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Coherus Biosciences (CHRS)
NASDAQ:CHRS
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Coherus Biosciences (CHRS) AI Stock Analysis

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CHRS

Coherus Biosciences

(NASDAQ:CHRS)

Rating:48Neutral
Price Target:
$1.00
▼(-1.96% Downside)
Coherus Biosciences faces significant financial challenges, with declining revenue and cash flow issues being the most critical factors. While there is some positive momentum from the earnings call and strategic rebranding, the risk of delisting and poor valuation metrics weigh heavily on the stock's outlook.
Positive Factors
Market Position
Loqtorzi has restored growth momentum and targets the community setting to drive further expansion, supported by strong uptake following its inclusion in NCCN guidelines.
Product Development
Development of anti-CCR8 mAb CHS-114 and IL-27 antagonist casdozokitug progresses apace, with Coherus owning global rights and seeking ex-US partners.
Strategic Shift
Coherus completed its strategic transition to focus on novel oncology, marked by the sale of its biosimilar business, which extinguished debt and provided funding for future growth.
Negative Factors
Financial Performance
Non-GAAP net loss was worse than forecast, with Q2 showing a loss of $0.34 per share, $0.01 worse than anticipated.
Market Competition
Checkpoint inhibitors remain a crowded space dominated by large pharma players, and Coherus' pipeline assets are relatively early stage.
Sales Performance
Loqtorzi sales of $7.6MM in Q1 were slightly below estimates, reflecting little quarter-on-quarter growth.

Coherus Biosciences (CHRS) vs. SPDR S&P 500 ETF (SPY)

Coherus Biosciences Business Overview & Revenue Model

Company DescriptionCoherus BioSciences, Inc., a biopharmaceutical company, focuses on the biosimilar and immuno-oncology market primarily in the United States. The company markets UDENYCA, a biosimilar to Neulasta, a long-acting granulocyte stimulating colony factor in the United States. Its pipeline products include biosimilars of Humira, Avastin, and Lucentis. The company also develops Toripalimab, a novel anti-PD-1 antibody for second-line treatment of melanoma in China; Bevacizumab biosimilar; and CHS-1420, an anti-TNF product candidate, as an adalimumab biosimilar; Ranibizumab biosimilar. Coherus BioSciences, Inc. has license agreements with Selexis SA; AbbVie, Inc.; Pfizer, Inc.; Bioeq AG; Innovent Biologics (Suzhou) Co., Ltd.; and Junshi Biosciences. The company was formerly known as BioGenerics, Inc. and changed its name to Coherus BioSciences, Inc. in April 2012. Coherus BioSciences, Inc. was incorporated in 2010 and is headquartered in Redwood City, California.
How the Company Makes MoneyCoherus Biosciences generates revenue primarily through the sale of its biosimilar products. The company has established key partnerships with other pharmaceutical companies to enhance its research and development capabilities and expand its market reach. Significant revenue streams include product sales from its approved biosimilars, royalties from collaborations, and potential milestone payments associated with its pipeline products. Additionally, the company may benefit from expanding its portfolio of biosimilars as it seeks to capture market share in the growing biosimilars market, which is driven by increasing demand for cost-effective biologic therapies.

Coherus Biosciences Earnings Call Summary

Earnings Call Date:Aug 07, 2025
(Q2-2025)
|
% Change Since: 15.91%|
Next Earnings Date:Nov 10, 2025
Earnings Call Sentiment Positive
The earnings call conveyed a mostly positive outlook for Coherus Oncology, emphasizing strong revenue growth and strategic repositioning success. However, challenges with community adoption and dependency on future data readouts were noted.
Q2-2025 Updates
Positive Updates
Record Growth for LOQTORZI
LOQTORZI's net revenue in Q2 2025 grew 36% over Q1 2025 to $10 million, marking a 65% increase year-over-year. This growth was driven by strong demand and increased adoption by physicians.
Strategic Repositioning Completed
The company has been renamed to Coherus Oncology to focus on innovative oncology, completing a strategic repositioning.
Strong Financial Position
Ended Q2 with $238 million in cash and investments, providing a runway through 2026.
Cost Management Success
Achieved $30 million in annualized savings from headcount reductions, exceeding the $25 million target. SG&A costs are projected between $90 million and $100 million for 2025.
Negative Updates
Challenges in Community Adoption
While LOQTORZI adoption is strong in academic settings, community adoption remains slower due to dispersed patient volume and lack of immediate awareness among community oncologists.
Dependency on Future Data Readouts
Many development strategies and partnerships for pipeline assets like CHS-114 and casdozokitug are contingent on positive data readouts expected in 2026.
Company Guidance
During the Coherus Oncology earnings call for Q2 2025, the company provided guidance on several key metrics reflecting its strategic progress and financial health. Coherus reported net revenue of $10 million for LOQTORZI, marking a 36% increase over Q1 2025 and a 65% increase year-over-year. The company aims to reach a revenue target of $40 million to $50 million for 2025, driven by growing adoption in the nasopharyngeal cancer market, estimated at $150 million to $200 million. Coherus also highlighted the potential of its pipeline assets, CHS-114 and casdozokitug, with promising clinical data expected by the first half of 2026. Financially, Coherus ended Q2 with $238 million in cash and investments, projecting sufficient funds to support operations through 2026. The company achieved approximately $30 million in annualized savings from headcount reductions and expects further savings as it continues to streamline operations.

Coherus Biosciences Financial Statement Overview

Summary
Coherus Biosciences faces substantial financial challenges with declining revenues, persistent losses, and high leverage. The negative equity position and reliance on financing highlight potential risks. Improvement in operational performance and financial stability is critical for future growth.
Income Statement
45
Neutral
The income statement reveals significant challenges for Coherus Biosciences, with declining revenue and consistent net losses over the periods. The TTM data shows negative margins across gross profit, EBIT, and EBITDA, indicating profitability issues. Revenue growth is negative, reflecting a downward trend in sales.
Balance Sheet
30
Negative
The balance sheet indicates high financial leverage with a negative stockholders' equity, suggesting insolvency risks. The debt-to-equity ratio is not calculable due to negative equity, and the equity ratio is negative, underscoring financial instability. Overall, the balance sheet reflects potential risks due to high liabilities.
Cash Flow
40
Negative
Cash flow analysis shows limited operational cash generation with a marginally positive free cash flow in the TTM period. However, historical data reflects negative operating and free cash flows, indicating reliance on external financing. The operating cash flow to net income ratio is unfavorable, suggesting inefficiencies in cash conversion.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue142.77M266.96M257.24M211.04M326.55M475.82M
Gross Profit81.11M149.41M98.25M140.96M268.96M438.16M
EBITDA-137.84M60.94M-193.94M-255.58M-260.69M161.84M
Net Income179.75M28.51M-237.89M-291.75M-287.10M132.24M
Balance Sheet
Total Assets439.46M448.53M629.60M480.85M679.33M841.65M
Cash, Cash Equivalents and Short-Term Investments237.64M125.99M117.75M191.68M417.19M541.16M
Total Debt2.41M269.90M480.84M480.42M419.02M417.10M
Total Liabilities319.64M580.52M823.03M618.26M581.61M560.67M
Stockholders Equity119.83M-131.99M-193.43M-137.42M97.73M280.97M
Cash Flow
Free Cash Flow-105.87M-20.44M-175.17M-243.16M-38.72M147.09M
Operating Cash Flow-105.87M-20.44M-174.88M-241.12M-37.43M154.15M
Investing Cash Flow445.05M230.32M144.64M-166.85M-138.41M-14.40M
Financing Cash Flow-281.72M-186.97M69.60M54.33M51.88M223.95M

Coherus Biosciences Technical Analysis

Technical Analysis Sentiment
Positive
Last Price1.02
Price Trends
50DMA
0.86
Positive
100DMA
0.88
Positive
200DMA
1.03
Negative
Market Momentum
MACD
0.02
Negative
RSI
60.59
Neutral
STOCH
81.23
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CHRS, the sentiment is Positive. The current price of 1.02 is above the 20-day moving average (MA) of 0.94, above the 50-day MA of 0.86, and below the 200-day MA of 1.03, indicating a neutral trend. The MACD of 0.02 indicates Negative momentum. The RSI at 60.59 is Neutral, neither overbought nor oversold. The STOCH value of 81.23 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CHRS.

Coherus Biosciences Risk Analysis

Coherus Biosciences disclosed 68 risk factors in its most recent earnings report. Coherus Biosciences reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Coherus Biosciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (65)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
65
Neutral
¥341.84B11.04-0.17%2.40%9.73%-9.93%
48
Neutral
$106.45M5.55-860.65%-53.67%-330.15%
43
Neutral
$163.21M-180.71%64.43%
$98.78M-15.23%
54
Neutral
$120.50M-98.72%-100.00%11.41%
41
Neutral
$90.04M-31.55%6.27%
34
Underperform
$190.67M-51.74%29.72%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CHRS
Coherus Biosciences
1.02
-0.53
-34.19%
SLS
SELLAS Life Sciences Group
1.55
0.28
22.05%
XBIT
XBiotech
3.24
-3.13
-49.14%
NAUT
Nautilus Biotechnolgy
0.72
-1.59
-68.83%
TIL
Instil Bio
28.24
18.02
176.32%
GNLX
Genelux Corp.
3.41
1.28
60.09%

Coherus Biosciences Corporate Events

Delistings and Listing ChangesRegulatory Filings and Compliance
Coherus Biosciences Receives Nasdaq Deficiency Notice
Negative
Jul 3, 2025

On June 30, 2025, Coherus Oncology, Inc. received a deficiency notice from Nasdaq due to its stock price falling below $1.00 for 30 consecutive business days, which is below the required minimum for continued listing. The company has until December 29, 2025, to regain compliance by maintaining a minimum closing bid price of $1.00 per share for 10 consecutive business days. If Coherus fails to meet this requirement, it may seek an additional compliance period or face potential delisting, with options to appeal any delisting determination.

The most recent analyst rating on (CHRS) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on Coherus Biosciences stock, see the CHRS Stock Forecast page.

Executive/Board ChangesShareholder Meetings
Coherus Biosciences Holds Virtual Annual Stockholder Meeting
Neutral
Jun 13, 2025

On June 11, 2025, Coherus Oncology, Inc. held its Annual Meeting of Stockholders virtually, where various proposals were voted on. The stockholders elected three Class II directors, ratified Ernst & Young LLP as the company’s accounting firm, approved executive compensation, and amended the 2014 Employee Stock Purchase Plan.

The most recent analyst rating on (CHRS) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on Coherus Biosciences stock, see the CHRS Stock Forecast page.

Product-Related AnnouncementsBusiness Operations and Strategy
Coherus Biosciences Rebrands to Coherus Oncology
Positive
May 30, 2025

On May 29, 2025, Coherus BioSciences, Inc. changed its name to Coherus Oncology, Inc. to better align with its focus on innovative cancer therapeutics. This strategic transformation underscores the company’s commitment to advancing its oncology pipeline, including FDA-approved treatments and promising candidates in clinical trials, aiming to set new standards in cancer care and improve patient outcomes.

The most recent analyst rating on (CHRS) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on Coherus Biosciences stock, see the CHRS Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 14, 2025