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Inhibrx Biosciences, Inc. (INBX)
NASDAQ:INBX
US Market

Inhibrx Biosciences Inc (INBX) AI Stock Analysis

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INBX

Inhibrx Biosciences Inc

(NASDAQ:INBX)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$76.00
▼(-10.92% Downside)
The score is held down primarily by weak financial performance (minimal revenue, large losses, and substantial negative operating/free cash flow). Technicals are mixed with soft near-term momentum, and valuation is constrained by negative earnings and no dividend. Offsetting these risks, corporate updates are constructive with positive study results and a clear regulatory/timeline catalyst path into 2026.
Positive Factors
Positive pivotal data & regulatory path
Topline ChonDRAgon results showing improved progression-free survival and a planned Q2 2026 BLA create a durable regulatory catalyst. Demonstrating first-in-disease efficacy in chondrosarcoma materially strengthens approval prospects and long-term commercial optionality if regulatory discussions proceed.
Pipeline breadth and clinical progress
Multiple advancing programs (INBRX-106 enrollment progress, ozekibart cohorts with high response rates) reduce single-bet risk and increase probability of at least one development success. Diversified indications and combination data with established agents enhance strategic partnering and long-term value creation.
Improved leverage and low absolute debt
Current leverage is modest versus prior peak levels, lowering near-term solvency risk and providing more financial flexibility to fund clinical milestones. A lighter debt burden reduces fixed obligations and the immediate pressure to secure dilutive financing, supporting execution through key catalysts.
Negative Factors
Minimal revenue and large accumulated losses
Very low recurring revenue relative to substantial net losses means the business is not self-sustaining. Persistent operating deficits limit reinvestment capacity, necessitate external funding, and create dilution and execution risk until commercial revenues from approvals materialize, impacting long-term stability.
High cash burn and negative operating cash flow
Deeply negative operating and free cash flow reflect a high-burn R&D model that depends on outside capital. This structural cash consumption raises the probability of future financing rounds, forces program prioritization, and can delay timelines if capital markets tighten, impacting durable execution.
Weak income statement quality & shrinking revenues
Negative gross profit and multi-year revenue decline indicate structural issues converting R&D into commercial economics. Reported profit driven by non-operating items is not a durable earnings base, leaving material uncertainty about sustainable margins and the firm's ability to generate operating profits post-launch.

Inhibrx Biosciences Inc (INBX) vs. SPDR S&P 500 ETF (SPY)

Inhibrx Biosciences Inc Business Overview & Revenue Model

Company DescriptionInhibrx Biosciences, Inc., a clinical-stage biopharmaceutical company, engages in the development of biologic therapeutics for people with life-threatening conditions. Its therapeutic candidates includes INBRX-109, a tetravalent therapeutic candidate targeting death-receptor 5 that is in phase 2 clinical trial for the treatment of unresectable or metastatic conventional chondrosarcoma; and INBRX-106, a hexavalent sdAb-based therapeutic candidate targeting OX4 that is in phase 2 clinical trial for the treatment of metastatic solid tumor, non-small cell lung cancer, melanoma, head and neck cancer, gastric (GIST) and gastroesophageal adenocarcinoma (GEA) cancer, renal cell carcinoma, and urothelial (transitional) cell carcinoma. The company was incorporated in 2024 and is based in La Jolla, California.
How the Company Makes MoneyInhibrx Biosciences generates revenue primarily through partnerships and collaborations with larger pharmaceutical companies, where it licenses its drug candidates in exchange for upfront payments, milestone payments, and royalties on future sales. These collaborations often provide the necessary funding for further development of its therapeutic candidates. Additionally, Inhibrx may receive grant funding or other financial support from governmental agencies or non-profit organizations aimed at advancing clinical research. As the company progresses its candidates through clinical trials and potentially toward commercialization, successful outcomes can lead to significant financial returns from both licensing agreements and eventual product sales.

Inhibrx Biosciences Inc Financial Statement Overview

Summary
Financial profile is weak: very small TTM revenue ($1.4M), large TTM net loss (~$155M), negative gross profit, and heavy cash burn (TTM operating cash flow ~-$143M). Balance sheet leverage is currently modest (debt-to-equity ~0.19) and improved versus 2022–2023, but underlying profitability and self-funding capacity remain poor.
Income Statement
18
Very Negative
Income statement quality is weak. TTM (Trailing-Twelve-Months) revenue is very small ($1.4M) and profitability is deeply negative (net loss of ~$155M), with negative gross profit indicating costs running ahead of revenue. The multi-year trend also shows revenue shrinking sharply from 2020 to 2024, and while 2024 shows a large reported profit, it is not supported by operating performance given continued heavy operating losses and negative operating cash flow, suggesting the profit was likely driven by non-operating items and is not a durable earnings base.
Balance Sheet
54
Neutral
Balance sheet is mixed but improved versus earlier years. Leverage in TTM (Trailing-Twelve-Months) looks manageable (debt-to-equity ~0.19) and total debt is low (~$7.0M) relative to assets (~$177M). However, profitability on equity is very weak (TTM return on equity around -1.86), and the company previously carried much higher leverage in 2022–2023 (debt-to-equity above 3x, peaking near 4.8x), which highlights balance-sheet volatility and reliance on financing over time.
Cash Flow
22
Negative
Cash flow profile is pressured. TTM (Trailing-Twelve-Months) operating cash flow is deeply negative (~-$143M) and free cash flow is similarly negative, consistent with a high cash burn business model. While free cash flow shows an improvement versus the prior period (positive growth rate), cash generation remains firmly negative and not self-funding; the company will likely continue to depend on external capital unless spending moderates materially or revenues scale.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.40M200.00K1.80M2.19M7.13M12.81M
Gross Profit-1.21M-2.08M609.00K-107.99M4.44M-60.69M
EBITDA-143.47M1.70B-206.69M-125.82M-75.37M-63.80M
Net Income-155.09M1.69B-241.36M-145.23M-81.77M-75.64M
Balance Sheet
Total Assets177.47M180.77M307.89M290.88M150.45M143.74M
Cash, Cash Equivalents and Short-Term Investments153.09M152.60M277.92M273.87M131.30M128.66M
Total Debt6.99M8.05M210.14M207.10M72.14M37.45M
Total Liabilities140.64M47.18M264.39M232.82M98.07M68.27M
Stockholders Equity36.83M133.58M43.50M58.06M52.38M75.47M
Cash Flow
Free Cash Flow-143.44M-197.01M-197.90M-115.99M-81.19M-49.33M
Operating Cash Flow-143.39M-194.41M-193.31M-115.30M-80.32M-47.97M
Investing Cash Flow-44.00K-2.60M-4.59M-686.00K-809.00K-1.36M
Financing Cash Flow100.19M71.68M201.96M258.55M83.77M166.46M

Inhibrx Biosciences Inc Technical Analysis

Technical Analysis Sentiment
Positive
Last Price85.32
Price Trends
50DMA
79.61
Positive
100DMA
64.26
Positive
200DMA
41.24
Positive
Market Momentum
MACD
0.35
Negative
RSI
62.14
Neutral
STOCH
72.89
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For INBX, the sentiment is Positive. The current price of 85.32 is above the 20-day moving average (MA) of 75.35, above the 50-day MA of 79.61, and above the 200-day MA of 41.24, indicating a bullish trend. The MACD of 0.35 indicates Negative momentum. The RSI at 62.14 is Neutral, neither overbought nor oversold. The STOCH value of 72.89 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for INBX.

Inhibrx Biosciences Inc Risk Analysis

Inhibrx Biosciences Inc disclosed 87 risk factors in its most recent earnings report. Inhibrx Biosciences Inc reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Inhibrx Biosciences Inc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
75
Outperform
$1.59B68.539.28%1112.27%
62
Neutral
$1.03B14.5166.76%-10.26%144.62%
56
Neutral
$322.25M-10.58-70.17%68.53%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$479.63M-1.69-67.63%-91.16%-112.24%
49
Neutral
$1.20B-8.31-144.07%
45
Neutral
$196.86M-4.1982.23%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
INBX
Inhibrx Biosciences Inc
85.08
72.17
559.02%
PRTA
Prothena
8.78
-5.71
-39.41%
CTMX
CytomX Therapeutics
6.07
5.21
605.81%
HUMA
Humacyte
1.00
-3.37
-77.14%
GLUE
Monte Rosa Therapeutics
20.93
14.26
213.79%
CADL
Candel Therapeutics
5.92
-1.89
-24.20%

Inhibrx Biosciences Inc Corporate Events

Business Operations and StrategyProduct-Related Announcements
Inhibrx Biosciences Updates on Clinical Trials Progress
Positive
Dec 16, 2025

Inhibrx Biosciences announced updates on its clinical trials for INBRX-106 and ozekibart. The INBRX-106 Phase 2/3 trial, in combination with Keytruda, is progressing with 46 out of 60 patients enrolled for treating head and neck squamous cell carcinoma, with data expected to mature by the second half of 2026. The ozekibart trials have completed enrollment for colorectal cancer and are progressing for Ewing sarcoma, with potential discussions for accelerated FDA approval in 2026.

The most recent analyst rating on (INBX) stock is a Hold with a $100.00 price target. To see the full list of analyst forecasts on Inhibrx Biosciences Inc stock, see the INBX Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Inhibrx Biosciences Reports Positive ChonDRAgon Study Results
Positive
Oct 23, 2025

On October 23, 2025, Inhibrx Biosciences announced positive topline results from its ChonDRAgon study, showing that ozekibart significantly improved median progression-free survival in patients with advanced chondrosarcoma compared to placebo. This marks the first investigational therapy to demonstrate such benefits in this disease, which lacks approved systemic treatments. The company also reported promising interim data from expansion cohorts for colorectal cancer and Ewing sarcoma, indicating high response and disease control rates in heavily pretreated patients. Inhibrx plans to file a biologics license application with the FDA in the second quarter of 2026, potentially enhancing its positioning in the oncology market.

The most recent analyst rating on (INBX) stock is a Hold with a $38.00 price target. To see the full list of analyst forecasts on Inhibrx Biosciences Inc stock, see the INBX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 14, 2026