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Coherus Biosciences (CHRS)
NASDAQ:CHRS

Coherus Biosciences (CHRS) AI Stock Analysis

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Coherus Biosciences

(NASDAQ:CHRS)

Rating:45Neutral
Price Target:
$1.00
▲(25.00%Upside)
The overall stock score reflects significant financial challenges, including declining revenues and high leverage, which are major risk factors. While there are promising growth prospects from the oncology focus and recent corporate events, the technical analysis indicates bearish trends. The valuation remains unattractive due to negative earnings and lack of dividends. Strategic initiatives and cost-saving measures offer some positive outlook, but financial stability and market penetration remain crucial.
Positive Factors
Innovation Potential
The partial response in a heavily pretreated PD-1 refractory patient is an achievement, representing the potential of CHS-114 to potentially overcome PD-1 resistance.
Regulatory Momentum
The National Comprehensive Cancer Network (NCCN) revised guidelines include Loqtorzi as the preferred regimen.
Strategic Transition
Coherus has made significant positive progress as it has completed its transition to a novel oncology company, including what is considered an attractive sale of its biosimilar business, allowing the company to extinguish its debt and provide funding for the next ~18 months as it executes on driving Loqtorzi sales.
Negative Factors
Financial Performance
Q1 net revenue of $40MM was below our $55MM forecast.
Market Competition
Checkpoint inhibitors remain a crowded space dominated by some of the largest players in pharma, and Coherus' pipeline assets to pair with the PD1 are relatively early stage.
Revenue Growth Concerns
Sales of $7.3M in 1Q are expected to be greeted with disappointment by investors.

Coherus Biosciences (CHRS) vs. SPDR S&P 500 ETF (SPY)

Coherus Biosciences Business Overview & Revenue Model

Company DescriptionCoherus BioSciences, Inc. (CHRS) is a commercial-stage biopharmaceutical company focused on developing and commercializing biosimilar and innovative therapeutics. The company operates primarily in the healthcare sector, aiming to increase patient access to essential biologics. Coherus' core products include biosimilars for oncology and immunology treatments, offering more affordable options compared to branded biologics.
How the Company Makes MoneyCoherus BioSciences generates revenue primarily through the sale of its biosimilar products. The company's revenue model involves the development, manufacturing, and commercialization of biosimilars, which are essentially equivalent versions of existing biologic drugs that have lost patent protection. Key revenue streams include direct sales of these biosimilars to healthcare providers and distributors. Coherus also enters into strategic partnerships with other pharmaceutical companies to enhance its market reach and distribution capabilities, thereby contributing to its earnings. As patents of various branded biologics expire, Coherus capitalizes on these opportunities by introducing cost-effective biosimilar alternatives, thus driving its revenue growth.

Coherus Biosciences Earnings Call Summary

Earnings Call Date:May 12, 2025
(Q1-2025)
|
% Change Since: -21.57%|
Next Earnings Date:Jul 31, 2025
Earnings Call Sentiment Neutral
The earnings call presented a company in transition, highlighting strong growth prospects for LOQTORZI and promising clinical developments. However, challenges in market penetration and short-term revenue impacts due to restructuring were noted. Despite these challenges, the strategic focus on oncology and potential cost savings are positive indicators for future performance.
Q1-2025 Updates
Positive Updates
LOQTORZI Growth Prospects
LOQTORZI is projected to grow to about $150 million to $200 million annually over the next three years, providing non-dilutive funding for the development pipeline and becoming an important revenue source as indications expand.
Positive Clinical Developments
CHS-114 showed a 40% reduction in target lesions in a late-line head and neck cancer patient, indicating potential to address PD-1 resistance. Additionally, a 17% complete response rate was observed in a liver cancer trial with casdozokitug.
Strategic Partnerships and Indication Expansion
Several agreements are in place to expand indications for toripalimab, including collaborations with INOVIO for HPV-positive head and neck cancer, and Junshi for small cell lung cancer.
Successful Restructuring and Cost Savings
The company expects $25 million in annualized savings from a reduced headcount post-UDENYCA divestiture, with more than half already realized.
Negative Updates
Flat Revenue Despite Demand Growth
While patient demand for LOQTORZI grew 15% in Q1, revenue remained flat at $7.3 million due to a seasonal inventory drawdown.
Transition Challenges
The transition to a singular focus on LOQTORZI involved remapping territories and restructuring the sales force, which posed short-term headwinds.
Market Penetration Challenges
Despite the NCCN guidelines recommending LOQTORZI, some patients still receive non-preferred chemo-only and off-label IO treatments.
Continued Losses in Discontinued Operations
The net loss from discontinued operations was $9.2 million in the quarter, compared to a net income of $170.9 million in Q1 last year.
Company Guidance
During the Coherus BioSciences Q1 2025 earnings call, key guidance focused on the company's strategic shift to an innovative oncology business, highlighted by the FDA-approved PD-1 inhibitor LOQTORZI. The company projects LOQTORZI sales in nasopharyngeal carcinoma (NPC) to grow to $150 million to $200 million annually over the next three years, with a breakeven point of $15 million per quarter to cover commercial costs. Coherus is executing an indication expansion strategy for LOQTORZI, with multiple partnerships and pivotal trials in place to broaden its use across different cancer types. The call also emphasized the ongoing development of CHS-114 and casdozokitug, with clinical data readouts expected in 2025 supporting the advancement of these candidates. The company anticipates annualized savings of $25 million from headcount reductions following the UDENYCA divestiture and projects SG&A expenses for 2025 to be between $90 million and $100 million.

Coherus Biosciences Financial Statement Overview

Summary
Coherus Biosciences is facing significant financial challenges, with declining revenues, persistent net losses, and high leverage. The negative equity position and reliance on external financing highlight potential risks and financial instability.
Income Statement
45
Neutral
The income statement reveals significant challenges for Coherus Biosciences, with declining revenue and consistent net losses over the periods. The TTM data shows negative margins across gross profit, EBIT, and EBITDA, indicating profitability issues. Revenue growth is negative, reflecting a downward trend in sales.
Balance Sheet
30
Negative
The balance sheet indicates high financial leverage with a negative stockholders' equity, suggesting insolvency risks. The debt-to-equity ratio is not calculable due to negative equity, and the equity ratio is negative, underscoring financial instability. Overall, the balance sheet reflects potential risks due to high liabilities.
Cash Flow
40
Negative
Cash flow analysis shows limited operational cash generation with a marginally positive free cash flow in the TTM period. However, historical data reflects negative operating and free cash flows, indicating reliance on external financing. The operating cash flow to net income ratio is unfavorable, suggesting inefficiencies in cash conversion.
Breakdown
TTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
197.50M266.96M257.24M211.04M326.55M475.82M
Gross Profit
109.66M149.41M94.46M140.96M268.96M438.16M
EBIT
-114.58M-111.67M-203.20M-256.88M-263.86M156.32M
EBITDA
-98.76M60.94M-193.94M-255.58M-260.69M161.84M
Net Income Common Stockholders
-130.94M28.51M-237.89M-326.63M-306.32M132.24M
Balance SheetCash, Cash Equivalents and Short-Term Investments
125.99M125.99M117.75M191.68M417.19M541.16M
Total Assets
448.53M448.53M629.60M480.85M679.33M841.65M
Total Debt
269.90M269.90M480.84M471.06M408.28M404.02M
Net Debt
143.92M143.92M377.95M407.51M-8.91M-137.13M
Total Liabilities
580.52M580.52M823.03M618.26M581.61M560.67M
Stockholders Equity
-131.99M-131.99M-193.43M-137.42M97.73M280.97M
Cash FlowFree Cash Flow
500.00K-20.44M-175.17M-243.16M-38.72M147.09M
Operating Cash Flow
500.00K-20.44M-174.88M-241.12M-37.43M154.15M
Investing Cash Flow
10.07M230.32M144.64M-166.85M-138.41M-14.40M
Financing Cash Flow
-188.13M-186.97M69.60M54.33M51.88M223.95M

Coherus Biosciences Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.80
Price Trends
50DMA
0.90
Negative
100DMA
1.02
Negative
200DMA
1.10
Negative
Market Momentum
MACD
-0.04
Negative
RSI
44.13
Neutral
STOCH
49.99
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CHRS, the sentiment is Negative. The current price of 0.8 is below the 20-day moving average (MA) of 0.83, below the 50-day MA of 0.90, and below the 200-day MA of 1.10, indicating a bearish trend. The MACD of -0.04 indicates Negative momentum. The RSI at 44.13 is Neutral, neither overbought nor oversold. The STOCH value of 49.99 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CHRS.

Coherus Biosciences Risk Analysis

Coherus Biosciences disclosed 68 risk factors in its most recent earnings report. Coherus Biosciences reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 2 New Risks
1.
Risk Factor Summary Q3, 2024
2.
There are risks and uncertainties associated with the CIMERLI TSA and YUSIMRY TSA, one or more of which could have a material adverse effect on our business, financial condition, results of operations, cash flows or stock price. Q3, 2024

Coherus Biosciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (53)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
53
Neutral
$5.25B3.24-45.38%2.81%16.79%-0.06%
45
Neutral
$88.80M5.550.51%-34.58%-62.19%
SLSLS
43
Neutral
$157.65M-144.90%60.51%
41
Neutral
$96.86M-30.93%-1.20%
TITIL
34
Underperform
$196.14M-44.50%52.54%
33
Underperform
$96.98M-131.36%-100.00%9.16%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CHRS
Coherus Biosciences
0.80
-1.01
-55.80%
SLS
SELLAS Life Sciences Group
1.60
0.12
8.11%
NAUT
Nautilus Biotechnolgy
0.77
-1.81
-70.16%
TIL
Instil Bio
34.40
23.74
222.70%
GNLX
Genelux Corp.
2.45
-0.14
-5.41%

Coherus Biosciences Corporate Events

Product-Related AnnouncementsBusiness Operations and Strategy
Coherus Biosciences Rebrands to Coherus Oncology
Positive
May 30, 2025

On May 29, 2025, Coherus BioSciences, Inc. changed its name to Coherus Oncology, Inc. to better align with its focus on innovative cancer therapeutics. This strategic transformation underscores the company’s commitment to advancing its oncology pipeline, including FDA-approved treatments and promising candidates in clinical trials, aiming to set new standards in cancer care and improve patient outcomes.

The most recent analyst rating on (CHRS) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on Coherus Biosciences stock, see the CHRS Stock Forecast page.

Executive/Board ChangesShareholder Meetings
Coherus Biosciences Board Member Stolper Steps Down
Neutral
Apr 25, 2025

On April 22, 2025, Mark D. Stolper, a member of the Board of Directors at Coherus BioSciences, announced his decision not to stand for re-election at the company’s 2025 Annual Meeting of Stockholders. His departure is not due to any disagreements with the company, and he will continue to serve in a consulting role until the end of 2026. Following his decision, the board will reduce its size to nine directors. To ensure balanced representation among the board’s classes, on April 23, 2025, Rita A. Karachun and Michael Ryan were reclassified to different board classes, maintaining uninterrupted service while complying with the company’s Certificate of Incorporation.

Executive/Board ChangesM&A Transactions
Coherus Biosciences CCO Resigns After UDENYCA Divestiture
Neutral
Apr 22, 2025

Paul Reider, Coherus BioSciences’ Chief Commercial Officer, resigned effective April 30, 2025, following the company’s divestiture of its UDENYCA franchise. His departure is amicable, with no disagreements cited, and he will receive a compensation package including salary continuation and stock option extensions, while advising the company part-time until April 2026.

M&A TransactionsBusiness Operations and Strategy
Coherus Biosciences Completes UDENYCA Franchise Divestiture
Positive
Apr 14, 2025

On April 14, 2025, Coherus BioSciences announced the completion of its UDENYCA franchise divestiture to Intas Pharmaceuticals for up to $558.4 million. This strategic move, which included an upfront payment of $483.4 million, allows Coherus to focus on its oncology programs, reduce debt, and extend its cash runway into 2027, thereby strengthening its market position and operational focus on novel cancer therapies.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.