Clinical Trial ProgressThe P1b trial completed enrollment above the 15-patient target and received approval to extend dosing for up to 12 months, allowing for longer treatment assessment.
Drug EfficacyGT-02287 shows potential in reducing toxic alpha-synuclein levels, which are linked to neurodegenerative diseases like Parkinson's.
Safety ProfileGT-02287 was generally well tolerated, with no treatment-emergent serious adverse events and no protocol changes recommended after two independent data monitoring committee reviews.