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GH Research (GHRS)
NASDAQ:GHRS
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GH Research (GHRS) AI Stock Analysis

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GHRS

GH Research

(NASDAQ:GHRS)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$19.00
▲(3.60% Upside)
Action:ReiteratedDate:04/23/26
The score is held back primarily by weak financial performance (no revenue, widening losses, and ongoing cash burn), partly offset by a strong, low-leverage balance sheet. Technicals are supportive with clear upward trend and positive momentum, while valuation remains a drag due to negative earnings and no dividend.
Positive Factors
Strong balance sheet and low leverage
Very low debt and ~ $280M of equity/cash provide durable financial flexibility to fund pivotal programs and device development. This reduces near-term solvency risk, limits immediate refinancing pressure, and supports execution of multi-stage clinical plans without immediate commercial revenue.
Negative Factors
Pre-revenue with widening operating losses
Persistent pre-revenue status combined with accelerating net and operating losses means the company must rely on external funding until commercialization. Over months this raises dilution and execution risk, pressuring management to prioritize spend and potentially slow non-core investments.
Read all positive and negative factors
Positive Factors
Negative Factors
Strong balance sheet and low leverage
Very low debt and ~ $280M of equity/cash provide durable financial flexibility to fund pivotal programs and device development. This reduces near-term solvency risk, limits immediate refinancing pressure, and supports execution of multi-stage clinical plans without immediate commercial revenue.
Read all positive factors

GH Research (GHRS) vs. SPDR S&P 500 ETF (SPY)

GH Research Business Overview & Revenue Model

Company Description
GH Research PLC, a clinical-stage biopharmaceutical company, engages in developing various therapies for the treatment of psychiatric and neurological disorders. The company focuses on developing 5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT) therap...
How the Company Makes Money
As a clinical-stage biopharmaceutical company, GH Research does not have publicly disclosed recurring revenue from product sales. The company’s operations are primarily funded through external financing, including proceeds from equity offerings (s...

GH Research Financial Statement Overview

Summary
Overall financials reflect an early-stage biotech profile: strong balance sheet (very low debt and sizable equity) offsets weak operating fundamentals. The company is pre-revenue with widening losses (net loss and EBIT deteriorating through TTM) and persistent cash burn, with operating and free cash flow both deeply negative in TTM.
Income Statement
18
Very Negative
Balance Sheet
72
Positive
Cash Flow
30
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit-335.00K0.000.000.000.00
EBITDA-60.34M-38.60M-35.21M-22.41M-9.17M
Net Income-48.26M-38.96M-35.59M-22.46M-9.20M
Balance Sheet
Total Assets288.23M188.27M226.30M254.36M279.92M
Cash, Cash Equivalents and Short-Term Investments280.71M149.32M161.56M165.96M276.78M
Total Debt512.00K624.00K974.00K0.000.00
Total Liabilities8.53M9.32M7.33M4.55M2.75M
Stockholders Equity279.70M178.95M218.97M249.82M277.18M
Cash Flow
Free Cash Flow-43.67M-42.33M-33.44M-26.27M-15.39M
Operating Cash Flow-43.55M-42.28M-33.34M-26.20M-15.28M
Investing Cash Flow46.17M65.14M-54.10M-84.69M-104.00K
Financing Cash Flow139.65M-304.00K-204.00K0.00286.45M

GH Research Technical Analysis

Technical Analysis Sentiment
Positive
Last Price18.34
Price Trends
50DMA
15.21
Positive
100DMA
14.96
Positive
200DMA
14.41
Positive
Market Momentum
MACD
0.69
Negative
RSI
72.21
Negative
STOCH
91.79
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GHRS, the sentiment is Positive. The current price of 18.34 is above the 20-day moving average (MA) of 14.99, above the 50-day MA of 15.21, and above the 200-day MA of 14.41, indicating a bullish trend. The MACD of 0.69 indicates Negative momentum. The RSI at 72.21 is Negative, neither overbought nor oversold. The STOCH value of 91.79 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GHRS.

GH Research Risk Analysis

GH Research disclosed 104 risk factors in its most recent earnings report. GH Research reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

GH Research Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
$1.84B-16.13-56.64%-36.36%-945.72%
56
Neutral
$2.70B-5.25-43.17%-16.50%33.02%
56
Neutral
$1.20B440.781.15%26.54%
52
Neutral
$1.17B-16.06-16.30%8.16%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$693.32M-2.57-178.61%647.13%26.79%
44
Neutral
$918.02M-4.22-141.99%31.16%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GHRS
GH Research
18.81
9.31
98.00%
RLAY
Relay Therapeutics
15.09
11.90
373.04%
TSHA
Taysha Gene Therapies
6.40
4.58
251.65%
SANA
Sana Biotechnology
3.44
1.67
94.35%
PHAR
Pharming Group
16.64
8.06
93.94%
PRME
Prime Medicine, Inc.
3.84
2.09
119.43%

GH Research Corporate Events

GH Research Publishes Phase 2b GH001 TRD Data and Highlights Severity-Independent Efficacy
Mar 25, 2026
On March 25, 2026, GH Research PLC reported that full results from its randomized, double-blind, placebo-controlled Phase 2b trial of mebufotenin (GH001) in treatment-resistant depression have been published and peer-reviewed in JAMA Psychiatry. T...
GH Research to Join Stifel 2026 Virtual CNS Forum Fireside Chat
Mar 16, 2026
On March 16, 2026, GH Research PLC reported that it will take part in a fireside chat at the Stifel 2026 Virtual CNS Forum, a sector-focused event scheduled to be held online from March 17 to 18, 2026. The planned participation underscores the com...
GH Research Posts 2025 Results as TRD Drug GH001 Clears Key Phase 2b Milestone
Mar 5, 2026
GH Research PLC reported on March 5, 2026, that it completed a successful Phase 2b trial of its inhaled mebufotenin candidate GH001 in treatment-resistant depression in 2025, demonstrating rapid and durable remission rates with a strong safety pro...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 23, 2026