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OncoTherapy Science, Inc. (JP:4564)
:4564
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OncoTherapy Science (4564) AI Stock Analysis

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JP:4564

OncoTherapy Science

(Frankfurt:4564)

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Neutral 43 (OpenAI - 4o)
Rating:43Neutral
Price Target:
¥26.00
▲(0.00% Upside)
The overall stock score of 43 reflects significant financial challenges, with persistent losses and cash flow issues being the most impactful factors. Technical analysis indicates a lack of strong momentum, and valuation metrics highlight ongoing profitability issues. The absence of earnings call data and corporate events limits further insights.

OncoTherapy Science (4564) vs. iShares MSCI Japan ETF (EWJ)

OncoTherapy Science Business Overview & Revenue Model

Company DescriptionOncoTherapy Science, Inc. researches and develops anti-cancer medicines and therapies in Japan. Its clinical development product pipeline includes small-molecule drugs, such as OTS167, a maternal embryonic leucine zipper kinase inhibitor that is in Phase I/II clinical trials for the treatment of acute myeloid leukemia, as well as in Phase I clinical trials for the treatment of breast cancer; and OTS964, a T-LAK cell-originated protein kinase inhibitor for the treatment of various cancer diseases. The company's clinical development product pipeline also comprise cancer- specific peptide vaccines, including S-588410, which is in Phase III clinical trials for the treatment esophageal cancer, as well as in Phase II clinical trials for the treatment of bladder cancer; S-488210 that is in Phase I/II clinical trials for the treatment of head and neck cancer; and S-588210, which is in Phase I clinical trials for the treatment of solid tumor. In addition, it is developing antibody drugs consisting of OTSA101, which is in Phase I clinical trials for synovial sarcoma; and KHK6640, an anti-amyloid beta peptide antibody that is Phase I clinical trials for Alzheimer's disease. Further, the company provides contract analysis services. OncoTherapy Science, Inc. was founded in 2001 and is headquartered in Kawasaki, Japan.
How the Company Makes MoneyOncoTherapy Science generates revenue through various streams, including licensing agreements, research and development collaborations, and potential product sales. The company often partners with pharmaceutical and biotechnology firms to co-develop and commercialize its therapeutic candidates, receiving milestone payments and royalties. Additionally, OncoTherapy Science may secure government and private grants to fund its research initiatives, further supporting its financial sustainability.

OncoTherapy Science Financial Statement Overview

Summary
OncoTherapy Science faces significant financial challenges, with persistent losses and cash flow issues. The income statement reflects a struggling financial performance with negative margins, while the balance sheet shows moderate debt levels but declining equity. Cash flow issues are severe, with negative free and operating cash flows, indicating financial instability.
Income Statement
35
Negative
The company has experienced significant challenges in profitability, with consistently negative net and gross profit margins. Revenue growth is erratic, with fluctuations in revenue suggesting instability. EBIT and EBITDA margins have been consistently negative, indicating operational inefficiencies. Overall, the income statement reflects a struggling financial performance, typical in high-risk biotech ventures.
Balance Sheet
45
Neutral
The balance sheet shows a relatively high equity ratio, supported by substantial stockholders' equity compared to total assets. However, the company carries significant liabilities, resulting in a moderate debt-to-equity ratio. The consistent decline in total assets and stockholders' equity over the years indicates potential risk. The company's ability to manage liabilities is crucial, given its negative equity growth trend.
Cash Flow
30
Negative
The cash flow statements reveal persistent negative free cash flow and operating cash flow, which are concerning for future liquidity. The company has relied heavily on financing activities to sustain operations, indicating potential challenges in sustaining cash flows from core operations. There is a lack of positive cash flow generation, which poses a risk to financial stability.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue749.75M750.05M610.12M1.13B1.15B332.48M
Gross Profit-12.76M-12.76M-177.72M41.69M113.91M19.54M
EBITDA-539.99M-811.92M-1.29B-1.09B-2.04B-1.59B
Net Income-815.05M-815.28M-1.29B-1.12B-2.57B-1.56B
Balance Sheet
Total Assets1.16B1.16B867.27M1.51B2.69B3.37B
Cash, Cash Equivalents and Short-Term Investments833.88M833.88M527.66M1.12B1.84B2.90B
Total Debt51.07M51.07M106.85M0.000.000.00
Total Liabilities426.09M426.09M513.61M656.27M704.97M291.28M
Stockholders Equity729.11M729.11M353.67M855.17M1.98B3.08B
Cash Flow
Free Cash Flow0.00-815.30M-1.23B-800.29M-2.53B-1.81B
Operating Cash Flow0.00-815.02M-1.23B-794.90M-2.07B-1.76B
Investing Cash Flow0.00-279.00K-33.35M-20.32M-467.93M-52.23M
Financing Cash Flow0.001.12B671.37M95.95M1.48B0.00

OncoTherapy Science Technical Analysis

Technical Analysis Sentiment
Negative
Last Price26.00
Price Trends
50DMA
27.88
Negative
100DMA
26.12
Negative
200DMA
26.20
Negative
Market Momentum
MACD
-0.30
Positive
RSI
44.21
Neutral
STOCH
38.89
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4564, the sentiment is Negative. The current price of 26 is below the 20-day moving average (MA) of 27.50, below the 50-day MA of 27.88, and below the 200-day MA of 26.20, indicating a bearish trend. The MACD of -0.30 indicates Positive momentum. The RSI at 44.21 is Neutral, neither overbought nor oversold. The STOCH value of 38.89 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4564.

OncoTherapy Science Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
48
Neutral
¥9.12B-8.5530.92%26.00%
46
Neutral
¥64.40B-9.12-476.97%-78.54%10.23%
43
Neutral
€8.80B-96.20%51.20%44.10%
41
Neutral
¥15.95B-6.68-61.22%-9.04%2.12%
38
Underperform
¥4.26B-2.50965.85%-42.78%
28
Underperform
¥6.18B-3.1320.41%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4564
OncoTherapy Science
26.00
-12.00
-31.58%
JP:4583
Chiome Bioscience Inc.
134.00
12.00
9.84%
JP:4588
Oncolys BioPharma, Inc.
622.00
56.00
9.89%
JP:4593
Healios KK
558.00
327.00
141.56%
JP:4598
Delta-Fly Pharma, Inc.
536.00
-50.00
-8.53%
JP:4881
FunPep Company Limited
105.00
-32.00
-23.36%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 26, 2025