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Gain Therapeutics, Inc. (GANX)
NASDAQ:GANX
US Market
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Gain Therapeutics (GANX) AI Stock Analysis

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GANX

Gain Therapeutics

(NASDAQ:GANX)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$2.00
▼(-6.10% Downside)
Action:Reiterated
Date:05/29/26
The score is held back primarily by weak financial performance (pre-revenue, large ongoing losses and cash burn, and declining equity), which elevates financing risk. Offsetting this, corporate updates around GT-02287 were positive and technicals show improving near-term momentum, though the longer-term trend remains weaker and valuation is constrained by negative earnings.
Positive Factors
Clinical data: GT-02287 safety & retention
Robust safety/tolerability and very high participant retention in the Phase 1b extension reduce clinical development risk and preserve trial continuity. Durable safety and adherence improve chances of moving into later trials and attract partners or financers over the medium term.
Negative Factors
Persistent negative cash flow
Significant, ongoing operating and free cash outflows indicate the company is burning cash at scale. This steady burn creates a continuous need for external funding, raising dilution and execution risk if financing markets tighten or development timelines extend beyond current runway.
Read all positive and negative factors
Positive Factors
Negative Factors
Clinical data: GT-02287 safety & retention
Robust safety/tolerability and very high participant retention in the Phase 1b extension reduce clinical development risk and preserve trial continuity. Durable safety and adherence improve chances of moving into later trials and attract partners or financers over the medium term.
Read all positive factors

Gain Therapeutics (GANX) vs. SPDR S&P 500 ETF (SPY)

Gain Therapeutics Business Overview & Revenue Model

Company Description
Gain Therapeutics, Inc., a biotechnology company, engages in developing various therapies to treat diseases caused by protein misfolding. It focuses on rare genetic diseases and neurological disorders. The company uses its Site-Directed Enzyme Enh...
How the Company Makes Money
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Gain Therapeutics Financial Statement Overview

Summary
Pre-revenue profile with persistent, sizeable losses (TTM net loss ~-$21.2M) and heavy cash burn (TTM operating/free cash flow ~-$19.4M). Balance-sheet leverage is low (TTM debt ~ $0.3M; minimal debt-to-equity), but equity has declined (to ~ $14.0M TTM), implying continued dependence on external financing.
Income Statement
12
Very Negative
Balance Sheet
58
Neutral
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.0055.18K140.11K164.99K
Gross Profit0.000.000.0055.18K140.11K164.99K
EBITDA-19.60M-18.62M-20.27M-22.17M-17.71M-13.81M
Net Income-21.24M-20.16M-20.41M-22.27M-17.59M-13.89M
Balance Sheet
Total Assets18.74M22.82M12.12M18.61M24.10M38.99M
Cash, Cash Equivalents and Short-Term Investments16.54M20.84M10.39M16.79M20.14M36.88M
Total Debt298.76K732.07K653.01K1.03M1.27M1.61M
Total Liabilities4.73M4.25M4.78M6.03M5.22M4.17M
Stockholders Equity14.01M18.56M7.34M12.58M18.88M34.82M
Cash Flow
Free Cash Flow-19.37M-18.47M-18.90M-18.88M-14.81M-12.46M
Operating Cash Flow-19.37M-18.47M-18.87M-18.87M-14.69M-12.37M
Investing Cash Flow0.000.004.98M10.22M-14.77M-94.21K
Financing Cash Flow26.46M28.45M13.01M12.64M-78.77K41.77M

Gain Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2.13
Price Trends
50DMA
1.88
Positive
100DMA
2.03
Negative
200DMA
2.20
Negative
Market Momentum
MACD
-0.02
Negative
RSI
55.49
Neutral
STOCH
77.38
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GANX, the sentiment is Positive. The current price of 2.13 is above the 20-day moving average (MA) of 1.81, above the 50-day MA of 1.88, and below the 200-day MA of 2.20, indicating a neutral trend. The MACD of -0.02 indicates Negative momentum. The RSI at 55.49 is Neutral, neither overbought nor oversold. The STOCH value of 77.38 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GANX.

Gain Therapeutics Risk Analysis

Gain Therapeutics disclosed 9 risk factors in its most recent earnings report. Gain Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Gain Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$83.18M-3.88-201.43%33.86%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$312.21M-4.16-118.24%138.86%42.14%
49
Neutral
$40.06M-3.24-198.48%-0.46%96.28%
46
Neutral
$36.66M-3.81-70.28%-100.00%-170.04%
42
Neutral
$64.00M-0.82-68.98%-26.14%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GANX
Gain Therapeutics
1.95
0.02
1.04%
PSTV
Plus Therapeutics
5.82
-3.37
-36.68%
ABVC
ABVC BioPharma
1.41
-0.13
-8.44%
PMVP
PMV Pharmaceuticals
1.20
0.32
36.36%
PRLD
Prelude Therapeutics
3.92
3.01
330.77%
IMMX
Immix Biopharma
9.00
6.40
246.15%

Gain Therapeutics Corporate Events

Business Operations and StrategyProduct-Related Announcements
Gain Therapeutics Reports Interim Data for Parkinson’s Candidate
Positive
May 26, 2026
On May 26, 2026, Gain Therapeutics reported interim clinical and biomarker data from the nine‑month extension (Part 2) of its Phase 1b open‑label study of GT‑02287 in Parkinson’s disease patients, following an oral presenta...
Business Operations and StrategyProduct-Related Announcements
Gain Therapeutics Reports Promising GT-02287 Parkinson’s Data
Positive
Mar 18, 2026
On March 18, 2026, Gain Therapeutics reported new clinical and biomarker results from its Phase 1b study of GT-02287 in Parkinson’s disease, presented in an oral session at the AD/PD 2026 conference in Copenhagen. Data from Part 1 and the on...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 29, 2026