tiprankstipranks
Chiome Bioscience Inc. (JP:4583)
:4583
Japanese Market

Chiome Bioscience Inc. (4583) AI Stock Analysis

2 Followers

Top Page

JP:4583

Chiome Bioscience Inc.

(4583)

Select Model
Select Model
Select Model
Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
¥101.00
▼(-4.72% Downside)
Action:ReiteratedDate:02/21/26
The score is constrained primarily by weak financial performance—persistent large losses and ongoing cash burn—despite modest leverage. Technicals are neutral-to-slightly constructive near term but remain below longer-term averages, and valuation is limited by negative earnings (negative P/E) with no dividend yield data.
Positive Factors
Gross Margin Durability
Sustained gross margins near 55–60% indicate the company’s core R&D and discovery activities retain value capture potential. In biotech, strong product-level margins support long-term partner economics and make licensing or royalty monetization more viable as programs advance.
Negative Factors
Persistent Cash Burn
Consistent negative operating and free cash flow show the company’s losses translate into real cash outflows, increasing dependence on external financing or partner deals. Over months, persistent burn elevates dilution and execution risk if new funding or milestone receipts are delayed.
Read all positive and negative factors
Positive Factors
Negative Factors
Gross Margin Durability
Sustained gross margins near 55–60% indicate the company’s core R&D and discovery activities retain value capture potential. In biotech, strong product-level margins support long-term partner economics and make licensing or royalty monetization more viable as programs advance.
Read all positive factors

Chiome Bioscience Inc. (4583) vs. iShares MSCI Japan ETF (EWJ)

Chiome Bioscience Inc. Business Overview & Revenue Model

Company Description
Chiome Bioscience Inc. engages in the research and development of drug discovery technology platforms worldwide. The company operates through two segments, Drug Discovery Business and Drug Discovery Support Business. It offers ADLib System, a mono...
How the Company Makes Money
Chiome Bioscience primarily generates revenue through biopharmaceutical R&D monetization rather than high-volume product sales. Key revenue streams typically include (1) licensing out its drug candidates and/or proprietary technologies to pharmace...

Chiome Bioscience Inc. Financial Statement Overview

Summary
Overall fundamentals are weak: revenue is volatile with a recent decline, the company remains deeply unprofitable with very large net losses versus revenue, and operating/free cash flow are consistently negative (cash burn persists). Balance sheet leverage is modest, but ongoing losses raise risk of continued equity erosion and funding needs.
Income Statement
18
Very Negative
Balance Sheet
54
Neutral
Cash Flow
16
Very Negative
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue768.88M593.29M780.81M682.46M630.82M712.93M
Gross Profit436.96M355.58M432.02M397.72M347.78M420.59M
EBITDA-985.98M-976.03M-1.03B-1.20B-1.26B-1.33B
Net Income-997.11M-982.78M-1.02B-1.22B-1.24B-1.48B
Balance Sheet
Total Assets1.96B1.73B2.47B1.75B2.22B2.34B
Cash, Cash Equivalents and Short-Term Investments1.47B1.21B2.06B1.33B1.73B1.79B
Total Debt260.50M261.70M281.50M291.00M184.00M183.00M
Total Liabilities443.39M605.44M548.55M593.73M424.72M446.39M
Stockholders Equity1.52B1.12B1.92B1.16B1.79B1.89B
Cash Flow
Free Cash Flow0.00-976.07M-1.00B0.00-1.19B0.00
Operating Cash Flow0.00-935.99M-1.00B-1.07B-1.19B-1.13B
Investing Cash Flow0.00-55.46M0.00173.00K0.00-35.38M
Financing Cash Flow0.00133.20M1.74B667.30M1.13B271.35M

Chiome Bioscience Inc. Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price106.00
Price Trends
50DMA
109.48
Negative
100DMA
112.43
Negative
200DMA
126.08
Negative
Market Momentum
MACD
-1.80
Negative
RSI
45.70
Neutral
STOCH
26.67
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4583, the sentiment is Neutral. The current price of 106 is above the 20-day moving average (MA) of 105.45, below the 50-day MA of 109.48, and below the 200-day MA of 126.08, indicating a bearish trend. The MACD of -1.80 indicates Negative momentum. The RSI at 45.70 is Neutral, neither overbought nor oversold. The STOCH value of 26.67 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for JP:4583.

Chiome Bioscience Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
72
Outperform
¥14.02B41.4012.91%37.96%
55
Neutral
¥75.68B-20.18-9.04%13.09%
54
Neutral
¥20.74B87.609.87%-24.41%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
¥91.85B-5.96-19.31%-1.96%-64.18%
47
Neutral
¥7.56B-7.3925.28%39.15%
46
Neutral
¥167.48B-57.13-10.16%-62.47%-134.06%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4583
Chiome Bioscience Inc.
104.00
-17.00
-14.05%
JP:4587
Peptidream
1,290.00
-468.00
-26.62%
JP:4565
Sosei Group
1,015.00
328.00
47.74%
JP:4570
Immuno-Biological Laboratories Co., Ltd.
1,505.00
1,094.76
266.86%
JP:4579
RaQualia Pharma Inc.
848.00
537.00
172.67%
JP:4588
Oncolys BioPharma, Inc.
2,587.00
2,105.00
436.72%

Chiome Bioscience Inc. Corporate Events

Chiome Bioscience Corrects FY2025 Results as Losses and Cash Burn Persist
Mar 27, 2026
Chiome Bioscience has issued an updated version of its non-consolidated financial results for the fiscal year ended December 31, 2025, correcting specific items related to share count, cash flow statements, segment information, and per-share data....
Chiome Bioscience Outlines FY2025 Results and mAb Development Focus
Feb 10, 2026
Chiome Bioscience has released supplementary information on its financial results for the fiscal year ending December 2025, outlining both performance metrics and operational highlights. The materials emphasize its ongoing drive to speed up discov...
Chiome Bioscience Widens Cash Burn as Sales Drop and Outlook Stays Limited
Feb 10, 2026
Chiome Bioscience reported a ninth consecutive annual loss for the fiscal year ended December 31, 2025, as net sales fell 24.0% to ¥593 million and net loss narrowed slightly to ¥982 million, with profitability metrics remaining deeply n...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 21, 2026