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GNI Group Ltd. (JP:2160)
:2160
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GNI Group (2160) AI Stock Analysis

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JP:2160

GNI Group

(2160)

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Neutral 44 (OpenAI - 4o)
Rating:44Neutral
Price Target:
¥2,291.00
▼(-5.95% Downside)
The overall stock score is primarily impacted by financial performance challenges, including negative profitability and cash flow issues. Technical analysis further indicates bearish momentum, while valuation metrics highlight significant concerns with a negative P/E ratio and no dividend yield.

GNI Group (2160) vs. iShares MSCI Japan ETF (EWJ)

GNI Group Business Overview & Revenue Model

Company DescriptionGNI Group Ltd. engages in the research, development, manufacture, and sale of pharmaceutical drugs and traditional Chinese medicines in Japan and internationally. It provides Etuary for the treatment of idiopathic pulmonary fibrosis. The company is also developing Etuary, which is in Phase III clinical trial for the treatment of connective tissue associated interstitial lung disease; and in clinical trial phase II and pre-phase III clinical trial pilot study for the treatment of radiation pneumonitis, as well as for the treatment of diabetic nephropathy. In addition, it is involved in developing F351, which is in Phase II clinical trial for the treatment of liver fibrosis; and F573 that is in pre-clinical phase for the treatment of acute on chronic liver failure, as well as Tamibarotene for the treatment of acute promyelocytic leukemia. GNI Group Ltd. was incorporated in 2001 and is headquartered in Tokyo, Japan.
How the Company Makes MoneyGNI Group generates revenue primarily through the sale of its biopharmaceutical products and services, including the production of active pharmaceutical ingredients (APIs) for various therapeutic areas. The company's revenue model is bolstered by long-term contracts and collaborations with major pharmaceutical companies, which provide a steady stream of income. Additionally, GNI Group benefits from research and development partnerships that enhance its product offerings and market reach. The company may also earn revenue from licensing agreements and royalties associated with its proprietary technologies and innovations in the biotech field.

GNI Group Financial Statement Overview

Summary
GNI Group shows a mixed financial picture with a strong balance sheet offset by weak income and cash flow statements. While the company maintains a stable equity position, declining revenues and negative earnings signal operational issues.
Income Statement
45
Neutral
The company experienced a significant decline in performance with negative EBIT and net income in the TTM period. Gross profit margin remains strong, but revenue has decreased, indicating potential challenges in maintaining growth.
Balance Sheet
60
Neutral
The balance sheet shows a solid equity base with an equity ratio of approximately 50%. The debt-to-equity ratio remains low, demonstrating a conservative leverage approach. However, the decrease in stockholders' equity may be concerning.
Cash Flow
40
Negative
Negative operating and free cash flows highlight liquidity challenges. The cash flow to net income ratio is unfavorable, indicating financial struggles in maintaining cash reserves.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue24.13B23.61B26.01B17.42B12.69B9.77B
Gross Profit17.30B18.04B22.43B14.74B11.09B8.23B
EBITDA105.29M2.39B14.49B2.16B2.14B2.19B
Net Income-267.85M977.66M8.09B388.82M1.07B1.26B
Balance Sheet
Total Assets67.72B71.94B62.39B33.91B30.30B23.22B
Cash, Cash Equivalents and Short-Term Investments10.52B12.93B23.15B11.25B14.36B10.34B
Total Debt4.86B7.21B3.70B537.36M1.13B1.75B
Total Liabilities29.41B32.23B26.34B14.10B11.03B10.45B
Stockholders Equity35.27B36.45B33.79B20.97B18.86B11.00B
Cash Flow
Free Cash Flow-3.03B-3.69B4.47B-1.55B-142.13M1.02B
Operating Cash Flow-2.63B-3.16B6.55B393.32M552.27M1.38B
Investing Cash Flow-918.42M-10.36B-6.84B-4.12B-260.64M570.21M
Financing Cash Flow-999.41M694.16M10.69B-646.33M2.85B801.12M

GNI Group Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price2436.00
Price Trends
50DMA
2509.54
Negative
100DMA
2854.12
Negative
200DMA
2837.83
Negative
Market Momentum
MACD
-21.17
Negative
RSI
48.68
Neutral
STOCH
35.11
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:2160, the sentiment is Neutral. The current price of 2436 is above the 20-day moving average (MA) of 2415.35, below the 50-day MA of 2509.54, and below the 200-day MA of 2837.83, indicating a neutral trend. The MACD of -21.17 indicates Negative momentum. The RSI at 48.68 is Neutral, neither overbought nor oversold. The STOCH value of 35.11 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for JP:2160.

GNI Group Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
¥111.14B192.621.87%6.98%406.15%
$214.60B14.74-9.08%-65.56%-123.22%
$7.86B-0.30-43.30%2.27%22.53%-2.21%
$193.76B-252.15%-58.12%
€131.51B108.76-0.47%2.04%-102.04%
$87.69B-5.01%33.71%68.32%
¥56.80B-78.54%10.23%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:2160
GNI Group
2,436.00
-541.00
-18.17%
JP:4587
Peptidream
1,559.50
-1,242.00
-44.33%
JP:4592
SanBio Co
2,830.00
1,796.00
173.69%
JP:4565
Sosei Group
896.00
-278.00
-23.68%
JP:4593
Healios KK
492.00
293.00
147.24%
JP:4974
Takara Bio Inc.
923.00
-107.39
-10.42%

GNI Group Corporate Events

GNI Group’s Subsidiary Completes Enrollment for Key Clinical Trial
Oct 16, 2025

GNI Group Ltd. announced that its subsidiary, Gyre Therapeutics, has completed subject enrollment for a Phase 3 clinical trial of Pirfenidone Capsule, aimed at treating pneumoconiosis. This trial, conducted across 18 centers in China, evaluates the drug’s efficacy and safety over 52 weeks. The completion of enrollment marks a significant step in the development of treatments for this chronic lung disease, although the financial impact on GNI Group’s current fiscal year is expected to be minimal.

The most recent analyst rating on (JP:2160) stock is a Hold with a Yen2551.00 price target. To see the full list of analyst forecasts on GNI Group stock, see the JP:2160 Stock Forecast page.

GNI Group Advances Non-Opioid Pain Therapy with Phase 1 Trial Completion
Sep 18, 2025

GNI Group Ltd. announced the completion of subject enrollment for the Phase 1 clinical trial of CG001419, a novel non-opioid pain product candidate developed by its subsidiary Cullgen. This trial marks a significant step in offering a new class of pain signal inhibitors that could provide safer and more effective treatment options for acute and chronic pain, with plans to advance to Phase 2 trials by early next year. The financial impact on the company’s current fiscal year is expected to be minimal.

The most recent analyst rating on (JP:2160) stock is a Hold with a Yen2551.00 price target. To see the full list of analyst forecasts on GNI Group stock, see the JP:2160 Stock Forecast page.

GNI Group Ltd. Expands Global Presence Through Strategic Equity Offering
Sep 3, 2025

GNI Group Ltd. has conducted an overseas equity offering to raise growth capital, aiming to enhance its global market presence and attract international institutional investors. This strategic move is part of the company’s flexible capital strategy to support long-term shareholder value and accelerate growth. The funds will be used to explore M&A opportunities and further develop its drug portfolio, including the F351 product for liver fibrosis, while maintaining a balanced approach to future financing options.

The most recent analyst rating on (JP:2160) stock is a Hold with a Yen2551.00 price target. To see the full list of analyst forecasts on GNI Group stock, see the JP:2160 Stock Forecast page.

GNI Group Appoints New Executive Officer to Drive Global Growth
Aug 28, 2025

GNI Group Ltd. has appointed Takuya Kaneko as Executive Officer and Chief Strategy Officer, effective August 28, 2025, to strengthen its global management structure and pursue sustainable growth. Kaneko’s extensive experience in investment banking and biotechnology is expected to aid the company in expanding its revenue base in Japan and advancing its global healthcare strategies, benefiting stakeholders and contributing to the healthcare industry’s advancement.

The most recent analyst rating on (JP:2160) stock is a Hold with a Yen2735.00 price target. To see the full list of analyst forecasts on GNI Group stock, see the JP:2160 Stock Forecast page.

GNI Group Reports Q2 FY2025 Financial Results with Increased Revenue but Net Loss
Aug 14, 2025

GNI Group Ltd. reported its consolidated financial results for the second quarter of fiscal year 2025, showing a 4.4% increase in revenue compared to the previous year. However, the company experienced a decline in operating income and pre-tax profit, resulting in a net loss for the period. This financial performance may impact the company’s market positioning and stakeholder confidence as it navigates challenges in the pharmaceutical industry.

The most recent analyst rating on (JP:2160) stock is a Buy with a Yen3700.00 price target. To see the full list of analyst forecasts on GNI Group stock, see the JP:2160 Stock Forecast page.

GNI Group Increases Stake in Gyre Pharmaceuticals to Boost Corporate Value
Aug 6, 2025

GNI Group Ltd. announced that its subsidiary, Gyre Therapeutics, has acquired additional shares in Gyre Pharmaceuticals, increasing its equity interest to 69.72%. This strategic move aims to minimize profit outflows to minority shareholders and enhance the Group’s corporate value, particularly as Gyre Pharmaceuticals is set to handle the entire value chain for a new liver fibrosis drug candidate. The acquisition is expected to positively impact the Group’s financial results, although the exact effect is still under review.

The most recent analyst rating on (JP:2160) stock is a Buy with a Yen3700.00 price target. To see the full list of analyst forecasts on GNI Group stock, see the JP:2160 Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 24, 2025