Buy Rating for Structure Therapeutics, Inc.: Potential Disruption in Obesity Treatment with Amylin AgonistsAt obesity week 2025, Lilly’s (NYSE: LLY) eloralinde (Q W, injectable amylin agonist) impressed the field and demonstrated compelling semaglude-lik e efficacy coupled with prisne GI-t olerability in the monotherapy seng in a Phase 2 study (n=263). As a result, we thought it suitable to conduct a 20-slide “cold plunge” on amylin, which is more to-the-point than a tradional “ deep dive” (and hopefully more therapeuc), t o evaluate how this class might fit into the highly compev e obesity arena. Within, we discuss the amylin mechanism relav e to that of glucagon-like pepde-1 (GLP -1), analyze the clinical-stage compev e landscape, and evaluate the potenal f or Structure’s (NASDAQ: GPCR) small molecule amylin agonists (ACCG- 2671 and ACCG-3535) as they approach the clinic.