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GPCR Stock Chart & Stats
$49.12
-$1.68(-3.31%)
At close: 4:00 PM EDT
$49.12
-$1.68(-3.31%)
Day’s Range― - ―
52-Week Range$15.80 - $94.90
Previous CloseN/A
Volume655.41K
Average Volume (3M)749.96K
Market Cap
$3.41B
Enterprise Value$2.04K
Total Cash (Recent Filing)$1.46B
Total Debt (Recent Filing)$5.79M
Price to Earnings (P/E)―
Beta0.91
Next Earnings
Aug 06, 2026EPS Estimate
-0.38Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-2.64
Shares Outstanding71,074,520
10 Day Avg. Volume595,420
30 Day Avg. Volume749,963
Financial Highlights & Ratios
PEG Ratio-11.30
Price to Book (P/B)2.72
Price to Sales (P/S)0.00
P/FCF Ratio-18.23
Enterprise Value/Market Cap<0.01
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit>-0.01
Enterprise Value/Ebitda>-0.01
Forecast
1Y Price Target
$110.17Price Target Upside124.28% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering8
EPS Forecast (FY)-1.43
Revenue Forecast (FY)$38.46M
Bulls Say, Bears Say
Bulls Say
Strong Balance Sheet / Low LeverageA large equity base and minimal debt provide structural financial flexibility to fund multi-year R&D programs without near-term solvency pressure. This reduces refinancing risk, preserves optionality for strategic moves, and supports sustained investment in clinical development.
Robust Phase 2 Obesity Efficacy And Regulatory PathStrong placebo-adjusted efficacy and favorable FDA end-of-Phase-2 feedback materially de-risks the obesity program versus earlier-stage peers. This advances the company toward Phase 3 timing and strengthens the long-term commercial potential of an oral obesity therapy, a durable industry opportunity.
Multi-year Cash RunwayA reported $1.5B cash balance projected to fund operations into 2028 gives the company time to complete late-stage planning and early pivotal work without immediate market dependency, enabling disciplined R&D execution and reducing short-term financing constraints.
Bears Say
Pre-revenue Status With Widening Operating LossesOperating losses have grown materially as the company funds clinical development, and with no product revenue, profitability depends entirely on future trial success and commercialization. This structural lack of revenue increases long-term execution risk for funding and value creation.
Persistent Heavy Cash Burn And Negative Operating Cash FlowConsistently negative operating cash flow and deteriorating free cash flow indicate accelerating spend to advance programs. Sustained cash burn elevates dependence on external financing and can constrain strategic choices if trial timelines slip or development costs rise.
Financing / Dilution Risk From Expanded ATM CapacityRemoving the cap and expanding at-the-market capacity materially increases the company's ability to raise equity, which while flexible, raises the structural risk of shareholder dilution if management taps markets. This can affect long-term capital structure and investor returns.
GPCR FAQ
What was Structure Therapeutics, Inc. Sponsored ADR’s price range in the past 12 months?
Structure Therapeutics, Inc. Sponsored ADR lowest stock price was $15.80 and its highest was $94.90 in the past 12 months.
What is Structure Therapeutics, Inc. Sponsored ADR’s market cap?
Structure Therapeutics, Inc. Sponsored ADR’s market cap is $3.41B.
When is Structure Therapeutics, Inc. Sponsored ADR’s upcoming earnings report date?
Structure Therapeutics, Inc. Sponsored ADR’s upcoming earnings report date is Aug 06, 2026 which is tomorrow.
How were Structure Therapeutics, Inc. Sponsored ADR’s earnings last quarter?
Structure Therapeutics, Inc. Sponsored ADR released its earnings results on May 07, 2026. The company reported -$0.35 earnings per share for the quarter, beating the consensus estimate of -$0.351 by $0.001.
Is Structure Therapeutics, Inc. Sponsored ADR overvalued?
According to Wall Street analysts Structure Therapeutics, Inc. Sponsored ADR’s price is currently Undervalued.
Does Structure Therapeutics, Inc. Sponsored ADR pay dividends?
Structure Therapeutics, Inc. Sponsored ADR does not currently pay dividends.
What is Structure Therapeutics, Inc. Sponsored ADR’s EPS estimate?
Structure Therapeutics, Inc. Sponsored ADR’s EPS estimate is -0.38.
How many shares outstanding does Structure Therapeutics, Inc. Sponsored ADR have?
Structure Therapeutics, Inc. Sponsored ADR has 71,074,520 shares outstanding.
What happened to Structure Therapeutics, Inc. Sponsored ADR’s price movement after its last earnings report?
Structure Therapeutics, Inc. Sponsored ADR reported an EPS of -$0.35 in its last earnings report, beating expectations of -$0.351. Following the earnings report the stock price went down -0.128%.
Which hedge fund is a major shareholder of Structure Therapeutics, Inc. Sponsored ADR?
Currently, no hedge funds are holding shares in GPCR
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Structure Therapeutics, Inc. Sponsored ADR Stock Smart Score
Underperform
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Analyst Consensus
Strong Buy
Average Price Target:
$110.17 (124.28% Upside)
$110.17 (124.28% Upside)
Blogger Sentiment
Bullish
GPCR Sentiment 86%
Sector Average ―
Sector Average ―
Hedge Fund Trend
Decreased
By 475.2K Shares
Last Quarter.
Last Quarter.
Insider Transactions
Sold Shares
Worth $1.1M over
the Last 3 Months
the Last 3 Months
Crowd Wisdom
Very Negative
Last 7 Days ▼ 1.6%
Last 30 Days ▼ 5.9%
Last 30 Days ▼ 5.9%
Technicals
SMA
Negative
20 days / 200 days
Momentum
171.40%
12-Months-Change
Fundamentals
Return on Equity
―
Trailing 12-Months
Asset Growth
74.04%
Trailing 12-Months
Company Description
Structure Therapeutics, Inc. Sponsored ADR
Structure Therapeutics Inc., an international biopharmaceutical company currently in its clinical development phase, is committed to creating and providing groundbreaking oral therapies for various chronic diseases that lack adequate treatment options. The company's primary investigational drug, GSBR-1290, is an orally administered, biased small molecule agonist designed to target the glucagon-like-peptide-1 receptor (GLP-1R). This G-protein-coupled receptor (GPCR) is a recognized and validated therapeutic target for managing both type-2 diabetes mellitus and obesity. Furthermore, Structure Therapeutics is developing other oral small molecule treatments that act on different GPCRs, addressing pulmonary and cardiovascular conditions. For example, ANPA-0073 is a biased agonist aimed at the apelin receptor, a GPCR linked to diseases like idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension. Another compound in their pipeline is LTSE-2578, an oral small molecule that acts as a lysophosphatidic acid 1 receptor antagonist, also being explored for the treatment of IPF. Established in 2016, the company was formerly known as ShouTi Inc. and is headquartered in South San Francisco, California.
GPCR Stock 12 Month Forecast
Average Price Target
$110.17
▲(124.28% Upside)
Technical Analysis
Ownership Overview
10.08% Insiders
26.29% Mutual Funds
0.48% Other Institutional Investors
61.83% Public Companies and Individual Investors










