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Equillium (EQ)
NASDAQ:EQ
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Equillium (EQ) AI Stock Analysis

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EQ

Equillium

(NASDAQ:EQ)

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Neutral 53 (OpenAI - 5.2)
Rating:53Neutral
Price Target:
$2.50
▲(21.95% Upside)
Action:Reiterated
Date:06/04/26
The score is weighed down primarily by deteriorated financial performance (near-zero TTM revenue, persistent losses, and significant cash burn). This is partially offset by strong technical momentum and a positive financing event that improves runway, while valuation remains constrained by ongoing unprofitability and lack of dividend support.
Positive Factors
Very low leverage
Extremely low debt reduces solvency and interest-rate risk, giving management flexibility to prioritize R&D and clinical programs without large fixed financing costs. For a clinical-stage biotech, minimal leverage materially improves runway management and lowers bankruptcy risk while pursuing partnerships.
Negative Factors
Near-zero revenue and persistent losses
The collapse to near-zero revenue and recurring operating losses mean the company cannot self-fund development from product cash flow. This structural gap forces ongoing financing, reduces bargaining power with partners, and lengthens the timeline to positive returns until a commercial product or material partnership is secured.
Read all positive and negative factors
Positive Factors
Negative Factors
Very low leverage
Extremely low debt reduces solvency and interest-rate risk, giving management flexibility to prioritize R&D and clinical programs without large fixed financing costs. For a clinical-stage biotech, minimal leverage materially improves runway management and lowers bankruptcy risk while pursuing partnerships.
Read all positive factors

Equillium (EQ) vs. SPDR S&P 500 ETF (SPY)

Equillium Business Overview & Revenue Model

Company Description
Equillium, Inc. is a clinical-stage biopharmaceutical company focused on developing and bringing to market products designed to address severe autoimmune and inflammatory (immuno-inflammatory) disorders where current treatment options are insuffic...
How the Company Makes Money
Equillium is a clinical-stage biotech company and, as such, it does not primarily generate recurring revenue from marketed products. Its cash generation has historically depended on external funding and collaboration-related inflows rather than pr...

Equillium Financial Statement Overview

Summary
Operating fundamentals are weak: TTM revenue has fallen to near-zero and the company remains deeply unprofitable (EBIT about -$20.4M; net loss about -$19.1M) with heavy ongoing cash burn (TTM FCF about -$18.9M). A key positive is very low leverage (debt-to-equity ~0.01), but negative returns on equity and funding dependence remain major risks.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
28
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.0041.09M36.08M15.76M0.00
Gross Profit-79.00K-116.00K41.09M36.08M15.76M-72.00K
EBITDA-18.95M-22.28M-7.57M-12.14M-61.26M-37.91M
Net Income-19.05M-22.40M-8.07M-13.34M-62.43M-38.98M
Balance Sheet
Total Assets63.08M31.89M25.60M50.53M78.42M85.41M
Cash, Cash Equivalents and Short-Term Investments61.32M30.28M22.57M40.87M71.02M80.71M
Total Debt692.00K719.00K384.00K824.00K10.19M11.79M
Total Liabilities3.60M3.29M6.54M27.96M46.48M18.90M
Stockholders Equity59.49M28.60M19.06M22.57M31.94M66.50M
Cash Flow
Free Cash Flow-18.93M-22.79M-19.11M-21.83M-9.01M-32.14M
Operating Cash Flow-18.88M-22.75M-19.03M-21.78M-8.73M-32.08M
Investing Cash Flow-35.00K4.46M13.81M-4.76M18.68M27.41M
Financing Cash Flow65.68M30.43M164.00K-9.23M-1.22M31.06M

Equillium Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price2.05
Price Trends
50DMA
2.69
Negative
100DMA
2.34
Positive
200DMA
1.82
Positive
Market Momentum
MACD
-0.04
Positive
RSI
40.10
Neutral
STOCH
15.24
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For EQ, the sentiment is Neutral. The current price of 2.05 is below the 20-day moving average (MA) of 2.86, below the 50-day MA of 2.69, and above the 200-day MA of 1.82, indicating a neutral trend. The MACD of -0.04 indicates Positive momentum. The RSI at 40.10 is Neutral, neither overbought nor oversold. The STOCH value of 15.24 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for EQ.

Equillium Risk Analysis

Equillium disclosed 83 risk factors in its most recent earnings report. Equillium reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Equillium Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$179.10M-3.26107.73%36.33%
54
Neutral
$68.20M-7.03-63.24%-24.34%83.13%
53
Neutral
$163.76M-6.56-61.43%-100.00%18.25%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
44
Neutral
$334.51M-3.83-118.24%138.86%42.14%
42
Neutral
$390.57M-0.07275.30%49.94%44.76%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
EQ
Equillium
2.47
2.08
531.71%
NRXP
NRX Pharmaceuticals
4.18
1.19
39.80%
STRO
Sutro Biopharma
22.59
14.02
163.59%
HYFT
MindWalk Holdings
1.43
-0.27
-15.88%
PRLD
Prelude Therapeutics
4.06
3.21
377.65%

Equillium Corporate Events

Business Operations and StrategyExecutive/Board ChangesShareholder MeetingsStock Split
Equillium Shareholders Approve Reverse Split and Capital Changes
Neutral
May 29, 2026
On May 28, 2026, Equillium, Inc. held its 2026 annual meeting of stockholders, with approximately 85.86% of outstanding shares represented in person or by proxy, and shareholders elected Charles McDermott and Bruce Steel as Class II directors to s...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 04, 2026