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Chiome Bioscience Inc. (JP:4583)
:4583
Japanese Market
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Chiome Bioscience Inc. (4583) Price & Analysis

2 Followers

4583 Stock Chart & Stats

¥106.00
-¥13.00(-4.94%)
At close: 4:00 PM EST
¥106.00
-¥13.00(-4.94%)

Bulls Say, Bears Say

Bulls Say
Proprietary Platform And Pharma CollaborationsChiome's proprietary antibody/ADC platform and routine collaborations with larger pharma provide durable R&D leverage and external validation. Partnerships can supply non‑dilutive funding, regulatory and commercialization expertise, and increase the odds of licensing or late‑stage success over months to years.
Consistently Healthy Gross MarginsSustained gross margins near 55–60% point to IP‑driven revenue economics that can scale more efficiently than low‑margin businesses. If programs convert to partnered revenue or product sales, these margins support improved operating leverage and a stronger ability to retain proceeds for further R&D investment.
Modest Financial LeverageLow debt ratios provide durable financial flexibility for a development‑stage biotech. Modest leverage reduces immediate insolvency risk, making it easier to endure R&D cycles, secure partnership deals, or raise capital without the pressure of heavy interest burdens in the next several quarters.
Bears Say
Persistent Negative Cash FlowConsistently negative operating and free cash flow means accounting losses convert into real cash burn, depleting runway. Persistent outflows force reliance on financing or partners, increasing dilution and execution risk if clinical or licensing milestones do not materialize over the coming 2–6 months.
Deep Unprofitability And Recent Revenue DeclineVery large net losses and a ~23% revenue decline in 2025 signal an uneven path to scale. Continued wide negative margins reduce internal funding capacity and indicate commercialization or pipeline monetization challenges, making sustained improvement dependent on costly development successes or external funding.
Equity Volatility Raises Funding RiskVolatile equity and negative ROE reflect balance‑sheet erosion in weaker periods. Even with low debt, declining equity typically leads to dilutive financing or urgent licensing deals, constraining strategic choices and risking shareholder value if profitability isn't restored within upcoming financing cycles.

Chiome Bioscience Inc. News

4583 FAQ

What was Chiome Bioscience Inc.’s price range in the past 12 months?
Chiome Bioscience Inc. lowest stock price was ¥101.00 and its highest was ¥168.00 in the past 12 months.
    What is Chiome Bioscience Inc.’s market cap?
    Chiome Bioscience Inc.’s market cap is ¥7.34B.
      When is Chiome Bioscience Inc.’s upcoming earnings report date?
      The company’s upcoming earnings report date is not yet available.
      How were Chiome Bioscience Inc.’s earnings last quarter?
      Currently, no data Available
      Is Chiome Bioscience Inc. overvalued?
      According to Wall Street analysts Chiome Bioscience Inc.’s price is currently Overvalued. Get more investment ideas with TipRanks Premium
        Does Chiome Bioscience Inc. pay dividends?
        Chiome Bioscience Inc. does not currently pay dividends.
        What is Chiome Bioscience Inc.’s EPS estimate?
        Chiome Bioscience Inc.’s EPS estimate for its next earnings report is not yet available.
        How many shares outstanding does Chiome Bioscience Inc. have?
        Chiome Bioscience Inc. has 72,651,300 shares outstanding.
          What happened to Chiome Bioscience Inc.’s price movement after its last earnings report?
          Currently, no data Available
          Which hedge fund is a major shareholder of Chiome Bioscience Inc.?
          Currently, no hedge funds are holding shares in JP:4583
          What is the TipRanks Smart Score and how is it calculated?
          Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology

            Company Description

            Chiome Bioscience Inc.

            Chiome Bioscience Inc. engages in the research and development of drug discovery technology platforms worldwide. The company operates through two segments, Drug Discovery Business and Drug Discovery Support Business. It offers ADLib System, a monoclonal antibody generating system for drug discovery and development; and Human ADLib System, a chicken antibody gene converted to humanized antibodies. The company also provides protein expression and purification services; stable cell line generation services for recombinant protein and antibody production; and antibody generation services using the ADLib system or B cell cloning techniques. Its product pipeline comprises ADCT-701, an anti-dlk1 antibody for treating liver cancer which is under phase 1 trial; CBA-1205, an afucosylated anti-dlk1 antibody for liver cancer, lung cancer, and neuroblastoma which is under phase 1 trial; and CBA-1535, an anti 5T4/WAIF1 antibody for malignant mesothelioma, small cell lung cancer, non-small cell lung cancer, and breast cancer (TNBC) which is under phase 1 trial. The company's product pipeline under preclinical study includes LIV-2008/2008b, an anti-TROP-2 antibody for the treatment of TNBC, lung cancer, and colorectal cancer; BMAA, an anti-semphorin3a antibody for treating central, immune/ inflammatory diseases, neurological disorder, and ophthalmic diseases; PCDC, an anti- CDCP1 antibody for lung, colorectal, pancreatic, breast, and ovarian tumors; PTRY, an antibody 5T4/CD3/PD-L1 for treating malignant mesothelioma, small cell lung cancer, non-small cell lung cancer, triple negative breast cancer; and PFKR, anti-CX3CR1 antibody for secondary progressive multiple sclerosis. It serves universities, research institutions, and pharmaceutical companies. Chiome Bioscience Inc. was incorporated in 2005 and is headquartered in Tokyo, Japan.

            Chiome Bioscience Inc. (4583) Earnings & Revenues

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