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GNI Group Ltd. (JP:2160)
:2160

GNI Group (2160) AI Stock Analysis

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JP:2160

GNI Group

(2160)

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Neutral 45 (OpenAI - 4o)
Rating:45Neutral
Price Target:
¥2,311.00
▼(-6.81% Downside)
The overall stock score reflects significant financial and valuation challenges. The company's negative profitability and cash flow issues are major concerns, compounded by a bearish technical outlook. The lack of earnings call and corporate events data limits further insights.
Positive Factors
Revenue Growth
Positive revenue growth indicates expanding market presence and demand for GNI Group's biopharmaceutical products, supporting long-term business sustainability.
Low Debt Levels
A low debt-to-equity ratio suggests conservative financial management, providing GNI Group with flexibility to invest in growth opportunities without significant leverage risks.
Long-term Contracts
Long-term contracts with major pharmaceutical companies ensure a steady revenue stream, enhancing financial stability and enabling strategic planning for future growth.
Negative Factors
Negative Profitability
Negative profitability indicates operational inefficiencies, which can hinder GNI Group's ability to reinvest in R&D and maintain competitive positioning.
Negative Cash Flows
Negative cash flows suggest liquidity issues, potentially limiting GNI Group's capacity to fund operations and invest in growth initiatives without external financing.
Negative Return on Equity
A negative return on equity reflects inefficiencies in generating returns from shareholders' equity, which may deter investment and affect long-term growth prospects.

GNI Group (2160) vs. iShares MSCI Japan ETF (EWJ)

GNI Group Business Overview & Revenue Model

Company DescriptionGNI Group Ltd. engages in the research, development, manufacture, and sale of pharmaceutical drugs and traditional Chinese medicines in Japan and internationally. It provides Etuary for the treatment of idiopathic pulmonary fibrosis. The company is also developing Etuary, which is in Phase III clinical trial for the treatment of connective tissue associated interstitial lung disease; and in clinical trial phase II and pre-phase III clinical trial pilot study for the treatment of radiation pneumonitis, as well as for the treatment of diabetic nephropathy. In addition, it is involved in developing F351, which is in Phase II clinical trial for the treatment of liver fibrosis; and F573 that is in pre-clinical phase for the treatment of acute on chronic liver failure, as well as Tamibarotene for the treatment of acute promyelocytic leukemia. GNI Group Ltd. was incorporated in 2001 and is headquartered in Tokyo, Japan.
How the Company Makes MoneyGNI Group generates revenue primarily through the sale of its biopharmaceutical products and services, including the production of active pharmaceutical ingredients (APIs) for various therapeutic areas. The company's revenue model is bolstered by long-term contracts and collaborations with major pharmaceutical companies, which provide a steady stream of income. Additionally, GNI Group benefits from research and development partnerships that enhance its product offerings and market reach. The company may also earn revenue from licensing agreements and royalties associated with its proprietary technologies and innovations in the biotech field.

GNI Group Financial Statement Overview

Summary
The company faces profitability and cash flow challenges, with a negative net profit margin and deteriorating cash generation, despite a strong gross profit margin and manageable leverage.
Income Statement
45
Neutral
The income statement shows a mixed performance. The TTM data indicates a gross profit margin of 75.8%, which is strong, but the net profit margin is negative at -4.38%, reflecting recent profitability challenges. Revenue growth is positive at 4.99% TTM, but EBIT and EBITDA margins have turned negative, indicating operational inefficiencies.
Balance Sheet
60
Neutral
The balance sheet is relatively stable with a low debt-to-equity ratio of 0.19 TTM, suggesting manageable leverage. However, the return on equity is negative at -2.87% TTM, indicating inefficiencies in generating returns from equity. The equity ratio is not provided, but the overall leverage appears controlled.
Cash Flow
40
Negative
Cash flow analysis reveals challenges, with negative operating and free cash flows TTM. The free cash flow growth rate is -19.72%, indicating deteriorating cash generation. The operating cash flow to net income ratio is negative, highlighting cash flow issues relative to earnings.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue25.78B23.61B26.01B17.42B12.69B9.77B
Gross Profit18.74B18.04B22.43B14.74B11.09B8.23B
EBITDA327.64M2.39B14.49B2.16B2.14B2.19B
Net Income-823.42M977.66M8.09B388.82M1.07B1.26B
Balance Sheet
Total Assets82.60B71.94B62.39B33.91B30.30B23.22B
Cash, Cash Equivalents and Short-Term Investments22.78B12.93B23.15B11.25B14.36B10.34B
Total Debt4.97B7.21B3.70B537.36M1.13B1.75B
Total Liabilities30.06B32.23B26.34B14.10B11.03B10.45B
Stockholders Equity50.05B36.45B33.79B20.97B18.86B11.00B
Cash Flow
Free Cash Flow-2.16B-3.69B4.47B-1.55B-142.13M1.02B
Operating Cash Flow-1.81B-3.16B6.55B393.32M552.27M1.38B
Investing Cash Flow-352.08M-10.36B-6.84B-4.12B-260.64M570.21M
Financing Cash Flow10.20B694.16M10.69B-646.33M2.85B801.12M

GNI Group Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2480.00
Price Trends
50DMA
2438.02
Positive
100DMA
2573.82
Negative
200DMA
2717.43
Negative
Market Momentum
MACD
-19.52
Negative
RSI
53.50
Neutral
STOCH
68.46
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:2160, the sentiment is Positive. The current price of 2480 is above the 20-day moving average (MA) of 2428.20, above the 50-day MA of 2438.02, and below the 200-day MA of 2717.43, indicating a neutral trend. The MACD of -19.52 indicates Negative momentum. The RSI at 53.50 is Neutral, neither overbought nor oversold. The STOCH value of 68.46 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:2160.

GNI Group Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
¥221.22B-38.63-10.16%-62.47%-134.06%
49
Neutral
¥94.65B-14.852.16%-0.16%-802.20%
48
Neutral
¥128.51B-34.50-636.97%-12.69%
46
Neutral
¥78.19B-12.51-9.05%-1.96%-64.18%
45
Neutral
¥137.08B-168.04-1.81%13.78%-110.02%
37
Underperform
¥33.25B-7.94-82.33%47.73%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:2160
GNI Group
2,480.00
-655.00
-20.89%
JP:4587
Peptidream
1,737.50
-858.00
-33.06%
JP:4592
SanBio Co
1,665.00
815.00
95.88%
JP:4565
Sosei Group
853.00
-208.00
-19.60%
JP:4593
Healios KK
312.00
130.00
71.43%
JP:4974
Takara Bio Inc.
787.00
-205.16
-20.68%

GNI Group Corporate Events

GNI Group Reports Q3 FY2025 Financial Results: Revenue Up, Profitability Down
Nov 14, 2025

GNI Group Ltd. reported its consolidated financial results for the third quarter of fiscal year 2025, showing a revenue increase of 12.6% year-on-year to 19,357 million yen. However, the company faced operating and pre-tax losses, with a notable decline in profit attributable to owners of the parent. Despite the revenue growth, the financial results indicate challenges in profitability, which may impact the company’s market positioning and stakeholder confidence.

GNI Group’s Subsidiary Completes Enrollment for Key Clinical Trial
Oct 16, 2025

GNI Group Ltd. announced that its subsidiary, Gyre Therapeutics, has completed subject enrollment for a Phase 3 clinical trial of Pirfenidone Capsule, aimed at treating pneumoconiosis. This trial, conducted across 18 centers in China, evaluates the drug’s efficacy and safety over 52 weeks. The completion of enrollment marks a significant step in the development of treatments for this chronic lung disease, although the financial impact on GNI Group’s current fiscal year is expected to be minimal.

GNI Group Advances Non-Opioid Pain Therapy with Phase 1 Trial Completion
Sep 18, 2025

GNI Group Ltd. announced the completion of subject enrollment for the Phase 1 clinical trial of CG001419, a novel non-opioid pain product candidate developed by its subsidiary Cullgen. This trial marks a significant step in offering a new class of pain signal inhibitors that could provide safer and more effective treatment options for acute and chronic pain, with plans to advance to Phase 2 trials by early next year. The financial impact on the company’s current fiscal year is expected to be minimal.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 11, 2025