Biorestorative Therapies, Inc. (BRTX)
:BRTX
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BioRestorative Therapies (BRTX) AI Stock Analysis

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BRTX

BioRestorative Therapies

(NASDAQ:BRTX)

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Neutral 48 (OpenAI - 4o)
Rating:48Neutral
Price Target:
BioRestorative Therapies faces significant financial challenges with ongoing net losses and negative cash flow, affecting its stock performance. However, recent improvements in financial metrics, substantial revenue growth, and promising clinical developments provide some optimism. Technical indicators suggest a neutral market position. Although valuation remains a concern due to the lack of profitability, the company's strategic focus on clinical trials and research offers potential for future growth.
Positive Factors
Revenue Growth
The significant revenue growth indicates strong market demand and successful advancement of clinical programs, enhancing long-term business prospects.
FDA Fast Track Designation
The FDA Fast Track designation for BRTX-100 accelerates its development and review process, potentially leading to faster market entry and revenue generation.
Strong Financial Position
A strong cash position with no debt provides financial stability, enabling continued investment in R&D and strategic initiatives without immediate financial pressure.
Negative Factors
Ongoing Financial Losses
Persistent financial losses highlight operational challenges and the need for sustainable revenue streams to achieve profitability, impacting long-term viability.
Negative Cash Flow
Negative cash flow indicates reliance on external financing, which may not be sustainable long-term, potentially affecting the company's operational capabilities.
Uncertain Licensing Outcomes
Uncertain outcomes in licensing agreements could delay revenue generation from partnerships, affecting strategic growth and market expansion plans.

BioRestorative Therapies (BRTX) vs. SPDR S&P 500 ETF (SPY)

BioRestorative Therapies Business Overview & Revenue Model

Company DescriptionBioRestorative Therapies (BRTX) is a biotechnology company focused on the development of innovative therapeutic solutions using cell and tissue therapies. The company operates primarily in the field of regenerative medicine, with a particular emphasis on stem cell-based therapies for the treatment of chronic lumbar disc disease and metabolic disorders. Its core products include BRTX-100, a stem cell-based therapeutic targeting disc/spine disease, and ThermoStem, a program focused on metabolic disorders including obesity and diabetes.
How the Company Makes MoneyBioRestorative Therapies generates revenue through the development and commercialization of its proprietary cell and tissue-based therapeutic products. The company aims to earn revenue by advancing its clinical programs through various stages of regulatory approval, ultimately leading to product commercialization and sales. Key revenue streams include potential licensing agreements, strategic partnerships, and collaborations with pharmaceutical companies interested in its therapies. Additionally, BRTX may secure funding from grants and research subsidies as it progresses its clinical trials and expands its research initiatives. However, being a biotechnology company in the developmental stage, BioRestorative Therapies may also rely on equity financing and other forms of investment to support its operations until its therapies are fully developed and marketed.

BioRestorative Therapies Earnings Call Summary

Earnings Call Date:Nov 12, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 26, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted significant milestones in the company's clinical and commercial development, such as the Fast Track designation for BRTX-100 and a new patent for ThermoStem. However, these were counterbalanced by a sharp revenue decline and increased net loss compared to the previous year. Despite the financial setbacks, the overall sentiment is cautiously optimistic with strategic developments and a strengthened financial position.
Q3-2025 Updates
Positive Updates
Fast Track Designation for BRTX-100
The BRTX-100 program for chronic lumbar disc disease was granted Fast Track designation by the FDA, a major milestone that enables closer collaboration with the FDA for potential accelerated Biologic License Application (BLA) approval.
ThermoStem Patent Milestone
The Japanese Patent Office issued a notice of allowance for BioRestorative Therapies' ThermoStem platform, providing broad protection terms for allogeneic, off-the-shelf brown adipose-derived stem cell technology.
Strengthening Commercial Infrastructure
BioRestorative Therapies has rebuilt and strengthened its commercial infrastructure, including supply chain, sales coverage, and distribution, with the appointment of Crystal Romano as Global Head of Commercial Operations.
Recent Financing Success
The company closed a fully subscribed financing priced above market, strengthening the balance sheet with gross proceeds of approximately $1.1 million.
Negative Updates
Significant Revenue Decline
Third-quarter 2025 revenues were $11,800, a significant decrease from $233,600 in Q3 2024, primarily due to the timing of orders for the developing biocosmeceutical revenue stream.
Increased Net Loss
The company's third-quarter 2025 net loss was $3 million or $0.33 a share, compared to a net loss of $1 million or $0.13 per share for the same period in 2024.
Company Guidance
In the third quarter of 2025, BioRestorative Therapies reported a mixed financial performance, with revenues significantly declining to approximately $11,800 from $233,600 in the same period of 2024, primarily due to timing in the biocosmeceutical revenue stream. The company reported a loss from operations of $3.7 million, up from $2.3 million in the previous year, and a net loss of $3 million or $0.33 per share, compared to a net loss of $1 million or $0.13 per share in 2024. Despite these financial challenges, BioRestorative Therapies ended the quarter with $4.5 million in cash, cash equivalents, and marketable securities, excluding $1.1 million from recent financing. On the clinical front, the company is advancing its Phase II BRTX-100 study for chronic lumbar disc disease, with enrollment nearing completion and a potential Type B FDA meeting anticipated. The company also highlighted substantial progress in its ThermoStem program targeting obesity, while continuing discussions for a potential licensing agreement. The biocosmeceuticals business shows promise, with strategic leadership changes and a focus on expanding distribution channels, although revenue guidance remains uncertain.

BioRestorative Therapies Financial Statement Overview

Summary
BioRestorative Therapies is in a challenging financial position with consistent net losses and negative cash flows, despite some revenue growth. While the balance sheet shows reduced leverage and improved equity, the company's ability to generate cash and achieve profitability remains a significant concern. Continued focus on cost management and operational efficiency will be crucial for financial stability.
Income Statement
30
Negative
BioRestorative Therapies shows a significant increase in revenue year-over-year, but it remains small in absolute terms. Despite this, the company struggles with negative profitability metrics, including persistent net losses and negative EBIT and EBITDA margins, indicating ongoing operational challenges and high costs relative to revenue.
Balance Sheet
40
Negative
The company has improved its equity position with positive stockholders' equity, and it has no current total debt, reducing financial risk. However, the frequent large net losses impact the overall asset quality, and the equity ratio has been declining, signaling a need for better asset management.
Cash Flow
35
Negative
Operating cash flow has been consistently negative, reflecting ongoing cash outflows from operations. While free cash flow has seen slight improvement, it remains negative, indicating cash burn. The reliance on financing activities to support cash needs is evident, which may not be sustainable long-term without improved operational cash generation.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue605.20K401.00K145.80K119.80K46.00K77.00K
Gross Profit571.98K372.93K-19.93K119.80K46.00K77.00K
EBITDA-12.94M-11.37M-10.25M-18.85M-26.22M-9.48M
Net Income-10.72M-8.98M-10.42M-13.22M-44.30M-11.27M
Balance Sheet
Total Assets8.52M12.28M12.61M16.43M22.45M4.35M
Cash, Cash Equivalents and Short-Term Investments7.38M10.73M11.07M14.75M21.03M3.06M
Total Debt0.000.00162.32K301.64K670.70K4.79M
Total Liabilities3.67M3.75M2.61M6.14M856.50K5.68M
Stockholders Equity4.85M8.53M10.00M10.29M21.60M-1.33M
Cash Flow
Free Cash Flow-9.59M-8.34M-6.60M-6.31M-3.36M-1.96M
Operating Cash Flow-9.52M-8.23M-6.43M-5.87M-3.33M-1.96M
Investing Cash Flow6.97M514.53K3.25M-13.48M-30.66K0.00
Financing Cash Flow1.85M7.38M2.35M0.0021.32M5.03M

BioRestorative Therapies Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.62
Price Trends
50DMA
1.52
Negative
100DMA
1.55
Negative
200DMA
1.68
Negative
Market Momentum
MACD
-0.05
Positive
RSI
35.46
Neutral
STOCH
26.15
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BRTX, the sentiment is Negative. The current price of 1.62 is above the 20-day moving average (MA) of 1.52, above the 50-day MA of 1.52, and below the 200-day MA of 1.68, indicating a bearish trend. The MACD of -0.05 indicates Positive momentum. The RSI at 35.46 is Neutral, neither overbought nor oversold. The STOCH value of 26.15 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BRTX.

BioRestorative Therapies Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$11.95M-137.09%247.62%-7.66%
44
Neutral
$12.54M-144.68%44.55%-17.92%
40
Underperform
$13.43M-0.83-110.56%29.97%
40
Underperform
$10.95M-0.41-67.47%9.63%
34
Underperform
$10.69M-0.16-273.88%73.37%
24
Underperform
$11.05M-0.16-115.39%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BRTX
BioRestorative Therapies
1.38
-0.13
-8.61%
CLRB
Cellectar Biosciences
3.50
-56.80
-94.20%
MRKR
Marker Therapeutics
0.94
-2.56
-73.14%
COCP
Cocrystal Pharma
1.10
-1.10
-50.00%
SNSE
Sensei Biotherapeutics
10.10
0.86
9.31%
AEON
AEON Biopharma
0.91
-43.14
-97.93%

BioRestorative Therapies Corporate Events

Regulatory Filings and Compliance
BioRestorative Clarifies Recent Press Release Details
Neutral
Mar 27, 2025

BioRestorative Therapies has released a statement clarifying that the information in their recent press release is being furnished and not filed, and will not be incorporated into any registration statement unless specifically identified. The company emphasizes that this does not constitute a determination or admission that the information is material or complete, nor should it be considered by investors for making investment decisions.

Regulatory Filings and Compliance
BioRestorative Therapies Issues Regulation FD Disclosure
Neutral
Feb 10, 2025

The news release does not contain specific information about BioRestorative Therapies’ industry, primary products or services, or market focus. The release appears to reference a Current Report on Form 8-K without providing substantial details about the company’s operations or implications for stakeholders.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 01, 2025