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MetaVia (MTVA)
NASDAQ:MTVA
US Market
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MetaVia (MTVA) AI Stock Analysis

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MTVA

MetaVia

(NASDAQ:MTVA)

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Neutral 45 (OpenAI - 5.2)
Rating:45Neutral
Price Target:
$1.50
▲(7.14% Upside)
Action:Reiterated
Date:07/10/26
The score is held down primarily by weak financial performance (no revenue, ongoing losses and cash burn) and a bearish technical trend (price below key moving averages with negative MACD). Corporate updates around DA-1726 are supportive, but the need for funding (including an ATM program) and limited meaningful valuation metrics cap the rating.
Positive Factors
Clinical Efficacy of DA-1726
Durable clinical signal: reproducible ~9% weight loss in Phase 1 higher-dose cohorts demonstrates meaningful pharmacologic activity and potential differentiation vs existing GLP-1 drugs. Strong early efficacy supports continued development, partner interest, and value creation in a large obesity market over months.
Negative Factors
Pre-Revenue Status and Ongoing Losses
Structural limitation: without commercial revenue the company must rely on funding to sustain R&D. Persistent multi‑million dollar losses mean value depends entirely on clinical progress and external financing, increasing execution risk if trials or endpoints underperform or timelines slip.
Read all positive and negative factors
Positive Factors
Negative Factors
Clinical Efficacy of DA-1726
Durable clinical signal: reproducible ~9% weight loss in Phase 1 higher-dose cohorts demonstrates meaningful pharmacologic activity and potential differentiation vs existing GLP-1 drugs. Strong early efficacy supports continued development, partner interest, and value creation in a large obesity market over months.
Read all positive factors

MetaVia (MTVA) vs. SPDR S&P 500 ETF (SPY)

MetaVia Business Overview & Revenue Model

Company Description
Headquartered in Cambridge, Massachusetts, MetaVia Inc. operates as a clinical-stage biotechnology company with a core focus on discovering and commercializing novel pharmaceutical solutions for cardiometabolic disorders. Its leading investigation...

MetaVia Financial Statement Overview

Summary
Weak fundamentals typical of an early-stage biotech: $0 revenue, ongoing net losses (~$13.1M TTM) and persistent cash burn (~-$15.1M TTM). Positives include materially reduced losses versus 2024 and very low leverage (debt-to-equity ~0.04), but shrinking equity and continued reliance on external funding keep the financial profile below average.
Income Statement
8
Very Negative
Balance Sheet
56
Neutral
Cash Flow
12
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Mar 2022
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-15.00K-19.00K-24.00K-7.00K-28.00K-72.00K
EBITDA-13.11M-12.95M-27.57M-12.46M-11.76M-15.24M
Net Income-13.13M-12.97M-27.59M-12.47M-13.97M-15.28M
Balance Sheet
Total Assets14.39M69.12M16.26M22.78M33.53M16.80M
Cash, Cash Equivalents and Short-Term Investments13.73M10.28M16.02M22.43M33.36M16.39M
Total Debt194.00K210.00K136.00K203.00K0.0071.00K
Total Liabilities5.32M63.79M8.33M6.10M11.78M2.20M
Stockholders Equity9.07M5.33M7.93M16.68M21.75M14.60M
Cash Flow
Free Cash Flow-15.15M-15.70M-24.72M-10.85M-11.71M-15.14M
Operating Cash Flow-15.14M-15.70M-24.71M-10.80M-11.71M-15.13M
Investing Cash Flow-2.00K-2.00K-8.00K-50.00K8.00K-586.00K
Financing Cash Flow17.69M9.96M18.30M-80.00K28.68M22.03M

MetaVia Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price1.40
Price Trends
50DMA
1.85
Negative
100DMA
1.66
Positive
200DMA
4.82
Negative
Market Momentum
MACD
-0.10
Negative
RSI
52.01
Neutral
STOCH
84.71
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MTVA, the sentiment is Neutral. The current price of 1.4 is below the 20-day moving average (MA) of 1.60, below the 50-day MA of 1.85, and below the 200-day MA of 4.82, indicating a neutral trend. The MACD of -0.10 indicates Negative momentum. The RSI at 52.01 is Neutral, neither overbought nor oversold. The STOCH value of 84.71 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for MTVA.

MetaVia Risk Analysis

MetaVia disclosed 66 risk factors in its most recent earnings report. MetaVia reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

MetaVia Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$83.90M-10.54-14.39%1.18%83.26%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
$30.71M-0.599999.00%-1753.64%
45
Neutral
$8.93M-0.29-229.48%83.72%
44
Neutral
$15.41M-0.23-67.42%55.15%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MTVA
MetaVia
1.78
-6.12
-77.47%
PMN
ProMIS Neurosciences
14.25
4.49
46.00%
CTXR
Citius Pharmaceuticals
0.58
-0.98
-62.69%
RLYB
Rallybio
15.73
12.48
384.15%
KAPA
Kairos Pharma, Ltd.
0.35
-0.36
-50.42%

MetaVia Corporate Events

Business Operations and StrategyProduct-Related Announcements
MetaVia Advances DA-1726 Obesity Trial to Top Doses
Positive
Jul 9, 2026
On July 9, 2026, MetaVia announced that all enrolled active patients in Part 3 of its Phase 1 clinical trial of DA-1726 for obesity have successfully completed dose titration and are now receiving the highest target doses of 48 mg and 64 mg. Part ...
Business Operations and StrategyPrivate Placements and FinancingRegulatory Filings and Compliance
MetaVia Announces $4 Million At-The-Market Stock Offering
Positive
Jul 2, 2026
On November 6, 2025, MetaVia Inc. entered into an at-the-market offering agreement with Ladenburg Thalmann Co. Inc., allowing the company to sell shares of its common stock from time to time through or to Ladenburg under Rule 415(a)(4) of the U.S...
Executive/Board ChangesShareholder MeetingsStock Split
MetaVia Shareholders Approve Equity Plan and Reverse Split
Neutral
Jun 8, 2026
At its virtual annual meeting of stockholders held on June 8, 2026, MetaVia Inc. secured shareholder approval for the first amendment to its 2022 Amended and Restated Equity Incentive Plan, increasing the pool of shares available for equity awards...
Business Operations and StrategyProduct-Related Announcements
MetaVia highlights obesity and metabolic pipeline advancements
Positive
Jun 8, 2026
On June 8, 2026, MetaVia reported new late-breaking clinical and preclinical data from the ADA 2026 Scientific Sessions in New Orleans, underscoring the potential differentiation of its obesity and metabolic pipeline. The Phase 1 multiple ascendin...
Business Operations and StrategyProduct-Related Announcements
MetaVia highlights promising Phase 1 obesity drug data
Positive
May 27, 2026
On May 27, 2026, MetaVia reported new higher-dose Phase 1 data for its dual GLP-1/glucagon agonist DA-1726 at the EASL Congress, showing up to 9.1% mean body-weight loss at Day 54 and nearly 10 cm waist reduction in obese but otherwise healthy adu...
Business Operations and StrategyProduct-Related Announcements
MetaVia Showcases Key Cardiometabolic Data at ADA 2026
Positive
May 18, 2026
MetaVia Inc., a clinical-stage biotechnology company specializing in therapies for cardiometabolic diseases such as obesity and MASH, is advancing a pipeline led by DA-1726, a dual GLP-1/glucagon oxyntomodulin analog, and vanoglipel, a GPR119 agon...
Business Operations and StrategyFinancial DisclosuresPrivate Placements and Financing
MetaVia Highlights Strong DA-1726 Phase 1 Weight-Loss Data
Positive
May 14, 2026
MetaVia Inc., a clinical-stage biotech focused on cardiometabolic diseases, is advancing two lead programs: DA-1726 for obesity and vanoglipel for MASH, supported by extensive global patent portfolios licensed from Dong-A ST. The company’s p...
Business Operations and StrategyProduct-Related Announcements
MetaVia to Present New DA-1726 Obesity Data at EASL
Positive
May 11, 2026
MetaVia Inc., a Nasdaq-listed clinical-stage biotech based in Cambridge, Mass., is developing DA-1726 for obesity and vanoglipel for MASH, aiming to reshape treatment of cardiometabolic diseases with gut hormone-based therapeutics. DA-1726, an oxy...
Business Operations and StrategyProduct-Related Announcements
MetaVia Advances DA-1726 Obesity Trial With First Patient
Positive
Apr 10, 2026
On April 10, 2026, MetaVia Inc. announced it had dosed the first patient in Part 3 of its Phase 1 clinical trial of DA-1726, a dual oxyntomodulin analog targeting GLP-1 and glucagon receptors for the treatment of obesity. The new 16-week study seg...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 10, 2026