Clinical MilestoneAnalyst highlights an upcoming Phase I readout scheduled for the second quarter of 2026 on safety, receptor occupancy, immunogenicity and pharmacokinetics as a potential de‑risking event that could reshape program valuation.
Immunogenicity ProfileAnalyst expects SL-325's cell-bound design to lower the likelihood of anti‑drug antibody formation, which may preserve treatment effect and enable combination therapy strategies.
Mechanism DifferentiationAnalyst notes SL-325's targeting of the DR3 receptor could provide stronger and more durable reduction of intestinal inflammation compared with TL1A blockade, offering a clear mechanism-based differentiation in inflammatory disease treatment.