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Glaukos (GKOS)
NYSE:GKOS

Glaukos (GKOS) AI Stock Analysis

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GKOS

Glaukos

(NYSE:GKOS)

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Neutral 61 (OpenAI - 4o)
Rating:61Neutral
Price Target:
$105.00
▼(-1.75% Downside)
Glaukos's strong sales growth and strategic product developments are significant positives. However, profitability challenges and valuation concerns weigh on the overall score. The technical indicators suggest bullish momentum, but caution is advised due to overbought signals.
Positive Factors
Revenue Growth
Strong revenue growth indicates robust demand for Glaukos's products, enhancing its market position and supporting future expansion.
Product Innovation
FDA approval of Epioxa strengthens Glaukos's product portfolio, potentially increasing market share and driving long-term revenue growth.
Strategic Focus
Commitment to innovation and strategic focus on commercial excellence positions Glaukos for sustained competitive advantage in the ophthalmic sector.
Negative Factors
Profitability Challenges
Persistent profitability issues may hinder Glaukos's ability to reinvest in growth and innovation, impacting long-term financial health.
Cash Flow Constraints
Operational cash constraints can limit Glaukos's ability to fund new projects and manage financial obligations, affecting sustainability.
Market Access Challenges
Market access challenges for new products like Epioxa could delay revenue realization and affect Glaukos's competitive positioning.

Glaukos (GKOS) vs. SPDR S&P 500 ETF (SPY)

Glaukos Business Overview & Revenue Model

Company DescriptionGlaukos Corporation, an ophthalmic medical technology and pharmaceutical company, focuses on the development of novel therapies for the treatment of glaucoma, corneal disorders, and retinal diseases. It offers iStent, iStent inject, iStent inject W micro-bypass stents that enhance aqueous humor outflow inserted in cataract surgery to treat mild-to-moderate open-angle glaucoma. The company's product pipeline includes iStent Infinite, a three stents product that is designed for use as a standalone procedure in patients with refractory glaucoma; and iDose TR, a targeted injectable implant based on its micro-scale device-platform that is designed to deliver therapeutic levels of medication. The company markets its products through direct sales organization, as well as through distributors in the United States and internationally. Glaukos Corporation was incorporated in 1998 and is headquartered in San Clemente, California.
How the Company Makes MoneyGlaukos generates revenue primarily through the sale of its medical devices and surgical products for the treatment of glaucoma. The company's key revenue streams include direct sales of its iStent and iStent inject devices, which are used in minimally invasive surgical procedures. Additionally, Glaukos may receive revenue from partnerships and collaborations with healthcare providers and institutions that utilize its products in clinical settings. The company benefits from a growing patient population with glaucoma and increased adoption of MIGS procedures, which contributes to its earnings. Strategic partnerships with ophthalmic practices and health systems also play a significant role in expanding its market presence and driving sales.

Glaukos Earnings Call Summary

Earnings Call Date:Oct 29, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 19, 2026
Earnings Call Sentiment Positive
Glaukos showcased strong financial performance with record sales and significant product approvals, particularly the FDA approval of Epioxa. However, the company faces challenges with transitioning its Corneal Health franchise and establishing market access for new products.
Q3-2025 Updates
Positive Updates
Record Third Quarter Sales
Glaukos reported record third quarter consolidated net sales of $133.5 million, up 38% on a reported basis or 37% on a constant currency basis versus the year-ago quarter.
iDose TR Adoption
The U.S. Glaucoma franchise delivered record third quarter net sales of $80.8 million, with iDose TR generating sales of approximately $40 million in the third quarter.
Epioxa FDA Approval
FDA approved Epioxa for corneal cross-linking for keratoconus, marking a significant milestone as the first and only FDA-approved topical drug therapy that does not require the removal of the corneal epithelium.
Raised Full-Year 2025 Guidance
Full-year 2025 net sales guidance raised to $490 million to $495 million from $480 million to $486 million.
Strong International Growth
International Glaucoma franchise net sales of $29.4 million, marking a year-over-year growth of 20% on a reported basis and 17% on a constant currency basis.
Negative Updates
Corneal Health Franchise Transition
The transition from Photrexa to Epioxa may lead to a material year-over-year decline in the fourth quarter for the Corneal Health franchise.
Reimbursement and Market Access Challenges
Challenges with establishing professional fees in some MAC regions and the need for extensive payer education for Epioxa.
Epioxa Pricing Concerns
The wholesale acquisition cost for Epioxa is set at $78,500, which may lead to challenges in payer coverage and patient access.
Company Guidance
During the third-quarter 2025 earnings call, Glaukos Corporation reported record consolidated net sales of $133.5 million, marking a 38% increase on a reported basis and 37% on a constant currency basis compared to the same period last year. This performance prompted the company to raise its full-year 2025 net sales guidance from the previously projected range of $480 million to $486 million, up to $490 million to $495 million. Contributing significantly to these results was the strong adoption of iDose TR, which alone generated approximately $40 million in third-quarter sales. The U.S. Glaucoma franchise achieved record net sales of $80.8 million, reflecting a 57% year-over-year growth, while the International Glaucoma franchise delivered $29.4 million in net sales, up 20% on a reported basis. The Corneal Health franchise also grew by 13%, with net sales reaching $23.3 million. Additionally, Glaukos introduced a preliminary 2026 revenue guidance range of $600 million to $620 million, driven by ongoing momentum and the upcoming launch of Epioxa, a newly FDA-approved treatment for keratoconus.

Glaukos Financial Statement Overview

Summary
Glaukos shows potential with revenue growth and a strong gross profit margin. However, profitability issues and negative cash flow highlight significant operational inefficiencies and cash constraints.
Income Statement
45
Neutral
Glaukos shows a positive revenue growth trend with a TTM growth rate of 8.52%, indicating potential market expansion. However, the company struggles with profitability, as evidenced by negative net profit and EBIT margins. The gross profit margin remains strong at 76.87%, but the persistent negative net income highlights challenges in cost management and operational efficiency.
Balance Sheet
55
Neutral
The balance sheet reflects a stable financial structure with a low debt-to-equity ratio of 0.14, suggesting manageable leverage. However, the negative return on equity indicates inefficiencies in generating profits from shareholders' investments. The equity ratio of 76.98% shows a strong equity base, providing a cushion against financial volatility.
Cash Flow
40
Negative
Cash flow analysis reveals a challenging scenario with negative operating cash flow, indicating operational cash constraints. Despite a positive free cash flow growth rate, the company struggles to convert net income into cash, as shown by the negative operating cash flow to net income ratio. The free cash flow to net income ratio above 1 suggests reliance on non-operational cash inflows.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue469.82M383.48M314.71M282.86M294.01M224.96M
Gross Profit361.14M289.45M239.14M213.88M227.38M133.24M
EBITDA-38.86M-95.64M-82.12M-48.76M-1.47M-83.59M
Net Income-87.61M-146.37M-134.66M-99.19M-49.59M-120.35M
Balance Sheet
Total Assets999.38M974.76M940.41M1.07B1.13B1.01B
Cash, Cash Equivalents and Short-Term Investments273.71M318.92M295.43M352.69M414.05M404.37M
Total Debt104.31M105.87M383.74M382.91M383.38M272.00M
Total Liabilities229.84M207.82M478.65M544.16M541.68M338.05M
Stockholders Equity769.54M766.93M461.77M530.00M587.15M667.45M
Cash Flow
Free Cash Flow-27.61M-67.62M-78.01M-63.35M-23.08M-29.92M
Operating Cash Flow-21.13M-61.32M-57.76M-33.08M24.71M-22.99M
Investing Cash Flow-49.94M47.83M14.10M44.78M-58.23M-205.06M
Financing Cash Flow69.57M91.54M15.04M6.25M39.26M262.54M

Glaukos Technical Analysis

Technical Analysis Sentiment
Positive
Last Price106.87
Price Trends
50DMA
89.35
Positive
100DMA
89.53
Positive
200DMA
93.85
Positive
Market Momentum
MACD
6.03
Negative
RSI
73.33
Negative
STOCH
81.31
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GKOS, the sentiment is Positive. The current price of 106.87 is above the 20-day moving average (MA) of 99.18, above the 50-day MA of 89.35, and above the 200-day MA of 93.85, indicating a bullish trend. The MACD of 6.03 indicates Negative momentum. The RSI at 73.33 is Negative, neither overbought nor oversold. The STOCH value of 81.31 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GKOS.

Glaukos Risk Analysis

Glaukos disclosed 25 risk factors in its most recent earnings report. Glaukos reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Glaukos Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
75
Outperform
$1.67B25.0118.31%29.47%23.24%
65
Neutral
$2.45B29.245.18%7.81%-26.32%
63
Neutral
$3.46B-17.63%8.97%-1024.86%
61
Neutral
$6.23B-12.19%30.38%47.64%
61
Neutral
$1.42B-109.73%17.87%-57.03%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$5.75B-53.15%25.45%66.62%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GKOS
Glaukos
106.87
-36.02
-25.21%
ITGR
Integer Holdings
69.13
-71.49
-50.84%
UFPT
Ufp Technologies
210.07
-85.53
-28.93%
TNDM
Tandem Diabetes Care
20.44
-14.08
-40.79%
LIVN
LivaNova
62.67
11.18
21.71%
IRTC
Irhythm Technologies
173.63
83.70
93.07%

Glaukos Corporate Events

Product-Related AnnouncementsBusiness Operations and Strategy
Glaukos Highlights Innovation in November 2025 Presentation
Positive
Nov 10, 2025

Glaukos Corporation has announced its November 2025 Investor Presentation, highlighting its commitment to innovation in chronic eye disease treatments. The company emphasizes its strategic focus on commercial excellence and the development of groundbreaking therapies like the iDose TR, which aims to improve patient compliance and outcomes in glaucoma treatment. The presentation underscores Glaukos’s efforts to expand its market presence and enhance its product offerings, which could significantly impact its operations and industry positioning.

Business Operations and StrategyFinancial Disclosures
Glaukos Reports Record Q3 2025 Sales Growth
Positive
Oct 29, 2025

In its third quarter of 2025, Glaukos reported record net sales of $133.5 million, marking a 38% increase year-over-year. The company raised its 2025 net sales guidance and introduced preliminary 2026 guidance, reflecting strong business momentum and strategic execution. Despite a net loss, the company showed improved financial performance compared to the previous year, with increased sales, gross margins, and reduced operating losses.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 09, 2025