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Equillium Inc (EQ)
NASDAQ:EQ
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Equillium (EQ) AI Stock Analysis

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EQ

Equillium

(NASDAQ:EQ)

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Neutral 54 (OpenAI - 5.2)
Rating:54Neutral
Price Target:
$2.00
▼(-2.44% Downside)
Action:Reiterated
Date:05/14/26
The score is held down primarily by weak financial performance—near-zero TTM revenue, ongoing losses, and significant cash burn—despite the benefit of low leverage. Offsetting factors include improving technical momentum (price above key moving averages with supportive MACD/RSI) and a positive corporate event that strengthens funding runway, while valuation remains constrained by unprofitability and the lack of a dividend.
Positive Factors
Focused immunomodulatory pipeline
Equillium’s strategy centers on targeted immunomodulatory biologics (itolizumab and EQ504), a durable scientific niche. A focused pipeline increases chances for clinical validation, partnership interest, and milestone-based financing, supporting long-term value creation if trials progress.
Negative Factors
Collapse to near-zero revenue
Revenue has effectively disappeared, removing any self-funding from operations and signaling loss of prior partner or commercial receipts. Sustained zero revenue forces reliance on external capital and means the business lacks recurring cash generation while clinical programs mature.
Read all positive and negative factors
Positive Factors
Negative Factors
Focused immunomodulatory pipeline
Equillium’s strategy centers on targeted immunomodulatory biologics (itolizumab and EQ504), a durable scientific niche. A focused pipeline increases chances for clinical validation, partnership interest, and milestone-based financing, supporting long-term value creation if trials progress.
Read all positive factors

Equillium (EQ) vs. SPDR S&P 500 ETF (SPY)

Equillium Business Overview & Revenue Model

Company Description
Equillium, Inc., a clinical-stage biotechnology company, develops and sells products to treat severe autoimmune and inflammatory, or immuno-inflammatory disorders with unmet medical need. The company's lead product candidate is itolizumab (EQ001),...
How the Company Makes Money
Equillium does not have a broadly disclosed, established product-sales business model; as a clinical-stage biotech, it typically funds operations primarily through external financing rather than recurring commercial revenue. Material revenue, to t...

Equillium Financial Statement Overview

Summary
Operating fundamentals are weak: TTM revenue is effectively zero after a sharp drop from 2024, while losses remain large (EBIT about -$20.4M; net loss about -$19.1M). The balance sheet is low-leverage (debt-to-equity ~0.01), but returns remain strongly negative and cash burn is heavy (TTM operating cash flow and free cash flow both about -$18.9M), implying continued funding dependence.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
28
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.0041.09M36.08M15.76M0.00
Gross Profit-79.00K0.0041.09M36.08M15.76M-72.00K
EBITDA-20.27M-23.52M-7.57M-12.14M-61.26M-37.91M
Net Income-19.05M-22.40M-8.07M-13.34M-62.43M-38.98M
Balance Sheet
Total Assets63.08M31.89M25.60M50.53M78.42M85.41M
Cash, Cash Equivalents and Short-Term Investments61.32M30.28M22.57M40.87M71.02M80.71M
Total Debt692.00K719.00K384.00K824.00K10.19M11.79M
Total Liabilities3.60M3.29M6.54M27.96M46.48M18.90M
Stockholders Equity59.49M28.60M19.06M22.57M31.94M66.50M
Cash Flow
Free Cash Flow-18.93M-22.79M-19.11M-21.83M-9.01M-32.14M
Operating Cash Flow-18.88M-22.75M-19.03M-21.78M-8.73M-32.08M
Investing Cash Flow-35.00K4.46M13.81M-4.76M18.68M27.41M
Financing Cash Flow65.68M30.43M164.00K-9.23M-1.22M31.06M

Equillium Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2.05
Price Trends
50DMA
1.88
Positive
100DMA
1.54
Positive
200DMA
1.34
Positive
Market Momentum
MACD
0.01
Negative
RSI
54.51
Neutral
STOCH
69.82
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For EQ, the sentiment is Positive. The current price of 2.05 is above the 20-day moving average (MA) of 1.95, above the 50-day MA of 1.88, and above the 200-day MA of 1.34, indicating a bullish trend. The MACD of 0.01 indicates Negative momentum. The RSI at 54.51 is Neutral, neither overbought nor oversold. The STOCH value of 69.82 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for EQ.

Equillium Risk Analysis

Equillium disclosed 82 risk factors in its most recent earnings report. Equillium reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 3 New Risks
1.
We are a "smaller reporting company" and a "non-accelerated filer" and any decision on our part to comply only with certain reduced reporting and disclosure requirements applicable to smaller reporting companies or non-accelerated filers could make our common stock less attractive to investors. Q4, 2023
2.
We cannot guarantee that our stock repurchase program will be further consummated or will enhance stockholder value, and share repurchases could affect the price of our common stock. Q4, 2023
3.
Adverse developments affecting the financial services industry could adversely affect our current and projected business operations and our financial condition and results of operations. Q4, 2023

Equillium Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$645.75M-2.12275.30%49.94%44.76%
55
Neutral
$108.46M-12.04111.73%36.33%
54
Neutral
$137.83M-9.06-61.43%-100.00%18.25%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$282.25M-6.79-118.24%138.86%42.14%
46
Neutral
$55.59M-6.63-63.13%-24.34%83.13%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
EQ
Equillium
2.18
1.80
467.71%
NRXP
NRX Pharmaceuticals
3.28
0.84
34.43%
STRO
Sutro Biopharma
38.97
30.19
343.70%
HYFT
MindWalk Holdings
1.19
0.70
143.85%
PRLD
Prelude Therapeutics
4.48
3.56
386.96%

Equillium Corporate Events

Business Operations and StrategyPrivate Placements and FinancingRegulatory Filings and Compliance
Equillium Raises Capital Through Private Equity Securities Sale
Positive
Mar 13, 2026
On March 11, 2026, Equillium, Inc. entered into a securities purchase agreement with RA Capital Healthcare Fund, L.P. for a private placement of 1,179,508 common shares and a pre-funded warrant for up to 17,698,593 additional shares, priced off th...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 14, 2026