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Healios KK (JP:4593)
:4593
Japanese Market

Healios KK (4593) AI Stock Analysis

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JP:4593

Healios KK

(4593)

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Underperform 38 (OpenAI - 4o)
Rating:38Underperform
Price Target:
¥286.00
▼(-5.92% Downside)
Healios KK's overall stock score is primarily impacted by its weak financial performance, characterized by declining revenues and high leverage. Technical analysis suggests bearish momentum, although oversold conditions may offer a potential short-term rebound. Valuation metrics are unattractive due to negative profitability and lack of dividends.
Positive Factors
Free Cash Flow Growth
Positive free cash flow growth indicates potential for future investment and operational flexibility, supporting long-term sustainability.
Strategic Partnerships
Strategic partnerships enhance credibility and market reach, providing financial support and aiding in product development and commercialization.
Innovative Therapies
Innovative therapies in regenerative medicine position the company to address significant market needs, potentially driving long-term growth.
Negative Factors
Declining Revenue
Declining revenue growth undermines financial stability and limits the company's ability to invest in future growth opportunities.
High Leverage
High leverage increases financial risk, potentially impacting the company's ability to manage debt and invest in strategic initiatives.
Negative Profitability Margins
Negative profitability margins reflect operational inefficiencies and financial distress, hindering long-term growth and shareholder value.

Healios KK (4593) vs. iShares MSCI Japan ETF (EWJ)

Healios KK Business Overview & Revenue Model

Company DescriptionHealios KK (4593) is a biotechnology company based in Japan that focuses on the research, development, and commercialization of innovative therapies and solutions for various medical conditions. The company primarily operates in the healthcare sector, with a strong emphasis on regenerative medicine and cell therapy. Healios aims to address unmet medical needs through its core products, which include advanced treatments for neurological disorders, cancer, and other serious illnesses, leveraging cutting-edge technologies and scientific research.
How the Company Makes MoneyHealios KK generates revenue through several key streams, primarily by developing and commercializing its proprietary therapies and treatments. The company partners with pharmaceutical firms and research institutions to further its product development and clinical trials, which can lead to milestone payments and royalties upon successful commercialization of its therapies. Additionally, Healios may receive funding through public and private grants aimed at supporting innovative health solutions. The company's strategic collaborations and partnerships are significant contributors to its financial performance, as they not only provide necessary funding but also enhance the company's credibility and market reach.

Healios KK Financial Statement Overview

Summary
Healios KK is facing significant financial difficulties, with declining revenues, substantial losses, and high leverage. The income statement, balance sheet, and cash flow analyses all indicate severe financial challenges.
Income Statement
20
Very Negative
Healios KK's income statement reveals significant challenges. The company has experienced a dramatic decline in revenue, with a negative growth rate of 80.95% in the TTM period. Profitability metrics are concerning, with negative net profit margins and EBIT margins indicating substantial losses. The gross profit margin has also deteriorated, reflecting operational inefficiencies.
Balance Sheet
30
Negative
The balance sheet shows a high debt-to-equity ratio, suggesting significant leverage and potential financial risk. Return on equity is negative, indicating that the company is not generating returns for shareholders. The equity ratio is relatively low, which may impact financial stability.
Cash Flow
25
Negative
Cash flow analysis highlights ongoing cash flow challenges, with negative operating and free cash flows. The free cash flow to net income ratio is slightly above 1, indicating that free cash flow is not sufficient to cover net losses. The company has shown some improvement in free cash flow growth, but overall cash flow health remains weak.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue97.00M560.00M121.00M90.00M41.00M27.00M
Gross Profit-278.00M432.00M108.00M90.00M41.00M27.00M
EBITDA-1.09B-2.54B-3.16B-4.52B-3.61B-3.97B
Net Income-3.89B-4.24B-3.82B-5.17B-4.91B-5.51B
Balance Sheet
Total Assets17.33B14.19B15.15B15.03B23.97B23.17B
Cash, Cash Equivalents and Short-Term Investments6.50B3.67B6.72B7.25B15.13B13.92B
Total Debt2.63B2.66B4.53B7.15B11.96B11.40B
Total Liabilities14.37B12.11B11.29B10.65B15.33B15.32B
Stockholders Equity2.94B2.06B3.86B4.38B8.64B7.84B
Cash Flow
Free Cash Flow-2.98B-1.83B-2.85B-4.86B-5.39B-4.26B
Operating Cash Flow-2.90B-1.82B-2.82B-4.60B-5.09B-3.94B
Investing Cash Flow-1.59B-1.42B-1.12B-909.00M-736.00M-1.22B
Financing Cash Flow6.41B77.00M3.34B-2.50B6.99B803.00M

Healios KK Technical Analysis

Technical Analysis Sentiment
Negative
Last Price304.00
Price Trends
50DMA
443.72
Negative
100DMA
506.87
Negative
200DMA
440.81
Negative
Market Momentum
MACD
-46.91
Positive
RSI
33.59
Neutral
STOCH
24.20
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4593, the sentiment is Negative. The current price of 304 is below the 20-day moving average (MA) of 392.95, below the 50-day MA of 443.72, and below the 200-day MA of 440.81, indicating a bearish trend. The MACD of -46.91 indicates Positive momentum. The RSI at 33.59 is Neutral, neither overbought nor oversold. The STOCH value of 24.20 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4593.

Healios KK Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
¥18.68B-46.55-5.65%-469.19%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
¥13.93B-49.971.24%-33.41%
47
Neutral
¥16.30B-8.5211.34%
43
Neutral
¥8.46B-8.21-42.49%-2.37%
38
Underperform
¥35.10B-7.73-82.33%47.73%
33
Underperform
¥48.56B-72.401772.85%16.16%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4593
Healios KK
304.00
134.00
78.82%
JP:4599
StemRIM Inc.
260.00
-45.00
-14.75%
JP:4894
Cuorips Inc.
5,890.00
1,150.00
24.26%
JP:4978
ReproCELL Inc.
147.00
47.00
47.00%
JP:7774
Japan Tissue Engineering Co., Ltd.
460.00
25.00
5.75%
JP:7776
CellSeed Inc.
244.00
-164.00
-40.20%

Healios KK Corporate Events

Healios K.K. Releases FY2025 Q3 Financial Results
Nov 13, 2025

Healios K.K. has released its financial results for the third quarter of fiscal year 2025. The announcement provides insights into the company’s current financial standing and strategic direction, which could impact its operations and market position in the regenerative medicine sector. Stakeholders should consider the potential implications of these results on future company performance.

Healios Partners with Kyushu University for Brain Tumor Therapy Research
Oct 14, 2025

Healios K.K. has entered into a joint research agreement with Kyushu University’s Department of Neurosurgery to study the use of CAR-eNK cells in treating brain tumors. This collaboration aims to evaluate the antitumor effects of these genetically modified cells, potentially enhancing cancer treatment options and reinforcing Healios’ position in the regenerative medicine industry.

Healios Ends Alliance with Nikon, Plans CDMO Expansion
Oct 14, 2025

Healios K.K. has announced the termination of its business and capital alliance with Nikon Corporation, initially formed to promote regenerative medicine commercialization. The decision follows a strategic reassessment by both companies, leading them to pursue independent paths. Healios plans to expand its operations as a Contract Development and Manufacturing Organization (CDMO) in 2025, focusing on regenerative and cellular medicine, with no expected impact on its 2025 financial results.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 18, 2025