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Shattuck Labs, Inc. (STTK)
NASDAQ:STTK
US Market
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Shattuck Labs (STTK) AI Stock Analysis

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STTK

Shattuck Labs

(NASDAQ:STTK)

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Neutral 53 (OpenAI - 5.2)
Rating:53Neutral
Price Target:
$8.00
▲(6.24% Upside)
Action:ReiteratedDate:04/21/26
The score is held back primarily by weak financial performance (minimal/volatile revenue, large losses, and ongoing cash burn). Technicals are supportive with a strong uptrend, but overbought signals add near-term risk. Valuation is constrained by negative earnings, while the ATM offering modestly helps funding flexibility but carries dilution risk.
Positive Factors
Proprietary ARC platform & pipeline
Shattuck’s ARC platform creates a durable technical moat by enabling engineered, multi-functional biologics targeting immune checkpoints. As a platform with clinical and preclinical assets, it supports multiple development shots on goal and long-term value creation if trials advance.
Negative Factors
Significant cash burn
Material negative operating and free cash flow indicate persistent cash burn that must be covered by external financing. Ongoing negative cash generation elevates dilution risk, forces management to prioritize fundraising over operations, and creates execution risk if capital access tightens.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary ARC platform & pipeline
Shattuck’s ARC platform creates a durable technical moat by enabling engineered, multi-functional biologics targeting immune checkpoints. As a platform with clinical and preclinical assets, it supports multiple development shots on goal and long-term value creation if trials advance.
Read all positive factors

Shattuck Labs (STTK) vs. SPDR S&P 500 ETF (SPY)

Shattuck Labs Business Overview & Revenue Model

Company Description
Shattuck Labs, Inc., a clinical-stage biotechnology company, develops therapeutics for the treatment of cancer and autoimmune disease in the United States. The company's lead product candidate is SL-172154, which is in Phase 1 clinical trial for t...
How the Company Makes Money
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Shattuck Labs Financial Statement Overview

Summary
Overall financial profile is weak despite a clean leverage position: revenue is highly volatile and currently minimal, profitability is deeply negative with large operating losses, and cash burn remains significant (negative operating and free cash flow). The main offset is low debt, which reduces near-term balance-sheet risk.
Income Statement
14
Very Negative
Balance Sheet
74
Positive
Cash Flow
22
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue1.00M5.72M1.66M652.00K30.02M
Gross Profit-2.69M5.72M-2.38M652.00K28.64M
EBITDA-47.84M-76.74M-87.92M-100.26M-43.89M
Net Income-48.81M-75.41M-87.30M-101.94M-44.97M
Balance Sheet
Total Assets91.03M91.05M159.56M205.32M298.58M
Cash, Cash Equivalents and Short-Term Investments78.06M72.99M130.63M161.28M268.80M
Total Debt1.58M3.41M4.20M4.90M0.00
Total Liabilities8.64M11.42M14.86M29.17M26.80M
Stockholders Equity82.39M79.63M144.71M176.16M271.79M
Cash Flow
Free Cash Flow-39.95M-60.57M-81.64M-106.11M-65.04M
Operating Cash Flow-39.88M-60.52M-81.23M-94.50M-57.12M
Investing Cash Flow-7.89M-8.51M110.86M49.44M-10.44M
Financing Cash Flow44.57M787.00K48.62M171.00K1.93M

Shattuck Labs Technical Analysis

Technical Analysis Sentiment
Positive
Last Price7.53
Price Trends
50DMA
5.49
Positive
100DMA
4.51
Positive
200DMA
3.01
Positive
Market Momentum
MACD
0.49
Negative
RSI
71.00
Negative
STOCH
77.23
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For STTK, the sentiment is Positive. The current price of 7.53 is above the 20-day moving average (MA) of 6.64, above the 50-day MA of 5.49, and above the 200-day MA of 3.01, indicating a bullish trend. The MACD of 0.49 indicates Negative momentum. The RSI at 71.00 is Negative, neither overbought nor oversold. The STOCH value of 77.23 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for STTK.

Shattuck Labs Risk Analysis

Shattuck Labs disclosed 55 risk factors in its most recent earnings report. Shattuck Labs reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Shattuck Labs Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$88.16M-2.64-291.42%54.52%
53
Neutral
$585.00M-7.52-65.03%-82.52%47.92%
53
Neutral
$74.00M-1.19-57.23%16.95%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$48.05M-21.38-311.80%589.88%69.82%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
STTK
Shattuck Labs
7.72
6.92
865.00%
PYPD
PolyPid
4.58
2.06
81.75%
COEP
Coeptis Therapeutics Holdings
15.20
6.23
69.45%
XLO
Xilio Therapeutics
8.18
-2.81
-25.58%
ACRV
Acrivon Therapeutics, Inc.
1.88
0.33
21.29%

Shattuck Labs Corporate Events

Regulatory Filings and ComplianceShareholder Meetings
Shattuck Labs Sets Earlier Date for 2026 Annual Meeting
Neutral
Feb 5, 2026
On February 5, 2026, Shattuck Labs’ board set May 28, 2026 as the date for its 2026 annual meeting of stockholders, a shift to a significantly earlier meeting date than the prior year. As a result of this scheduling change, the company revis...
Business Operations and StrategyPrivate Placements and Financing
Shattuck Labs Launches $75 Million At-The-Market Offering
Positive
Jan 22, 2026
On January 22, 2026, Shattuck Labs, Inc. entered into a sales agreement with Leerink Partners LLC to offer and sell from time to time up to $75 million of its common stock through an at-the-market equity program registered under an effective shelf...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 21, 2026