Gh Research Plc (GHRS)
NASDAQ:GHRS
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GH Research
(NASDAQ:GHRS)
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Rating:54Neutral
Price Target:
$25.00
▲(36.31% Upside)
Action:Reiterated
Date:05/16/26
The score is held down primarily by weak financial performance—no revenue, widening losses, and sustained cash burn—despite a strong low-debt balance sheet. Technicals are supportive with price above key moving averages and positive momentum, but valuation remains challenged due to losses (negative P/E) and no dividend data.
Positive Factors
Low leverage with substantial equity
GH Research's extremely low leverage and sizable equity base provide structural financial resilience for a clinical-stage biotech. This reduces insolvency risk during multi-year pivotal programs, supports R&D spending without large interest burdens, and improves flexibility to execute clinical plans.
Negative Factors
No product revenue and widening losses
GH Research remains pre-revenue with escalating net losses, reflecting higher R&D and G&A as programs scale. Without commercial sales, recurring losses will continue to pressure equity and require external funding, making long-term sustainability contingent on successful late-stage outcomes or partner deals.
Read all positive and negative factors
Positive Factors
Negative Factors
Low leverage with substantial equity
GH Research's extremely low leverage and sizable equity base provide structural financial resilience for a clinical-stage biotech. This reduces insolvency risk during multi-year pivotal programs, supports R&D spending without large interest burdens, and improves flexibility to execute clinical plans.
Read all positive factors
GH Research (GHRS) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$1.47B
Dividend YieldN/A
Average Volume (3M)235.59K
Price to Earnings (P/E)―
Beta (1Y)1.22
Revenue GrowthN/A
EPS Growth-15.44%
CountryUS
Employees50
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-0.92
Shares Outstanding68,557,175
10 Day Avg. Volume278,972
30 Day Avg. Volume235,590
Financial Highlights & Ratios
PEG Ratio-3.01
Price to Book (P/B)2.77
Price to Sales (P/S)0.00
P/FCF Ratio-17.75
Enterprise Value/Market Cap0.95
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit-4.01K
Enterprise Value/Ebitda-24.02
Forecast
1Y Price Target
$40.57Price Target Upside121.22% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering8
EPS Forecast (FY)-1.41
Revenue Forecast (FY)N/A
GH Research Business Overview & Revenue Model
Company Description
GH Research PLC is a clinical-stage biopharmaceutical firm dedicated to creating novel therapies for psychiatric and neurological conditions. The company primarily concentrates on developing 5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT) treatments,...
How the Company Makes Money
As a clinical-stage biopharmaceutical company, GH Research does not have publicly disclosed recurring revenue from product sales. The company’s operations are primarily funded through external financing, including proceeds from equity offerings (s...
GH Research Financial Statement Overview
Summary
Income Statement
18
Very Negative
Balance Sheet
72
Positive
Cash Flow
33
Negative
| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Gross Profit | -350.00K | -335.00K | 0.00 | 0.00 | 0.00 | 0.00 |
| EBITDA | -58.38M | -60.34M | -38.60M | -35.21M | -22.41M | -9.17M |
| Net Income | -56.41M | -48.26M | -38.96M | -35.59M | -22.46M | -9.20M |
Balance Sheet | ||||||
| Total Assets | 275.27M | 288.23M | 188.27M | 226.30M | 254.36M | 279.92M |
| Cash, Cash Equivalents and Short-Term Investments | 267.32M | 280.71M | 149.32M | 161.56M | 165.96M | 276.78M |
| Total Debt | 432.00K | 512.00K | 624.00K | 974.00K | 0.00 | 0.00 |
| Total Liabilities | 11.89M | 8.53M | 9.32M | 7.33M | 4.55M | 2.75M |
| Stockholders Equity | 263.38M | 279.70M | 178.95M | 218.97M | 249.82M | 277.18M |
Cash Flow | ||||||
| Free Cash Flow | -46.51M | -43.67M | -42.33M | -33.44M | -26.27M | -15.39M |
| Operating Cash Flow | -46.33M | -43.55M | -42.28M | -33.34M | -26.20M | -15.28M |
| Investing Cash Flow | 43.35M | 46.17M | 65.14M | -54.10M | -84.69M | -104.00K |
| Financing Cash Flow | -2.23M | 139.65M | -304.00K | -204.00K | 0.00 | 286.45M |
GH Research Technical Analysis
Neutral
18.34
Price Trends
19.65
Positive
17.58
Positive
15.63
Positive
Market Momentum
0.98
Positive
47.47
Neutral
34.82
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GHRS, the sentiment is Neutral. The current price of 18.34 is below the 20-day moving average (MA) of 22.52, below the 50-day MA of 19.65, and above the 200-day MA of 15.63, indicating a neutral trend. The MACD of 0.98 indicates Positive momentum. The RSI at 47.47 is Neutral, neither overbought nor oversold. The STOCH value of 34.82 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for GHRS.
GH Research Risk Analysis
GH Research disclosed 104 risk factors in its most recent earnings report. GH Research reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
GH Research Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
56 Neutral | $2.95B | -8.92 | -43.94% | ― | 39.04% | 29.88% | |
56 Neutral | $1.58B | -15.53 | -56.07% | ― | 3.42% | -11.04% | |
56 Neutral | $909.71M | 76.73 | 4.75% | ― | 15.66% | ― | |
54 Neutral | $1.47B | -23.57 | -19.83% | ― | ― | -15.44% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
43 Neutral | $745.82M | -3.07 | -161.87% | ― | ― | -6.15% | |
42 Neutral | $552.69M | -2.73 | -188.82% | ― | 4.89% | 24.20% |
* Healthcare Sector Average
GHRS
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GH Research Corporate Events
GH Research to Present New GH001 Phase 2b Data in Treatment-Resistant Depression at ASCP 2026
May 21, 2026
GH Research PLC will showcase new Phase 2b data on its inhaled psychedelic-based depression therapy GH001 at the American Society of Clinical Psychopharmacology annual meeting in Miami from May 26–29, 2026. The presentations underline the co...
GH Research Launches $200 Million At-the-Market Share Offering With Stifel
May 14, 2026
On May 14, 2026, GH Research PLC entered into an at-the-market equity offering sales agreement with Stifel, Nicolaus Company to sell up to $200 million of its ordinary shares from time to time. The shares are registered under an existing Form F-3...
GH Research Posts Wider Q1 2026 Loss as R&D and Admin Costs Rise
May 14, 2026
On May 14, 2026, GH Research PLC filed a Form 6-K in the United States reporting its first-quarter 2026 results and providing business updates, alongside posting an updated investor presentation. The filing also furnished unaudited condensed conso...
GH Research Sets June 25, 2026 AGM and Tables Board, Auditor Votes
May 13, 2026
GH Research has called its 2026 annual general meeting for June 25, 2026, in Dublin, inviting shareholders of record as of May 1, 2026 to attend, vote and review the company’s 2025 Irish statutory financial statements. The company has circul...
GH Research to Attend APA Annual Meeting in San Francisco in May 2026
May 13, 2026
GH Research PLC announced on May 13, 2026, that it will attend the American Psychiatric Association Annual Meeting in San Francisco, California. The conference is scheduled to take place from May 16 to May 20, 2026, and the company’s partici...
GH Research Raises $111 Million in Completed Share Offering to Fund Depression Pipeline
Apr 30, 2026
On April 30, 2026, GH Research PLC completed an underwritten public offering of 6,527,779 ordinary shares at $18.00 per share, raising estimated net proceeds of about $111.2 million after fees. The transaction, priced a day earlier and led by Stif...
GH Research Publishes Phase 2b GH001 TRD Data and Highlights Severity-Independent Efficacy
Mar 25, 2026
On March 25, 2026, GH Research PLC reported that full results from its randomized, double-blind, placebo-controlled Phase 2b trial of mebufotenin (GH001) in treatment-resistant depression have been published and peer-reviewed in JAMA Psychiatry. T...
GH Research to Join Stifel 2026 Virtual CNS Forum Fireside Chat
Mar 16, 2026
On March 16, 2026, GH Research PLC reported that it will take part in a fireside chat at the Stifel 2026 Virtual CNS Forum, a sector-focused event scheduled to be held online from March 17 to 18, 2026. The planned participation underscores the com...
GH Research Posts 2025 Results as TRD Drug GH001 Clears Key Phase 2b Milestone
Mar 5, 2026
GH Research PLC reported on March 5, 2026, that it completed a successful Phase 2b trial of its inhaled mebufotenin candidate GH001 in treatment-resistant depression in 2025, demonstrating rapid and durable remission rates with a strong safety pro...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.