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Oncolys BioPharma, Inc. (JP:4588)
:4588
Japanese Market

Oncolys BioPharma, Inc. (4588) AI Stock Analysis

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JP:4588

Oncolys BioPharma, Inc.

(4588)

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Neutral 55 (OpenAI - 5.2)
Rating:55Neutral
Price Target:
¥2,335.00
▲(145.02% Upside)
Action:ReiteratedDate:03/03/26
The score is held down primarily by weak financial performance—collapsed revenue, persistent large losses, and heavy cash burn—despite a relatively manageable balance sheet. Strong technical momentum lifts the score, while valuation remains constrained by loss-making economics and no dividend support.
Positive Factors
Balance Sheet Strength
Improved leverage and a meaningful rise in equity and assets provide structural liquidity and runway. This reduces near-term refinancing pressure, allows continued clinical R&D funding without immediate solvency stress, and preserves strategic optionality over the coming months.
Negative Factors
Severe Revenue Decline
The dramatic multi-year revenue collapse removes an internal funding base and signals failure to scale commercial or licensing revenue. Structurally low top-line undermines long-term sustainability and forces dependence on external capital or a transformative commercial/clinical success to restore viability.
Read all positive and negative factors
Positive Factors
Negative Factors
Balance Sheet Strength
Improved leverage and a meaningful rise in equity and assets provide structural liquidity and runway. This reduces near-term refinancing pressure, allows continued clinical R&D funding without immediate solvency stress, and preserves strategic optionality over the coming months.
Read all positive factors

Oncolys BioPharma, Inc. (4588) vs. iShares MSCI Japan ETF (EWJ)

Oncolys BioPharma, Inc. Business Overview & Revenue Model

Company Description
Oncolys BioPharma Inc. engages in the research, development, manufacture, sale, import, and export of oncolytic viruses, drugs and medicines, and tumor diagnostic agents in Japan, the rest of Asia, and the United States. Its product pipeline inclu...
How the Company Makes Money
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Oncolys BioPharma, Inc. Financial Statement Overview

Summary
Financials are weak overall: revenue has fallen sharply from 2022 levels and remains very low, while operating and net losses are large and persistent. Cash flow is a major risk with heavy, recurring operating cash outflows and negative free cash flow, implying reliance on external financing. The main offset is a comparatively manageable balance sheet with modest leverage and higher equity/assets, providing some flexibility despite ongoing loss-driven erosion risk.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
21
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue28.55M28.55M31.38M63.04M976.18M642.49M
Gross Profit27.68M28.30M31.38M30.61M338.49M198.80M
EBITDA-2.18B-2.05B-1.68B-1.93B-1.14B-1.60B
Net Income-2.24B-2.06B-1.68B-1.94B-1.15B-1.62B
Balance Sheet
Total Assets1.93B4.56B3.20B2.04B2.65B4.29B
Cash, Cash Equivalents and Short-Term Investments1.39B3.72B2.41B1.53B1.71B3.45B
Total Debt366.79M320.02M324.64M315.17M393.66M503.47M
Total Liabilities493.35M555.91M446.65M566.50M491.69M697.88M
Stockholders Equity1.44B4.00B2.75B1.47B2.16B3.59B
Cash Flow
Free Cash Flow0.00-1.94B-2.02B-1.34B-1.72B-1.74B
Operating Cash Flow0.00-1.94B-2.02B-1.34B-1.72B-1.74B
Investing Cash Flow0.00-7.58M-4.71M-5.39M20.12M-942.00K
Financing Cash Flow0.003.22B2.88B1.14B-113.83M3.09B

Oncolys BioPharma, Inc. Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price953.00
Price Trends
50DMA
2303.24
Positive
100DMA
1712.10
Positive
200DMA
1183.55
Positive
Market Momentum
MACD
-17.02
Positive
RSI
47.01
Neutral
STOCH
39.59
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4588, the sentiment is Neutral. The current price of 953 is below the 20-day moving average (MA) of 2649.70, below the 50-day MA of 2303.24, and below the 200-day MA of 1183.55, indicating a neutral trend. The MACD of -17.02 indicates Positive momentum. The RSI at 47.01 is Neutral, neither overbought nor oversold. The STOCH value of 39.59 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for JP:4588.

Oncolys BioPharma, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
55
Neutral
¥68.40B-17.30-9.04%13.09%
52
Neutral
¥138.24B-8.842.18%-0.16%-802.20%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
¥14.73B-17.9614.03%
47
Neutral
¥7.44B-7.3925.28%39.15%
46
Neutral
¥155.34B-57.13-10.16%-62.47%-134.06%
46
Neutral
¥8.44B-7.89-63.25%99.87%40.60%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4588
Oncolys BioPharma, Inc.
2,338.00
1,718.00
277.10%
JP:4587
Peptidream
1,196.50
-980.50
-45.04%
JP:4564
OncoTherapy Science
22.00
-6.00
-21.43%
JP:4575
CanBas Co., Ltd.
747.00
-213.00
-22.19%
JP:4583
Chiome Bioscience Inc.
105.00
-40.00
-27.59%
JP:4974
Takara Bio Inc.
1,148.00
320.00
38.65%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 03, 2026