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Coherus Biosciences (CHRS)
NASDAQ:CHRS
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Coherus Biosciences (CHRS) AI Stock Analysis

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CHRS

Coherus Biosciences

(NASDAQ:CHRS)

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Neutral 46 (OpenAI - 4o)
Rating:46Neutral
Price Target:
$1.50
▲(11.94% Upside)
The overall stock score is primarily impacted by significant financial challenges, including declining revenue and profitability, high leverage, and cash flow issues. Technical analysis also indicates bearish momentum. However, the earnings call provides some optimism with strategic initiatives and pipeline progress, slightly offsetting the negative financial performance.
Positive Factors
Pipeline Progress
The advancement of clinical trials and the pursuit of multiple cancer indications demonstrate Coherus' scientific leadership and potential for future revenue growth.
Market Expansion
Expanding the sales force and implementing a remote team will enhance market penetration, potentially increasing sales and market share in the long term.
Balance Sheet Improvement
Improved debt-to-equity ratio enhances financial stability and flexibility, allowing Coherus to invest in growth opportunities without excessive financial risk.
Negative Factors
Declining Revenue
Declining revenue and profitability indicate operational challenges and may hinder the company's ability to invest in growth and innovation.
Cash Flow Challenges
Negative cash flows can limit Coherus' ability to fund operations and strategic initiatives, potentially impacting long-term growth and stability.
Community Engagement Issues
Low awareness among community physicians can limit market penetration and sales growth, affecting the company's ability to expand its customer base.

Coherus Biosciences (CHRS) vs. SPDR S&P 500 ETF (SPY)

Coherus Biosciences Business Overview & Revenue Model

Company DescriptionCoherus Biosciences (CHRS) is a biotechnology company focused on developing and commercializing innovative biologic medicines. The company specializes in biosimilars, which are biologic medical products highly similar to already approved reference products, aimed at improving patient access to essential therapies. Coherus operates primarily in the oncology and autoimmune disease sectors, offering a range of products that include both FDA-approved biosimilars and a robust pipeline of candidates in various stages of development.
How the Company Makes MoneyCoherus Biosciences generates revenue primarily through the sale of its biosimilar products. The company has established key partnerships with other pharmaceutical companies to enhance its research and development capabilities and expand its market reach. Significant revenue streams include product sales from its approved biosimilars, royalties from collaborations, and potential milestone payments associated with its pipeline products. Additionally, the company may benefit from expanding its portfolio of biosimilars as it seeks to capture market share in the growing biosimilars market, which is driven by increasing demand for cost-effective biologic therapies.

Coherus Biosciences Earnings Call Summary

Earnings Call Date:Nov 06, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 17, 2026
Earnings Call Sentiment Positive
The earnings call reflects a generally positive outlook, with strong financial performance, strategic focus on pipeline development, and effective market expansion strategies. However, some challenges remain in regional sales discrepancies and community physician engagement.
Q3-2025 Updates
Positive Updates
Strong Financial Performance
LOQTORZI net revenue grew to $11.2 million, a 12% increase quarter-over-quarter and 92% increase year-over-year. The company has significantly improved its balance sheet with $192 million in cash and investments and a 69% decrease in non-TSA liabilities.
Pipeline Progress and Strategic Focus
Coherus Oncology is advancing its clinical trials, particularly with LOQTORZI in combination with proprietary assets like CHS-114 and casdozokitug. Enrollment is on track, and the company is pursuing multiple cancer indications, demonstrating its scientific leadership.
Market Expansion and Sales Strategy
The company is expanding its sales force by 15% and implementing a remote sales team to increase reach, particularly in the community setting where awareness of LOQTORZI's clinical benefits needs reinforcement.
Reduction in Operating Expenses
SG&A expenses decreased by 11% compared to last year due to decreased headcount, reflecting the company's focus on spending discipline and operational streamlining.
Negative Updates
Regional Sales Discrepancies
One region showed flat demand for LOQTORZI due to post-restructure vacancies, impacting the overall national average growth despite other regions performing well.
Challenges in Community Physician Engagement
There is low awareness of LOQTORZI's preferred position in NCCN guidelines among community physicians, which affects its market penetration outside of hospital-based specialists.
Company Guidance
In the Coherus Oncology Q3 2025 Earnings Conference Call, the company provided guidance reflecting strong execution across financial, operational, and strategic dimensions. They reported a significant 12% quarter-over-quarter increase in LOQTORZI sales, reaching $11.2 million, with expectations to achieve $150-$200 million in peak sales by mid-2028. Coherus has streamlined operations, reducing SG&A expenses by 11% year-over-year, and forecasting annual SG&A costs of $90-$100 million for 2025. They have bolstered their balance sheet, maintaining $192 million in cash and investments, and paying down near-term debt. The company is advancing its clinical programs with CHS-114 and casdozokitug, aiming for multiple data readouts in 2026, while exploring global partnering opportunities to support development costs. Coherus also announced strategic initiatives to expand its commercial reach, including sales force expansion and enhanced multichannel educational efforts to drive growth in the community segment.

Coherus Biosciences Financial Statement Overview

Summary
Coherus Biosciences is facing substantial financial challenges across all verticals. The income statement shows declining revenue and profitability, the balance sheet indicates high leverage and negative equity returns, and cash flow statements reveal significant cash management issues. The company needs to address these operational and financial inefficiencies to stabilize its financial health.
Income Statement
35
Negative
The income statement shows a concerning trend with declining revenue and profitability. The TTM data indicates a significant revenue drop of 27.7%, and the net profit margin is highly volatile, showing a large positive due to non-operational factors. Gross profit margin remains relatively stable, but EBIT and EBITDA margins are negative, indicating operational challenges.
Balance Sheet
40
Negative
The balance sheet reflects a mixed picture. The debt-to-equity ratio has improved significantly in the TTM period, indicating reduced leverage. However, the return on equity is negative, suggesting inefficiencies in generating returns from equity. The equity ratio is not favorable, indicating potential financial instability.
Cash Flow
30
Negative
Cash flow analysis reveals significant challenges. The TTM period shows negative operating and free cash flows, with a dramatic decline in free cash flow growth. The operating cash flow to net income ratio is negative, indicating cash flow issues relative to reported earnings.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue83.57M266.96M257.24M211.04M326.55M475.82M
Gross Profit32.09M149.41M98.25M140.96M268.96M438.16M
EBITDA-174.42M60.94M-193.94M-255.58M-260.69M161.84M
Net Income154.97M28.51M-237.89M-291.75M-287.10M132.24M
Balance Sheet
Total Assets516.52M448.53M629.60M480.85M679.33M841.65M
Cash, Cash Equivalents and Short-Term Investments191.66M125.99M117.75M191.68M417.19M541.16M
Total Debt1.95M269.90M480.84M480.42M419.02M417.10M
Total Liabilities428.75M580.52M823.03M618.26M581.61M560.67M
Stockholders Equity87.77M-131.99M-193.43M-137.42M97.73M280.97M
Cash Flow
Free Cash Flow-90.19M-20.44M-175.17M-243.16M-38.72M147.09M
Operating Cash Flow-90.19M-20.44M-174.88M-241.12M-37.43M154.15M
Investing Cash Flow377.38M230.32M144.64M-166.85M-138.41M-14.40M
Financing Cash Flow-281.56M-186.97M69.60M54.33M51.88M223.95M

Coherus Biosciences Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.34
Price Trends
50DMA
1.55
Negative
100DMA
1.24
Positive
200DMA
1.10
Positive
Market Momentum
MACD
-0.02
Positive
RSI
33.61
Neutral
STOCH
24.92
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CHRS, the sentiment is Negative. The current price of 1.34 is below the 20-day moving average (MA) of 1.65, below the 50-day MA of 1.55, and above the 200-day MA of 1.10, indicating a neutral trend. The MACD of -0.02 indicates Positive momentum. The RSI at 33.61 is Neutral, neither overbought nor oversold. The STOCH value of 24.92 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CHRS.

Coherus Biosciences Risk Analysis

Coherus Biosciences disclosed 68 risk factors in its most recent earnings report. Coherus Biosciences reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Coherus Biosciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
69
Neutral
$174.61M29.5915.99%62.79%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$206.09M-4.79-51.06%-44.94%-274.42%
46
Neutral
$161.97M-860.65%-72.54%-19972.15%
46
Neutral
$162.51M-271.32%-75.77%-31.24%
43
Neutral
$198.87M-180.71%64.43%
42
Neutral
$125.38M23.0915.95%448.44%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CHRS
Coherus Biosciences
1.34
0.56
71.79%
SLS
SELLAS Life Sciences Group
1.59
0.34
27.20%
PLX
Protalix
2.19
0.99
82.50%
MCRB
Seres Therapeutics
14.02
0.19
1.37%
GNFT
Genfit SA
3.89
-1.34
-25.62%
IPHA
Innate Pharma
1.78
-0.07
-3.78%

Coherus Biosciences Corporate Events

Coherus Oncology Reports Q3 2025 Financial Results
Nov 7, 2025

Coherus Oncology, Inc. is a commercial-stage biotechnology company specializing in innovative oncology therapies, with a focus on developing and commercializing treatments for various types of cancer. The company is known for its next-generation PD-1 inhibitor, LOQTORZI, and a robust pipeline of clinical candidates targeting multiple cancer indications.

Delistings and Listing ChangesRegulatory Filings and Compliance
Coherus Biosciences Regains Nasdaq Compliance
Positive
Sep 8, 2025

On June 30, 2025, Coherus Oncology, Inc. received a deficiency notice from Nasdaq due to its stock price falling below $1.00 per share for 30 consecutive business days. By September 5, 2025, the company regained compliance with Nasdaq’s listing requirements, ensuring its continued presence on the Nasdaq Global Market.

The most recent analyst rating on (CHRS) stock is a Buy with a $4.00 price target. To see the full list of analyst forecasts on Coherus Biosciences stock, see the CHRS Stock Forecast page.

Coherus Oncology’s Earnings Call Highlights Growth and Challenges
Aug 12, 2025

Coherus Oncology’s recent earnings call projected an optimistic outlook, underscored by robust revenue growth and successful strategic repositioning. Despite these positive developments, the company acknowledged challenges in community adoption and a reliance on future data readouts for continued success.

Coherus Oncology Reports Strong Q2 2025 Growth
Aug 8, 2025

Coherus Oncology is a commercial-stage oncology company focused on developing innovative cancer treatments, with a proprietary pipeline that includes LOQTORZI, a PD-1 inhibitor, and other promising candidates targeting various solid tumors. In its second-quarter 2025 earnings report, Coherus Oncology announced a significant 36% increase in net revenue for LOQTORZI, reaching $10 million, driven by increased patient demand and inventory restocking. The company also highlighted its strong cash position of $238 million, providing a runway through 2026 to support its ongoing clinical programs. Key financial metrics included a net loss from continuing operations of $44.9 million, an improvement from the previous year’s loss, and a substantial net income from discontinued operations due to the UDENYCA divestiture. Coherus is advancing its clinical pipeline with CHS-114 and casdozokitug, with data readouts expected in 2026, and aims to expand LOQTORZI’s market potential through strategic partnerships and label expansions. Looking ahead, Coherus remains focused on maximizing LOQTORZI’s potential and advancing its pipeline, with management optimistic about unlocking significant market opportunities and enhancing patient outcomes.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 08, 2025