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Glaukos Corp. (GKOS)
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Glaukos (GKOS) AI Stock Analysis

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GKOS

Glaukos

(NYSE:GKOS)

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Neutral 46 (OpenAI - 4o)
Rating:46Neutral
Price Target:
$78.00
▲(1.18% Upside)
Glaukos's overall stock score is primarily impacted by its strong revenue growth and strategic advancements, as highlighted in the earnings call. However, significant challenges in profitability, cash flow management, and a bearish technical outlook weigh heavily on the score. The negative P/E ratio and lack of dividend yield further contribute to a lower valuation score.
Positive Factors
Revenue Growth
Strong revenue growth indicates successful market penetration and product adoption, which supports long-term business expansion.
Innovation and Product Development
Continued innovation in product development enhances competitive advantage and positions Glaukos as a leader in ophthalmic solutions.
Strong Financial Position
Maintaining a strong cash position provides financial flexibility for strategic investments and operational stability.
Negative Factors
Profitability Challenges
Ongoing profitability issues can hinder long-term growth and limit the ability to reinvest in business development.
Regulatory and Reimbursement Risks
Regulatory changes and reimbursement reductions could negatively impact revenue and profitability in key markets.
Corneal Health Franchise Challenges
Challenges in the Corneal Health franchise may affect revenue diversification and growth potential in this segment.

Glaukos (GKOS) vs. SPDR S&P 500 ETF (SPY)

Glaukos Business Overview & Revenue Model

Company DescriptionGlaukos Corporation, an ophthalmic medical technology and pharmaceutical company, focuses on the development of novel therapies for the treatment of glaucoma, corneal disorders, and retinal diseases. It offers iStent, iStent inject, iStent inject W micro-bypass stents that enhance aqueous humor outflow inserted in cataract surgery to treat mild-to-moderate open-angle glaucoma. The company's product pipeline includes iStent Infinite, a three stents product that is designed for use as a standalone procedure in patients with refractory glaucoma; and iDose TR, a targeted injectable implant based on its micro-scale device-platform that is designed to deliver therapeutic levels of medication. The company markets its products through direct sales organization, as well as through distributors in the United States and internationally. Glaukos Corporation was incorporated in 1998 and is headquartered in San Clemente, California.
How the Company Makes MoneyGlaukos generates revenue primarily through the sale of its surgical devices and related products for the treatment of glaucoma. The company's key revenue streams include the direct sales of its iStent and iStent inject devices, as well as revenue from related consumables and accessories. Glaukos also benefits from strategic partnerships with ophthalmology clinics and hospitals, which help to expand its market reach and distribution capabilities. Additionally, the company may explore partnerships with other healthcare organizations for product development, clinical studies, and co-marketing agreements, contributing to its overall revenue growth. As the prevalence of glaucoma and the demand for innovative treatment options increase, Glaukos is positioned to capitalize on these trends within the ophthalmic market.

Glaukos Earnings Call Summary

Earnings Call Date:Oct 29, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Feb 19, 2026
Earnings Call Sentiment Positive
The earnings call presented a strong performance with record sales and significant growth in key areas, particularly in the U.S. and international glaucoma franchises. However, there are notable challenges, including market turbulence from regulatory changes and proposed reimbursement reductions that could impact future growth. Overall, the highlights slightly outweigh the lowlights.
Q2-2025 Updates
Positive Updates
Record Second Quarter Consolidated Net Sales
Glaukos reported record second quarter consolidated net sales of $124.1 million, a 30% increase on a reported basis and 29% on a constant currency basis compared to the previous year.
U.S. Glaucoma Franchise Growth
The U.S. Glaucoma franchise delivered record second quarter net sales of $72.3 million, growing 45% year-over-year, driven by iDose TR which generated approximately $31 million in sales.
International Glaucoma Franchise Expansion
International net sales reached $31.3 million, marking a 20% year-over-year growth on a reported basis and 15% on a constant currency basis.
Epioxa NDA Review Progress
Important milestones were completed for Epioxa NDA review, with a PDUFA date set for October 20, 2025, potentially offering a breakthrough treatment for keratoconus patients.
Strong Financial Position
Excluding one-time investments, the company grew its cash and equivalents by more than $4 million in the second quarter.
Negative Updates
MIGS Market Headwind
The 5 MAC LCDs implemented are causing market turbulence, impacting the use of 2 MIGS surgical devices in the same procedures, expected to continue through 2025.
Corneal Health Franchise Challenges
The Corneal Health franchise saw modest growth of 4%, with anticipated disruption due to the transition from Photrexa to Epioxa.
Proposed CMS Reimbursement Reductions
CMS proposed reductions in physician fee reimbursement for certain ophthalmology procedures, which could impact economic incentives for comprehensive ophthalmologists.
Company Guidance
In the second quarter of 2025, Glaukos Corporation reported record consolidated net sales of $124.1 million, a 30% increase on a reported basis or 29% on a constant currency basis compared to the same quarter last year. This sales boost was primarily driven by the growing adoption and utilization of the iDose TR, which generated approximately $31 million in sales, contributing to a 45% year-over-year growth within the U.S. glaucoma franchise. As a result of this strong performance, Glaukos raised its full-year 2025 net sales guidance to a range of $480 million to $486 million, up from the previous range of $475 million to $485 million. The company's international glaucoma franchise also saw record net sales of $31.3 million, reflecting a 20% year-over-year growth on a reported basis and 15% on a constant currency basis. Furthermore, the Corneal Health franchise recorded net sales of $20.6 million, marking a 4% increase. Glaukos is advancing several clinical programs, including the Phase IIb/III clinical program for iDose TREX and the FDA's ongoing NDA review for Epioxa, with a PDUFA date set for October 20, 2025. The company also made strategic investments, including the acquisition of Mobius Therapeutics and purchasing a new building at its Aliso Viejo headquarters, while still managing to grow its cash and equivalents by over $4 million in the quarter.

Glaukos Financial Statement Overview

Summary
Glaukos demonstrates strong revenue growth and efficient production, but profitability remains a significant challenge due to high operating expenses. The balance sheet shows controlled leverage, yet negative returns on equity persist. Cash flow issues are evident, with negative operating and free cash flows, indicating a need for improved cash management strategies.
Income Statement
45
Neutral
Glaukos shows a consistent revenue growth trend, with a 7.03% increase in TTM. However, the company struggles with profitability, evidenced by negative net profit margins and EBIT margins. The gross profit margin remains strong, indicating efficient production, but high operating expenses are impacting overall profitability.
Balance Sheet
55
Neutral
The balance sheet reflects a stable debt-to-equity ratio, improving from previous years, which indicates controlled leverage. However, the return on equity remains negative, highlighting ongoing profitability challenges. The equity ratio is stable, suggesting a solid asset base relative to equity.
Cash Flow
40
Negative
Cash flow analysis reveals negative operating and free cash flows, with a significant decline in free cash flow growth. The free cash flow to net income ratio is positive, suggesting some efficiency in cash generation relative to net income, but overall cash flow remains a concern.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue432.95M383.48M314.71M282.86M294.01M224.96M
Gross Profit330.52M289.45M239.14M213.88M227.38M133.24M
EBITDA-62.19M-77.63M-82.12M-48.76M-1.47M-83.59M
Net Income-92.79M-146.37M-134.66M-99.19M-49.59M-120.35M
Balance Sheet
Total Assets986.96M974.76M940.41M1.00B1.05B1.01B
Cash, Cash Equivalents and Short-Term Investments274.79M318.92M295.43M352.69M414.05M404.37M
Total Debt105.02M105.87M383.74M382.48M382.38M270.81M
Total Liabilities221.85M207.82M478.65M472.38M462.55M338.05M
Stockholders Equity765.11M766.93M461.77M530.00M587.15M667.45M
Cash Flow
Free Cash Flow-26.92M-67.62M-78.01M-63.35M-23.08M-29.92M
Operating Cash Flow-20.62M-61.32M-57.76M-33.08M24.71M-22.99M
Investing Cash Flow-15.38M47.83M14.10M44.78M-58.23M-205.06M
Financing Cash Flow73.98M91.54M15.04M6.25M39.26M262.54M

Glaukos Technical Analysis

Technical Analysis Sentiment
Negative
Last Price77.09
Price Trends
50DMA
85.47
Negative
100DMA
90.88
Negative
200DMA
101.70
Negative
Market Momentum
MACD
-2.61
Positive
RSI
40.46
Neutral
STOCH
21.26
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GKOS, the sentiment is Negative. The current price of 77.09 is below the 20-day moving average (MA) of 81.94, below the 50-day MA of 85.47, and below the 200-day MA of 101.70, indicating a bearish trend. The MACD of -2.61 indicates Positive momentum. The RSI at 40.46 is Neutral, neither overbought nor oversold. The STOCH value of 21.26 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GKOS.

Glaukos Risk Analysis

Glaukos disclosed 25 risk factors in its most recent earnings report. Glaukos reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Glaukos Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
$1.46B21.9519.29%40.98%34.80%
$2.29B27.345.18%7.81%-26.32%
$5.95B-63.11-91.13%22.37%31.14%
$2.91B-13.70-17.87%8.57%-1154.64%
$7.86B-0.30-43.30%2.27%22.53%-2.21%
$1.02B-111.91%25.84%-47.67%
$4.46B-12.98%26.70%48.19%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GKOS
Glaukos
77.09
-61.59
-44.41%
ITGR
Integer Holdings
65.30
-64.64
-49.75%
UFPT
Ufp Technologies
189.37
-84.63
-30.89%
TNDM
Tandem Diabetes Care
15.15
-17.21
-53.18%
LIVN
LivaNova
53.34
2.00
3.90%
IRTC
Irhythm Technologies
185.29
109.52
144.54%

Glaukos Corporate Events

Business Operations and StrategyProduct-Related Announcements
Glaukos Highlights Innovation in Recent Investor Presentation
Positive
Aug 12, 2025

Glaukos Corporation’s recent investor presentation highlights its strategic focus on innovation and commercial excellence, aiming to improve standards of care in ophthalmology. The company is advancing its iDose TR therapy, a groundbreaking sustained-release drug delivery system for glaucoma, which is expected to enhance patient compliance and outcomes by reducing reliance on traditional topical medications.

The most recent analyst rating on (GKOS) stock is a Buy with a $139.00 price target. To see the full list of analyst forecasts on Glaukos stock, see the GKOS Stock Forecast page.

Glaukos Corp. Reports Record Growth Amid Challenges
Aug 1, 2025

Glaukos Corp. recently held its earnings call, revealing a generally positive sentiment driven by strong financial performance and strategic advancements. The company reported record net sales and significant growth in key segments, such as the U.S. glaucoma franchise and international markets. Despite these achievements, challenges persist, including the impact of MAC LCDs on the MIGS market and potential disruptions from proposed CMS reimbursement changes. Nevertheless, the company’s positive achievements and strategic advancements appear to outweigh these challenges.

Glaukos Corporation Reports Strong Q2 2025 Growth
Jul 31, 2025

Glaukos Corporation is an ophthalmic pharmaceutical and medical technology company that specializes in developing innovative therapies for glaucoma, corneal disorders, and retinal diseases. The company is known for pioneering Micro-Invasive Glaucoma Surgery (MIGS) and continues to expand its portfolio with novel, dropless platform technologies.

Business Operations and StrategyFinancial Disclosures
Glaukos Reports Record Q2 Sales, Raises 2025 Guidance
Positive
Jul 30, 2025

On July 30, 2025, Glaukos Corporation announced its financial results for the second quarter ended June 30, 2025, reporting record net sales of $124.1 million, a 30% increase year-over-year. The company also raised its 2025 net sales guidance, reflecting strong growth driven by strategic execution and advancements in its pipeline of novel, dropless platform technologies aimed at improving patient outcomes in chronic eye diseases.

The most recent analyst rating on (GKOS) stock is a Buy with a $131.00 price target. To see the full list of analyst forecasts on Glaukos stock, see the GKOS Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 21, 2025