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PhoenixBio Co., Ltd. (JP:6190)
:6190
Japanese Market

PhoenixBio Co., Ltd. (6190) AI Stock Analysis

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JP:6190

PhoenixBio Co., Ltd.

(6190)

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Neutral 56 (OpenAI - 5.2)
Rating:56Neutral
Price Target:
¥460.00
▼(-4.96% Downside)
Action:ReiteratedDate:12/10/25
PhoenixBio Co., Ltd. shows strong technical momentum, which is the most significant positive factor. However, financial performance and valuation are concerning due to negative profitability and cash flow issues, as well as a negative P/E ratio. The absence of earnings call data and corporate events means these factors do not influence the score.
Positive Factors
Proprietary humanized model platform
PhoenixBio’s PXB humanized-mouse platform is a durable competitive asset used by pharma for ADME/PK and safety testing. High technical barriers and specialized know‑how create long-term customer stickiness, recurring demand for models and services, and differentiation versus generic CROs.
Fee-for-service and product revenue mix
A diversified revenue base—model sales/licensing plus fee‑for‑service studies—supports recurring contract work and multi-year customer relationships. This business mix can produce steady booking patterns and cross-sell opportunities, aiding predictable revenue over 2–6 months when operations are stable.
Relatively stable balance sheet
A healthy equity ratio and moderate leverage provide financial flexibility to fund operations or R&D despite near-term cash shortfalls. This structural balance reduces refinancing risk, enabling the firm to support platform maintenance and service capacity while working to restore operating cash flow.
Negative Factors
Negative operating cash flow
Sustained negative operating cash flow and free cash flow limit reinvestment in capacity and R&D, increasing dependence on external financing. Over months this constrains the firm’s ability to scale studies, maintain specialized colonies, and respond to larger client commitments without diluting liquidity.
Weak profitability and margins
Negative EBIT/EBITDA and net margins indicate structural operating inefficiencies or pricing pressure in core services. Persistently weak margins erode internal cash generation, make pricing power tenuous, and raise the bar for achieving sustainable profitability even if revenue growth resumes.
Declining EPS and earnings volatility
A nearly 48% decline in EPS signals meaningful earnings deterioration and volatile profitability. Such earnings instability complicates multi‑period planning, undermines retained earnings growth, and increases the risk that management must prioritize liquidity over strategic investments in platform expansion.

PhoenixBio Co., Ltd. (6190) vs. iShares MSCI Japan ETF (EWJ)

PhoenixBio Co., Ltd. Business Overview & Revenue Model

Company DescriptionPhoenixBio Co., Ltd. provides contract study services for drug discovery and development primarily in Japan. The company uses PXB-mouse, a chimeric mouse with a humanized liver for use in drug development experiments; and in vitro studies using fresh human hepatocytes taken from PXB-cells. The chimeric mouse model with a humanized liver is used for in vivo studies in gene therapeutics, NASH/NAFLD drug development programs, anti-viral therapeutic tests, DMPK/toxicity studies, and custom transplantations. The company was founded in 2002 and is headquartered in Higashihiroshima, Japan.
How the Company Makes MoneyPhoenixBio makes money primarily by monetizing its proprietary humanized animal model platform and related research offerings. Key revenue streams include: (1) Sales and licensing/usage fees for its humanized mouse models and associated biological materials (e.g., hepatocyte-related products) used in preclinical research; (2) Fee-for-service contract research, where the company conducts studies for customers (such as drug metabolism, pharmacokinetics, toxicity/safety, or other liver-related evaluations) using its in-house models and laboratory capabilities and charges study-based service fees; and (3) Other revenue related to providing research support and specialized testing tied to its platform. Specific details on the breakdown by segment, major customer concentration, or named strategic partnerships are null.

PhoenixBio Co., Ltd. Financial Statement Overview

Summary
PhoenixBio Co., Ltd. faces challenges in profitability and cash generation, with declining revenues and negative margins. The balance sheet is stable with moderate leverage, but the company's ability to generate cash from operations is concerning.
Income Statement
45
Neutral
PhoenixBio Co., Ltd. has experienced fluctuations in its revenue with a significant decline in 2025. Gross profit margins have been strong historically, but the company faced a negative EBIT and EBITDA margin in 2025, indicating operational challenges. Net profit margins have also been negative in recent years, reflecting ongoing profitability issues.
Balance Sheet
60
Neutral
The company's balance sheet shows a relatively stable equity base with a moderate debt-to-equity ratio. However, total assets have decreased over the years. The equity ratio remains healthy, suggesting that the company is not overly reliant on debt financing.
Cash Flow
50
Neutral
PhoenixBio's cash flow statement reveals negative operating cash flows in recent years, indicating challenges in generating cash from operations. Free cash flow has also been negative, which could constrain future growth investments. The operating cash flow to net income ratio has been unfavorable, reflecting the difficulty in converting profits into cash.
BreakdownTTMMar 2025Mar 2024Mar 2023Mar 2022Mar 2021
Income Statement
Total Revenue1.49B1.54B1.72B2.12B1.32B1.01B
Gross Profit1.09B1.11B1.20B1.56B727.79M588.14M
EBITDA-245.63M-396.12M87.94M537.42M-305.81M-167.27M
Net Income-448.70M-445.65M26.38M493.33M-387.97M-238.00M
Balance Sheet
Total Assets2.23B2.29B2.72B3.02B2.28B2.52B
Cash, Cash Equivalents and Short-Term Investments1.04B1.15B1.39B1.56B1.33B1.33B
Total Debt503.59M565.36M723.93M1.13B1.07B1.04B
Total Liabilities860.05M919.92M917.71M1.50B1.45B1.42B
Stockholders Equity1.37B1.37B1.80B1.51B828.15M1.09B
Cash Flow
Free Cash Flow0.00-94.24M-118.08M265.12M9.63M-284.23M
Operating Cash Flow0.00-73.00M-79.31M277.49M16.40M-101.91M
Investing Cash Flow0.00-27.98M115.36M-156.34M-6.97M-184.78M
Financing Cash Flow0.00-128.00M-244.88M86.63M-34.66M-160.19M

PhoenixBio Co., Ltd. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price484.00
Price Trends
50DMA
475.96
Negative
100DMA
486.76
Negative
200DMA
451.45
Negative
Market Momentum
MACD
-8.17
Positive
RSI
42.18
Neutral
STOCH
30.75
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:6190, the sentiment is Negative. The current price of 484 is above the 20-day moving average (MA) of 475.25, above the 50-day MA of 475.96, and above the 200-day MA of 451.45, indicating a bearish trend. The MACD of -8.17 indicates Positive momentum. The RSI at 42.18 is Neutral, neither overbought nor oversold. The STOCH value of 30.75 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:6190.

PhoenixBio Co., Ltd. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
¥4.74B-828.32-0.77%-288.43%
56
Neutral
¥15.73B120.781.24%-33.41%
56
Neutral
¥1.82B6.09-6.92%-144.96%
54
Neutral
¥25.79B-34.16-5.65%-469.19%
52
Neutral
¥138.00B-8.842.18%-0.16%-802.20%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
¥12.50B-8.14-42.49%-2.37%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:6190
PhoenixBio Co., Ltd.
447.00
65.00
17.02%
JP:2342
Trans Genic Inc.
281.00
102.00
56.98%
JP:4974
Takara Bio Inc.
1,146.00
308.75
36.88%
JP:4978
ReproCELL Inc.
166.00
5.00
3.11%
JP:7774
Japan Tissue Engineering Co., Ltd.
635.00
184.00
40.80%
JP:7776
CellSeed Inc.
325.00
-47.00
-12.63%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 10, 2025