Clinical EfficacyPhase 1b results showed robust and durable molecular responses to ELVN-001 across tested doses, indicating meaningful clinical activity in patients who had received prior therapies.
Differentiated MechanismELVN-001 inhibits the ATP-binding pocket, offering a distinct mechanism that enables treatment of patients resistant to several other BCR::ABL1 inhibitors and strengthens competitive positioning.
Safety And Dose FlexibilityNo new safety signals were observed and the tolerability profile supported flexible dose selection, which can simplify regimen decisions in later-stage trials.