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Cuorips Inc. (JP:4894)
:4894
Japanese Market

Cuorips Inc. (4894) AI Stock Analysis

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JP:4894

Cuorips Inc.

(4894)

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Neutral 55 (OpenAI - 5.2)
Rating:55Neutral
Price Target:
¥8,241.00
▲(32.28% Upside)
The score is held back primarily by persistent heavy losses and significant cash burn, despite strong revenue growth and a debt-free balance sheet that provides runway. Technicals are supportive due to a strong uptrend, but overbought signals temper the near-term outlook. Valuation is also constrained by negative earnings and no provided dividend yield.
Positive Factors
Rapid Revenue Growth
Steep revenue expansion indicates genuine commercial traction and expanding market acceptance of products. Over a 2-6 month horizon this growth underpins scale benefits, supports broader customer adoption, and provides a foundation for future operating leverage if cost growth is controlled.
Healthy Gross Margin
A ~52% gross margin reflects strong unit economics and pricing power for core offerings. Sustained margin levels give the business structural capacity to absorb SG&A and R&D as it scales, improving odds of eventual profitability once fixed costs are leveraged over larger revenue.
Conservative Balance Sheet
A debt-free, equity-funded balance sheet provides meaningful financial flexibility and lowers refinancing risk. This structural strength lengthens runway to execute strategic initiatives, supports R&D and commercialization spend, and reduces short-term liquidity pressure from interest obligations.
Negative Factors
Large Cash Burn
Consistently large negative operating and free cash flow denotes a high burn profile that erodes reserves and raises funding risk. Over months this increases likelihood of dilutive capital raises or cutbacks, constraining investment in commercialization and product development.
Sustained Operating Losses
Deep and persistent operating losses show the current cost structure outpaces revenue, signaling an unclear path to break-even absent material margin improvement. Structurally, ongoing losses impair reinvestment capacity and elevate execution risk for longer-term growth plans.
Negative Return on Equity
A negative ROE indicates the company is destroying shareholder value rather than generating returns on invested equity. Persisting at this level undermines investor confidence, complicates non-dilutive financing access, and pressures management to materially improve profitability or capital efficiency.

Cuorips Inc. (4894) vs. iShares MSCI Japan ETF (EWJ)

Cuorips Inc. Business Overview & Revenue Model

Company DescriptionCuorips Inc. engages in the research, development, manufacture, commercialization, and sale of iPS cell-derived cardiomyocyte sheets. The company offers cellular and tissue-based, and cell processing products. It also provides contract development and manufacturing, and consulting services. The company was formerly known as Cuore Inc. and changed its name to Cuorips Inc. in June 2017. Cuorips Inc. was incorporated in 2017 and is headquartered in Tokyo, Japan.
How the Company Makes MoneyCuorips Inc. generates revenue through the development and commercialization of regenerative medicine products targeting cardiac diseases. The company makes money by licensing its proprietary technologies and therapies to pharmaceutical and biotechnology companies. Additionally, Cuorips Inc. may receive funding through collaborative research agreements and partnerships with healthcare institutions and academic entities. Revenue streams could also include milestone payments and royalties from successfully developed and marketed therapies. The company's earnings are significantly influenced by its ability to advance its pipeline products through clinical trials and secure regulatory approvals.

Cuorips Inc. Financial Statement Overview

Summary
Revenue growth is strong (+~404% to ~¥175m) with a solid gross margin (~52%) and a debt-free balance sheet with meaningful equity (~¥5.5b). However, operating and net losses remain very large (EBIT ~-¥590m; net ~-¥644m) and cash burn is heavy (operating CF ~-¥813m; FCF ~-¥893m), keeping financial risk elevated until breakeven visibility improves.
Income Statement
22
Negative
Revenue has scaled sharply in the latest year (2025 annual revenue up ~404% to ~¥175m), and gross margin remains solid (~52%). However, profitability is very weak: operating losses remain extremely large (EBIT about -¥590m) and net losses deepened to about -¥644m, leaving net margin highly negative. Overall, the company shows early commercial traction but still lacks a clear path to operating breakeven based on the current cost structure.
Balance Sheet
74
Positive
The balance sheet is conservatively levered with zero reported debt and meaningful equity (~¥5.5b) supporting a largely equity-funded profile. That said, returns remain negative (return on equity around -11.7% in 2025), indicating ongoing value dilution risk if losses persist. Overall financial flexibility looks good, but sustained losses continue to pressure long-term capital efficiency.
Cash Flow
25
Negative
Cash generation is weak, with operating cash flow negative and worsening in 2025 (about -¥813m), and free cash flow also deeply negative (about -¥893m), implying a high cash burn profile. Free cash flow is consistently negative relative to net income (free cash flow to net income > 1), suggesting losses are translating into real cash outflows rather than being primarily non-cash. The key strength is consistency of reporting and a lack of debt-related cash burden, but the burn rate remains the central risk.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue260.31M175.21M23.10M38.28M13.91M220.00K
Gross Profit119.12M91.56M9.63M21.01M10.65M138.00K
EBITDA-570.19M-565.32M-518.00M-371.78M-280.40M-221.17M
Net Income-652.25M-644.34M-632.18M-452.08M-375.34M-307.83M
Balance Sheet
Total Assets5.75B5.74B6.18B3.59B4.04B4.36B
Cash, Cash Equivalents and Short-Term Investments4.85B4.79B5.58B2.94B3.34B3.54B
Total Debt0.000.000.000.000.000.00
Total Liabilities324.59M211.91M200.96M133.79M149.36M141.95M
Stockholders Equity5.42B5.53B5.98B3.45B3.90B4.22B
Cash Flow
Free Cash Flow0.00-892.81M-487.01M-412.18M-249.45M-950.97M
Operating Cash Flow0.00-812.62M-451.06M-401.61M-220.76M-282.80M
Investing Cash Flow0.00-119.99M-35.00M-8.97M-28.44M-670.21M
Financing Cash Flow0.00145.11M3.13B10.69M48.54M3.77B

Cuorips Inc. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price6230.00
Price Trends
50DMA
6697.60
Positive
100DMA
6774.90
Positive
200DMA
6637.10
Positive
Market Momentum
MACD
389.27
Positive
RSI
58.76
Neutral
STOCH
51.41
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4894, the sentiment is Positive. The current price of 6230 is below the 20-day moving average (MA) of 7637.00, below the 50-day MA of 6697.60, and below the 200-day MA of 6637.10, indicating a bullish trend. The MACD of 389.27 indicates Positive momentum. The RSI at 58.76 is Neutral, neither overbought nor oversold. The STOCH value of 51.41 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:4894.

Cuorips Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
¥21.93B-47.52-5.65%-469.19%
55
Neutral
¥65.25B-97.231772.85%16.16%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
¥17.17B-13.9214.03%
46
Neutral
¥19.61B542.68-32.68%
45
Neutral
¥44.21B-9.72-82.33%47.73%
43
Neutral
¥18.18B-9.5011.34%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4894
Cuorips Inc.
7,910.00
3,545.00
81.21%
JP:4575
CanBas Co., Ltd.
871.00
8.00
0.93%
JP:4593
Healios KK
382.00
110.00
40.44%
JP:4599
StemRIM Inc.
290.00
-23.00
-7.35%
JP:4889
Renascience Inc.
1,480.00
55.00
3.86%
JP:7774
Japan Tissue Engineering Co., Ltd.
540.00
71.00
15.14%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 09, 2026