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CanBas Co., Ltd. (JP:4575)
:4575
Japanese Market

CanBas Co., Ltd. (4575) AI Stock Analysis

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JP:4575

CanBas Co., Ltd.

(4575)

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Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
¥895.00
▲(13.72% Upside)
The score is primarily constrained by weak financial performance driven by ongoing losses and cash burn, only partly offset by a cleaner, better-capitalized balance sheet with zero reported debt. Technical signals remain mixed with the stock below key longer-term moving averages and a negative MACD, while valuation is challenging due to negative earnings and no dividend yield data.
Positive Factors
Debt-free balance sheet
A reported zero debt position across 2023–2025 materially reduces leverage risk and interest obligations, improving financial flexibility. For a small R&D biotech this extends runway and strengthens negotiating power with partners and potential acquirers over the next several quarters.
Material equity capitalization improvement
Sharp growth in equity provides a more durable capital base to fund R&D and absorb ongoing losses without immediate refinancing. Stronger capitalization lowers short-term solvency risk and supports continued clinical progress and partnering discussions over the coming 2–6 months.
Partnership/licensing-focused business model
A partnership/licensing model lets the company monetize R&D via upfront, milestone, and royalty payments while sharing development and commercialization risk. For a small biotech, this durable model can conserve cash and scale commercialization through larger partners if clinical progress continues.
Negative Factors
Persistent cash burn
Consistent negative operating and free cash flow forces ongoing external funding needs. Even with some improvement (2025 OCF/FCC ~-¥0.77bn vs ~-¥1.28bn in 2024), continued cash burn risks dilution, project slowdowns, or constrained R&D sequencing absent partner funding.
Effectively no recent revenue
With near-zero product revenue the company remains pre-commercial and dependent on milestones or fundraising. This creates persistent uncertainty around sustainable cash generation and makes long-term operational planning and reinvestment contingent on pipeline outcomes or external partners.
Negative returns on equity and value erosion
A roughly -39% ROE indicates shareholders' capital has not produced sustainable economic returns, reflecting ongoing operating losses. Over months this elevates governance and financing risks, as continued value erosion can pressure ability to attract favorable partner deals or non-dilutive funding.

CanBas Co., Ltd. (4575) vs. iShares MSCI Japan ETF (EWJ)

CanBas Co., Ltd. Business Overview & Revenue Model

Company DescriptionCanBas Co., Ltd., a clinical stage biopharmaceutical company, develops therapeutics for cancer patients. It develops CBP501, a calmodulin-modulating peptide to treat various cancer; and CBS9106, a reversible exportin-1inhibitor that is in Phase I clinical trial for the treatment of solid tumors. The company has a collaboration alliance with Stemline Therapeutics, Inc. CanBas Co., Ltd. was incorporated in 2000 and is based in Numazu, Japan.
How the Company Makes MoneyCanBas Co., Ltd. generates revenue primarily through the successful development and commercialization of its pharmaceutical products and technologies. The company invests in research and development to create proprietary drugs, which it can then license to larger pharmaceutical companies or bring to market itself. Revenue streams include milestone payments from licensing agreements, royalties from drug sales, and potentially direct sales of its pharmaceutical products. Additionally, strategic partnerships and collaborations with other biotech or pharmaceutical firms play a crucial role in its revenue model, providing both financial support and access to broader markets for its developed therapies.

CanBas Co., Ltd. Financial Statement Overview

Summary
Financials reflect a development-stage biotech profile: income statement is weak with effectively zero recent revenue and persistent operating/net losses, and cash flow shows ongoing negative operating/free cash flow (cash burn), though burn improved in the latest year. The balance sheet is a relative strength with zero reported debt (2023–2025) and materially higher equity, reducing leverage risk, but returns remain strongly negative.
Income Statement
8
Very Negative
The income statement shows persistent operating losses and net losses across all reported years, with gross profit also negative—consistent with a pre-commercial biotech still funding R&D rather than generating product revenue. Revenue has fallen to effectively zero in recent years (vs. ~¥109–110m in 2020–2021), and profitability has not yet stabilized, keeping overall earnings quality and visibility weak. A modest positive is that the latest annual net loss (2025) is slightly narrower than 2023–2024, but the business remains firmly loss-making.
Balance Sheet
62
Positive
The balance sheet looks comparatively healthier: total debt is reported at zero from 2023–2025, and equity has increased materially (from ~¥0.25bn in 2022 to ~¥2.94bn in 2025), indicating improved capitalization and reduced leverage risk versus earlier years when debt-to-equity was high (>1x in 2021–2022 and >3x in 2020). The key weakness is ongoing value erosion from losses, reflected in consistently negative returns on equity (still about -39% in 2025), meaning shareholders’ capital is not yet generating sustainable returns.
Cash Flow
18
Very Negative
Cash flow remains a major pressure point: operating cash flow and free cash flow are negative every year shown, indicating continuing cash burn to fund operations. There is some improvement in the latest year (2025 operating/free cash flow of about -¥0.77bn vs. about -¥1.28bn in 2024), but the company is still not self-funding and will likely remain dependent on external financing until revenue traction improves.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.00108.94M
Gross Profit-820.00M-820.00M-984.00M-671.00M-608.00M-322.00M
EBITDA-1.16B-1.16B53.65M-1.28B-848.65M-522.28M
Net Income-1.16B-1.16B-1.21B-1.24B-855.58M-531.03M
Balance Sheet
Total Assets3.05B3.05B2.43B2.09B790.71M1.30B
Cash, Cash Equivalents and Short-Term Investments2.83B2.83B1.89B1.62B737.77M1.15B
Total Debt0.000.000.000.00367.34M749.99M
Total Liabilities107.00M107.00M91.99M153.85M540.02M857.64M
Stockholders Equity2.94B2.94B2.34B1.93B250.69M437.97M
Cash Flow
Free Cash Flow0.00-771.45M-1.28B-1.40B-719.81M-688.57M
Operating Cash Flow0.00-771.45M-1.28B-1.40B-719.81M-688.57M
Investing Cash Flow0.00122.00K0.000.00182.00K0.00
Financing Cash Flow0.001.75B1.54B2.27B282.75M728.80M

CanBas Co., Ltd. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price787.00
Price Trends
50DMA
828.96
Positive
100DMA
920.93
Negative
200DMA
989.63
Negative
Market Momentum
MACD
10.80
Positive
RSI
53.30
Neutral
STOCH
27.60
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4575, the sentiment is Positive. The current price of 787 is below the 20-day moving average (MA) of 860.95, below the 50-day MA of 828.96, and below the 200-day MA of 989.63, indicating a neutral trend. The MACD of 10.80 indicates Positive momentum. The RSI at 53.30 is Neutral, neither overbought nor oversold. The STOCH value of 27.60 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:4575.

CanBas Co., Ltd. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
¥21.93B-47.52-5.65%-469.19%
52
Neutral
¥11.60B-10.60-42.49%-2.37%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
¥17.17B-13.9214.03%
46
Neutral
¥19.61B542.68-32.68%
45
Neutral
¥44.21B-9.72-82.33%47.73%
43
Neutral
¥18.18B-9.5011.34%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4575
CanBas Co., Ltd.
871.00
8.00
0.93%
JP:4593
Healios KK
382.00
110.00
40.44%
JP:4599
StemRIM Inc.
290.00
-23.00
-7.35%
JP:4889
Renascience Inc.
1,480.00
55.00
3.86%
JP:7774
Japan Tissue Engineering Co., Ltd.
540.00
71.00
15.14%
JP:7776
CellSeed Inc.
315.00
-53.00
-14.40%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 30, 2025