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Calidi Biotherapeutics
(CLDI)
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Rating:43Neutral
Price Target:
$0.14
▼(-23.89% Downside)
Action:Reiterated
Date:06/27/26
Overall score is held down primarily by weak financial performance (zero revenue, sustained losses, and significant negative operating/free cash flow), indicating continued reliance on external financing. Technicals also reflect a sustained downtrend (below key moving averages and negative MACD). Corporate events provide some support through governance strengthening and capital-structure flexibility, but they do not materially offset the fundamental cash-burn profile.
Positive Factors
Platform Differentiation
Preclinical AACR results point to distinct biology: RedTail candidates recruit diverse immune cells and enable localized cytokine/engager expression. These durable mechanistic advantages can translate into differentiated clinical utility against solid tumors and support durable partnerships or combination strategies.
Negative Factors
No Revenue / Persistent Losses
Calidi remains a development-stage biotech with zero product revenue and large recurring losses. Over the medium term this means value creation depends entirely on clinical/regulatory milestones, making the business vulnerable to trial setbacks and requiring material external capitalization to reach commercialization.
Read all positive and negative factors
Positive Factors
Negative Factors
Platform Differentiation
Preclinical AACR results point to distinct biology: RedTail candidates recruit diverse immune cells and enable localized cytokine/engager expression. These durable mechanistic advantages can translate into differentiated clinical utility against solid tumors and support durable partnerships or combination strategies.
Read all positive factors
Calidi Biotherapeutics (CLDI) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$2.74M
Dividend YieldN/A
Average Volume (3M)164.15K
Price to Earnings (P/E)―
Beta (1Y)0.74
Revenue GrowthN/A
EPS Growth76.55%
CountryUS
Employees28
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-5.19
Shares Outstanding19,311,625
10 Day Avg. Volume193,319
30 Day Avg. Volume164,153
Financial Highlights & Ratios
PEG Ratio<0.01
Price to Book (P/B)1.34
Price to Sales (P/S)0.00
P/FCF Ratio-0.24
Enterprise Value/Market Cap-1.19
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit3.91
Enterprise Value/Ebitda0.19
Forecast
1Y Price TargetN/A
Price Target UpsideN/A
Rating ConsensusN/A
Number of Analyst Covering0
EPS Forecast (FY)-5.52
Revenue Forecast (FY)N/A
Calidi Biotherapeutics Business Overview & Revenue Model
Company Description
Calidi Biotherapeutics, Inc. is a clinical-stage biotechnology company focused on immuno-oncology, dedicated to developing advanced immunotherapies for various cancers. The company's innovative approach centers on utilizing powerful, allogeneic (d...
How the Company Makes Money
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Calidi Biotherapeutics Financial Statement Overview
Summary
Income Statement
9
Very Negative
Balance Sheet
38
Negative
Cash Flow
12
Very Negative
| Breakdown | TTM | Dec 2025 | Mar 2025 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 0.00 | 0.00 | 0.00 | 0.00 | 45.00K | 449.00K |
| Gross Profit | -833.00K | -1.65M | 0.00 | -1.26M | -229.00K | 355.00K |
| EBITDA | -17.24M | -18.19M | -19.73M | -24.20M | -25.00M | -9.45M |
| Net Income | -19.03M | -19.91M | -22.14M | -29.22M | -25.43M | -10.93M |
Balance Sheet | ||||||
| Total Assets | 9.59M | 8.86M | 14.18M | 10.02M | 2.60M | 3.39M |
| Cash, Cash Equivalents and Short-Term Investments | 6.63M | 5.60M | 9.59M | 2.05M | 372.00K | 2.14M |
| Total Debt | 2.26M | 2.56M | 7.04M | 7.24M | 5.99M | 5.18M |
| Total Liabilities | 4.66M | 5.10M | 12.21M | 18.25M | 53.04M | 26.00M |
| Stockholders Equity | 4.93M | 3.76M | 1.53M | -8.23M | -50.44M | -22.61M |
Cash Flow | ||||||
| Free Cash Flow | -18.40M | -21.41M | -19.71M | -27.57M | -13.64M | -7.98M |
| Operating Cash Flow | -18.28M | -21.29M | -19.69M | -26.98M | -13.21M | -7.77M |
| Investing Cash Flow | -168.00K | -170.00K | -16.00K | -478.00K | -494.00K | -215.00K |
| Financing Cash Flow | 14.51M | 17.46M | 27.36M | 29.04M | 12.09M | 9.81M |
Calidi Biotherapeutics Technical Analysis
Negative
0.18
Price Trends
0.18
Negative
0.30
Negative
0.82
Negative
Market Momentum
-0.01
Negative
42.61
Neutral
16.03
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CLDI, the sentiment is Negative. The current price of 0.18 is above the 20-day moving average (MA) of 0.16, above the 50-day MA of 0.18, and below the 200-day MA of 0.82, indicating a bearish trend. The MACD of -0.01 indicates Negative momentum. The RSI at 42.61 is Neutral, neither overbought nor oversold. The STOCH value of 16.03 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CLDI.
Calidi Biotherapeutics Risk Analysis
Calidi Biotherapeutics disclosed 85 risk factors in its most recent earnings report. Calidi Biotherapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Calidi Biotherapeutics Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
53 Neutral | $6.28M | -0.29 | -155.01% | ― | ― | 75.60% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
43 Neutral | $2.74M | -0.03 | ― | ― | ― | 76.55% | |
43 Neutral | $4.38M | -0.24 | -46.34% | ― | ― | 71.38% | |
41 Neutral | $11.71M | >-0.01 | 764.53% | ― | 155.96% | 87.56% |
* Healthcare Sector Average
CLDI
Calidi Biotherapeutics
0.15
-8.97
-98.37%
GLMD
Galmed Pharmaceuticals
0.57
-1.37
-70.54%
JAGX
Jaguar Animal Health
2.37
-92.13
-97.49%
ADIL
Adial Pharmaceuticals
2.80
-6.83
-70.91%
CDIO
Cardio Diagnostics Holdings
1.85
-2.30
-55.42%
Calidi Biotherapeutics Corporate Events
Business Operations and StrategyExecutive/Board Changes
Calidi Biotherapeutics Expands Board With New Independent Director
Positive
Jun 23, 2026
On June 17, 2026, Calidi Biotherapeutics appointed industry veteran Corazon (Corsee) Sanders, Ph.D., as a Class III independent director with a term running through the 2029 annual meeting. She also joined the Board’s Audit Committee, replac...
Business Operations and StrategyExecutive/Board ChangesShareholder MeetingsStock Split
Calidi Biotherapeutics Stockholders Approve Key Governance Measures
Positive
Jun 18, 2026
On June 12, 2026, Calidi Biotherapeutics held its 2026 Annual Meeting of Stockholders, where a quorum was reached with about 55% of eligible shares represented, and all proposals on the agenda were approved. Stockholders elected Scott Leftwich as ...
Private Placements and FinancingRegulatory Filings and Compliance
Calidi Biotherapeutics Amends Warrant in Private Placement
Neutral
May 29, 2026
On May 28, 2026, Calidi Biotherapeutics, Inc. amended and restated a previously issued warrant to an accredited investor, allowing the purchase of up to 17,391,304 unvested shares of common stock at an exercise price of $0.23 in a private placemen...
Business Operations and StrategyFinancial Disclosures
Calidi Highlights Q1 Results and RedTail Platform Progress
Positive
May 14, 2026
On May 14, 2026, Calidi Biotherapeutics reported first-quarter 2026 results and highlighted new preclinical data underscoring the potential of its RedTail-based candidates CLD-401 and CLD-501 to reshape immune activity in the tumor microenvironmen...
Private Placements and FinancingRegulatory Filings and Compliance
Calidi Biotherapeutics Issues Private Placement Warrant Financing
Neutral
May 8, 2026
On May 6, 2026, Calidi Biotherapeutics, Inc. issued a warrant to an accredited investor in a private placement, enabling the future purchase of up to 17,391,304 unvested shares of common stock at an exercise price of $0.23 per share. The warrant, ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.