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Century Therapeutics, Inc. (IPSC)
:IPSC
US Market

Century Therapeutics (IPSC) AI Stock Analysis

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Century Therapeutics

(NASDAQ:IPSC)

Rating:45Neutral
Price Target:
$0.50
▼( -13.79% Downside)
Century Therapeutics faces significant financial challenges, with high operational costs and persistent cash flow issues despite revenue growth. Technical analysis reflects short-term momentum but long-term weakness. Valuation metrics are unattractive due to ongoing losses. Recent corporate developments are positive but tempered by a cautious outlook from analysts. Overall, these factors result in a moderately low stock score.
Positive Factors
Clinical Trials
Century Therapeutics is confident it should have a substantial update due to the momentum for CNTY-101 since dosing its first patient.
Technological Advancements
Next-generation Allo-Evasion 5.0 edits could be key to enabling long-term persistence of allogeneic CAR-T cells.
Valuation
Century is adding systemic lupus erythematosus (SLE) to its valuation model to reflect the opportunity in autoimmune indications.
Negative Factors
Clinical Data Interpretation
Several factors, such as diverse autoimmune indications and geographic diversity, could reduce the interpretability of the first CNTY-101 data read-out.
Financial Resources
Century's cash runway is only into the fourth quarter of the following year, which could limit investment in the company's innovative platform.
Market Valuation
The price target for Century Therapeutics was reduced due to a decrease in the peer group valuation component.

Century Therapeutics (IPSC) vs. SPDR S&P 500 ETF (SPY)

Century Therapeutics Business Overview & Revenue Model

Company DescriptionCentury Therapeutics, Inc., a biotechnology company, develops transformative allogeneic cell therapies for the treatment of solid tumor and hematological malignancies. The company's lead product candidate is CNTY-101, an allogeneic, induced pluripotent stem cells (iPSCs)-derived chimeric antigen receptors (CAR)-iNK cell therapy targeting CD19 for relapsed, refractory B-cell lymphoma. It is also developing CNTY-103, a CAR-iNK candidate targeting CD133 + EGFR for recurrent glioblastoma; CNTY-102, a CAR-iT targeting CD19 + CD79b for relapsed, refractory B-cell lymphoma and other B-cell malignancies; CNTY-104, a CAR-iT or CAR-iNK multi-specific candidate for acute myeloid leukemia; and CNTY-106, a CAR-iNK or CAR-iT multi-specific candidate for multiple myeloma. Century Therapeutics, Inc. was founded in 2018 and is headquartered in Philadelphia, Pennsylvania.
How the Company Makes MoneyCentury Therapeutics primarily makes money through the development and commercialization of its cell therapy products. The company generates revenue from collaborations with pharmaceutical companies, where they may receive upfront payments, milestone payments, and royalties based on the successful development and commercialization of joint therapies. Additionally, Century Therapeutics invests in advancing its proprietary pipeline of cell therapy candidates, aiming to bring these products to market and derive revenue from sales. Strategic partnerships, licensing agreements, and potential government grants or funding initiatives may also contribute to its revenue streams.

Century Therapeutics Financial Statement Overview

Summary
Century Therapeutics faces significant financial challenges with persistent losses and negative cash flows. Despite a decent equity buffer, the increasing leverage and inability to generate positive cash flow highlight risks in sustaining operations without external financing.
Income Statement
30
Negative
Century Therapeutics shows a consistent struggle with profitability, indicated by negative gross and net profit margins. The TTM data reveals a worsening EBIT and EBITDA margin, with revenue growth of 20.15%, yet it remains insufficient to cover high operational costs.
Balance Sheet
45
Neutral
While Century Therapeutics maintains a relatively strong equity position, with a debt-to-equity ratio of 0.28, their declining equity ratio from 62.22% in 2022 to 50.34% TTM indicates rising leverage and potential financial strain.
Cash Flow
35
Negative
The company's cash flow situation is challenging, with negative operating and free cash flows, and a negative free cash flow growth rate. The operating cash flow to net income ratio remains below 1, indicating insufficient cash flow generation relative to losses.
Breakdown
TTMDec 2023Dec 2022Dec 2021Dec 2020Dec 2019
Income StatementTotal Revenue
2.69M2.23M5.20M0.000.000.00
Gross Profit
-10.85M-10.81M-4.87M-4.58M-1.75M-249.00K
EBIT
-132.25M-146.55M-133.83M-94.88M-53.90M-245.98M
EBITDA
-117.21M-121.21M-119.34M-89.92M-51.44M-19.78M
Net Income Common Stockholders
-129.89M-136.67M-130.93M-95.82M-54.66M-245.98M
Balance SheetCash, Cash Equivalents and Short-Term Investments
172.74M172.74M315.50M222.88M75.75M81.54M
Total Assets
360.69M360.69M486.54M437.38M106.78M90.90M
Total Debt
48.17M48.17M49.41M23.46M21.55M0.00
Net Debt
847.00K847.00K-34.85M-32.98M-5.66M-44.06M
Total Liabilities
175.94M175.94M183.81M41.14M213.19M182.75M
Stockholders Equity
184.75M184.75M302.74M396.24M-106.41M-91.86M
Cash FlowFree Cash Flow
-113.12M-102.08M-16.55M-133.97M-51.09M-18.63M
Operating Cash Flow
-112.14M-88.35M14.05M-89.00M-41.27M-16.17M
Investing Cash Flow
35.48M61.13M-13.13M-298.34M-22.76M-19.83M
Financing Cash Flow
74.81M-9.72M27.16M417.77M47.69M74.84M

Century Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.58
Price Trends
50DMA
0.52
Positive
100DMA
0.67
Negative
200DMA
1.08
Negative
Market Momentum
MACD
0.01
Negative
RSI
55.58
Neutral
STOCH
67.71
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For IPSC, the sentiment is Positive. The current price of 0.58 is above the 20-day moving average (MA) of 0.54, above the 50-day MA of 0.52, and below the 200-day MA of 1.08, indicating a neutral trend. The MACD of 0.01 indicates Negative momentum. The RSI at 55.58 is Neutral, neither overbought nor oversold. The STOCH value of 67.71 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for IPSC.

Century Therapeutics Risk Analysis

Century Therapeutics disclosed 90 risk factors in its most recent earnings report. Century Therapeutics reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 3 New Risks
1.
Repurchase of Shares of Company Equity Securities Q3, 2024
2.
Item 2. Unregistered Sales of Equity Securities, Use of Proceeds, and Issuer Purchases of Equity Securities Recent Sales of Unregistered Securities Q3, 2024
3.
Item 3. Defaults Upon Senior Securities. Q3, 2024

Century Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (53)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
53
Neutral
$5.14B3.06-43.57%2.81%16.81%-0.12%
46
Neutral
$41.16M-59.49%21.15%46.44%
46
Neutral
$49.34M-71.90%69.65%27.98%
45
Neutral
$49.47M-10.49%8286.79%87.23%
45
Neutral
$55.80M-232.51%138.11%76.60%
44
Neutral
$19.53M-83.73%42.39%
35
Underperform
$75.71M-101.34%21.40%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IPSC
Century Therapeutics
0.57
-2.55
-81.73%
PASG
Passage Bio
0.35
-0.87
-71.31%
CELU
Celularity
2.49
-0.98
-28.24%
JSPR
Jasper Therapeutics
4.87
-18.95
-79.55%
KRON
Kronos Bio
0.69
-0.28
-28.87%
STTK
Shattuck Labs
1.00
-6.49
-86.65%

Century Therapeutics Corporate Events

Business Operations and StrategyFinancial Disclosures
Century Therapeutics Reports Strong Q1 2025 Financial Results
Positive
May 15, 2025

On May 15, 2025, Century Therapeutics reported its first-quarter financial results and provided a business update. The company initiated patient dosing in the Phase 1 CALiPSO-1 trial for CNTY-101 in the U.S., with plans to expand to Europe. Century is also preparing to start IND-enabling studies for CNTY-308 in mid-2025. Financially, the company reported a net income of $76.6 million for the quarter, significantly up from a net loss in the same period last year, largely due to collaboration revenue from a terminated agreement with Bristol-Myers Squibb.

The most recent analyst rating on (IPSC) stock is a Buy with a $4.00 price target. To see the full list of analyst forecasts on Century Therapeutics stock, see the IPSC Stock Forecast page.

Product-Related AnnouncementsBusiness Operations and Strategy
Century Therapeutics Re-prioritizes Pipeline for Key Programs
Neutral
Mar 19, 2025

Century Therapeutics announced a strategic re-prioritization of its pipeline to focus on four transformative programs, particularly CNTY-308 and CNTY-101, aimed at B-cell mediated autoimmune diseases and malignancies. The company reported a strong cash position, extending its runway into the fourth quarter of 2026, and highlighted its decision to discontinue the ELiPSE-1 trial due to unmet transformational thresholds in late-stage R/R NHL, while emphasizing the potential of CNTY-101 in autoimmune diseases.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.