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Establishment Labs Holdings Inc (ESTA)
NASDAQ:ESTA

Establishment Labs Holdings (ESTA) AI Stock Analysis

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ESTA

Establishment Labs Holdings

(NASDAQ:ESTA)

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Neutral 67 (OpenAI - 5.2)
Rating:67Neutral
Price Target:
$60.00
▲(8.48% Upside)
Action:ReiteratedDate:02/25/26
The score is driven primarily by strong technical momentum and a constructive earnings outlook (accelerating growth, margin expansion, and a stated path to positive EBITDA and improved cash flow). Offsetting this, financial performance is still constrained by ongoing losses and a history of significant cash burn, and valuation is weaker due to the negative P/E and lack of dividend support.
Positive Factors
Sustained revenue scaling
Meaningful multi-year revenue growth and a re-acceleration in 2025 reflect durable commercial adoption of Motiva and related products. Persistent top-line expansion supports operating leverage, larger addressable share, and better resource allocation for sales, manufacturing and clinical investments over the next 2–6 months.
Negative Factors
Historic cash burn
Prior multi-year negative operating and free cash flow demonstrate the business historically required external funding to grow. Even with 2025 improvement to 0 OCF in reported data, the company must sustain positive cash generation across cycles to insure against execution slippage, making near-term cash conversion a structural risk.
Read all positive and negative factors
Positive Factors
Negative Factors
Sustained revenue scaling
Meaningful multi-year revenue growth and a re-acceleration in 2025 reflect durable commercial adoption of Motiva and related products. Persistent top-line expansion supports operating leverage, larger addressable share, and better resource allocation for sales, manufacturing and clinical investments over the next 2–6 months.
Read all positive factors

Establishment Labs Holdings (ESTA) vs. SPDR S&P 500 ETF (SPY)

Establishment Labs Holdings Business Overview & Revenue Model

Company Description
Establishment Labs Holdings Inc., a medical technology company, manufactures and markets medical devices for aesthetic and reconstructive plastic surgery. The company primarily offers silicone gel-filled breast implants under Motiva Implants brand...
How the Company Makes Money
Establishment Labs makes money primarily by selling breast implants and related surgical/aesthetic products to customers in the healthcare channel (e.g., hospitals, clinics, and surgeons) across the geographies where it is approved to market and d...

Establishment Labs Holdings Earnings Call Summary

Earnings Call Date:Feb 24, 2026
(Q4-2025)
|
% Change Since: |
Next Earnings Date:May 11, 2026
Earnings Call Sentiment Positive
The call presents strong positive momentum: robust revenue growth (Q4 +45.2%, FY +27.2%), expanding U.S. adoption and materially improved margins and adjusted EBITDA. Management provided constructive 2026 guidance (≈25% growth) and a path to full-year cash flow profitability in 2027, supported by product momentum (Motiva, Preserve, Mia) and a growing account base. Notable risks include China/distributor volatility, a reconstruction revenue cadence pushed to 2027, elevated operating expenses and refinancing considerations, and execution risk tied to rapid commercial expansion and a leadership transition. Overall, the positive operational and financial trends materially outweigh the listed challenges.
Positive Updates
Strong Quarterly and Full-Year Revenue Growth
Q4 2025 revenue $64.6M, up 45.2% year-over-year; total 2025 revenue $211.1M, up 27.2% versus 2024.
Negative Updates
China and Distributor Market Volatility
China experienced challenges in the period and remains a management focus; distributor markets exhibit timing-related ebbs and flows that can produce quarter-to-quarter volatility in reported sales.
Read all updates
Q4-2025 Updates
Negative
Strong Quarterly and Full-Year Revenue Growth
Q4 2025 revenue $64.6M, up 45.2% year-over-year; total 2025 revenue $211.1M, up 27.2% versus 2024.
Read all positive updates
Company Guidance
Management guided 2026 revenue of $264–266 million (a 25.1%–26.0% increase versus 2025’s $211.1M), with OUS growth in the single digits and the U.S. rising to >30% of sales (vs. ~22% in 2025); they expect gross margins to expand 200–300 basis points (Q4 2025 gross margin was 70.5% and 2025 margins improved ~330 bps YoY), operating expenses of approximately $195–200 million (cash operating spend ~ $175–180M excluding non‑cash items), adjusted EBITDA to be positive every quarter in 2026, and free cash use to be less than half of 2025 with the company reaching cash‑flow positive in 2026 without additional equity (supported by $75.6M year‑end cash). Management also cited product metrics and investments: global minimally invasive demand >$30M in 2026, Preserve ASPs roughly 2x traditional augmentation (average U.S. augmentation ~$9K today), plan to add up to 15 U.S. sales reps (majority already hired), train ≥200 surgeons on Preserve by year‑end, and view reconstruction as a key 2027 growth driver.

Establishment Labs Holdings Financial Statement Overview

Summary
Revenue has scaled strongly with improving gross margins, and leverage risk improved materially in 2025 as debt fell. However, profitability is still negative and historical operating/free cash flow has been deeply negative, with 2025 not yet demonstrating sustained positive cash generation.
Income Statement
46
Neutral
Balance Sheet
62
Positive
Cash Flow
18
Very Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue211.08M166.03M165.15M161.70M126.68M
Gross Profit146.31M109.53M106.98M106.59M85.40M
EBITDA-32.77M-56.22M-58.31M-56.90M-26.54M
Net Income-51.06M-84.60M-78.50M-75.21M-41.14M
Balance Sheet
Total Assets357.17M346.83M268.64M211.06M139.53M
Cash, Cash Equivalents and Short-Term Investments75.57M90.35M40.03M66.36M53.41M
Total Debt264.47M225.29M192.22M179.35M54.21M
Total Liabilities333.62M293.74M250.25M219.25M88.79M
Stockholders Equity23.55M53.09M18.39M-8.19M50.74M
Cash Flow
Free Cash Flow-56.94M-74.08M-113.06M-86.43M-34.26M
Operating Cash Flow-50.89M-58.52M-88.51M-52.17M-27.53M
Investing Cash Flow-7.03M-15.61M-24.55M-34.79M-7.16M
Financing Cash Flow40.43M125.89M86.23M100.25M4.05M

Establishment Labs Holdings Technical Analysis

Technical Analysis Sentiment
Negative
Last Price55.31
Price Trends
50DMA
68.80
Negative
100DMA
68.69
Negative
200DMA
55.16
Positive
Market Momentum
MACD
-3.59
Positive
RSI
26.19
Positive
STOCH
27.42
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ESTA, the sentiment is Negative. The current price of 55.31 is below the 20-day moving average (MA) of 65.17, below the 50-day MA of 68.80, and above the 200-day MA of 55.16, indicating a neutral trend. The MACD of -3.59 indicates Positive momentum. The RSI at 26.19 is Positive, neither overbought nor oversold. The STOCH value of 27.42 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ESTA.

Establishment Labs Holdings Risk Analysis

Establishment Labs Holdings disclosed 66 risk factors in its most recent earnings report. Establishment Labs Holdings reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Establishment Labs Holdings Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$849.01M10.1214.52%-13.98%15.94%
67
Neutral
$1.62B-42.28-201.79%24.76%-10.41%
65
Neutral
$743.40M21.814.97%1.58%
59
Neutral
$1.69B211.682.44%9.81%-1067.00%
56
Neutral
$1.07B26.784.68%2.02%4.69%-51.57%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$954.29M-88.99-30.23%159.43%67.42%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ESTA
Establishment Labs Holdings
55.31
14.88
36.80%
CNMD
Conmed
34.58
-23.83
-40.80%
AORT
Artivion
35.29
11.04
45.53%
INMD
InMode
13.40
-4.30
-24.29%
SSII
SS Innovations International
4.91
-4.34
-46.92%
BVS
Bioventus
8.94
-0.09
-1.00%

Establishment Labs Holdings Corporate Events

Financial DisclosuresRegulatory Filings and Compliance
Establishment Labs Shares Preliminary Data at Healthcare Conference
Neutral
Jan 14, 2026
On January 14, 2026, Establishment Labs presented at the J.P. Morgan Healthcare Conference, where it shared presentation materials with investors and stakeholders, later furnishing these materials in a Form 8-K filing. The company emphasized that ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 25, 2026