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AN2 Therapeutics, Inc. (ANTX)
NASDAQ:ANTX
US Market

AN2 Therapeutics, Inc. (ANTX) AI Stock Analysis

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ANTX

AN2 Therapeutics, Inc.

(NASDAQ:ANTX)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$3.00
▲(163.16% Upside)
Action:ReiteratedDate:03/31/26
The score is held back primarily by weak financial performance (no revenue, ongoing losses, and negative free cash flow despite a low-debt balance sheet). Technicals are a relative positive with a bullish longer-term trend and neutral momentum. Valuation remains constrained by losses (negative P/E) and the absence of a dividend.
Positive Factors
Conservatively structured balance sheet (low debt)
AN2's near-absence of debt materially reduces short-term solvency risk and preserves financial flexibility. For a pre-revenue biotech with long development timelines, low leverage lowers bankruptcy risk and gives management more options to fund trials or bridge financing without immediate creditor constraints.
Negative Factors
Pre-commercial profile: no revenue, recurring losses
AN2 remains a development-stage biotech with zero revenue and persistent operating losses. This structural lack of revenue means profitability is unlikely in the near term, requiring continual external funding and leaving margins and free cash flow negative until commercialization or partnerships materialize.
Read all positive and negative factors
Positive Factors
Negative Factors
Conservatively structured balance sheet (low debt)
AN2's near-absence of debt materially reduces short-term solvency risk and preserves financial flexibility. For a pre-revenue biotech with long development timelines, low leverage lowers bankruptcy risk and gives management more options to fund trials or bridge financing without immediate creditor constraints.
Read all positive factors

AN2 Therapeutics, Inc. (ANTX) vs. SPDR S&P 500 ETF (SPY)

AN2 Therapeutics, Inc. Business Overview & Revenue Model

Company Description
AN2 Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing treatments for rare, chronic, and serious infectious diseases. It is developing epetraborole, a once-daily oral treatment for patients with chronic non-tuber...
How the Company Makes Money
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AN2 Therapeutics, Inc. Financial Statement Overview

Summary
Development-stage profile with no revenue and recurring operating/net losses plus sustained negative free cash flow. Offsetting positives include essentially no debt and a moderating cash burn in 2025, but declining equity/assets and deeply negative returns point to ongoing funding/dilution risk.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
27
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit0.000.000.00-77.00K0.00
EBITDA-38.11M3.23M4.90M-40.88M-21.57M
Net Income-35.17M-51.32M-64.73M-40.96M-21.54M
Balance Sheet
Total Assets61.95M92.09M138.74M102.56M65.32M
Cash, Cash Equivalents and Short-Term Investments58.00M83.62M107.30M96.06M58.55M
Total Debt0.000.000.0053.00K0.00
Total Liabilities8.89M10.24M14.04M7.19M3.41M
Stockholders Equity53.06M81.85M124.70M95.37M61.91M
Cash Flow
Free Cash Flow-29.83M-49.26M-53.29M-33.46M-20.48M
Operating Cash Flow-29.83M-49.26M-53.29M-33.46M-20.48M
Investing Cash Flow28.31M54.59M-43.28M-21.77M-50.02M
Financing Cash Flow113.00K372.00K84.99M70.36M78.53M

AN2 Therapeutics, Inc. Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price1.14
Price Trends
50DMA
2.51
Positive
100DMA
1.82
Positive
200DMA
1.49
Positive
Market Momentum
MACD
0.12
Positive
RSI
45.18
Neutral
STOCH
16.85
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ANTX, the sentiment is Neutral. The current price of 1.14 is below the 20-day moving average (MA) of 3.89, below the 50-day MA of 2.51, and below the 200-day MA of 1.49, indicating a neutral trend. The MACD of 0.12 indicates Positive momentum. The RSI at 45.18 is Neutral, neither overbought nor oversold. The STOCH value of 16.85 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for ANTX.

AN2 Therapeutics, Inc. Risk Analysis

AN2 Therapeutics, Inc. disclosed 70 risk factors in its most recent earnings report. AN2 Therapeutics, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

AN2 Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$106.75M-0.98-55.04%44.59%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$74.67M-2.21240.83%-49.17%23.37%
49
Neutral
$49.21M-21.38-311.80%588.40%61.76%
48
Neutral
$32.46M-4.89-695.82%-0.66%-8.43%
47
Neutral
$233.12M-2.32-162.49%5.51%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ANTX
AN2 Therapeutics, Inc.
2.97
1.66
126.72%
DYAI
Dyadic International
0.89
-0.32
-26.45%
CLNN
Clene
6.11
3.03
98.38%
XLO
Xilio Therapeutics
8.51
-1.49
-14.91%
CAMP
CAMP4 Therapeutics Corporation
4.49
2.71
152.25%

AN2 Therapeutics, Inc. Corporate Events

Business Operations and StrategyPrivate Placements and Financing
AN2 Therapeutics Launches New $80 Million ATM Program
Neutral
Apr 9, 2026
On April 9, 2026, AN2 Therapeutics entered into an Open Market Sale Agreement with Jefferies that allows the company to issue and sell up to $80 million of its common stock from time to time via at-the-market offerings on Nasdaq or other existing ...
Business Operations and StrategyExecutive/Board Changes
AN2 Therapeutics Reprices Stock Options to Enhance Retention
Neutral
Mar 20, 2026
On March 19, 2026, AN2 Therapeutics’ board approved a repricing of all outstanding stock options granted under its 2017 and 2022 equity incentive plans, resetting the exercise price of eligible options, including those held by executives and...
Private Placements and Financing
AN2 Therapeutics Announces $40 Million Private Placement Financing
Neutral
Mar 10, 2026
On March 8, 2026, AN2 Therapeutics entered into a securities purchase agreement for a private placement of 8,245,611 common shares and pre-funded warrants for up to 5,789,493 additional shares, priced at about $2.85 each. The transaction, which is...
Business Operations and StrategyExecutive/Board Changes
AN2 Therapeutics adjusts leadership roles and executive compensation
Neutral
Jan 29, 2026
On January 26, 2026, AN2 Therapeutics’ board appointed Sarah Williams, previously the company’s Corporate Controller, as Vice President, Controller and Principal Accounting Officer, effective February 1, 2026, with an increased annual ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 31, 2026