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Immunome, Inc. (IMNM)
NASDAQ:IMNM
US Market
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Immunome (IMNM) AI Stock Analysis

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IMNM

Immunome

(NASDAQ:IMNM)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$22.00
▼(-10.68% Downside)
Action:Reiterated
Date:05/14/26
The score is primarily held down by weak financial performance driven by heavy cash burn and large losses alongside declining revenue, despite low leverage. Technicals are mixed with neutral-to-soft momentum, and valuation support is limited because the company is unprofitable and no dividend yield is provided.
Positive Factors
NDA submission & Phase 3 success
A successful Phase 3 and NDA submission for varegacestat is a structural milestone: it converts a program from R&D to potential commercial product, materially changing cash generation prospects, partner leverage, and long-term revenue optionality if approved and launched.
Negative Factors
Heavy operating cash burn
Persistent, large negative operating and free cash flows create durable funding pressure. Even with runway guidance, the magnitude and worsening trend of cash burn elevate dilution and financing risk, forcing dependence on external capital or partnership monetization.
Read all positive and negative factors
Positive Factors
Negative Factors
NDA submission & Phase 3 success
A successful Phase 3 and NDA submission for varegacestat is a structural milestone: it converts a program from R&D to potential commercial product, materially changing cash generation prospects, partner leverage, and long-term revenue optionality if approved and launched.
Read all positive factors

Immunome (IMNM) vs. SPDR S&P 500 ETF (SPY)

Immunome Business Overview & Revenue Model

Company Description
Immunome, Inc., a biopharmaceutical company, discovers and develops antibody therapeutics for oncology and infectious disease. The company's lead oncology program includes IMM-ONC-01, which targets IL-38 tumor-derived immune checkpoint capable of ...
How the Company Makes Money
Immunome primarily generates revenue through (1) collaboration and licensing arrangements with other pharmaceutical/biotechnology companies, which may include upfront payments, research funding, milestone payments tied to development/regulatory ac...

Immunome Financial Statement Overview

Summary
Overall financials are weak: steeply negative profitability and worsening cash burn (TTM operating cash flow -$196.5M; TTM free cash flow -$205.5M) outweigh the balance-sheet strength. The main positive is very low leverage (minimal debt vs. sizable equity), but revenue has declined materially into TTM and losses remain very large.
Income Statement
18
Very Negative
Balance Sheet
70
Positive
Cash Flow
22
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue4.01M6.94M9.04M14.02M0.000.00
Gross Profit-46.65M3.99M9.04M14.02M0.000.00
EBITDA-233.29M-211.16M-151.35M-28.00M-36.27M-24.45M
Net Income-224.59M-212.39M-292.96M-106.81M-36.90M-24.71M
Balance Sheet
Total Assets619.79M683.19M240.24M148.54M24.05M57.92M
Cash, Cash Equivalents and Short-Term Investments582.69M653.48M217.30M138.14M20.32M49.23M
Total Debt3.69M3.85M4.83M1.65M291.00K317.00K
Total Liabilities31.11M48.84M59.08M28.66M7.39M9.74M
Stockholders Equity588.69M634.34M181.16M119.88M16.65M48.19M
Cash Flow
Free Cash Flow-205.52M-200.60M-164.30M-8.40M-28.94M-18.30M
Operating Cash Flow-196.50M-190.92M-110.79M-7.57M-28.69M-18.23M
Investing Cash Flow43.70M60.80M-85.06M-30.48M-248.00K-79.00K
Financing Cash Flow477.99M640.36M240.53M116.41M32.00K27.77M

Immunome Technical Analysis

Technical Analysis Sentiment
Positive
Last Price24.63
Price Trends
50DMA
22.01
Negative
100DMA
22.35
Negative
200DMA
18.47
Positive
Market Momentum
MACD
-0.32
Positive
RSI
47.38
Neutral
STOCH
59.74
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For IMNM, the sentiment is Positive. The current price of 24.63 is above the 20-day moving average (MA) of 22.33, above the 50-day MA of 22.01, and above the 200-day MA of 18.47, indicating a neutral trend. The MACD of -0.32 indicates Positive momentum. The RSI at 47.38 is Neutral, neither overbought nor oversold. The STOCH value of 59.74 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for IMNM.

Immunome Risk Analysis

Immunome disclosed 75 risk factors in its most recent earnings report. Immunome reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Immunome Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
$1.58B-9.66-56.07%3.42%-11.04%
52
Neutral
$2.93B-16.50-41.54%39.04%32.40%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$2.45B-11.49-51.15%-63.29%25.39%
47
Neutral
$1.56B-4.88-45.47%-72.09%-754.83%
47
Neutral
$821.15M-68.46-28.90%68.64%50.57%
43
Neutral
$854.36M-4.22-161.87%-6.15%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IMNM
Immunome
21.66
13.06
151.86%
GERN
Geron
1.28
-0.17
-11.72%
IMTX
Immatics
11.62
6.51
127.40%
TNGX
Tango Therapeutics
20.24
18.19
887.32%
TSHA
Taysha Gene Therapies
5.49
2.89
111.15%
SANA
Sana Biotechnology
3.07
1.07
53.50%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 14, 2026