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Leap Therapeutics (LPTX)
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Leap Therapeutics (LPTX) AI Stock Analysis

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LPTX

Leap Therapeutics

(NASDAQ:LPTX)

Rating:31Underperform
Price Target:
Leap Therapeutics faces significant financial challenges with persistent losses and no revenue growth, resulting in a low financial performance score. The technical analysis suggests bearish trends with some potential for short-term volatility. The company’s valuation metrics are also unfavorable due to negative earnings. No recent earnings call or corporate events data are available to impact the score further.
Positive Factors
Drug Development
Additional data confirmed efficacy of DNK-01 in DKK1-high and VEGF-naïve CRC patients.
Drug Efficacy
Promising efficacy data point to market potential of DNK-01 in approximately 25%-50% of 2L patients.
Financial Stability
The company reported approximately $47M in cash and cash equivalents, which is believed to be sufficient to fund operations.
Negative Factors
Partnership Challenges
The company still needs to identify a partner to run the registrational Phase 3 study.
Pipeline Uncertainty
Uncertainties regarding the company's pipeline development and lack of meaningful catalysts contribute to the Neutral rating.

Leap Therapeutics (LPTX) vs. SPDR S&P 500 ETF (SPY)

Leap Therapeutics Business Overview & Revenue Model

Company DescriptionLeap Therapeutics, Inc., a biopharmaceutical company, acquires and develops therapies for the treatment of cancer. Its lead clinical stage programs include DKN-01, a monoclonal antibody that inhibits Dickkopf-related protein 1, which is in multiple ongoing clinical trials for treating esophagogastric, hepatobiliary, gynecologic, and prostate cancers. Leap Therapeutics, Inc. has an option and license agreement with BeiGene, Ltd. to develop and commercialize DKN-01 in Asia (excluding Japan), Australia, and New Zealand. The company was formerly known as HealthCare Pharmaceuticals, Inc. and changed its name to Leap Therapeutics, Inc. in November 2015. Leap Therapeutics, Inc. was incorporated in 2011 and is based in Cambridge, Massachusetts.
How the Company Makes MoneyLeap Therapeutics makes money primarily through the development and commercialization of its proprietary cancer treatment therapies. The company generates revenue through strategic partnerships, licensing agreements, and collaborations with larger pharmaceutical companies, which may involve upfront payments, milestone payments, and royalties on sales of successfully developed products. Leap Therapeutics may also secure funding through public and private investments to support its research and development activities.

Leap Therapeutics Financial Statement Overview

Summary
Leap Therapeutics is facing financial challenges with ongoing losses, negative cash flows, and zero revenue growth. While the low debt levels and stable equity ratio are positives, the lack of revenue and continuous cash burn are major concerns. Strategic changes are necessary for sustainable growth.
Income Statement
15
Very Negative
Leap Therapeutics has consistently reported zero revenue from 2021 to 2024 following a marginal revenue in 2020. The net income has been negative throughout, indicating persistent losses. EBIT and EBITDA margins are also negative, showcasing an ongoing struggle in generating profits.
Balance Sheet
30
Negative
The company's debt levels are low relative to equity, resulting in a low debt-to-equity ratio, which is a positive indicator. However, the continuous erosion of shareholder equity due to losses is concerning. The equity ratio remains stable, suggesting adequate asset coverage by equity.
Cash Flow
20
Very Negative
Operating cash flow is consistently negative, reflecting cash burn from operations. Free cash flow has also been negative, though there was a significant financing inflow in 2021. The company has not shown growth in free cash flow, indicating financial strain.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.001.50M1.50M
Gross Profit0.00-427.00K-415.00K1.50M1.50M
EBITDA-66.97M-80.99M-53.98M-40.01M-26.81M
Net Income-67.56M-81.41M-54.60M-40.59M-27.51M
Balance Sheet
Total Assets49.12M72.83M70.35M117.91M54.37M
Cash, Cash Equivalents and Short-Term Investments47.25M70.64M65.50M114.92M52.07M
Total Debt266.00K262.00K678.00K469.00K552.00K
Total Liabilities14.08M12.68M11.49M10.02M7.72M
Stockholders Equity35.05M60.14M58.87M107.89M46.65M
Cash Flow
Free Cash Flow-60.30M-43.75M-49.04M-35.16M-25.96M
Operating Cash Flow-60.30M-43.75M-49.04M-35.16M-25.96M
Investing Cash Flow0.0048.97M0.000.0025.00K
Financing Cash Flow37.18M-30.00K-210.00K98.03M74.00M

Leap Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.33
Price Trends
50DMA
0.35
Negative
100DMA
0.36
Negative
200DMA
1.30
Negative
Market Momentum
MACD
>-0.01
Negative
RSI
48.10
Neutral
STOCH
51.39
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For LPTX, the sentiment is Negative. The current price of 0.33 is below the 20-day moving average (MA) of 0.34, below the 50-day MA of 0.35, and below the 200-day MA of 1.30, indicating a bearish trend. The MACD of >-0.01 indicates Negative momentum. The RSI at 48.10 is Neutral, neither overbought nor oversold. The STOCH value of 51.39 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for LPTX.

Leap Therapeutics Risk Analysis

Leap Therapeutics disclosed 29 risk factors in its most recent earnings report. Leap Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Leap Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.39B0.42-62.86%2.37%15.61%-1.93%
42
Neutral
$13.14M-362.79%32.45%39.31%
41
Neutral
$18.59M-491.97%24.16%
39
Underperform
$13.36M-26.83%86.44%
33
Underperform
$11.75M-339.64%-75.88%
31
Underperform
$13.63M-202.81%64.01%
28
Underperform
$15.68M-383.73%99.43%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LPTX
Leap Therapeutics
0.33
-1.87
-85.00%
IMNN
Imunon
8.76
-8.04
-47.86%
XTLB
XTL Biopharmaceuticals Sponsored ADR
1.45
-1.08
-42.69%
CARM
Carisma Therapeutics
0.31
-0.59
-65.56%
MTVA
MetaVia
0.60
-3.20
-84.21%
ALLR
Allarity Therapeutics
1.04
-3.21
-75.53%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 30, 2025