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Artivion (AORT)
NYSE:AORT

Artivion (AORT) AI Stock Analysis

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AORT

Artivion

(NYSE:AORT)

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Neutral 59 (OpenAI - 5.2)
Rating:59Neutral
Price Target:
$42.00
▲(12.33% Upside)
Action:ReiteratedDate:02/14/26
The score is driven primarily by improving financial performance and a strong, margin-expansion-focused 2026 outlook from the earnings call. This is tempered by mixed cash-flow quality (free cash flow negative in 2025), bearish technical momentum, and limited valuation support from a negative P/E and no dividend yield data.
Positive Factors
Consistent revenue growth and return to profitability
Sustained top-line growth and a structural return to profitability in 2025 indicate the core business and commercial channels are scaling. Persistent revenue expansion plus positive net income improve cash generation potential and support reinvestment, deleveraging, and long-term operational stability.
High gross margins and guided margin expansion
Robust gross margins and explicit guidance for margin expansion reflect durable product-level economics and favorable mix (U.S. AMDS and On‑X). High margins provide structural flexibility to absorb R&D and CapEx while sustaining operating profitability as volumes scale across geographies.
Clinical and pipeline progress expanding TAM
Positive IDE/PMA results and active enrollment (AMDS, NEXUS, ARTISAN) materially derisk regulatory pathways and expand addressable markets. Clinical validation supports longer-term adoption, opens incremental revenue pools, and underpins sustained multi-year growth beyond current product franchises.
Negative Factors
Weak free cash flow and cash conversion
Negative free cash flow despite positive net income signals structural cash conversion inefficiency driven by reinvestments or working capital. This constrains the company’s ability to self-fund growth, deleveraging, or acquisitions and increases reliance on external financing over the medium term.
Elevated CapEx and rising R&D commitment
Higher structural investment to scale On‑X capacity and advance pipeline increases cash demands and pressure on near-term free cash flow. Persistent elevated CapEx/R&D narrows margin upside and reduces financial flexibility until revenue from these investments materializes, raising execution risk.
Commercialization and adoption risk for new products
New device rollouts face structural adoption frictions—training, local regulatory processes, and limited initial account access—that slow revenue conversion. Protracted commercial ramps increase sales costs and delay returns on R&D/CapEx, making near-term growth and margin targets contingent on execution.

Artivion (AORT) vs. SPDR S&P 500 ETF (SPY)

Artivion Business Overview & Revenue Model

Company DescriptionArtivion Inc. manufactures, processes, and distributes medical devices and implantable human tissues worldwide. The company offers BioGlue, a polymer consisting of bovine blood protein and an agent for cross-linking proteins for cardiac, vascular, neurologic, and pulmonary procedures; cardiac preservation services; PhotoFix, a bovine pericardial patch; and E-vita Open Plus and E-vita Open Neo. It also provides E-xtra design engineering systems for the treatment of aortic vascular diseases; E-nside, an off-the-shelf stent graft for the treatment of thoraco-abdominal disease; E-vita THORACIC 3G for the endovascular treatment of thoracic aortic aneurysms; E-nya, a thoracic stent graft system for the minimally invasive repair of lesions of the descending aorta; E-ventus BX, a balloon-expandable peripheral stent graft for the endovascular treatment of renal and pelvic arteries; E-liac to treat aneurysmal iliac arteries, and aneurysmal iliac side branches; and E-tegra, an abdominal aortic aneurysms stent graft system. In addition, the company offers synthetic vascular grafts for use in open aortic and peripheral vascular surgical procedures; PerClot, an absorbable powdered hemostat for use in surgical procedures; cardiac laser therapy products for angina treatment; CryoVein femoral vein and CryoArtery femoral artery vascular preservation services; On-X prosthetic aortic and mitral heart valves and the On-X ascending aortic prosthesis; CarbonAid CO2 diffusion catheters and Chord-X ePTFE sutures for mitral chordal replacement; and ascyrus medical dissection stents, as well as pyrolytic carbon coating services to medical device manufacturers. It serves physicians, hospitals, and other healthcare facilities, as well as cardiac, vascular, thoracic, and general surgeons. The company was formerly known as CryoLife, Inc. and changed its name to Artivion Inc. in January 2022. The company was founded in 1984 and is headquartered in Kennesaw, Georgia.
How the Company Makes MoneyArtivion generates revenue primarily through the sale of its medical devices and surgical products, which are utilized in hospitals and surgical centers worldwide. The company has established key revenue streams through direct sales to healthcare providers, as well as distribution agreements with various partners in the medical field. Significant partnerships with major healthcare organizations and ongoing research and development efforts contribute to its earnings by expanding its product offerings and enhancing its market presence. Additionally, Artivion invests in clinical studies to validate the efficacy of its products, which can lead to increased adoption and sales in the marketplace.

Artivion Earnings Call Summary

Earnings Call Date:Feb 12, 2026
(Q4-2025)
|
% Change Since: |
Next Earnings Date:Apr 30, 2026
Earnings Call Sentiment Positive
The call presented a strong favorable financial and clinical story: double-digit revenue growth, outsized EBITDA expansion, margin improvement, deleveraging, positive clinical data, and clear 2026 guidance. Key challenges remain from the 2024 cybersecurity incident, a softer-than-expected tissue business, an Italian payback adjustment, elevated near-term CapEx and R&D spend, and early-stage commercial execution for new products (AMDS, NEXUS). Overall, positives (growth, margins, clinical/regulatory progress, regional strength, leverage improvement) materially outweigh the operational and legacy headwinds.
Q4-2025 Updates
Positive Updates
Full-Year Revenue and EBITDA Growth
Total adjusted constant currency revenue grew 13% for FY2025 to $443.6M, while adjusted EBITDA grew 26% year-over-year with an adjusted EBITDA margin of 20.2% (up 190 basis points).
Strong Fourth Quarter Results
Q4 adjusted revenues were $118.3M (excluding Italian payback), up 18.5% YoY. Q4 adjusted EBITDA increased ~29% from $17.6M to $22.7M, and adjusted EBITDA margin improved to 19.2% (up ~110 basis points YoY).
Stent Graft Momentum
Stent graft revenues grew 36% YoY in Q4 on a constant currency basis (28% growth when adjusting for the 2024 cyber incident), cited as a foundational growth driver with plans to expand U.S. and Japan commercialization.
On-X Growth and Market Opportunity
On-X revenues grew 24% YoY in Q4 on a constant currency basis. Management forecasts mid-teens growth for On-X in 2026 and identifies a $100M incremental U.S. market opportunity based on new clinical data.
Clinical and Regulatory Progress
Positive clinical updates: AMDS PERSEVERE two-year data reinforced benefits; NEXUS TRIUMPH one-year IDE results showed 94% survival from lesion-related death, 91% free from stroke, and 97% free from renal reinterventions. Fourth/final AMDS PMA module filed; AMDS PMA targeted mid-2026; NEXUS and other PMA timelines noted.
Regional Revenue Strength
Q4 regional constant currency growth: Asia Pacific +32%, North America +18%, EMEA +17%, Latin America +9% YoY, indicating broad geographic momentum.
Balance Sheet and Leverage Improvement
Year-end cash of ~$64.9M and debt of $215.1M; net leverage ratio improved to 1.8x from 3.8x year-over-year, signaling meaningful deleveraging.
2026 Outlook with Continued Growth and Margin Expansion
Guidance for 2026: constant currency revenue growth of 10%-14% (reported revenue $486M-$504M) and adjusted EBITDA of $105M-$110M (18%-22% growth), with expected ~150 basis points of adjusted EBITDA margin expansion at midpoint and slightly positive free cash flow.
Pipeline and Longer-Term TAM Opportunities
ARTISAN (Arecibo LSA) enrollment underway (8 of 132 patients), expected enrollment complete mid-2027 and potential FDA approval in 2029, representing an incremental ~$80M U.S. market opportunity.
Negative Updates
Legacy Cybersecurity Impact
2024 cybersecurity incident negatively impacted revenue by ~$4.5M in Q4 2024 (approximately $2.0M stent grafts and $2.5M tissue processing), complicating year-over-year comps and lingering impacts into 2025.
Tissue Processing Underperformance
Tissue processing growth was mixed: Q4 tissue processing revenue rose 6% YoY on a constant currency basis, but excluding the cyber impact prior-year results, Q4 tissue declined 4% YoY and full-year tissue revenue declined 3%, coming in below expectations.
Italian Government Payback Adjustment
Recorded a $2.3M revenue adjustment in Q4 for estimated payback obligations (2019–2025) related to Italian legislation; excluded from adjusted revenue but reduced reported gross margin and added OUS uncertainty.
Gross Margin and Manufacturing Inefficiencies
Q4 gross margin was 63% (flat YoY) but was negatively impacted by ~1 percentage point from the Italian payback and by manufacturing inefficiencies; 2024 margins were previously reduced ~2 percentage points by an idle plant charge due to the cyber incident.
Free Cash Flow and One-Time Cash Outlays
Full-year free cash flow was modest at approximately $1M despite profitability, partly because of one-time cash payments of ~$20M to acquire two Austin facilities and elevated capital investment plans.
Elevated CapEx and R&D Pressure
CapEx expected to rise to ~ $50M in 2026 (from $39M in 2025) to support On-X capacity and systems; R&D spend expected to increase to ~8% of sales in 2026 (up ~100 basis points), which Management noted will pressure EBITDA leverage versus the company’s 2x revenue-to-EBITDA target.
Commercial and Adoption Risks for New Products
AMDS commercialization still early (management estimated only ~10% of target accounts opened), HDE requires local IRB processes that create administrative friction, and NEXUS commercialization requires more intensive training and will target a smaller number of high-volume centers—creating timing/uptake uncertainty.
Company Guidance
Artivion guided 2026 constant‑currency revenue growth of 10–14% (reported revenue $486–$504M) with adjusted EBITDA of $105–$110M (roughly 18–22% growth vs. 2025), implying ~150 bps of adjusted EBITDA margin expansion at the midpoint; gross margin is expected to improve ~50 bps (driven by U.S. AMDS and U.S. On‑X mix), SG&A leverage of ~200 bps, R&D to increase ~100 bps to about 8% of sales, CapEx of approximately $50M (vs. $39M in 2025), free cash flow slightly positive, and interest expense roughly in line with the Q4 exit rate. Product assumptions: tissue flat, BioGlue mid‑single‑digit growth, On‑X mid‑teens, and stent grafts low‑20s; Q1 growth is expected toward the high end of the range with lower, similar growth in Q2–Q4. Guidance excludes any impact from a potential EndoSpan acquisition.

Artivion Financial Statement Overview

Summary
Improving fundamentals with steady revenue growth and a return to profitability in 2025, plus better leverage (debt-to-equity down materially). Offsetting this, profitability is still thin and cash-flow quality is a key concern: free cash flow turned slightly negative in 2025 despite positive net income.
Income Statement
66
Positive
Revenue has grown consistently, accelerating to 4.4% in 2025 after strong growth in 2021–2023. Profitability has improved meaningfully: the company moved from net losses in 2020–2024 to positive net income in 2025, supported by solid gross margins (~61–66%) and healthier operating profitability (EBIT margin ~6.1% in 2025). The main weakness is that net profitability remains thin (net margin ~2.2% in 2025) and results have been volatile, with a loss as recently as 2024.
Balance Sheet
62
Positive
Leverage improved materially in 2025, with debt-to-equity dropping to ~0.65 from ~1.25–1.31 in 2022–2024, alongside higher equity and a larger asset base. Return on equity also turned positive in 2025 (~2.2%) after several years of negative returns, signaling better earnings quality. Key risk remains the still sizable absolute debt balance and historically elevated leverage, which can constrain flexibility if profitability weakens.
Cash Flow
44
Neutral
Operating cash flow has improved and remained positive in 2023–2025 (about $38.1M in 2025 vs. $22.2M in 2024), indicating better underlying cash generation versus earlier periods of negative operating cash flow (2021–2022). However, free cash flow deteriorated sharply in 2025, turning slightly negative (about -$0.9M) after being positive in 2023–2024, suggesting higher reinvestment needs or working-capital pressure. Cash conversion is also a concern, as free cash flow did not consistently track reported earnings (negative free cash flow relative to net income in 2025).
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue441.33M388.54M354.00M313.79M298.84M
Gross Profit270.45M248.78M229.18M202.52M197.51M
EBITDA49.20M50.97M26.79M25.68M26.04M
Net Income9.77M-13.36M-30.69M-19.19M-14.83M
Balance Sheet
Total Assets884.80M789.10M792.40M762.80M793.05M
Cash, Cash Equivalents and Short-Term Investments64.91M53.46M58.94M39.35M55.01M
Total Debt292.04M362.26M358.34M356.83M362.04M
Total Liabilities436.56M512.90M510.62M478.47M492.32M
Stockholders Equity448.23M276.20M281.78M284.33M300.73M
Cash Flow
Free Cash Flow-911.00K11.05M11.39M-15.87M-15.68M
Operating Cash Flow38.13M22.24M18.82M-5.15M-2.58M
Investing Cash Flow-42.04M-28.19M-502.00K-10.71M5.66M
Financing Cash Flow13.03M2.20M865.00K-1.64M-12.22M

Artivion Technical Analysis

Technical Analysis Sentiment
Negative
Last Price37.39
Price Trends
50DMA
42.89
Negative
100DMA
43.45
Negative
200DMA
39.00
Negative
Market Momentum
MACD
-1.53
Positive
RSI
34.38
Neutral
STOCH
56.74
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AORT, the sentiment is Negative. The current price of 37.39 is below the 20-day moving average (MA) of 39.70, below the 50-day MA of 42.89, and below the 200-day MA of 39.00, indicating a bearish trend. The MACD of -1.53 indicates Positive momentum. The RSI at 34.38 is Neutral, neither overbought nor oversold. The STOCH value of 56.74 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AORT.

Artivion Risk Analysis

Artivion disclosed 33 risk factors in its most recent earnings report. Artivion reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Artivion Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
64
Neutral
$1.77B-714.49-1.90%18.72%85.77%
63
Neutral
$3.68B-16.93-17.63%8.97%-1024.86%
59
Neutral
$1.78B190.29-2.45%9.81%-1067.00%
56
Neutral
$682.98M-30.27-12.91%23.27%43.90%
53
Neutral
$544.89M-4.53-24.60%4.31%3.26%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
$933.93M-1.87-38.71%4.99%-7151.40%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AORT
Artivion
37.39
9.54
34.25%
IART
Integra Lifesciences
11.76
-10.29
-46.67%
OFIX
Orthofix Medical
13.59
-4.56
-25.12%
AXGN
AxoGen
35.38
17.37
96.45%
LIVN
LivaNova
68.35
18.85
38.08%
SIBN
SI-Bone
15.62
-1.85
-10.59%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 14, 2026