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Gain Therapeutics, Inc. (GANX)
NASDAQ:GANX
US Market
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Gain Therapeutics (GANX) AI Stock Analysis

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GANX

Gain Therapeutics

(NASDAQ:GANX)

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Neutral 46 (OpenAI - 5.2)
Rating:46Neutral
Price Target:
$2.00
▼(-6.54% Downside)
Action:ReiteratedDate:03/27/26
The score is primarily constrained by weak financial performance (pre-revenue, ongoing losses and cash burn) and bearish technical conditions (below major moving averages with negative MACD). Positive Phase 1b Parkinson’s data and pipeline progress provide an offsetting upside catalyst, while valuation remains difficult to assess due to negative earnings and no dividend.
Positive Factors
Proprietary discovery platform & focused GBA1 pipeline
The proprietary computational platform and a focused GBA1-directed pipeline create durable R&D leverage: a scalable discovery engine can accelerate lead identification, support multiple chemistry series (e.g., GT‑04686 preclinical series), and increase chances of producing clinic-ready assets and licensing or partnership opportunities over the next 2–6 months and beyond.
Negative Factors
Pre‑revenue business model
Being pre‑revenue is a durable fundamental constraint: the company relies on external financing to fund operations and trials until commercialization, meaning long lead times to cash generation. This elevates dilution and execution risk if clinical programs face delays or fail to achieve regulatory approvals necessary to generate sustainable revenue.
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Positive Factors
Negative Factors
Proprietary discovery platform & focused GBA1 pipeline
The proprietary computational platform and a focused GBA1-directed pipeline create durable R&D leverage: a scalable discovery engine can accelerate lead identification, support multiple chemistry series (e.g., GT‑04686 preclinical series), and increase chances of producing clinic-ready assets and licensing or partnership opportunities over the next 2–6 months and beyond.
Read all positive factors

Gain Therapeutics (GANX) vs. SPDR S&P 500 ETF (SPY)

Gain Therapeutics Business Overview & Revenue Model

Company Description
Gain Therapeutics, Inc., a biotechnology company, engages in developing various therapies to treat diseases caused by protein misfolding. It focuses on rare genetic diseases and neurological disorders. The company uses its Site-Directed Enzyme Enh...
How the Company Makes Money
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Gain Therapeutics Financial Statement Overview

Summary
Financials reflect an early-stage biotech profile: essentially no revenue, persistent and sizable losses, and historically material cash burn. The balance sheet is a relative strength with low leverage and improved assets/equity in 2025, but negative returns and weak cash flow quality keep overall financial performance below average.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.0055.18K132.64K133.93K
Gross Profit-94.05K0.0055.18K-8.11M-7.03M
EBITDA-18.62M-20.27M-22.17M-17.76M-13.82M
Net Income-20.16M-20.41M-22.27M-17.59M-13.89M
Balance Sheet
Total Assets22.82M12.12M18.61M24.10M38.99M
Cash, Cash Equivalents and Short-Term Investments20.84M10.39M16.79M20.14M36.88M
Total Debt732.07K653.01K1.03M1.27M1.61M
Total Liabilities4.25M4.78M6.03M5.22M4.17M
Stockholders Equity18.56M7.34M12.58M18.88M34.82M
Cash Flow
Free Cash Flow-18.47M-18.90M-18.88M-14.81M-12.46M
Operating Cash Flow-18.47M-18.87M-18.87M-14.69M-12.37M
Investing Cash Flow0.004.98M10.22M-14.77M-94.21K
Financing Cash Flow28.45M13.01M12.64M-78.77K41.77M

Gain Therapeutics Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price2.14
Price Trends
50DMA
2.12
Negative
100DMA
2.48
Negative
200DMA
2.16
Negative
Market Momentum
MACD
-0.07
Negative
RSI
51.03
Neutral
STOCH
76.42
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GANX, the sentiment is Neutral. The current price of 2.14 is above the 20-day moving average (MA) of 1.90, above the 50-day MA of 2.12, and below the 200-day MA of 2.16, indicating a neutral trend. The MACD of -0.07 indicates Negative momentum. The RSI at 51.03 is Neutral, neither overbought nor oversold. The STOCH value of 76.42 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for GANX.

Gain Therapeutics Risk Analysis

Gain Therapeutics disclosed 63 risk factors in its most recent earnings report. Gain Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Gain Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
$347.77M-2.24-129.98%250.00%15.15%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$75.19M-0.84-59.07%-58.47%
46
Neutral
$90.40M-237.54%42.29%
45
Neutral
$33.33M-3.48-88.89%56.52%75.22%
40
Underperform
$38.77M-1.74774.80%-8.16%22.44%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GANX
Gain Therapeutics
2.05
0.25
13.89%
PSTV
Plus Therapeutics
5.95
-10.52
-63.86%
ABVC
ABVC BioPharma
1.23
0.37
43.02%
PMVP
PMV Pharmaceuticals
1.37
0.35
34.31%
PRLD
Prelude Therapeutics
4.43
3.62
446.91%
IMMX
Immix Biopharma
9.96
8.32
507.32%

Gain Therapeutics Corporate Events

Business Operations and StrategyProduct-Related Announcements
Gain Therapeutics Reports Promising GT-02287 Parkinson’s Data
Positive
Mar 18, 2026
On March 18, 2026, Gain Therapeutics reported new clinical and biomarker results from its Phase 1b study of GT-02287 in Parkinson’s disease, presented in an oral session at the AD/PD 2026 conference in Copenhagen. Data from Part 1 and the on...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 27, 2026