Clinical Trial ResultsPositive topline results from the Phase 2 COVALENT-111 clinical trial evaluating icovamenib in patients with T2D were announced.
Safety And TolerabilityIcovamenib was well-tolerated, with no drug discontinuations due to TEAEs, no hypoglycemic events.
Synergistic EffectsPreclinical studies show that icovamenib enhances insulin secretion when combined with GLP-1-based therapies, suggesting a synergistic effect for improved glycemic control.