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Imunon (IMNN)
NASDAQ:IMNN
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Imunon (IMNN) AI Stock Analysis

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IMNN

Imunon

(NASDAQ:IMNN)

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Neutral 41 (OpenAI - 4o)
Rating:41Neutral
Price Target:
Imunon's financial instability, characterized by negative revenue and cash flow metrics, significantly impacts its overall stock score. Technical indicators suggest caution, with bearish trends and lack of momentum. Though the recent earnings call highlights promising clinical progress, concerns about cash runway and funding remain. Valuation metrics further reflect the stock's risky profile, with a negative P/E ratio and no dividend yield.
Positive Factors
Clinical Progress
The successful Phase 2 study results for Imunon-001 indicate strong clinical progress, enhancing the company's prospects for future product approval and commercialization in oncology.
Regulatory Advancement
FDA's supportive feedback for the Phase 3 study initiation reflects regulatory confidence in Imunon's clinical strategy, potentially accelerating market entry and revenue generation.
Leadership Strength
Dr. Faller's appointment strengthens Imunon's leadership, leveraging his extensive experience to enhance clinical strategy and drive the company's pipeline towards commercialization.
Negative Factors
Financial Instability
Persistent financial challenges, including negative revenue and cash flow, undermine Imunon's operational stability and long-term financial health, necessitating strategic restructuring.
Cash Runway Concerns
Limited cash runway highlights liquidity risks, potentially hindering Imunon's ability to sustain operations and fund ongoing clinical trials without securing additional financing.
High Leverage
High leverage suggests financial strain, limiting Imunon's flexibility to invest in growth opportunities and increasing vulnerability to market fluctuations.

Imunon (IMNN) vs. SPDR S&P 500 ETF (SPY)

Imunon Business Overview & Revenue Model

Company DescriptionImunon, Inc., a clinical stage biotechnology company, focuses on the development and commercialization of DNA-based immunotherapies, vaccines, and directed chemotherapies. Its product pipeline includes GEN-1, a DNA-based immunotherapy for the localized treatment of ovarian cancer; and ThermoDox, a proprietary heat-activated liposomal encapsulation of doxorubicin, which is in development stage for various cancer indications. The company also has two feasibility stage platform technologies for the development of nucleic acid-based immunotherapies, vaccines, and other anti-cancer DNA or RNA therapies. The company was formerly known as Celsion Corporation and changed its name to Imunon, Inc. in September 2022. Imunon, Inc. was founded in 1982 and is based in Lawrenceville, New Jersey.
How the Company Makes MoneyImunon generates revenue primarily through the development and commercialization of its proprietary therapeutic and vaccine solutions. The company may engage in licensing agreements, where it partners with other pharmaceutical or biotechnology firms to co-develop or distribute its products, thereby earning licensing fees and royalties. Additionally, Imunon may receive funding from government grants or research collaborations, which contribute to its research and development efforts. By advancing its pipeline of candidates through clinical trials and achieving regulatory approvals, Imunon positions itself to earn revenue from product sales, either directly or through strategic partnerships.

Imunon Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 26, 2026
Earnings Call Sentiment Positive
The earnings call painted a positive picture with significant progress in clinical trials and strategic planning. Despite financial constraints, the company has managed to achieve regulatory endorsements and reduce operating costs significantly. The successful engagement with the scientific community and regulatory bodies adds to the optimistic outlook, although financial limitations remain a concern.
Q3-2025 Updates
Positive Updates
Progress in OVATION 3 Trial
OVATION 3 enrollment is surging ahead of plan, with nine patients randomized by the end of October, surpassing internal targets. The trial is evaluating IMNN-001 plus standard care for advanced ovarian cancer.
R&D Day Success
A successful R&D day was hosted in New York City, featuring renowned ovarian cancer opinion leaders, clinicians, and statistical experts, highlighting the transformative potential of IMNN-001.
Regulatory Milestones
The FDA has endorsed overall survival as a single study registration endpoint, meeting expectations for approval in Europe as well.
Financial Management and Cost Reductions
Operating expenses decreased by 31% year-over-year, with R&D expenses down 44% and CMC expenses down 52%.
Shareholder Equity and NASDAQ Compliance
NASDAQ compliance matter closed with shareholder equity at $4.1 million, well above the $2.5 million threshold.
Negative Updates
Limited Cash Runway
Cash and cash equivalents stand at $5.3 million, extending the operating runway only into mid-Q1 2026.
Ongoing Financial Constraints
The company is constrained by financial resources, affecting the speed of trial enrollment and site activation.
Company Guidance
During the Imunon Third Quarter 2025 Financial Results Conference Call, the company provided several key metrics and updates on their progress. Imunon is advancing its IL-12 immunotherapy, IMNN-001, through the OVATION 3 pivotal phase III trial for advanced ovarian cancer, highlighting a potential 13-month median overall survival benefit from phase II trials, with a hazard ratio as low as 0.42 in PARP-maintained patients. The OVATION 3 trial is ahead of schedule, with nine patients enrolled by October 2025. Imunon has streamlined operations, achieving a 31% decrease in operating expenses, including a 44% reduction in R&D costs. Their cash balance of $5.3 million is expected to extend their runway into mid-Q1 2026. The company is also engaging in ongoing partnership discussions and has raised $4.5 million in the third quarter through warrant exercises and ATM facility use. Imunon's focus remains on maintaining momentum in enrollment, expanding site activations, and achieving full enrollment in OVATION 3 by late 2028, which could be accelerated with additional financing.

Imunon Financial Statement Overview

Summary
Imunon faces significant financial challenges, as indicated by consistently negative revenue, profitability, and cash flow metrics. High leverage and negative returns further exacerbate financial instability. The company needs strategic financial restructuring and improved operational performance to enhance its financial health and investor confidence.
Income Statement
10
Very Negative
Imunon has consistently reported zero or negative revenue over the past years. Gross profit margins are nonexistent, with significant net losses indicating severe profitability issues. EBIT and EBITDA margins are deeply negative, showing a lack of operational efficiency. There is no evidence of revenue growth, suggesting challenges in achieving market penetration or product commercialization.
Balance Sheet
25
Negative
The company exhibits a relatively high debt-to-equity ratio, indicating reliance on debt financing. Return on Equity (ROE) is negative, reflecting ongoing net losses. The equity ratio shows some equity presence but is overshadowed by continuous financial strain. The balance sheet stability is questionable due to high leverage and negative equity returns.
Cash Flow
20
Very Negative
Operating cash flow is consistently negative, reflecting poor cash generation from operations. Free cash flow is also negative, indicating insufficient cash to cover capital expenditures. Despite some positive financing and investing cash flow activities, the company's overall cash flow position is weak, raising concerns about liquidity and future operational funding.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.00500.00K500.00K500.00K
Gross Profit-2.66M0.000.00500.00K500.00K500.00K
EBITDA-13.81M-17.90M-19.88M-31.71M-20.88M-21.30M
Net Income-14.33M-18.62M-19.51M-35.90M-20.77M-21.48M
Balance Sheet
Total Assets8.99M9.72M21.92M43.98M74.05M37.53M
Cash, Cash Equivalents and Short-Term Investments5.25M5.87M15.70M32.75M49.39M17.16M
Total Debt1.10M1.14M1.62M6.27M6.63M6.19M
Total Liabilities4.91M5.47M8.53M14.65M18.25M18.92M
Stockholders Equity4.08M4.24M13.39M29.33M55.80M18.61M
Cash Flow
Free Cash Flow-14.95M-18.88M-19.47M-23.36M-16.54M-15.64M
Operating Cash Flow-14.66M-18.85M-19.02M-23.10M-16.22M-15.62M
Investing Cash Flow-291.89K9.83M11.01M8.28M-30.12M7.92M
Financing Cash Flow9.89M9.06M-3.64M6.72M54.77M17.98M

Imunon Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price4.12
Price Trends
50DMA
4.61
Negative
100DMA
5.58
Negative
200DMA
9.23
Negative
Market Momentum
MACD
-0.23
Negative
RSI
48.18
Neutral
STOCH
50.67
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For IMNN, the sentiment is Neutral. The current price of 4.12 is above the 20-day moving average (MA) of 3.97, below the 50-day MA of 4.61, and below the 200-day MA of 9.23, indicating a neutral trend. The MACD of -0.23 indicates Negative momentum. The RSI at 48.18 is Neutral, neither overbought nor oversold. The STOCH value of 50.67 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for IMNN.

Imunon Risk Analysis

Imunon disclosed 4 risk factors in its most recent earnings report. Imunon reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 3 New Risks
1.
Any market activity involving short selling or other market making activities could result in negative impact to the market price for our Common Stock. Q2, 2025
2.
Our Common Stock may be delisted from Nasdaq if we fail to comply with continued listing standards. Q2, 2025
3.
We will need to raise additional capital to fund our planned future operations, and we may be unable to secure such capital without significant dilutive financing transactions, or at all. If we are not able to raise additional capital, we may not be able to complete the development, testing and commercialization of our drug candidates and will not be able to continue as a going concern. Q2, 2025

Imunon Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
42
Neutral
$9.33M-0.49-107.58%83.95%
41
Neutral
$9.72M-0.28-233.50%57.97%
31
Underperform
$12.80M-0.26-98.25%63.05%
29
Underperform
$7.87M-0.44-114.81%37.42%
27
Underperform
$7.92M-0.02-1763.01%96.75%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IMNN
Imunon
4.12
-7.17
-63.51%
KZIA
Kazia Therapeutics
10.55
-14.45
-57.80%
PHIO
Phio Pharmaceuticals
1.26
-1.66
-56.85%
GNPX
Genprex
2.96
-52.04
-94.62%
GLTO
Galecto
17.78
12.11
213.58%
RNAZ
TransCode Therapeutics
9.29
-252.29
-96.45%

Imunon Corporate Events

Executive/Board ChangesBusiness Operations and Strategy
Imunon Appoints Dr. Douglas Faller as CMO
Positive
Feb 10, 2025

On February 18, 2025, IMUNON appointed Dr. Douglas Faller as Chief Medical Officer to lead the company’s clinical strategy, including advancing its lead program IMNN-001 into a Phase 3 trial for advanced ovarian cancer. Dr. Faller brings over 30 years of experience in oncology and immunology, and his appointment is expected to bolster IMUNON’s efforts in progressing its pipeline of non-viral DNA-based immunotherapies, leveraging his expertise to drive clinical programs and potential commercialization.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 22, 2025