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Calidi Biotherapeutics
(CLDI)
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Rating:45Neutral
Price Target:
$2.00
▲(1900.00% Upside)
Action:Reiterated
Date:08/06/26
Overall score is held down primarily by very weak financial performance (zero revenue, persistent losses, and ongoing negative free cash flow), implying continued reliance on external funding. Technicals add pressure with a bearish trend (below key moving averages and negative MACD). Valuation is only modestly supportive because the negative P/E limits comparability and no dividend yield is available.
Positive Factors
Differentiated RedTail platform
Preclinical RedTail data show mechanisms (immune cell recruitment, IL-15 SA expression, evasion of immune clearance) that address key limitations of current solid-tumor immunotherapies. A differentiated platform can sustain durable clinical development, partnerships, and licensing options that support long-term value creation.
Negative Factors
Zero revenue and persistent losses
As a development-stage biopharma with no product revenue, Calidi depends entirely on external capital while posting large recurring losses. This structural lack of operating income means continued financing is required to reach commercial scale, constraining long-term self-sufficiency and increasing execution risk.
Read all positive and negative factors
Positive Factors
Negative Factors
Differentiated RedTail platform
Preclinical RedTail data show mechanisms (immune cell recruitment, IL-15 SA expression, evasion of immune clearance) that address key limitations of current solid-tumor immunotherapies. A differentiated platform can sustain durable clinical development, partnerships, and licensing options that support long-term value creation.
Read all positive factors
Calidi Biotherapeutics (CLDI) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$1.98M
Dividend YieldN/A
Average Volume (3M)164.15K
Price to Earnings (P/E)―
Beta (1Y)0.88
Revenue GrowthN/A
EPS Growth76.55%
CountryUS
Employees29
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-83.04
Shares Outstanding1,206,976
10 Day Avg. Volume193,319
30 Day Avg. Volume164,153
Financial Highlights & Ratios
PEG Ratio<0.01
Price to Book (P/B)1.34
Price to Sales (P/S)0.00
P/FCF Ratio-0.24
Enterprise Value/Market Cap>-0.01
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit<0.01
Enterprise Value/Ebitda<0.01
Forecast
1Y Price TargetN/A
Price Target UpsideN/A
Rating ConsensusN/A
Number of Analyst Covering0
EPS Forecast (FY)-88.32
Revenue Forecast (FY)N/A
Calidi Biotherapeutics Business Overview & Revenue Model
Company Description
Calidi Biotherapeutics, Inc. is a clinical-stage biotechnology company focused on immuno-oncology, dedicated to developing advanced immunotherapies for various cancers. The company's innovative approach centers on utilizing powerful, allogeneic (d...
How the Company Makes Money
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Calidi Biotherapeutics Financial Statement Overview
Summary
Income Statement
9
Very Negative
Balance Sheet
38
Negative
Cash Flow
12
Very Negative
| Breakdown | TTM | Dec 2025 | Mar 2025 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 0.00 | 0.00 | 0.00 | 0.00 | 45.00K | 449.00K |
| Gross Profit | -426.00K | -1.65M | 0.00 | -1.26M | -229.00K | 355.00K |
| EBITDA | -17.24M | -18.19M | -19.73M | -24.20M | -25.00M | -9.45M |
| Net Income | -19.03M | -19.91M | -22.14M | -29.22M | -25.43M | -10.93M |
Balance Sheet | ||||||
| Total Assets | 9.59M | 8.86M | 14.18M | 10.02M | 2.60M | 3.39M |
| Cash, Cash Equivalents and Short-Term Investments | 6.63M | 5.60M | 9.59M | 2.05M | 372.00K | 2.14M |
| Total Debt | 2.26M | 2.56M | 7.04M | 7.24M | 5.99M | 5.18M |
| Total Liabilities | 4.66M | 5.10M | 12.21M | 18.25M | 53.04M | 26.00M |
| Stockholders Equity | 4.93M | 3.76M | 1.53M | -8.23M | -50.44M | -22.61M |
Cash Flow | ||||||
| Free Cash Flow | -18.40M | -21.41M | -19.71M | -27.57M | -13.64M | -7.98M |
| Operating Cash Flow | -18.28M | -21.29M | -19.69M | -26.98M | -13.21M | -7.77M |
| Investing Cash Flow | -168.00K | -170.00K | -16.00K | -478.00K | -494.00K | -215.00K |
| Financing Cash Flow | 14.51M | 17.46M | 27.36M | 29.04M | 12.09M | 9.81M |
Calidi Biotherapeutics Technical Analysis
Negative
0.10
Price Trends
2.31
Negative
3.08
Negative
10.90
Negative
Market Momentum
-0.20
Negative
43.21
Neutral
66.23
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CLDI, the sentiment is Negative. The current price of 0.1 is below the 20-day moving average (MA) of 1.81, below the 50-day MA of 2.31, and below the 200-day MA of 10.90, indicating a bearish trend. The MACD of -0.20 indicates Negative momentum. The RSI at 43.21 is Neutral, neither overbought nor oversold. The STOCH value of 66.23 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CLDI.
Calidi Biotherapeutics Risk Analysis
Calidi Biotherapeutics disclosed 85 risk factors in its most recent earnings report. Calidi Biotherapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Calidi Biotherapeutics Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
50 Neutral | $7.31M | -0.34 | -162.83% | ― | ― | 75.60% | |
45 Neutral | $1.98M | -0.02 | -438.03% | ― | ― | 76.55% | |
42 Neutral | $5.13M | -0.31 | -64.10% | ― | ― | 71.38% | |
40 Underperform | $4.91M | >-0.01 | 764.53% | ― | 155.96% | 87.56% |
* Healthcare Sector Average
CLDI
Calidi Biotherapeutics
1.76
-90.40
-98.09%
GLMD
Galmed Pharmaceuticals
0.58
-0.79
-57.66%
JAGX
Jaguar Animal Health
1.06
-72.45
-98.56%
ADIL
Adial Pharmaceuticals
4.05
-5.63
-58.14%
CDIO
Cardio Diagnostics Holdings
1.75
-2.12
-54.78%
Calidi Biotherapeutics Corporate Events
Delistings and Listing ChangesShareholder MeetingsStock Split
Calidi Biotherapeutics Implements Reverse Stock Split on NYSE
Neutral
Jul 31, 2026
On June 12, 2026, Calidi Biotherapeutics stockholders approved a 1-for-16 reverse stock split of the company’s issued and outstanding common stock. The measure was implemented as a proactive step to raise the per-share trading price and supp...
Business Operations and Strategy
Calidi Biotherapeutics Plans Relocation Through New Lease Agreements
Neutral
Jul 17, 2026
On July 10, 2026, Calidi Biotherapeutics entered into a Lease Termination Agreement with 4475 Executive Drive LLC to end its existing lease for office and laboratory space at 4475 Executive Drive in San Diego, which had originally been scheduled t...
Business Operations and StrategyExecutive/Board Changes
Calidi Biotherapeutics Expands Board With New Independent Director
Positive
Jun 23, 2026
On June 17, 2026, Calidi Biotherapeutics appointed industry veteran Corazon (Corsee) Sanders, Ph.D., as a Class III independent director with a term running through the 2029 annual meeting. She also joined the Board’s Audit Committee, replac...
Business Operations and StrategyExecutive/Board ChangesShareholder MeetingsStock Split
Calidi Biotherapeutics Stockholders Approve Key Governance Measures
Positive
Jun 18, 2026
On June 12, 2026, Calidi Biotherapeutics held its 2026 Annual Meeting of Stockholders, where a quorum was reached with about 55% of eligible shares represented, and all proposals on the agenda were approved. Stockholders elected Scott Leftwich as ...
Private Placements and FinancingRegulatory Filings and Compliance
Calidi Biotherapeutics Amends Warrant in Private Placement
Neutral
May 29, 2026
On May 28, 2026, Calidi Biotherapeutics, Inc. amended and restated a previously issued warrant to an accredited investor, allowing the purchase of up to 17,391,304 unvested shares of common stock at an exercise price of $0.23 in a private placemen...
Business Operations and StrategyFinancial Disclosures
Calidi Highlights Q1 Results and RedTail Platform Progress
Positive
May 14, 2026
On May 14, 2026, Calidi Biotherapeutics reported first-quarter 2026 results and highlighted new preclinical data underscoring the potential of its RedTail-based candidates CLD-401 and CLD-501 to reshape immune activity in the tumor microenvironmen...
Private Placements and FinancingRegulatory Filings and Compliance
Calidi Biotherapeutics Issues Private Placement Warrant Financing
Neutral
May 8, 2026
On May 6, 2026, Calidi Biotherapeutics, Inc. issued a warrant to an accredited investor in a private placement, enabling the future purchase of up to 17,391,304 unvested shares of common stock at an exercise price of $0.23 per share. The warrant, ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.