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Chiome Bioscience Inc. (JP:4583)
:4583
Japanese Market
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Chiome Bioscience Inc. (4583) AI Stock Analysis

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JP:4583

Chiome Bioscience Inc.

(4583)

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Underperform 40 (OpenAI - 5.2)
Rating:40Underperform
Price Target:
¥63.00
▼(-40.57% Downside)
Action:Downgraded
Date:06/03/26
The score is driven primarily by weak financial performance (persistent losses and ongoing cash burn) and bearish technicals (price below major moving averages with negative momentum). Valuation provides only limited support because the company is loss-making and no dividend yield is available.
Positive Factors
Proprietary ADC platform & partnerships
Chiome's proprietary antibody and ADC technology and explicit collaboration model create durable product-development optionality. Platform IP plus partner relationships can de-risk clinical costs, accelerate development, and provide downstream commercialization channels over the coming months to years.
Negative Factors
Persistent negative operating cash flow
Sustained negative operating and free cash flow shows that losses are translating into real cash burn, increasing financing need. Over a 2–6 month horizon this raises dilution or funding risk, constraining trial progression and strategic initiatives absent partner funding.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary ADC platform & partnerships
Chiome's proprietary antibody and ADC technology and explicit collaboration model create durable product-development optionality. Platform IP plus partner relationships can de-risk clinical costs, accelerate development, and provide downstream commercialization channels over the coming months to years.
Read all positive factors

Chiome Bioscience Inc. (4583) vs. iShares MSCI Japan ETF (EWJ)

Chiome Bioscience Inc. Business Overview & Revenue Model

Company Description
Chiome Bioscience Inc. engages in the research and development of drug discovery technology platforms worldwide. It operates in two segments, Drug Discovery Business and Drug Discovery Support Business. The company offers ADLib System, a technolog...
How the Company Makes Money
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Chiome Bioscience Inc. Financial Statement Overview

Summary
Financial profile is weak: income statement and cash flow scores are very low due to persistent large losses, negative margins, and ongoing cash burn. Balance sheet leverage is modest, but equity volatility and negative returns reflect continued strain.
Income Statement
18
Very Negative
Balance Sheet
54
Neutral
Cash Flow
16
Very Negative
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue768.88M593.29M780.81M682.46M630.82M712.93M
Gross Profit436.96M355.58M432.02M397.72M347.78M420.59M
EBITDA-989.98M-972.64M-1.01B-1.21B-1.24B-1.46B
Net Income-997.11M-982.78M-1.02B-1.22B-1.24B-1.48B
Balance Sheet
Total Assets1.96B1.73B2.47B1.75B2.22B2.34B
Cash, Cash Equivalents and Short-Term Investments1.47B1.21B2.06B1.33B1.73B1.79B
Total Debt260.50M261.70M281.50M291.00M184.00M183.00M
Total Liabilities443.39M605.44M548.55M593.73M424.72M446.39M
Stockholders Equity1.52B1.12B1.92B1.16B1.79B1.89B
Cash Flow
Free Cash Flow0.00-976.07M-1.00B0.00-1.19B0.00
Operating Cash Flow0.00-935.99M-1.00B-1.07B-1.19B-1.13B
Investing Cash Flow0.00-55.46M0.00173.00K0.00-35.38M
Financing Cash Flow0.00133.20M1.74B667.30M1.13B271.35M

Chiome Bioscience Inc. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price106.00
Price Trends
50DMA
84.02
Negative
100DMA
96.19
Negative
200DMA
109.45
Negative
Market Momentum
MACD
-2.71
Negative
RSI
53.44
Neutral
STOCH
91.11
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4583, the sentiment is Negative. The current price of 106 is above the 20-day moving average (MA) of 70.35, above the 50-day MA of 84.02, and below the 200-day MA of 109.45, indicating a neutral trend. The MACD of -2.71 indicates Negative momentum. The RSI at 53.44 is Neutral, neither overbought nor oversold. The STOCH value of 91.11 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4583.

Chiome Bioscience Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
¥9.09B27.633.66%32.11%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
¥11.52B159.1211.45%
47
Neutral
¥88.76B-8.69-19.31%10.88%-327.56%
47
Neutral
¥79.65B-43.000.80%32.87%
41
Neutral
¥136.25B-37.97-10.16%-59.19%-124.16%
40
Underperform
¥6.00B-5.49-23.82%14.80%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4583
Chiome Bioscience Inc.
76.00
-65.00
-46.10%
JP:4587
Peptidream
1,049.50
-519.50
-33.11%
JP:4565
Sosei Group
960.00
103.00
12.02%
JP:4570
Immuno-Biological Laboratories Co., Ltd.
976.00
485.11
98.82%
JP:4579
RaQualia Pharma Inc.
471.00
-55.00
-10.46%
JP:4588
Oncolys BioPharma, Inc.
2,721.00
2,123.00
355.02%

Chiome Bioscience Inc. Corporate Events

Chiome Bioscience Outlines Q1 FY2026 Results and Pipeline Focus
May 14, 2026
Chiome Bioscience Inc. reported supplementary information for its financial results for the first quarter of fiscal year ending December 2026. The materials outline both financial performance and operational highlights, indicating continued focus ...
Chiome Bioscience Narrows Quarterly Loss as Equity Ratio Improves, Keeps Cautious Outlook
May 14, 2026
Chiome Bioscience reported non-consolidated net sales of ¥147 million for the first quarter ended March 31, 2026, a 6.1% year-on-year increase, while trimming its net loss to ¥233 million as operating and ordinary losses narrowed. Total ...
Chiome Bioscience Corrects FY2025 Results as Losses and Cash Burn Persist
Mar 27, 2026
Chiome Bioscience has issued an updated version of its non-consolidated financial results for the fiscal year ended December 31, 2025, correcting specific items related to share count, cash flow statements, segment information, and per-share data....
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 03, 2026