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Kalaris Therapeutics (KLRS)
NASDAQ:KLRS
US Market
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Kalaris Therapeutics (KLRS) AI Stock Analysis

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KLRS

Kalaris Therapeutics

(NASDAQ:KLRS)

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Neutral 46 (OpenAI - 5.2)
Rating:46Neutral
Price Target:
$4.50
▼(-28.80% Downside)
Action:Reiterated
Date:06/05/26
The score is primarily held back by development-stage fundamentals (no revenue, large losses, and ongoing cash burn) and bearish technicals (below major moving averages with negative MACD). Corporate updates and runway/governance stability provide some support, but do not outweigh the current profitability and trend risks.
Positive Factors
Cash runway / financing
A funded runway into Q4 2027 and an oversubscribed $50M placement provide multi-year capital to advance TH103 toward Phase 3. This reduces near-term refinancing risk, enabling execution on clinical milestones that materially de-risk value creation over the next 2–3 years.
Negative Factors
Pre-revenue cash burn
Zero product revenue combined with sustained operating cash burn requires ongoing external financing to fund R&D. Persistent large negative cash flow increases dilution risk and creates execution pressure if capital markets tighten, challenging long-term program advancement.
Read all positive and negative factors
Positive Factors
Negative Factors
Cash runway / financing
A funded runway into Q4 2027 and an oversubscribed $50M placement provide multi-year capital to advance TH103 toward Phase 3. This reduces near-term refinancing risk, enabling execution on clinical milestones that materially de-risk value creation over the next 2–3 years.
Read all positive factors

Kalaris Therapeutics (KLRS) vs. SPDR S&P 500 ETF (SPY)

Kalaris Therapeutics Business Overview & Revenue Model

Company Description
Kalaris Therapeutics Inc. operates as a pharmaceutical enterprise. The company's core mission centers on developing innovative cell therapies. These treatments are designed to reactivate the body's inherent immunity against critical, virus-linked ...
How the Company Makes Money
As a clinical-stage biotechnology company, Kalaris Therapeutics has historically not depended on recurring product sales; its cash inflows are typically driven by financing activities rather than commercial revenue. Common sources include proceeds...

Kalaris Therapeutics Financial Statement Overview

Summary
Income statement and cash flow are weak due to zero revenue and large ongoing losses with significant operating/free-cash-flow burn, despite some improvement versus 2024. The balance sheet is a partial offset with low debt relative to equity, but equity has eroded over time and returns remain strongly negative.
Income Statement
14
Very Negative
Balance Sheet
58
Neutral
Cash Flow
22
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-20.00K-13.00K0.000.000.00-1.12M
EBITDA-44.09M-41.98M-58.77M-14.01M-15.25M-169.84M
Net Income-44.10M-43.44M-58.77M-14.70M-15.48M-171.96M
Balance Sheet
Total Assets109.81M121.74M118.55M3.33M3.90M286.59M
Cash, Cash Equivalents and Short-Term Investments97.22M117.98M118.29M3.17M3.06M248.12M
Total Debt1.41M1.45M0.000.003.25M30.07M
Total Liabilities41.25M42.92M5.24M48.35M34.17M61.33M
Stockholders Equity68.56M78.81M113.31M-45.02M-30.27M225.27M
Cash Flow
Free Cash Flow-49.09M-43.18M-67.70M-14.13M-9.78M-106.34M
Operating Cash Flow-48.88M-42.98M-67.70M-14.13M-9.78M-106.32M
Investing Cash Flow-70.07M-19.72M95.00M0.000.00185.98M
Financing Cash Flow52.42M159.61M21.00K14.24M12.78M232.00K

Kalaris Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price6.32
Price Trends
50DMA
5.36
Negative
100DMA
7.08
Negative
200DMA
6.67
Negative
Market Momentum
MACD
-0.33
Positive
RSI
37.52
Neutral
STOCH
23.58
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For KLRS, the sentiment is Negative. The current price of 6.32 is above the 20-day moving average (MA) of 4.73, above the 50-day MA of 5.36, and below the 200-day MA of 6.67, indicating a bearish trend. The MACD of -0.33 indicates Positive momentum. The RSI at 37.52 is Neutral, neither overbought nor oversold. The STOCH value of 23.58 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for KLRS.

Kalaris Therapeutics Risk Analysis

Kalaris Therapeutics disclosed 75 risk factors in its most recent earnings report. Kalaris Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Kalaris Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$2.01B-9.29-87.00%-36.24%11.52%
48
Neutral
$215.95M-1.26-174.71%-76.26%-9.93%
48
Neutral
$2.13B-9.13-253.85%-15.28%
46
Neutral
$94.51M-2.33-72.78%73.91%
46
Neutral
$231.85M-4.79-80.61%43.21%-15.55%
46
Neutral
$55.20M-1.16-127.30%49.74%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
KLRS
Kalaris Therapeutics
4.33
1.66
62.17%
CHRS
Coherus Biosciences
1.40
0.61
78.34%
NKTR
Nektar Therapeutics
59.38
50.13
541.95%
CLLS
Cellectis SA
3.09
1.71
123.91%
MCRB
Seres Therapeutics
5.70
-1.80
-24.00%
KOD
Kodiak Sciences
34.06
30.32
810.70%

Kalaris Therapeutics Corporate Events

Executive/Board ChangesShareholder Meetings
Kalaris Therapeutics Shareholders Back Board, Pay and Auditor
Positive
Jun 4, 2026
At its 2026 Annual Meeting of Stockholders held on June 3, 2026, Kalaris Therapeutics, Inc. stockholders elected Napoleone Ferrara, M.D., David Hallal and Leone Patterson as Class III directors to serve three-year terms expiring at the 2029 annual...
Executive/Board Changes
Kalaris Therapeutics Announces CFO Resignation, Finance Leadership Shift
Neutral
Apr 10, 2026
On April 8, 2026, Kalaris Therapeutics, Inc. disclosed that Chief Financial Officer Matthew Gall had decided to resign from his position, with his departure to take effect on April 14, 2026. The move triggers a leadership transition in the finance...
Business Operations and StrategyPrivate Placements and Financing
Kalaris Updates TH103 Strategy and Highlights Cash Runway
Positive
Mar 9, 2026
On March 9, 2026, Kalaris Therapeutics released an updated corporate presentation for use at the Leerink Partners Global Healthcare Conference and other investor meetings, outlining revised timelines for data readouts from its Phase 1b/2 multi-asc...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 05, 2026