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Glaukos (GKOS)
NYSE:GKOS
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Glaukos (GKOS) AI Stock Analysis

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GKOS

Glaukos

(NYSE:GKOS)

Rating:52Neutral
Price Target:
$92.00
▼(-3.28% Downside)
Glaukos' overall stock score reflects a mixed financial performance with strong revenue growth but ongoing profitability challenges. Technical indicators suggest a bearish trend, and valuation remains difficult due to negative earnings. Positive earnings call highlights and strategic corporate events provide some optimism, but risks from market headwinds and reimbursement changes remain significant.
Positive Factors
Market potential
Keratoconus is a vastly under-diagnosed condition with a sizable total addressable market, providing significant opportunity for Glaukos.
Reimbursement progress
NGS now establishing a professional fee schedule, leading to a more positive outlook on the ramp-up.
Revenue growth
The company's second-quarter sales exceeded expectations by 8%, driven by strong performance in the iDose segment.
Negative Factors
Competitive pressures
A slowdown in the OUS glaucoma segment is observed, attributed to ongoing competitive trialing.
Glaucoma segment challenges
The company is experiencing continued weakness from the U.S. glaucoma segment due to ongoing challenges.
Modest guidance increase
There are some notable headwinds implied in the more modest guidance increase including a Photrexa-to-Epioxa transition in 4Q25 that is likely to cause disruption.

Glaukos (GKOS) vs. SPDR S&P 500 ETF (SPY)

Glaukos Business Overview & Revenue Model

Company DescriptionGlaukos Corporation is a medical technology company focused on the development and commercialization of innovative surgical devices and therapies for the treatment of glaucoma and other diseases of the eye. Founded in 1998 and headquartered in San Clemente, California, Glaukos operates primarily in the ophthalmic sector, offering products such as the iStent and iStent inject, which are designed to reduce intraocular pressure in patients with glaucoma. The company is dedicated to enhancing patient outcomes through its minimally invasive surgical approaches, which aim to provide safer and more effective treatment options for eye care professionals and their patients.
How the Company Makes MoneyGlaukos generates revenue primarily through the sale of its surgical devices and related products for the treatment of glaucoma. The company's key revenue streams include the direct sales of its iStent and iStent inject devices, as well as revenue from related consumables and accessories. Glaukos also benefits from strategic partnerships with ophthalmology clinics and hospitals, which help to expand its market reach and distribution capabilities. Additionally, the company may explore partnerships with other healthcare organizations for product development, clinical studies, and co-marketing agreements, contributing to its overall revenue growth. As the prevalence of glaucoma and the demand for innovative treatment options increase, Glaukos is positioned to capitalize on these trends within the ophthalmic market.

Glaukos Earnings Call Summary

Earnings Call Date:Jul 30, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Oct 29, 2025
Earnings Call Sentiment Positive
The earnings call presented a strong performance with record sales and significant growth in key areas, particularly in the U.S. and international glaucoma franchises. However, there are notable challenges, including market turbulence from regulatory changes and proposed reimbursement reductions that could impact future growth. Overall, the highlights slightly outweigh the lowlights.
Q2-2025 Updates
Positive Updates
Record Second Quarter Consolidated Net Sales
Glaukos reported record second quarter consolidated net sales of $124.1 million, a 30% increase on a reported basis and 29% on a constant currency basis compared to the previous year.
U.S. Glaucoma Franchise Growth
The U.S. Glaucoma franchise delivered record second quarter net sales of $72.3 million, growing 45% year-over-year, driven by iDose TR which generated approximately $31 million in sales.
International Glaucoma Franchise Expansion
International net sales reached $31.3 million, marking a 20% year-over-year growth on a reported basis and 15% on a constant currency basis.
Epioxa NDA Review Progress
Important milestones were completed for Epioxa NDA review, with a PDUFA date set for October 20, 2025, potentially offering a breakthrough treatment for keratoconus patients.
Strong Financial Position
Excluding one-time investments, the company grew its cash and equivalents by more than $4 million in the second quarter.
Negative Updates
MIGS Market Headwind
The 5 MAC LCDs implemented are causing market turbulence, impacting the use of 2 MIGS surgical devices in the same procedures, expected to continue through 2025.
Corneal Health Franchise Challenges
The Corneal Health franchise saw modest growth of 4%, with anticipated disruption due to the transition from Photrexa to Epioxa.
Proposed CMS Reimbursement Reductions
CMS proposed reductions in physician fee reimbursement for certain ophthalmology procedures, which could impact economic incentives for comprehensive ophthalmologists.
Company Guidance
In the second quarter of 2025, Glaukos Corporation reported record consolidated net sales of $124.1 million, a 30% increase on a reported basis or 29% on a constant currency basis compared to the same quarter last year. This sales boost was primarily driven by the growing adoption and utilization of the iDose TR, which generated approximately $31 million in sales, contributing to a 45% year-over-year growth within the U.S. glaucoma franchise. As a result of this strong performance, Glaukos raised its full-year 2025 net sales guidance to a range of $480 million to $486 million, up from the previous range of $475 million to $485 million. The company's international glaucoma franchise also saw record net sales of $31.3 million, reflecting a 20% year-over-year growth on a reported basis and 15% on a constant currency basis. Furthermore, the Corneal Health franchise recorded net sales of $20.6 million, marking a 4% increase. Glaukos is advancing several clinical programs, including the Phase IIb/III clinical program for iDose TREX and the FDA's ongoing NDA review for Epioxa, with a PDUFA date set for October 20, 2025. The company also made strategic investments, including the acquisition of Mobius Therapeutics and purchasing a new building at its Aliso Viejo headquarters, while still managing to grow its cash and equivalents by over $4 million in the quarter.

Glaukos Financial Statement Overview

Summary
Glaukos shows strong revenue growth and a solid balance sheet with low leverage, which are positive indicators for stability. However, persistent losses and negative cash flows pose significant challenges, particularly in achieving profitability and enhancing cash flow generation. Continued focus on cost management and efficiency improvements is crucial for future financial health.
Income Statement
45
Neutral
Glaukos' income statement shows a consistent increase in revenue over the years, with a TTM revenue growth rate of 5.49%, indicating positive sales momentum. However, the company has struggled with profitability, reflected in negative EBIT and net profit margins. The TTM gross profit margin is healthy at 75.74%, but the persistent negative EBIT margin (-25.07%) and the negative net profit margin (-30.57%) highlight ongoing challenges in managing operational expenses and achieving profitability.
Balance Sheet
55
Neutral
The balance sheet of Glaukos displays a strong equity base with an equity ratio of 79.07%, indicating a solid foundation and low reliance on debt financing. The company maintains a manageable debt-to-equity ratio of 0.14, suggesting low financial risk from leverage. However, the negative return on equity (-16.19%) reflects the company's inability to generate positive returns for shareholders due to ongoing losses.
Cash Flow
40
Negative
Glaukos faces challenges with cash flow generation, as evidenced by negative free cash flow in recent periods. The TTM free cash flow growth rate shows improvement at 21.29%, but both operating cash flow to net income and free cash flow to net income ratios are negative, indicating issues in converting earnings into cash flow. This highlights potential liquidity concerns if the negative trend persists.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue404.52M383.48M314.71M282.86M294.01M224.96M
Gross Profit306.44M289.45M239.14M213.88M227.38M133.24M
EBITDA-83.53M-77.63M-82.12M-48.76M-1.47M-83.59M
Net Income-123.68M-146.37M-134.66M-99.19M-49.59M-120.35M
Balance Sheet
Total Assets966.18M974.76M940.41M1.00B1.05B1.01B
Cash, Cash Equivalents and Short-Term Investments298.70M318.92M295.43M352.69M414.05M404.37M
Total Debt105.48M103.40M383.74M382.48M382.38M270.81M
Total Liabilities202.22M207.82M478.65M472.38M462.55M338.05M
Stockholders Equity763.96M766.93M461.77M530.00M587.15M667.45M
Cash Flow
Free Cash Flow-53.24M-67.62M-78.01M-63.35M-23.08M-29.92M
Operating Cash Flow-45.97M-61.32M-57.76M-33.08M24.71M-22.99M
Investing Cash Flow40.27M47.83M14.10M44.78M-58.23M-205.06M
Financing Cash Flow80.32M91.54M15.04M6.25M39.26M262.54M

Glaukos Technical Analysis

Technical Analysis Sentiment
Positive
Last Price95.12
Price Trends
50DMA
95.70
Negative
100DMA
94.14
Positive
200DMA
114.93
Negative
Market Momentum
MACD
-0.33
Negative
RSI
56.47
Neutral
STOCH
73.87
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GKOS, the sentiment is Positive. The current price of 95.12 is above the 20-day moving average (MA) of 89.70, below the 50-day MA of 95.70, and below the 200-day MA of 114.93, indicating a neutral trend. The MACD of -0.33 indicates Negative momentum. The RSI at 56.47 is Neutral, neither overbought nor oversold. The STOCH value of 73.87 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GKOS.

Glaukos Risk Analysis

Glaukos disclosed 25 risk factors in its most recent earnings report. Glaukos reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Glaukos Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
66
Neutral
$5.40B-91.13%22.37%31.14%
65
Neutral
$3.80B47.735.15%7.21%-23.29%
61
Neutral
$3.09B30.62-17.87%8.57%-1154.64%
58
Neutral
$2.71B53.478.07%22.05%785.52%
53
Neutral
$2.25B-26.40%55.71%24.37%
52
Neutral
$5.38B-12.98%26.70%48.19%
51
Neutral
$7.83B-0.18-40.10%2.29%21.46%-2.03%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GKOS
Glaukos
95.12
-37.47
-28.26%
ITGR
Integer Holdings
107.38
-21.07
-16.40%
LIVN
LivaNova
55.45
5.21
10.37%
IRTC
Irhythm Technologies
169.79
97.37
134.45%
INSP
Inspire Medical Systems
92.30
-91.14
-49.68%
PRCT
PROCEPT BioRobotics
40.34
-38.35
-48.74%

Glaukos Corporate Events

Product-Related AnnouncementsBusiness Operations and Strategy
Glaukos Highlights Innovation in Recent Investor Presentation
Positive
Aug 12, 2025

Glaukos Corporation’s recent investor presentation highlights its strategic focus on innovation and commercial excellence, aiming to improve standards of care in ophthalmology. The company is advancing its iDose TR therapy, a groundbreaking sustained-release drug delivery system for glaucoma, which is expected to enhance patient compliance and outcomes by reducing reliance on traditional topical medications.

Business Operations and StrategyFinancial Disclosures
Glaukos Reports Record Q2 Sales, Raises 2025 Guidance
Positive
Jul 30, 2025

On July 30, 2025, Glaukos Corporation announced its financial results for the second quarter ended June 30, 2025, reporting record net sales of $124.1 million, a 30% increase year-over-year. The company also raised its 2025 net sales guidance, reflecting strong growth driven by strategic execution and advancements in its pipeline of novel, dropless platform technologies aimed at improving patient outcomes in chronic eye diseases.

Executive/Board ChangesShareholder Meetings
Glaukos Stockholders Approve Key Proposals at Annual Meeting
Positive
Jun 3, 2025

On May 29, 2025, Glaukos Corporation held its annual meeting of stockholders, where three key proposals were voted on. The election of three Class I directors, approval of executive compensation, and ratification of Ernst & Young LLP as the independent auditor for 2025 were all passed, reflecting strong shareholder support and setting the stage for continued corporate governance and financial oversight.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 26, 2025