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GNI Group Ltd. (JP:2160)
:2160
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GNI Group (2160) AI Stock Analysis

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JP:2160

GNI Group

(2160)

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Neutral 48 (OpenAI - 5.2)
Rating:48Neutral
Price Target:
¥2,495.00
▼(-25.96% Downside)
Action:Reiterated
Date:05/19/26
The score is held back primarily by weak recent profitability and negative operating/free cash flow despite strong revenue growth and a solid, low-leverage balance sheet. Technicals add additional pressure as the stock trades below major moving averages with negative momentum. Valuation is neutral at a ~26 P/E, offering limited offset without a provided dividend yield.
Positive Factors
High revenue growth & gross margins
Sustained TTM revenue growth of ~76.5% combined with very high gross margins (~74%) signals durable product-level economics and market demand. Over 2–6 months this underpins pricing power and the ability to scale profitable product lines once operating leverage returns, supporting long-term margin recovery.
Negative Factors
Negative operating & free cash flow
Persistently negative operating and free cash flow means the company must rely on cash reserves or external financing to fund operations and clinical programs. Over several months this raises execution and dilution risk, constrains reinvestment capacity, and can delay commercialization or pipeline advancement.
Read all positive and negative factors
Positive Factors
Negative Factors
High revenue growth & gross margins
Sustained TTM revenue growth of ~76.5% combined with very high gross margins (~74%) signals durable product-level economics and market demand. Over 2–6 months this underpins pricing power and the ability to scale profitable product lines once operating leverage returns, supporting long-term margin recovery.
Read all positive factors

GNI Group (2160) vs. iShares MSCI Japan ETF (EWJ)

GNI Group Business Overview & Revenue Model

Company Description
GNI Group Ltd. is a global biopharmaceutical enterprise dedicated to the research, development, manufacturing, and commercialization of both modern pharmaceuticals and traditional Chinese medicines. The company's lead product, Etuary, is currently...
How the Company Makes Money
GNI Group generates revenue through the development, manufacturing, and commercialization of pharmaceutical products, including therapies for respiratory and fibrotic diseases. Its revenues primarily come from the sales of its drug products, licen...

GNI Group Financial Statement Overview

Summary
Strong TTM revenue growth (+76.5%) and high gross margins (~74%) are positives, and leverage is conservative (TTM debt-to-equity ~0.10). Offsetting this, profitability and cash generation are weak with a negative TTM net margin (-8.5%), operating losses, and negative operating/free cash flow (about -¥2.5B/-¥2.9B), increasing funding and execution risk.
Income Statement
46
Neutral
Balance Sheet
72
Positive
Cash Flow
38
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue27.05B26.84B23.61B26.01B17.42B12.69B
Gross Profit19.90B19.99B18.04B22.43B14.74B11.09B
EBITDA-3.92B-1.76B2.67B14.47B2.16B2.14B
Net Income-6.01B-4.41B1.10B8.09B388.83M1.07B
Balance Sheet
Total Assets82.59B83.79B71.94B64.27B33.91B30.30B
Cash, Cash Equivalents and Short-Term Investments19.87B21.10B12.93B23.15B11.24B14.35B
Total Debt5.17B5.37B22.66B18.84B537.36M1.13B
Total Liabilities32.07B32.11B32.07B27.72B14.10B11.03B
Stockholders Equity50.03B50.15B36.45B33.79B20.97B18.86B
Cash Flow
Free Cash Flow-2.93B-2.74B-3.69B5.28B-580.20M172.78M
Operating Cash Flow-2.54B-2.41B-3.16B6.55B393.32M552.27M
Investing Cash Flow592.26M2.73B-12.89B-3.33B-4.12B2.24B
Financing Cash Flow11.02B10.47B3.22B7.17B-646.33M357.06M

GNI Group Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3370.00
Price Trends
50DMA
2969.94
Negative
100DMA
2917.80
Negative
200DMA
2704.05
Negative
Market Momentum
MACD
-83.47
Negative
RSI
36.62
Neutral
STOCH
27.95
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:2160, the sentiment is Negative. The current price of 3370 is above the 20-day moving average (MA) of 2705.45, above the 50-day MA of 2969.94, and above the 200-day MA of 2704.05, indicating a bearish trend. The MACD of -83.47 indicates Negative momentum. The RSI at 36.62 is Neutral, neither overbought nor oversold. The STOCH value of 27.95 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:2160.

GNI Group Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
¥137.76B-14.352.18%-10.48%-1022.09%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
¥23.72B-32.28-11.11%-187.80%
48
Neutral
¥140.68B-23.35-10.40%17.67%-496.13%
47
Neutral
¥90.89B-8.92-19.31%10.88%-327.56%
42
Neutral
¥93.75B-23.82-253.07%-25.72%
41
Neutral
¥121.06B-33.74-10.16%-59.19%-124.16%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:2160
GNI Group
2,520.00
-1,300.00
-34.03%
JP:4587
Peptidream
932.50
-728.00
-43.84%
JP:4592
SanBio Co
1,201.00
-2,019.00
-62.70%
JP:4565
Sosei Group
983.00
63.00
6.85%
JP:4974
Takara Bio Inc.
1,144.00
358.00
45.55%
JP:7774
Japan Tissue Engineering Co., Ltd.
584.00
-27.00
-4.42%

GNI Group Corporate Events

GNI Group Announces Transformational Acquisition of Ayumi Pharmaceutical Holdings
Jun 5, 2026
GNI Group Ltd. has announced a transformational acquisition of Ayumi Pharmaceutical Holdings, signaling a strategic move to expand its presence in the pharmaceutical industry. The deal is framed as a significant step in enhancing GNI’s portf...
GNI Group to Buy AYUMI Pharmaceutical Holdings and Issue New Shares to Bolster Japan Platform
Jun 5, 2026
GNI Group has agreed to acquire all shares of AYUMI Pharmaceutical Holdings KK, a Japan-based holding company with a strong sales network to medical institutions and a robust earnings base anchored by Calonal and other high-share products in ortho...
GNI Group to Gain New Largest Shareholder via AYUMI Pharma Deal
Jun 5, 2026
GNI Group has announced that BCP Asia AYM Holding (Cayman) L.P., an investment vehicle ultimately linked to Blackstone-managed private equity funds, is expected to become its new largest major shareholder. This shift will occur through a third-par...
GNI Group Outlines Q1 FY2026 Results and Financial Highlights
May 15, 2026
GNI Group has released its Q1 FY2026 financial results presentation, outlining segment performance, overall financial highlights, and supplementary materials for the period. While detailed figures are not disclosed in the text provided, the releas...
GNI Group Widens Q1 Loss as Drug Investment and Reorganization Weigh on Earnings
May 15, 2026
GNI Group reported first-quarter fiscal 2026 revenue of ¥5.53 billion, a modest 3.9% year-on-year increase, but posted a significantly wider operating loss of ¥2.75 billion and a net loss attributable to owners of the parent of ¥2.1...
GNI Group’s F351 Liver Fibrosis Drug Wins NDA Acceptance and Priority Review in China
May 12, 2026
GNI Group announced that its subsidiary Gyre Pharmaceuticals has received formal acceptance from China’s National Medical Products Administration for the New Drug Application of F351, or hydronidone, for chronic hepatitis B-induced liver fib...
Gyre Ramps Up F351 and Cullgen Investments as Q1 Swings to Loss
May 8, 2026
Gyre Therapeutics, a consolidated subsidiary of GNI Group, reported first-quarter fiscal 2026 revenue of US$22.5 million, essentially flat year on year, but swung from an operating profit of US$2.3 million to an operating loss of US$9.4 million. T...
GNI Group Reshapes Top Management as Gyre Advances Cullgen Acquisition
May 7, 2026
GNI Group has strengthened its management structure as Gyre Therapeutics, a consolidated subsidiary, advances the acquisition of Cullgen, with Gyre having filed a related report with the U.S. Securities and Exchange Commission. In tandem with this...
GNI Group’s Gyre Therapeutics Completes US$300 Million Cullgen Acquisition to Build Integrated U.S.-China Biopharma Platform
May 7, 2026
Gyre Therapeutics, a consolidated subsidiary of GNI Group, has completed the all-stock acquisition of clinical-stage biopharmaceutical firm Cullgen Inc., making it a wholly owned subsidiary in a deal valued at about US$300 million. The transaction...
GNI Group Starts Phase 2/3 Trial of Pirfenidone for Cancer-Related Lung Injury in China
Apr 20, 2026
GNI Group’s subsidiary Gyre Pharmaceuticals has enrolled the first patient in a Phase 2/3 clinical trial in China evaluating its self-developed pirfenidone capsules, Etuary, for the new indication of radiation-induced lung injury with or wit...
GNI Group Issues Revenue-Only Forecast for 2026 Amid Regulatory Uncertainty
Apr 1, 2026
GNI Group has for the first time released a revenue forecast for the fiscal year ending December 31, 2026, projecting consolidated sales of ¥27.2 billion based on existing businesses that are not contingent on regulatory outcomes. The guidanc...
GNI Group Maintains Core Leadership, Adds New Outside Director After AGM
Mar 26, 2026
GNI Group has reaffirmed its leadership structure following the 25th Annual General Meeting of Shareholders held on March 26, 2026. Ying Luo was reappointed as director and continues as representative executive officer, president and CEO, while ke...
GNI Group Showcases Leadership in Fibrosis Therapies With Key China Designations
Mar 26, 2026
GNI Group has highlighted its core strengths in developing novel therapies for fibrotic conditions, led by its flagship product Etuary (pirfenidone) for pulmonary fibrosis, the first Class 1.1 new drug approved in China. The company also emphasize...
GNI Group Moves Closer to Commercialization With China NDA for Liver Fibrosis Drug F351
Mar 24, 2026
GNI Group’s U.S. affiliate Gyre Therapeutics has submitted a New Drug Application in China for F351, the group’s lead candidate for treating liver fibrosis caused by chronic hepatitis B. The filing with the National Medical Products Ad...
GNI Group Wins Priority Review in China for Hepatitis B–Related Liver Fibrosis Drug
Mar 18, 2026
GNI Group’s subsidiary Gyre Therapeutics has secured Priority Review designation from China’s National Medical Products Administration for F351, a drug candidate targeting liver fibrosis caused by chronic hepatitis B. The designation f...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 19, 2026