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Chiome Bioscience Inc. (JP:4583)
:4583
Japanese Market
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Chiome Bioscience Inc. (4583) Price & Analysis

2 Followers

4583 Stock Chart & Stats

¥106.00
-¥13.00(-4.94%)
At close: 4:00 PM EST
¥106.00
-¥13.00(-4.94%)

Bulls Say, Bears Say

Bulls Say
Proprietary Tech And Partner CollaborationsChiome’s business model centers on proprietary antibody and ADC discovery and advancement, and its repeated collaborations with larger pharmaceutical partners provide durable benefits: access to development resources, risk-sharing, external validation and pathways to licensing or co-development that support program progression over the next several quarters.
Relatively Strong Gross MarginsReported gross margins around 55–60% indicate favorable product-level economics for its biologics work. While total profitability is negative today, resilient gross margins imply scalable unit economics for successful candidates and improve the likelihood that revenue growth or licensing deals can translate to margin expansion as programs advance.
Modest Leverage And Low DebtLow debt-to-equity and small absolute debt provide financial flexibility: limited interest burden and lower solvency pressure reduce near-term distress risk, enabling the company to prioritize R&D spend or seek strategic partnerships and external capital without immediate refinancing stress over the medium term.
Bears Say
Persistent Negative Operating And Free Cash FlowOperating and free cash flows have been consistently negative and sizable, closely tracking accounting losses. Persistent cash burn raises funding risk, likely requiring dilution, licensing or strategic alliances to sustain R&D and clinical programs, constraining independent program advancement absent material external funding.
Deep And Volatile UnprofitabilityNet margins are deeply negative and losses substantially exceed revenues, signaling structural unprofitability. This persistent deficit risks equity erosion, limits reinvestment capacity, and means the company relies on external funding or transformative clinical/partner milestones to reach sustainable profit generation over the medium term.
Revenue Volatility And Recent DeclineRevenue volatility and a ~23% decline in 2025 after prior growth indicate unstable commercial or partner-derived receipts. Such inconsistency complicates planning, undermines predictable funding from operations, and increases dependence on irregular milestone payments or new agreements to maintain program funding and operations over coming quarters.

Chiome Bioscience Inc. News

4583 FAQ

What was Chiome Bioscience Inc.’s price range in the past 12 months?
Chiome Bioscience Inc. lowest stock price was ¥90.00 and its highest was ¥168.00 in the past 12 months.
    What is Chiome Bioscience Inc.’s market cap?
    Chiome Bioscience Inc.’s market cap is ¥6.87B.
      When is Chiome Bioscience Inc.’s upcoming earnings report date?
      The company’s upcoming earnings report date is not yet available.
      How were Chiome Bioscience Inc.’s earnings last quarter?
      Currently, no data Available
      Is Chiome Bioscience Inc. overvalued?
      According to Wall Street analysts Chiome Bioscience Inc.’s price is currently Overvalued. Get more investment ideas with TipRanks Premium
        Does Chiome Bioscience Inc. pay dividends?
        Chiome Bioscience Inc. does not currently pay dividends.
        What is Chiome Bioscience Inc.’s EPS estimate?
        Chiome Bioscience Inc.’s EPS estimate for its next earnings report is not yet available.
        How many shares outstanding does Chiome Bioscience Inc. have?
        Chiome Bioscience Inc. has 74,659,200 shares outstanding.
          What happened to Chiome Bioscience Inc.’s price movement after its last earnings report?
          Currently, no data Available
          Which hedge fund is a major shareholder of Chiome Bioscience Inc.?
          Currently, no hedge funds are holding shares in JP:4583
          What is the TipRanks Smart Score and how is it calculated?
          Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology

            Company Description

            Chiome Bioscience Inc.

            Chiome Bioscience Inc. engages in the research and development of drug discovery technology platforms worldwide. The company operates through two segments, Drug Discovery Business and Drug Discovery Support Business. It offers ADLib System, a monoclonal antibody generating system for drug discovery and development; and Human ADLib System, a chicken antibody gene converted to humanized antibodies. The company also provides protein expression and purification services; stable cell line generation services for recombinant protein and antibody production; and antibody generation services using the ADLib system or B cell cloning techniques. Its product pipeline comprises ADCT-701, an anti-dlk1 antibody for treating liver cancer which is under phase 1 trial; CBA-1205, an afucosylated anti-dlk1 antibody for liver cancer, lung cancer, and neuroblastoma which is under phase 1 trial; and CBA-1535, an anti 5T4/WAIF1 antibody for malignant mesothelioma, small cell lung cancer, non-small cell lung cancer, and breast cancer (TNBC) which is under phase 1 trial. The company's product pipeline under preclinical study includes LIV-2008/2008b, an anti-TROP-2 antibody for the treatment of TNBC, lung cancer, and colorectal cancer; BMAA, an anti-semphorin3a antibody for treating central, immune/ inflammatory diseases, neurological disorder, and ophthalmic diseases; PCDC, an anti- CDCP1 antibody for lung, colorectal, pancreatic, breast, and ovarian tumors; PTRY, an antibody 5T4/CD3/PD-L1 for treating malignant mesothelioma, small cell lung cancer, non-small cell lung cancer, triple negative breast cancer; and PFKR, anti-CX3CR1 antibody for secondary progressive multiple sclerosis. It serves universities, research institutions, and pharmaceutical companies. Chiome Bioscience Inc. was incorporated in 2005 and is headquartered in Tokyo, Japan.

            Chiome Bioscience Inc. (4583) Earnings & Revenues

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