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MetaVia (MTVA)
NASDAQ:MTVA
US Market

MetaVia (MTVA) AI Stock Analysis

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MTVA

MetaVia

(NASDAQ:MTVA)

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Neutral 46 (OpenAI - 5.2)
Rating:46Neutral
Price Target:
$3.00
▼(-3.54% Downside)
The score is held down primarily by persistent pre-revenue losses and worsening cash burn with a shrinking equity base, implying continued funding risk. Technicals also point to a clear downtrend despite oversold readings. Offsetting these are multiple positive clinical readouts and a recent financing that strengthens near-term liquidity and reduces listing-related risk.
Positive Factors
Positive clinical readouts (DA-1726)
Statistically significant Phase 1 DA-1726 results demonstrating weight loss, metabolic and hepatic improvements materially de-risk the lead dual-agonist program. Sustained positive safety and biological signal bolster the asset’s odds of advancing to pivotal studies and long-term commercial potential.
Strengthened near-term liquidity
The recent $7.7M net proceeds from the public offering materially extends runway to fund ongoing DA-1726 and vanoglipel studies. This reduces immediate funding pressure, supports planned clinical milestones, and lowers near-term listing and operational continuity risk while management advances development plans.
Low financial leverage
Minimal debt provides structural financial flexibility, limiting fixed obligations and bankruptcy risk. This allows management to prioritize clinical investment or execute strategic financing on better terms without near-term interest burden, preserving optionality as pipeline value crystallizes.
Negative Factors
No revenue and widening losses
Persistent pre-revenue status and materially larger operating losses mean the company lacks internal cash generation and must rely on external capital to progress trials. Over the medium term this elevates execution risk and creates dependency on financing timing and terms for program continuity.
Accelerating cash burn
Rapidly worsening operating cash flow signals heavy near-term funding needs; free cash flow closely tracks net loss, indicating cash-out operations rather than paper charges. Sustained negative cash flow increases dilution risk and could force hasty financing or program delays absent durable revenue or larger financing.
Shrinking equity and dilutive financing overhang
Declining equity reduces the capital cushion and heightens reliance on external raises. The use of immediately exercisable warrants in the recent offering creates potential dilution and an overhang tied to clinical triggers, which can hamper shareholder value and complicate future non-dilutive financing options.

MetaVia (MTVA) vs. SPDR S&P 500 ETF (SPY)

MetaVia Business Overview & Revenue Model

Company DescriptionMetaVia Inc., a clinical-stage biotechnology company focuses on developing and commercializing novel pharmaceuticals to treat cardiometabolic diseases. It develops DA-1241, a novel G-Protein-Coupled Receptor 119 agonist with development optionality as a standalone and/or combination therapy that is in Phase 2a clinical trial for metabolic dysfunction-associated steatohepatitis (MASH), and has completed Phase 1 clinical trial for the treatment of type 2 diabetes mellitus (T2DM); and DA-1726, a novel oxyntomodulin analogue functioning as a GLP-1 receptor and glucagon receptor dual agonist, which is in preclinical development for the treatment of obesity. The company's therapeutic programs include ANA001, a proprietary oral niclosamide formulation for the treatment of patients with moderate COVID-19; NB-01 for the treatment of painful diabetic neuropathy; NB-02 for the treatment of cognitive impairment; and Gemcabene for the treatment of dyslipidemia. It has a license agreement with Pfizer Inc. for the research, development, manufacture, and commercialization of Gemcabene; and joint research agreement with Dong-A ST and ImmunoForge for the development of DA-1726. The company was formerly known as NeuroBo Pharmaceuticals, Inc. and changed its name to MetaVia Inc. in November 2024. MetaVia Inc. is headquartered in Cambridge, Massachusetts.
How the Company Makes MoneyMetaVia makes money through a diversified revenue model that includes subscription fees for access to its virtual reality platforms and premium content. Additionally, the company generates income through partnerships with other digital service providers and developers who create content for its platforms, often sharing in the revenue generated from these collaborations. Furthermore, MetaVia earns from in-app purchases and virtual goods sales within its ecosystem. Advertising is another key revenue stream, as brands pay for exposure within the virtual environments and experiences offered by MetaVia.

MetaVia Financial Statement Overview

Summary
MetaVia is facing substantial financial challenges, particularly with a lack of revenue and persistent losses. While the company maintains low debt levels, the reliance on equity and negative cash flows suggest operational inefficiencies and financial instability. Strategic shifts are necessary for long-term viability.
Income Statement
8
Very Negative
MetaVia's income statement shows significant challenges with no revenue generation over the past years. The company consistently reports negative net and gross profits, reflecting high operating losses. The lack of revenue growth and negative profit margins are significant concerns.
Balance Sheet
42
Neutral
The balance sheet reveals a moderate financial structure with a debt-to-equity ratio remaining low due to minimal debt. However, the decline in stockholders' equity and high liabilities relative to assets present risks. The equity ratio is decreasing, indicating reliance on liabilities.
Cash Flow
14
Very Negative
Cash flow analysis indicates consistent negative operating cash flow, highlighting operational challenges. Although free cash flow has deteriorated, the company has managed some financing cash flow. Free cash flow to net income ratio is unfavorable, reflecting cash strain.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-19.00K-24.00K-7.00K-28.00K-72.00K-67.00K
EBITDA-15.82M-28.79M-15.88M-11.76M-15.24M-29.67M
Net Income-14.82M-27.59M-12.47M-13.97M-15.28M-29.68M
Balance Sheet
Total Assets18.46M16.26M22.78M33.53M16.80M10.97M
Cash, Cash Equivalents and Short-Term Investments17.59M16.02M22.43M33.36M16.39M10.09M
Total Debt98.00K136.00K203.00K0.0071.00K94.00K
Total Liabilities8.84M8.33M6.10M11.78M2.20M3.77M
Stockholders Equity9.62M7.93M16.68M21.75M14.60M7.20M
Cash Flow
Free Cash Flow-14.09M-24.72M-10.85M-11.71M-15.14M-10.77M
Operating Cash Flow-14.09M-24.71M-10.80M-11.71M-15.13M-10.76M
Investing Cash Flow-2.00K-8.00K-50.00K8.00K-586.00K69.00K
Financing Cash Flow8.57M18.30M-80.00K28.68M22.03M6.86M

MetaVia Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.11
Price Trends
50DMA
8.27
Negative
100DMA
9.28
Negative
200DMA
8.85
Negative
Market Momentum
MACD
-1.03
Positive
RSI
25.86
Positive
STOCH
3.82
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MTVA, the sentiment is Negative. The current price of 3.11 is below the 20-day moving average (MA) of 8.03, below the 50-day MA of 8.27, and below the 200-day MA of 8.85, indicating a bearish trend. The MACD of -1.03 indicates Positive momentum. The RSI at 25.86 is Positive, neither overbought nor oversold. The STOCH value of 3.82 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for MTVA.

MetaVia Risk Analysis

MetaVia disclosed 67 risk factors in its most recent earnings report. MetaVia reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

MetaVia Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$17.81M-0.22-54.40%18.73%
48
Neutral
$27.75M-2.06-21.17%12.71%79.93%
46
Neutral
$7.18M-0.21-168.18%71.57%
45
Neutral
$17.61M-0.44-355.80%-273.84%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MTVA
MetaVia
3.11
-18.45
-85.58%
PMN
ProMIS Neurosciences
7.14
-17.58
-71.12%
CTXR
Citius Pharmaceuticals
0.86
-2.39
-73.60%
RLYB
Rallybio
0.66
-0.24
-26.62%
KAPA
Kairos Pharma, Ltd.
0.87
-0.72
-45.16%

MetaVia Corporate Events

Business Operations and StrategyPrivate Placements and Financing
MetaVia Completes Public Offering to Advance Obesity Drug
Positive
Jan 16, 2026

On January 15–16, 2026, MetaVia Inc. completed an underwritten public offering of Class A and Class B units, consisting of common stock, pre-funded warrants and Series C and Series D common warrants, raising approximately $7.7 million in net proceeds after discounts and expenses from gross proceeds of about $8.1 million. The transaction, led by Ladenburg Thalmann & Co. Inc., included full exercise of the underwriter’s over-allotment option and established a package of fixed-price, immediately exercisable warrants, some of which are subject to beneficial ownership limits and potential future callability tied to positive Phase 1b Part III data for DA-1726; MetaVia plans to deploy the capital for working capital and general corporate purposes, notably to advance clinical development of DA-1726 for obesity, reinforcing its funding base and strategic focus in the competitive cardiometabolic drug development arena.

The most recent analyst rating on (MTVA) stock is a Hold with a $5.50 price target. To see the full list of analyst forecasts on MetaVia stock, see the MTVA Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
MetaVia Reports Encouraging Phase 1 DA-1726 Obesity Data
Positive
Jan 5, 2026

On January 5, 2026, MetaVia reported positive, statistically significant data from the extended eight-week, non-titrated 48 mg multiple ascending dose cohort of its Phase 1 clinical trial of DA-1726 in obese but otherwise healthy adults, highlighting robust early weight loss, strong metabolic improvements and direct hepatic effects. Patients receiving DA-1726 achieved an average 9.1% (21.2 lb) weight loss, a 9.8 cm reduction in waist circumference, a 12.3 mg/dL drop in fasting glucose and a 23.7% reduction in liver stiffness by Day 54, with no treatment-related discontinuations and only mild to moderate gastrointestinal events, underscoring a favorable safety and tolerability profile and reinforcing DA-1726’s potential to emerge as a differentiated, best-in-class GLP-1/glucagon dual agonist in the increasingly competitive obesity and metabolic disease market.

The most recent analyst rating on (MTVA) stock is a Hold with a $9.00 price target. To see the full list of analyst forecasts on MetaVia stock, see the MTVA Stock Forecast page.

Delistings and Listing ChangesRegulatory Filings and Compliance
MetaVia Regains Nasdaq Compliance After Bid Price Recovery
Positive
Dec 19, 2025

On May 29, 2025, MetaVia Inc. was notified by Nasdaq that it was not in compliance with the exchange’s $1.00 minimum bid price requirement after its shares traded below that threshold for 30 consecutive sessions, prompting the company on November 7, 2025 to seek, and on November 26, 2025 to receive, a 180‑day extension to May 26, 2026 to cure the deficiency. The company subsequently regained compliance when its stock closed at or above $1.00 for 10 straight business days from December 5 to December 18, 2025, leading Nasdaq on December 19, 2025 to confirm that MetaVia once again met the minimum bid price standard and that the listing matter was closed, removing a near‑term risk to its continued trading on the exchange.

The most recent analyst rating on (MTVA) stock is a Buy with a $5.00 price target. To see the full list of analyst forecasts on MetaVia stock, see the MTVA Stock Forecast page.

Delistings and Listing ChangesStock Split
MetaVia Announces Reverse Stock Split to Meet Nasdaq Rules
Neutral
Dec 2, 2025

On December 2, 2025, MetaVia Inc. announced a 1-for-11 reverse stock split of its common stock, effective December 4, 2025, to comply with Nasdaq’s listing requirements. This decision, approved by the stockholders on June 30, 2025, reduces the number of outstanding shares from approximately 25.4 million to 2.3 million, while maintaining the authorized shares at 100 million. The reverse split will adjust the conversion and exercise prices of stock options and warrants proportionately, with fractional shares being rounded down and compensated in cash. The common stock will continue trading under the symbol ‘MTVA’ with a new CUSIP number.

The most recent analyst rating on (MTVA) stock is a Buy with a $5.00 price target. To see the full list of analyst forecasts on MetaVia stock, see the MTVA Stock Forecast page.

Delistings and Listing ChangesRegulatory Filings and ComplianceStock Split
MetaVia Seeks Extension to Regain Nasdaq Compliance
Negative
Nov 26, 2025

On May 29, 2025, MetaVia Inc. received a notice from Nasdaq indicating non-compliance with the minimum bid price requirement, as its stock price had been below $1.00 for 30 consecutive trading days. The company requested a 180-day extension on November 7, 2025, to regain compliance, planning to potentially implement a reverse stock split to meet the requirement.

The most recent analyst rating on (MTVA) stock is a Buy with a $5.00 price target. To see the full list of analyst forecasts on MetaVia stock, see the MTVA Stock Forecast page.

Product-Related Announcements
MetaVia Announces Positive Phase 2a Trial Results
Positive
Nov 7, 2025

On November 7, 2025, MetaVia Inc. announced positive results from its Phase 2a clinical trial of vanoglipel (DA-1241), a GPR119 agonist, as a potential treatment for MASH. The trial demonstrated vanoglipel’s ability to improve glucose control, liver health, and plasma lipidomic profiles after 16 weeks of treatment, highlighting its potential to address both hepatic and metabolic components of MASH. The data, presented at the AASLD The Liver Meeting® 2025, showed significant reductions in HbA1c, liver inflammation, and fibrosis, reinforcing vanoglipel’s potential as a monotherapy and combination therapy for MASH and related metabolic disorders.

The most recent analyst rating on (MTVA) stock is a Buy with a $12.00 price target. To see the full list of analyst forecasts on MetaVia stock, see the MTVA Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
MetaVia Releases Updated Corporate Presentation on Trials
Positive
Nov 6, 2025

On November 6, 2025, MetaVia Inc. released an updated corporate presentation detailing its ongoing clinical trials and future milestones. The company is making significant progress with its DA-1726 and Vanoglipel (DA-1241) candidates, showing promising results in weight loss and glucose control, which could enhance its market position. MetaVia is also planning further clinical trials and regulatory submissions, potentially increasing shareholder value and impacting the treatment landscape for obesity and MASH.

The most recent analyst rating on (MTVA) stock is a Buy with a $12.00 price target. To see the full list of analyst forecasts on MetaVia stock, see the MTVA Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 17, 2026