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Dianthus Therapeutics (DNTH)
NASDAQ:DNTH

Dianthus Therapeutics (DNTH) AI Stock Analysis

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DNTH

Dianthus Therapeutics

(NASDAQ:DNTH)

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Neutral 66 (OpenAI - 5.2)
Rating:66Neutral
Price Target:
$89.00
▲(3.49% Upside)
Action:ReiteratedDate:03/27/26
The score is supported most by strong technical momentum and highly positive recent corporate developments that substantially strengthen liquidity and trial execution prospects. Offsetting these strengths are deteriorating operating results and increased cash burn, with valuation also constrained by ongoing losses (negative P/E).
Positive Factors
Cash runway / capital base
A pro forma cash balance near $1.2B provides durable financial flexibility to fund multiple clinical programs and pivotal trials without immediate refinancing. This reduces short-term solvency risk, supports parallel development, and allows strategic choices on program sequencing and partnering.
Negative Factors
Rising cash burn
Operating cash flow deteriorated materially year-over-year, signaling growing cash consumption to support expanded trials. Persistently negative cash generation forces dependence on financing, constrains optionality for non-core investments, and can pressure program funding sequencing if costs remain elevated.
Read all positive and negative factors
Positive Factors
Negative Factors
Cash runway / capital base
A pro forma cash balance near $1.2B provides durable financial flexibility to fund multiple clinical programs and pivotal trials without immediate refinancing. This reduces short-term solvency risk, supports parallel development, and allows strategic choices on program sequencing and partnering.
Read all positive factors

Dianthus Therapeutics (DNTH) vs. SPDR S&P 500 ETF (SPY)

Dianthus Therapeutics Business Overview & Revenue Model

Company Description
Dianthus Therapeutics, Inc. operates as a clinical-stage biotechnology company that designs, develops, and delivers novel monoclonal antibodies for people living with severe autoimmune and inflammatory diseases. It develops DNTH103 that is in phas...
How the Company Makes Money
Dianthus Therapeutics does not appear to generate meaningful recurring revenue from product sales because its programs are in clinical development and it has no approved products. As a result, its operations are primarily funded through financing ...

Dianthus Therapeutics Financial Statement Overview

Summary
Financials are mixed: the balance sheet is a strength with very low leverage (debt-to-equity ~0.003), but operating fundamentals are weak with sharply wider 2025 losses (net loss ~$162.3M vs. ~$84.9M in 2024), small/volatile revenue (down ~34% in 2025), and rising cash burn (operating cash flow about -$129.1M in 2025 vs. -$78.2M in 2024).
Income Statement
18
Very Negative
Balance Sheet
72
Positive
Cash Flow
24
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue2.04M6.24M2.83M6.42M1.48M
Gross Profit2.04M6.24M2.83M6.42M1.48M
EBITDA-177.93M-101.45M-47.82M-29.56M-13.09M
Net Income-162.34M-84.97M-43.55M-28.48M-13.11M
Balance Sheet
Total Assets530.92M374.01M179.41M83.11M189.93M
Cash, Cash Equivalents and Short-Term Investments404.30M275.24M173.72M75.49M176.93M
Total Debt1.39M1.49M585.00K788.00K0.00
Total Liabilities37.52M21.53M10.54M9.45M17.26M
Stockholders Equity493.40M352.48M168.87M73.66M172.67M
Cash Flow
Free Cash Flow-129.27M-78.28M-36.97M-29.21M-60.80M
Operating Cash Flow-129.06M-78.18M-36.86M-29.07M-59.53M
Investing Cash Flow-122.83M-286.81M20.25M-59.82M43.43M
Financing Cash Flow280.13M255.62M133.57M96.68M89.60M

Dianthus Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price86.00
Price Trends
50DMA
63.26
Positive
100DMA
52.45
Positive
200DMA
39.90
Positive
Market Momentum
MACD
6.14
Positive
RSI
71.27
Negative
STOCH
76.29
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DNTH, the sentiment is Positive. The current price of 86 is above the 20-day moving average (MA) of 80.19, above the 50-day MA of 63.26, and above the 200-day MA of 39.90, indicating a bullish trend. The MACD of 6.14 indicates Positive momentum. The RSI at 71.27 is Negative, neither overbought nor oversold. The STOCH value of 76.29 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DNTH.

Dianthus Therapeutics Risk Analysis

Dianthus Therapeutics disclosed 72 risk factors in its most recent earnings report. Dianthus Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Dianthus Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
66
Neutral
$4.55B-9.59-42.64%-39.78%
61
Neutral
$3.58B-12.72-31.97%-5.73%
52
Neutral
$1.65B-7.89-57.52%-100.34%52.85%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$902.74M-7.53-11.55%-23.37%-42.45%
49
Neutral
$1.46B-22.81-40.63%58.12%24.08%
44
Neutral
$1.47B-1.64-688.89%18.76%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DNTH
Dianthus Therapeutics
86.00
70.39
450.93%
ARDX
Ardelyx
5.94
1.49
33.48%
EWTX
Edgewise Therapeutics
33.33
21.50
181.74%
JANX
Janux Therapeutics Inc
14.84
-9.54
-39.13%
AMLX
Amylyx Pharmaceuticals Inc
14.95
11.49
332.08%
BHVN
Biohaven Ltd.
9.80
-8.11
-45.28%

Dianthus Therapeutics Corporate Events

Business Operations and StrategyFinancial DisclosuresRegulatory Filings and Compliance
Dianthus Highlights Strong Cash Runway and Streamlined Trials
Positive
Mar 26, 2026
On March 26, 2026, Dianthus Therapeutics posted an updated corporate presentation outlining progress on its autoimmune pipeline and financial position. The company reported pro forma cash of about $1.2 billion, providing runway into 2030 to advanc...
Private Placements and FinancingRegulatory Filings and Compliance
Dianthus Therapeutics Announces Major Public Equity Offering
Positive
Mar 12, 2026
On March 10, 2026, Dianthus Therapeutics, Inc. entered into an underwriting agreement with a syndicate of investment banks to launch a public offering of 7,313,582 shares of common stock at $81.00 per share and pre-funded warrants equivalent to 40...
Business Operations and StrategyFinancial Disclosures
Dianthus Advances Claseprubart With Positive Phase 3 Update
Positive
Mar 9, 2026
On March 9, 2026, Dianthus Therapeutics reported fourth-quarter and full-year 2025 results and highlighted an early GO decision in its Phase 3 CAPTIVATE trial of claseprubart in chronic inflammatory demyelinating polyneuropathy, after meeting resp...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 27, 2026