M
Operating Cash Flow-56.25M-70.37M-119.89M-96.59M-62.42M-35.44M
Investing Cash Flow550.00K0.00-362.00K-2.22M27.34M-33.35M
Financing Cash Flow64.53M67.90M1.67M163.80M1.24M153.19M

Biomea Fusion Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.21
Price Trends
50DMA
1.54
Negative
100DMA
1.43
Negative
200DMA
1.51
Negative
Market Momentum
MACD
-0.09
Positive
RSI
33.79
Neutral
STOCH
4.45
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BMEA, the sentiment is Negative. The current price of 2.21 is above the 20-day moving average (MA) of 1.53, above the 50-day MA of 1.54, and above the 200-day MA of 1.51, indicating a bearish trend. The MACD of -0.09 indicates Positive momentum. The RSI at 33.79 is Neutral, neither overbought nor oversold. The STOCH value of 4.45 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BMEA.

Biomea Fusion Risk Analysis

Biomea Fusion disclosed 91 risk factors in its most recent earnings report. Biomea Fusion reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Biomea Fusion Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$446.07M-4.45-22.51%1199.64%30.81%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$96.16M-2.23-196.72%74.83%
48
Neutral
$131.17M0.81-23.05%24.46%
48
Neutral
$41.68M-1.18-84.91%-40.23%
47
Neutral
$100.78M-15.27-666.47%-100.00%46.40%
46
Neutral
$92.37M-1.40-26.58%-1.44%11.50%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BMEA
Biomea Fusion
1.33
-0.12
-8.28%
AGEN
Agenus
3.15
-0.51
-13.93%
INO
Inovio Pharmaceuticals
1.23
-0.75
-37.88%
ATOS
Atossa Therapeutics
4.84
-8.22
-62.94%
OVID
Ovid Therapeutics
2.39
2.11
738.60%
SEER
Seer
1.68
-0.40
-19.23%

Biomea Fusion Corporate Events

Business Operations and Strategy
Biomea Fusion Reports Positive Phase 2 T1D Trial Results
Positive
Apr 28, 2026
On April 27, 2026, Biomea Fusion reported positive 52-week results from its Phase 2 COVALENT-112 trial of icovamenib in adults with Stage 3 type 1 diabetes, showing substantial and durable preservation of beta cell function after only 12 weeks of ...
Business Operations and StrategyProduct-Related Announcements
Biomea Fusion Updates Corporate Presentation on Metabolic Pipeline
Positive
Feb 25, 2026
On February 25, 2026, Biomea Fusion updated and published a new corporate presentation for investors and analysts, detailing the status of its metabolic disease pipeline and making the materials available on its website. The refreshed deck undersc...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 14, 2026