H.C. Wainwright analyst Joseph Pantginis has maintained their neutral stance on STTK stock, giving a Hold rating on August 14.
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Joseph Pantginis has given his Hold rating due to a combination of factors related to Shattuck Labs’ current clinical developments and strategic positioning. The company recently received FDA clearance for its investigational new drug application for SL-325, a novel DR3 antagonist antibody aimed at treating inflammatory bowel disease. This advancement marks a significant step forward, as the Phase 1 clinical trial is set to evaluate the safety and efficacy of SL-325 in healthy volunteers, with dosing expected to begin in the third quarter of 2025.
Despite the promising preclinical data presented at the ECCO Congress, which highlighted the potential of SL-325 to offer a differentiated approach in targeting the TL1A/DR3 signaling pathway, Pantginis maintains a cautious stance. The Hold rating reflects the early stage of clinical development and the inherent uncertainties associated with the transition from preclinical to clinical phases. Additionally, while the preclinical results are encouraging, further validation in human studies is necessary to substantiate the therapeutic potential and safety profile of SL-325, warranting a neutral outlook at this juncture.