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Oncolys BioPharma, Inc. (JP:4588)
:4588
Japanese Market
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Oncolys BioPharma, Inc. (4588) AI Stock Analysis

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JP:4588

Oncolys BioPharma, Inc.

(4588)

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Neutral 41 (OpenAI - 4o)
Rating:41Neutral
Price Target:
¥590.00
▼(-4.53% Downside)
Oncolys BioPharma, Inc. receives a low overall score due to significant financial challenges, including declining revenues and persistent losses. Technical indicators show weak momentum, and valuation metrics are poor with a negative P/E ratio. The lack of earnings call data and corporate events further limits positive influences on the score.

Oncolys BioPharma, Inc. (4588) vs. iShares MSCI Japan ETF (EWJ)

Oncolys BioPharma, Inc. Business Overview & Revenue Model

Company DescriptionOncolys BioPharma Inc. engages in the research, development, manufacture, sale, import, and export of oncolytic viruses, drugs and medicines, and tumor diagnostic agents in Japan, the rest of Asia, and the United States. Its product pipeline includes Telomelysin (OBP-301), an oncolytic adenovirus that is in phase II clinical trial for the treatment of gastric cancer/gastroesophageal junction, head and neck, and esophageal cancers; and in phase I clinical trial for the treatment of hepatocellular carcinoma. The company's product pipeline also includes OBP-702, a telomerase-specific oncolytic adenovirus, which is in pre-clinical trial for the treatment of solid tumors; OBP-2011, which is in pre-clinical trial for the treatment of SARS-Cov-2 virus infection; OBP-601 (Censavudine), a nucleotide reverse transcriptase inhibitor that has completed the phase IIb clinical trial for the treatment of HIV infection; and OBP-801, a histone deacetylase inhibitor, which is in phase I clinical trial for the treatment of solid tumors, as well as in pre-clinical trial for ophthalmic use. In addition, it develops TelomeScan (OBP-401 and OBP-1101), a cancer detection drug, for detecting living circulating tumor cells in blood from cancer patients. Further, the company provides diagnostic drugs and inspection services. It has various licensing agreements with Okayama University, Osaka University, Kyoto Prefectural University of Medicine, Kagoshima University, Astellas Pharma Inc., Yale University, Biologics Consulting Group, Inc., Lonza Houston, Inc., Medigen Biotechnology Corp., and Liquid Biotech USA, Inc. Oncolys BioPharma Inc. was incorporated in 2004 and is headquartered in Tokyo, Japan.
How the Company Makes MoneyOncolys BioPharma, Inc. generates revenue primarily through research and development collaborations, licensing agreements, and potential milestone payments related to its drug candidates. The company engages in strategic partnerships with larger pharmaceutical firms to jointly develop and commercialize its therapeutic products, which can provide upfront payments, research funding, and potential royalties on sales. Additionally, Oncolys may earn income from government grants and subsidies aimed at supporting innovative biopharmaceutical research. Although the company is still in the development stage, its long-term revenue growth relies on successfully bringing its drug candidates to market, thereby initiating product sales and generating licensing income.

Oncolys BioPharma, Inc. Financial Statement Overview

Summary
Oncolys BioPharma, Inc. faces serious financial challenges characterized by declining revenues, persistent losses, and negative cash flows. While the balance sheet shows strong equity, the overarching issue is the inability to achieve profitability and positive cash flow, posing risks to long-term viability.
Income Statement
20
Very Negative
Oncolys BioPharma, Inc. has experienced significant revenue decline, with a drop from 2022 to 2023 and further to 2024. The company has consistently operated at a loss, with negative EBIT and net income margins, reflecting challenges in scaling profitable operations.
Balance Sheet
30
Negative
The company maintains a healthy equity position with a strong equity ratio, indicative of solid capitalization. However, the continued losses affect return on equity negatively. While debt levels are manageable, the lack of profitability is concerning for long-term stability.
Cash Flow
25
Negative
Operating and free cash flow have remained negative, indicating ongoing operational cash burn. Despite positive financing cash flow, likely from fundraising, the inability to generate positive cash flow from operations is a critical risk.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue31.38M31.38M63.04M976.18M642.49M314.18M
Gross Profit30.56M31.38M30.61M338.49M198.80M236.11M
EBITDA-2.09B-1.68B-1.93B-1.14B-1.60B-2.08B
Net Income-2.13B-1.68B-1.94B-1.15B-1.62B-2.10B
Balance Sheet
Total Assets2.31B3.20B2.04B2.65B4.29B2.80B
Cash, Cash Equivalents and Short-Term Investments1.74B2.41B1.53B1.71B3.45B2.07B
Total Debt288.78M324.64M315.17M393.66M503.47M525.08M
Total Liabilities373.88M446.65M566.50M491.69M697.88M793.09M
Stockholders Equity1.94B2.75B1.47B2.16B3.59B2.00B
Cash Flow
Free Cash Flow0.00-2.02B-1.34B-1.72B-1.74B-1.47B
Operating Cash Flow0.00-2.02B-1.34B-1.72B-1.74B-1.47B
Investing Cash Flow0.00-4.71M-5.39M20.12M-942.00K-37.58M
Financing Cash Flow0.002.88B1.14B-113.83M3.09B242.26M

Oncolys BioPharma, Inc. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price618.00
Price Trends
50DMA
636.38
Negative
100DMA
616.73
Positive
200DMA
609.70
Positive
Market Momentum
MACD
-7.87
Positive
RSI
45.60
Neutral
STOCH
40.25
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4588, the sentiment is Negative. The current price of 618 is below the 20-day moving average (MA) of 633.50, below the 50-day MA of 636.38, and above the 200-day MA of 609.70, indicating a neutral trend. The MACD of -7.87 indicates Positive momentum. The RSI at 45.60 is Neutral, neither overbought nor oversold. The STOCH value of 40.25 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4588.

Oncolys BioPharma, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
66
Neutral
11.48B-229.223.94%0.86%-13.81%-107.95%
50
Neutral
12.35B-91.02-4.39%268.05%83.57%
48
Neutral
9.12B-8.5530.92%26.00%
47
Neutral
14.19B-24.80-8.37%40.66%24.86%
47
Neutral
18.83B-9.735.59%
41
Neutral
¥16.08B-9.04%2.12%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4588
Oncolys BioPharma, Inc.
622.00
56.00
9.89%
JP:4579
RaQualia Pharma Inc.
580.00
51.00
9.64%
JP:4583
Chiome Bioscience Inc.
133.00
11.00
9.02%
JP:4599
StemRIM Inc.
303.00
-108.00
-26.28%
JP:4880
CellSource Co., Ltd.
579.00
-665.74
-53.48%
JP:4888
STELLA PHARMA CORPORATION
363.00
-171.00
-32.02%

Oncolys BioPharma, Inc. Corporate Events

Oncolys BioPharma Reports Increased Losses in H1 2025
Aug 8, 2025

Oncolys BioPharma Inc. reported its non-consolidated financial results for the first half of 2025, revealing a decline in net sales and increased losses compared to the previous year. The company’s net sales dropped to 28 million yen, with operating and ordinary profits showing significant negative figures. Despite the challenging financial performance, the company maintains a strong equity ratio, although its total assets and net assets have decreased. The financial results indicate ongoing challenges in the company’s operations, which may impact its market positioning and stakeholder confidence.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 26, 2025